BLASTP 2.2.17 [Aug-26-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= 0001.2677.p (390 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_002795116.1| hypothetical protein LHK_01115 [Laribacter h... 305 8e-81 ref|ZP_08160992.1| diguanylate cyclase (GGDEF) domain protein [R... 220 3e-55 ref|YP_003830357.1| GGDEF domain-containing protein [Butyrivibri... 214 3e-53 ref|YP_003830999.1| GGDEF domain-containing protein [Butyrivibri... 211 2e-52 ref|ZP_05898714.1| putative sensory box-containing diguanylate c... 208 1e-51 >ref|YP_002795116.1| hypothetical protein LHK_01115 [Laribacter hongkongensis HLHK9] gb|ACO74107.1| GGDEF domain protein [Laribacter hongkongensis HLHK9] Length = 585 Score = 305 bits (781), Expect = 8e-81, Method: Composition-based stats. Identities = 161/389 (41%), Positives = 232/389 (59%), Gaps = 7/389 (1%) Query: 1 MGWNPLSTPMRITSAEPGVVRTIDDKPAFAVYKQMLGIENDENFFFDALAFPLLLERHGT 60 +GW P+ MR+T E VRTID++PAF Y+ LGIE DENFF ++L FP+LL+R+G Sbjct: 198 LGWQPVGRSMRLTDVEGFNVRTIDNRPAFEAYRHYLGIEADENFFLNSLEFPVLLDRNGA 257 Query: 61 LLARTPAKVRADGALFFAGDVEEGEHFRLGYADLNQITESVRDIHQRAMEFSPQVVFLYS 120 LAR P V D +L F D++ GE GY + I E ++ F+P+ +FLYS Sbjct: 258 QLARIPIAVNDDLSLSFIADLQTGETVHFGYGSIPVILEQTGKTLEQVAAFAPEGLFLYS 317 Query: 121 CCGRRFLMQKDVEIESLPFQNSAPTFGFYTYAEYHGTT-QVAIHNSTLIAVTMREGNKVV 179 C R LMQ+DV++E F AP GFYTY E+ G + N+TL+AV +REG Sbjct: 318 CSTRHSLMQEDVQLEISAFHAIAPASGFYTYGEFAGQQGDYQLLNATLVAVGLREG---- 373 Query: 180 SRPTQQQAATNVL--IAERDPFIVQQVRVTARLTKFIRNMTEELEKTRAELSRMAFTDQL 237 RP Q T + + D Q R+ RL F + EL + EL +++ TD+L Sbjct: 374 ERPYGQTGHTRIEGPLKTFDAISRQHSRILQRLVYFNNVLINELVSSNRELEKLSSTDRL 433 Query: 238 TNLPNRVKLNAVLSDCVNMANRYGTPFSIILSDVDRFKSINDNYGHLAGDSVLKCVAEIL 297 T L NR++L+ ++ +++A R+ FS+IL D+D FK +ND +GH GD VL +A +L Sbjct: 434 TGLANRLRLDEEVARQISLAQRHAQEFSLILLDLDHFKLVNDQHGHQVGDRVLIEIAALL 493 Query: 298 TSNTRSTDVAGRWGGEEFLVITANTALANAVHLAEKVRMTLAQASLPNVRQITASFGVAS 357 R++D AGRWGGEEFL++ T++ +A +A+K+R T+A + +V TASFG+A Sbjct: 494 RQTLRNSDTAGRWGGEEFLIVLPQTSVESARKVADKLRRTIAGHNFGSVGPQTASFGIAV 553 Query: 358 YAVGETISALLDRADHALYAAKRSGRDRV 386 + G+T L R DHA+Y +KR GR+RV Sbjct: 554 WHTGDTAKTLFVRVDHAMYQSKRDGRNRV 582 >ref|ZP_08160992.1| diguanylate cyclase (GGDEF) domain protein [Ruminococcus albus 8] gb|EGC01246.1| diguanylate cyclase (GGDEF) domain protein [Ruminococcus albus 8] Length = 575 Score = 220 bits (561), Expect = 3e-55, Method: Composition-based stats. Identities = 139/389 (35%), Positives = 197/389 (50%), Gaps = 25/389 (6%) Query: 2 GWNPLSTPMRITSAEPGVVRTIDDKPAFAVYKQMLGIENDENFFFDALAFPLLLERHGTL 61 GW PL +T +E + ID PA+ VY++ L I+NDE+FF L FP L +G Sbjct: 203 GWKPLGKVFHVTRSEGSRLYEIDHTPAYEVYRKYLNIKNDEHFFNHTLEFPFLYLHNGIN 262 Query: 62 LARTPAKVRADGALFFAGDVEEGEHFRLGYADLNQITESVRDIHQRAMEFSPQVVFLYSC 121 + R P + DG+L D+E +L Y D I ESVR+ ++ EF P+ V ++SC Sbjct: 263 ILRAPTESLPDGSLIMTSDMESDVTAQLAYGDPGTILESVREEGRKIYEFKPETVEIFSC 322 Query: 122 CGRR-FLMQKDVEIESLPFQNSAPTFGFYTYAEYHGTT-QVAIHNSTLIAVTMREGNKVV 179 RR F ++ ES PFQN APT+GFYT E+ T V HN T++ V MREG+ Sbjct: 323 AARRSFWGNSEISKESQPFQNIAPTYGFYTSGEFCRTNGHVNQHNVTMVLVGMREGDA-- 380 Query: 180 SRPTQQQAATNVLIAERDPFIVQQVRVTARLTKFIRNMTEELEKTRAELSRMAFTDQLTN 239 P + A V D ++ + RL +I +LE+ A TD LT Sbjct: 381 --PAGKTAELYV----EDGEFTGKMALINRLANYINAAFRDLEEA-------AVTDGLTR 427 Query: 240 LPNRVKLNAVLSDCVNMANRYGTPFSIILSDVDRFKSINDNYGHLAGDSVLKCVAEILTS 299 L NR ++ + + + R G P ++I+ D+D FKS+ND YGH GD+V+ +A +L Sbjct: 428 LLNRAEIQRRIGERL----RSGEPLTLIMIDIDNFKSVNDTYGHNEGDNVIVGLANMLHK 483 Query: 300 NT---RSTDVAGRWGGEEFLVITANTALANAVHLAEKVRMTLAQASLPNVRQITASFGVA 356 + AGRWGGEEF+V+ L + A + A P T S GV Sbjct: 484 GIDVHNPSACAGRWGGEEFMVMMPYD-LVYTIPAARDMCSDFAALEFPLAGHRTISIGVT 542 Query: 357 SYAVGETISALLDRADHALYAAKRSGRDR 385 + +T+ LL R D ALY AK SG++R Sbjct: 543 AAKPEDTLDELLIRVDSALYDAKHSGKNR 571 >ref|YP_003830357.1| GGDEF domain-containing protein [Butyrivibrio proteoclasticus B316] gb|ADL33775.1| GGDEF domain-containing protein [Butyrivibrio proteoclasticus B316] Length = 589 Score = 214 bits (544), Expect = 3e-53, Method: Composition-based stats. Identities = 123/390 (31%), Positives = 199/390 (51%), Gaps = 6/390 (1%) Query: 1 MGWNPLSTPMRITSAEPGVVRTIDDKPAFAVYKQMLGIENDENFFFDALAFPLLLERHGT 60 +GW PL M T E + +D PA +Y + L I+ +++FF + L FP++ +H Sbjct: 199 IGWKPLGKDMTATRIEGKRLYELDGVPATQIYSKYLDIQANDDFFSNILEFPIMSTQHDQ 258 Query: 61 LLARTPAKVRAD-GALFFAGDVEEGEHFRLGYADLNQITESVRDIHQRAMEFSPQVVFLY 119 + R P + G++ A D+++G L Y D + I V ++ + +F+PQ VFLY Sbjct: 259 HVLRLPFSCDPESGSILLAADLDKGTKVNLSYGDPDVIKGDVAELVEHVKDFAPQAVFLY 318 Query: 120 SCCGRRFLMQKDVEIESLPFQNSAPTFGFYTYAEYHGTTQVAI-HNSTLIAVTMREGNKV 178 SC RR + + E+ PF AP GFY+ E + I H+ TLIA++MREG Sbjct: 319 SCGVRRLYWKYLINKETGPFSQVAPVSGFYSSGEIMRMGKYLIEHHVTLIAISMREGEHA 378 Query: 179 VSRPTQQQAATNVLIAERDPFIVQQVRVTARLTKFIRNMTEELEKTRAELSRMAFTDQLT 238 ++PT + T + E+ + Q+ + RL FI EL + EL + A TD LT Sbjct: 379 KAQPTGEGDKTIEMSEEQK--MHGQISMVRRLATFINVTAAELRQANDELRQAADTDALT 436 Query: 239 NLPNRVKLNAVLSDCVNMANRYGTPFSIILSDVDRFKSINDNYGHLAGDSVLKCVAEILT 298 L NR ++ V+ + G + ++D+D FK +ND YGH GD +L ++++L Sbjct: 437 GLSNRRVIDKVVRSTIATFKTMGIDIVLGIADIDDFKVVNDTYGHAEGDKILVAISDMLN 496 Query: 299 SNT--RSTDVAGRWGGEEFLVITANTALANAVHLAEKVRMTLAQASLPNVRQITASFGVA 356 + + GRWGGEEFL + ++ A L +++R +A + T S G+ Sbjct: 497 EQICRIPSSLIGRWGGEEFLFMCPRVSIEEARDLLDEIRQKIADTEFGAIGHRTISVGMT 556 Query: 357 SYAVGETISALLDRADHALYAAKRSGRDRV 386 + ++ + RAD ALY AK SG++R+ Sbjct: 557 EFKNDDSADDVFCRADQALYEAKGSGKNRI 586 >ref|YP_003830999.1| GGDEF domain-containing protein [Butyrivibrio proteoclasticus B316] gb|ADL34417.1| GGDEF domain-containing protein [Butyrivibrio proteoclasticus B316] Length = 597 Score = 211 bits (536), Expect = 2e-52, Method: Composition-based stats. Identities = 134/403 (33%), Positives = 201/403 (49%), Gaps = 32/403 (7%) Query: 1 MGWNPLSTPMRITSAE-PGVVRTIDDKPAFAVYKQMLGIENDENFFFDALAFPLLLERHG 59 +G+ + M +T E ++ ID +PA VY + L + + F + FP++ R Sbjct: 207 LGFKEIGVEMVVTKTEGDNIIAEIDHRPATEVYSKYLKVSPGKYFVENVCEFPMIFHRRD 266 Query: 60 TLLARTPAKVRADGALFFAGDVEEGEHFRLGYAD----LNQITESVRDIHQRAMEFSPQV 115 ++AR P+ D ++ F DV +GE RL Y L+ I+ESVR I F+P+ Sbjct: 267 CVIARVPSAYGEDNSIHFTSDVVKGEKLRLSYGSADNLLDTISESVRGIKN----FNPEA 322 Query: 116 VFLYSCCGRRFLMQKDVEIESLPFQNSAPTFGFYT-YAEYHGTTQVA--IHNSTLIAVTM 172 VFL+ C R +++ E+ ++ P YAE + + + + NS L+AV + Sbjct: 323 VFLFECGNRVRFLKEKASSETASYRILYPEVSVAVGYAEIYESASGSGGVLNSALVAVGL 382 Query: 173 REGNKVVS--RP-TQQQAATNVLIAERD--PFIVQQVRVTARLTKFIRNMTEELEKTRAE 227 +E RP T + ERD PF+ R+ F+ + EL+ E Sbjct: 383 KEDPDAEDEFRPGVTYIDDTQIQEDERDYIPFV-------DRILNFLERTSIELDSMNKE 435 Query: 228 LSRMAFTDQLTNLPNRV----KLNAVLSDCVNMANRYGTPFSIILSDVDRFKSINDNYGH 283 L ++A+TDQLT + NR K+N +LS+C NR SII D+D FK +ND YGH Sbjct: 436 LGKIAYTDQLTRIYNRWELENKVNEILSECNEGGNRA----SIIFMDIDHFKHVNDTYGH 491 Query: 284 LAGDSVLKCVAEILTSNTRSTDVAGRWGGEEFLVITANTALANAVHLAEKVRMTLAQASL 343 GD VL+ +I+ N + V GRWGGEEF+ + +T + AV AE +R + Sbjct: 492 DVGDMVLRASVDIIRDNLEAQHVFGRWGGEEFIYVLPDTGIDEAVEFAENLRKQIQDNCF 551 Query: 344 PNVRQITASFGVASYAVGETISALLDRADHALYAAKRSGRDRV 386 V+ IT SFGV G+T+ + RAD LY AK GR+RV Sbjct: 552 VTVQHITMSFGVTQNIAGDTLETFVKRADDGLYKAKEGGRNRV 594 >ref|ZP_05898714.1| putative sensory box-containing diguanylate cyclase [Selenomonas sputigena ATCC 35185] ref|YP_004414675.1| diguanylate cyclase [Selenomonas sputigena ATCC 35185] gb|EEX77314.1| putative sensory box-containing diguanylate cyclase [Selenomonas sputigena ATCC 35185] gb|AEC01216.1| diguanylate cyclase [Selenomonas sputigena ATCC 35185] Length = 589 Score = 208 bits (530), Expect = 1e-51, Method: Composition-based stats. Identities = 125/390 (32%), Positives = 195/390 (50%), Gaps = 15/390 (3%) Query: 2 GWNPLSTPMRITS-AEPGVVRTIDDKPAFAVYKQMLGIENDENFFFDALAFPLLLERHGT 60 GW P ++IT A+ + +D+KPA + LGI + FP+ L+R+G Sbjct: 207 GWKPFGPEVQITRMADERTIVELDEKPASEFFSHYLGIRHCWESLASVETFPMCLKRNGA 266 Query: 61 LLARTPAKVRADGALFFAGDVEEGEHFRLGYADLNQITESVRDIHQRAMEFSPQVVFLYS 120 LAR + ADG ++ + D+ EGE R+ D I + H EFSP+ VF+ + Sbjct: 267 TLARRLMDIHADGCVYVSADLREGERLRIASGDPIAIISEAQRTHAELCEFSPEAVFIVN 326 Query: 121 CCGRRFLMQKDVEIESLPFQNSAPTFGFYTYAEY-HGTTQVAIHNSTLIAVTMREGNKVV 179 C G ++Q++ E + PT GFY+YAE+ + N ++++ REG Sbjct: 327 CMGHYIMLQQNNVYEYAAISRAVPTHGFYSYAEFFRSKGKFMKTNLMMVSIGFREG---- 382 Query: 180 SRPTQQQAATNVLIAERDPFIVQQVRVTARLTKFIRNMTEELEKTRAELSRMAFTDQLTN 239 P + V P +Q + A L F+ MT+E E ++L +A D LT Sbjct: 383 -EPKEAPIYKPV-----SPQFGEQTSIIAHLVHFVDAMTKEWESAHSKLVVLAERDALTG 436 Query: 240 LPNRVKLNAVLSDCVNMANRYGTPFSIILSDVDRFKSINDNYGHLAGDSVLKCVAEILTS 299 L NR + D ++ A PF++++ D+D FK IND +GH GD L +A+IL S Sbjct: 437 LMNRRAMERSFKDILHDALASDIPFAVMMLDMDDFKGINDTFGHAMGDEALVALADILRS 496 Query: 300 NTRSTDVAGRWGGEEFLVITANTALANAVHLAEKVRMTLAQASL--PNVRQITASFGVAS 357 + RS D+ RWGG+EF VI + A A + E++ + SL P+ R + S GV Sbjct: 497 SVRSVDIVSRWGGDEFFVILTHADRAAAERVVERIHRGASSLSLLMPDKRSVGLSIGVTL 556 Query: 358 YAVGETISALLDRADHALYAAKRS-GRDRV 386 + +T + RAD ALY +KR+ G+++V Sbjct: 557 SSAHDTPETVFQRADAALYESKRTAGKNKV 586