BLASTP 2.2.17 [Aug-26-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= 0001.2578.p (490 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_004350041.1| major facilitator transporter [Burkholderia ... 412 e-113 ref|ZP_06548483.1| major Facilitator Superfamily protein [Klebsi... 402 e-110 ref|YP_002238065.1| transporter major facilitator family [Klebsi... 401 e-109 ref|YP_001773899.1| major facilitator transporter [Burkholderia ... 399 e-109 ref|YP_003911164.1| major facilitator superfamily protein [Burkh... 398 e-108 >ref|YP_004350041.1| major facilitator transporter [Burkholderia gladioli BSR3] gb|AEA64529.1| major facilitator transporter [Burkholderia gladioli BSR3] Length = 492 Score = 412 bits (1059), Expect = e-113, Method: Composition-based stats. Identities = 255/454 (56%), Positives = 316/454 (69%) Query: 16 PRRWLAFAVLLVGAFLPPLDFFIVNVALPSIRNGLGADPAEVQLVISGYAAVYAVFLITG 75 PRRW F++LLVGAFLPPLDFFIVNVALPSI+ LG + QLVIS YAA YAV LITG Sbjct: 11 PRRWAMFSILLVGAFLPPLDFFIVNVALPSIQGELGTSSSAEQLVISSYAACYAVTLITG 70 Query: 76 GRLGDLLGRKRVFLAGLAGFGLASTLCGVASSPAMLIAGRLLQGLSAAIMAPQGLASIQA 135 GRLGDL GR R+F GL GF AS LCG+A SP LI GR LQG++AAIMAPQ LASIQA Sbjct: 71 GRLGDLFGRGRMFFLGLTGFAAASLLCGIAWSPWTLIIGRALQGVTAAIMAPQALASIQA 130 Query: 136 LFPERERARALSMYGATIGLAAIVAQAFGGLLIAANLGDLQWRIIFLINLPIVAIVFLVG 195 +FPE E++ ALS+YGA GLA+++ QA GG+LI+ NL + WR IFL+NLP+ +V L G Sbjct: 131 IFPETEKSLALSLYGAVFGLASVIGQALGGILISLNLFGMAWRTIFLVNLPVAILVVLFG 190 Query: 196 IPLLPDTRSPHAARLDWMGVLLCALTLGLLVVPLVKGPEDGWPWWTCLMLIASPLFAMAF 255 IPLL +TR+ HA +LD +G L TLG L+VPL++G GWP W+CL L A P A F Sbjct: 191 IPLLKETRAEHARKLDLVGTALSMATLGALIVPLIEGRAAGWPLWSCLCLGAVPALAWIF 250 Query: 256 WRHEQRLTQRGATPLVSPKLARVPGLVVGLVGVLFFYVVSAFFLTFSIYLQEAIGMSALA 315 WR+E RL +G PL+ P R PGL L+ L FY ++AFFL FS+YLQ A+ + AL+ Sbjct: 251 WRYESRLAGKGGAPLLDPTALRAPGLGRALLVALLFYAIAAFFLLFSVYLQNALHVDALS 310 Query: 316 TGLMFIPCGLGFFLGPLMTPAAARRFGRWTPVLGMSLEVIGALLLSAVVAMARDGQAPAL 375 GL+F+P G GF LGPL TP AAR G + GM LEV+G L+ ++A + G PA Sbjct: 311 AGLVFLPFGAGFLLGPLSTPLAARMLGAYVNPFGMGLEVLGFGGLAGLIAASPVGMPPAS 370 Query: 376 AGVIVALGLIGVGQGIAVPTLVRSVIERAPADGSGMVAGIVNSALQISAALGVAVIGSVF 435 A + + L IG GQG+A+PTL+R V R SGM+AGI +S LQIS AL VAVIG +F Sbjct: 371 APLAIVLFTIGFGQGLALPTLMRMVTGRVAPTMSGMIAGIASSTLQISTALSVAVIGGIF 430 Query: 436 FSLAGRSHTPSSLAHALSWAMLCVAASLAVAALL 469 +++ G P+S+AHA AMLC+A LAV A L Sbjct: 431 YTVLGSRQDPASIAHAFVVAMLCIAFCLAVGATL 464 >ref|ZP_06548483.1| major Facilitator Superfamily protein [Klebsiella sp. 1_1_55] gb|EFD86503.1| major Facilitator Superfamily protein [Klebsiella sp. 1_1_55] Length = 493 Score = 402 bits (1034), Expect = e-110, Method: Composition-based stats. Identities = 237/456 (51%), Positives = 316/456 (69%) Query: 14 AHPRRWLAFAVLLVGAFLPPLDFFIVNVALPSIRNGLGADPAEVQLVISGYAAVYAVFLI 73 A PRRW F +LLVGAFLPPLDFFIVNVALP+I+ LGA + QLVIS YAAVYAV L+ Sbjct: 9 AEPRRWAMFVILLVGAFLPPLDFFIVNVALPAIQGELGASSSAEQLVISSYAAVYAVTLV 68 Query: 74 TGGRLGDLLGRKRVFLAGLAGFGLASTLCGVASSPAMLIAGRLLQGLSAAIMAPQGLASI 133 TGGRLGD+ GR ++F GL GF AS LCG+A SP +LI GR+LQG +AAIMAPQ LAS+ Sbjct: 69 TGGRLGDIYGRGKMFFLGLVGFAAASLLCGLAWSPWVLITGRVLQGATAAIMAPQALASV 128 Query: 134 QALFPERERARALSMYGATIGLAAIVAQAFGGLLIAANLGDLQWRIIFLINLPIVAIVFL 193 QA+FPE E+ ALS+YGA GLA+++ Q GG+LI+ NL L WR IFL+NLP+ +V L Sbjct: 129 QAIFPEAEKPLALSIYGAVFGLASVIGQVLGGILISVNLFHLGWRAIFLVNLPVALLVIL 188 Query: 194 VGIPLLPDTRSPHAARLDWMGVLLCALTLGLLVVPLVKGPEDGWPWWTCLMLIASPLFAM 253 G+PL+ +TR+ A +LD +G+LL + L L+VPL++G E GWPWWT L +A PL Sbjct: 189 CGLPLVKETRAQSAQKLDPVGMLLATVMLSTLIVPLIEGREAGWPWWTWLSFLAFPLLVS 248 Query: 254 AFWRHEQRLTQRGATPLVSPKLARVPGLVVGLVGVLFFYVVSAFFLTFSIYLQEAIGMSA 313 WR+E+RL+Q G +PL+ P + R PGL GL VL FY + AFFL FS+YLQ+A+ ++A Sbjct: 249 LLWRYERRLSQHGGSPLLDPTVLRAPGLSQGLAIVLLFYSIGAFFLLFSVYLQDALHLNA 308 Query: 314 LATGLMFIPCGLGFFLGPLMTPAAARRFGRWTPVLGMSLEVIGALLLSAVVAMARDGQAP 373 L GL+F+P G+GF +GPL+TP R G + +GM E G L+ ++A G P Sbjct: 309 LNAGLIFLPFGVGFLIGPLLTPFLRRFAGNYLSAIGMGCETSGLAGLAGLIANTMTGTPP 368 Query: 374 ALAGVIVALGLIGVGQGIAVPTLVRSVIERAPADGSGMVAGIVNSALQISAALGVAVIGS 433 + + + L + G+GQG+A+PTLVR V R + SGM+AG+ +S LQIS AL VA+IG Sbjct: 369 PMLPLALLLFVTGLGQGLAMPTLVRMVTGRVAPEFSGMIAGVTSSTLQISTALSVAIIGG 428 Query: 434 VFFSLAGRSHTPSSLAHALSWAMLCVAASLAVAALL 469 +F+S+ + +++ HA A+L +A LA A L Sbjct: 429 IFYSMLENGRSGANITHAFIVALLTMAVCLATGAGL 464 >ref|YP_002238065.1| transporter major facilitator family [Klebsiella pneumoniae 342] gb|ACI09925.1| transporter, major facilitator family [Klebsiella pneumoniae 342] Length = 493 Score = 401 bits (1031), Expect = e-109, Method: Composition-based stats. Identities = 238/456 (52%), Positives = 316/456 (69%) Query: 14 AHPRRWLAFAVLLVGAFLPPLDFFIVNVALPSIRNGLGADPAEVQLVISGYAAVYAVFLI 73 A PRRW F +LLVGAFLPPLDFFIVNVALP+I+ LGA + QLVIS YAAVYAV LI Sbjct: 9 AEPRRWAMFVILLVGAFLPPLDFFIVNVALPAIQGELGASSSAEQLVISSYAAVYAVTLI 68 Query: 74 TGGRLGDLLGRKRVFLAGLAGFGLASTLCGVASSPAMLIAGRLLQGLSAAIMAPQGLASI 133 TGGRLGD+ GR ++F GL GF AS LCG+A SP +LI GR+LQG +AAIMAPQ LAS+ Sbjct: 69 TGGRLGDIYGRGKMFFLGLVGFAAASLLCGLAWSPWVLITGRVLQGATAAIMAPQALASV 128 Query: 134 QALFPERERARALSMYGATIGLAAIVAQAFGGLLIAANLGDLQWRIIFLINLPIVAIVFL 193 QA+FPE E+ ALS+YGA GLA+++ Q GG+LI+ NL L WR IFL+NLP+ +V L Sbjct: 129 QAIFPEAEKPLALSIYGAVFGLASVIGQVLGGILISVNLFHLGWRAIFLVNLPVALLVIL 188 Query: 194 VGIPLLPDTRSPHAARLDWMGVLLCALTLGLLVVPLVKGPEDGWPWWTCLMLIASPLFAM 253 G+PL+ +TR+ A +LD +G+LL + L L+VPL++G E GWPWWT L +A PL Sbjct: 189 CGLPLVKETRAQSAQKLDPVGMLLATVMLSTLIVPLIEGREAGWPWWTWLSFLAFPLLVS 248 Query: 254 AFWRHEQRLTQRGATPLVSPKLARVPGLVVGLVGVLFFYVVSAFFLTFSIYLQEAIGMSA 313 WR+E+RL+Q G +PL+ P + R PGL GL VL FY + AFFL FS+YLQ+A+ ++A Sbjct: 249 LLWRYERRLSQHGGSPLLDPMVLRAPGLGQGLAIVLLFYSIGAFFLLFSVYLQDALHLNA 308 Query: 314 LATGLMFIPCGLGFFLGPLMTPAAARRFGRWTPVLGMSLEVIGALLLSAVVAMARDGQAP 373 L GL+F+P G+GF +GPL+TP R G + +GM E G L+ ++A G P Sbjct: 309 LNAGLIFLPFGVGFLIGPLLTPFLRRFAGNYLSAIGMGCETSGLAGLAGLIANTMTGAPP 368 Query: 374 ALAGVIVALGLIGVGQGIAVPTLVRSVIERAPADGSGMVAGIVNSALQISAALGVAVIGS 433 + + + L + G+GQG+A+PTLVR V R + SGM+AG+ +S LQIS AL VA+IG Sbjct: 369 PMLPLALLLFVTGLGQGLAMPTLVRMVTGRVAPEFSGMIAGVTSSTLQISTALSVAIIGG 428 Query: 434 VFFSLAGRSHTPSSLAHALSWAMLCVAASLAVAALL 469 +F+S+ + +++ HA A+L +A LA A L Sbjct: 429 IFYSMLENGRSGANITHAFIVALLTMAVCLATGAGL 464 >ref|YP_001773899.1| major facilitator transporter [Burkholderia cenocepacia MC0-3] gb|ACA95404.1| major facilitator superfamily MFS_1 [Burkholderia cenocepacia MC0-3] Length = 493 Score = 399 bits (1025), Expect = e-109, Method: Composition-based stats. Identities = 250/454 (55%), Positives = 319/454 (70%) Query: 16 PRRWLAFAVLLVGAFLPPLDFFIVNVALPSIRNGLGADPAEVQLVISGYAAVYAVFLITG 75 PRRW F+VLLVGAFLPPLDFFIVNVALPSIR+ LGA + QLVIS YA +YAV LITG Sbjct: 11 PRRWAMFSVLLVGAFLPPLDFFIVNVALPSIRSELGASSSAEQLVISSYAGLYAVTLITG 70 Query: 76 GRLGDLLGRKRVFLAGLAGFGLASTLCGVASSPAMLIAGRLLQGLSAAIMAPQGLASIQA 135 GRLGDL GR RVF GL GF +ASTLCG+ASSP LI GR LQG++AAIMAPQ LASIQA Sbjct: 71 GRLGDLFGRGRVFFLGLIGFAIASTLCGLASSPWTLIVGRALQGVTAAIMAPQALASIQA 130 Query: 136 LFPERERARALSMYGATIGLAAIVAQAFGGLLIAANLGDLQWRIIFLINLPIVAIVFLVG 195 +FPE E+ ALS+YGA GLAA+V QA GG+LI+ NL +L WR IFL+NLP+ +V L G Sbjct: 131 IFPESEKPLALSLYGAVFGLAAVVGQALGGILISLNLLNLGWRTIFLVNLPLAILVVLFG 190 Query: 196 IPLLPDTRSPHAARLDWMGVLLCALTLGLLVVPLVKGPEDGWPWWTCLMLIASPLFAMAF 255 IPLL +TR+ HA +LD G L LTLG L+VPL++G E GWP W + L+A P A F Sbjct: 191 IPLLKETRAQHARKLDLGGTALSMLTLGALIVPLIEGREAGWPAWAWVSLLAVPALAWGF 250 Query: 256 WRHEQRLTQRGATPLVSPKLARVPGLVVGLVGVLFFYVVSAFFLTFSIYLQEAIGMSALA 315 WR+E+RL RG PL+ P R PGL L+ L Y + FFL FS+YLQ A+ + AL+ Sbjct: 251 WRYERRLGSRGGAPLLDPTALRAPGLGRALLIALLLYSIGTFFLLFSVYLQNALHVDALS 310 Query: 316 TGLMFIPCGLGFFLGPLMTPAAARRFGRWTPVLGMSLEVIGALLLSAVVAMARDGQAPAL 375 GL+F+P G+GF LGPL TP +R G + GMSLE++G + L+ ++ + G Sbjct: 311 AGLVFLPFGVGFLLGPLSTPVCSRVIGAYVNPFGMSLEIVGLVGLAWLIDVTPVGMPLTA 370 Query: 376 AGVIVALGLIGVGQGIAVPTLVRSVIERAPADGSGMVAGIVNSALQISAALGVAVIGSVF 435 + V L +IG GQG+A+PTL+R V R SGM+AGIV+S LQ+S +L VA+IG +F Sbjct: 371 VPLAVVLFVIGFGQGLALPTLMRMVTGRVAPALSGMIAGIVSSTLQVSTSLSVAIIGGIF 430 Query: 436 FSLAGRSHTPSSLAHALSWAMLCVAASLAVAALL 469 +++ G P+++AHA A+L +++ LA+ A L Sbjct: 431 YTVLGTRQDPAAIAHAFIVALLSISSFLAIGAAL 464 >ref|YP_003911164.1| major facilitator superfamily protein [Burkholderia sp. CCGE1003] gb|ADN61873.1| major facilitator superfamily MFS_1 [Burkholderia sp. CCGE1003] Length = 493 Score = 398 bits (1022), Expect = e-108, Method: Composition-based stats. Identities = 252/465 (54%), Positives = 321/465 (69%), Gaps = 1/465 (0%) Query: 5 LSSTRAEGAAHPRRWLAFAVLLVGAFLPPLDFFIVNVALPSIRNGLGADPAEVQLVISGY 64 +S R+E + PRRW F+VLLVGAFLPPLDFFIVNVALPSIR L A + QLVIS Y Sbjct: 1 MSRNRSE-SPDPRRWAMFSVLLVGAFLPPLDFFIVNVALPSIRAELTASSSAEQLVISSY 59 Query: 65 AAVYAVFLITGGRLGDLLGRKRVFLAGLAGFGLASTLCGVASSPAMLIAGRLLQGLSAAI 124 A +YAV LITGGRLGDL GR RVF GL GF ASTLCG+A+SP LIAGR LQG++AAI Sbjct: 60 AGLYAVTLITGGRLGDLFGRGRVFFLGLIGFAAASTLCGLANSPWTLIAGRALQGVTAAI 119 Query: 125 MAPQGLASIQALFPERERARALSMYGATIGLAAIVAQAFGGLLIAANLGDLQWRIIFLIN 184 MAPQ LASIQA+FPE E+ ALS+YGA GLAA++ QA GG+LI+ +L +L WR IFL+N Sbjct: 120 MAPQALASIQAIFPESEKPLALSLYGAVFGLAAVIGQALGGILISLDLLNLGWRTIFLVN 179 Query: 185 LPIVAIVFLVGIPLLPDTRSPHAARLDWMGVLLCALTLGLLVVPLVKGPEDGWPWWTCLM 244 LP+ +V + GIPLL +TR+ HA +LD G L LTLG L+VPL++G E GWP W + Sbjct: 180 LPLAILVVVFGIPLLKETRAQHARKLDLGGTALSMLTLGALIVPLIEGREAGWPVWAWVS 239 Query: 245 LIASPLFAMAFWRHEQRLTQRGATPLVSPKLARVPGLVVGLVGVLFFYVVSAFFLTFSIY 304 LIA P A FWR+E+RL RG PL+ P R PGL L+ L Y + AFFL FS+Y Sbjct: 240 LIAVPALAGFFWRYERRLGSRGGAPLLDPAALRAPGLGQALLIALLLYSIGAFFLLFSVY 299 Query: 305 LQEAIGMSALATGLMFIPCGLGFFLGPLMTPAAARRFGRWTPVLGMSLEVIGALLLSAVV 364 LQ A+ + AL+ GL+F+P G+GF LGPL TP +R G + LGM+LEV+G + L+ ++ Sbjct: 300 LQNALHVDALSAGLVFLPFGVGFLLGPLSTPFFSRFIGAYVNPLGMALEVVGLVGLAWLI 359 Query: 365 AMARDGQAPALAGVIVALGLIGVGQGIAVPTLVRSVIERAPADGSGMVAGIVNSALQISA 424 G A A + L + G GQG+A+PTL+R V R SGM+AGI +S LQ+S Sbjct: 360 EATPTGTPLASAPLAAVLFVTGFGQGLALPTLMRMVTGRVAPALSGMIAGIASSTLQVST 419 Query: 425 ALGVAVIGSVFFSLAGRSHTPSSLAHALSWAMLCVAASLAVAALL 469 +L VA+IG +F+++ G P+S+AHA A+L ++ L V A L Sbjct: 420 SLSVAIIGGIFYTVLGARQDPASIAHAFIVALLSISLFLTVGAAL 464