BLASTP 2.2.17 [Aug-26-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= 0001.2547.p (423 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003774282.1| Na+-driven multidrug efflux pump protein [He... 530 e-148 ref|ZP_04579189.1| inner membrane transmembrane protein [Oxaloba... 409 e-112 ref|ZP_04576134.1| MATE efflux family protein [Oxalobacter formi... 398 e-109 ref|ZP_02362578.1| multidrug resistance protein NorM, putative [... 372 e-101 ref|ZP_02355435.1| multidrug resistance protein NorM, putative [... 371 e-100 >ref|YP_003774282.1| Na+-driven multidrug efflux pump protein [Herbaspirillum seropedicae SmR1] gb|ADJ62374.1| inner membrane transmembrane (Na+-driven multidrug efflux pump) protein [Herbaspirillum seropedicae SmR1] Length = 454 Score = 530 bits (1365), Expect = e-148, Method: Composition-based stats. Identities = 361/415 (86%), Positives = 389/415 (93%) Query: 1 MVSRFSALDLGALALGVSIYVSVFVGLSGVLQALQPTIGQLYGAGRVGEIGNEVKQGMWL 60 MVSRFSALDL ALALGVSIYVSVFVGLSGVLQALQPTIGQL+GAGR EIG+EV+QGMWL Sbjct: 34 MVSRFSALDLAALALGVSIYVSVFVGLSGVLQALQPTIGQLFGAGRHDEIGDEVRQGMWL 93 Query: 61 AVLLSIVGSLILMFSPLFLAVAKASPELVEKATLYLRIEALALPATLFFRVYSSLNTALA 120 AV LS++G+L+LMFSPLFL+VAKASPELVEKATLYLRIEALALPATLFFRVYS+LNTA+A Sbjct: 94 AVFLSVIGALVLMFSPLFLSVAKASPELVEKATLYLRIEALALPATLFFRVYSALNTAIA 153 Query: 121 RPKMVMALQLGGLLLKLPLNALLIFGGLGLPAFGGPGCAIATTLIAWLMMIAAWLLVARL 180 RPKMVMA+Q+ GLLLKLPLNALLIFGGLGLPAFGGPGCAIATTLIAWLMM+AAWLLVARL Sbjct: 154 RPKMVMAIQVCGLLLKLPLNALLIFGGLGLPAFGGPGCAIATTLIAWLMMLAAWLLVARL 213 Query: 181 PLYRPLKLFGSGFVAPSWKSQRTLLLLGIPIGMSYFIEVTAFTLMAVFIARLGAVPVAGH 240 P+YRPLKLFG GFVAPSWK+ R LL LGIPIGMSYFIEVTAFTLMAVFIARLGAVPVAGH Sbjct: 214 PVYRPLKLFGRGFVAPSWKTLRRLLWLGIPIGMSYFIEVTAFTLMAVFIARLGAVPVAGH 273 Query: 241 QIAANVGTVLYMLPLSIASATSTLVAQAIGGGNMAEAKKIGRAGIRLAVSLSVVIGVIVW 300 QI ANVGTVLYMLPLSIASATSTLVAQAIGGGN A AKKIG AGIRLA++LSV++G++V+ Sbjct: 274 QITANVGTVLYMLPLSIASATSTLVAQAIGGGNFAVAKKIGNAGIRLAIALSVLVGLVVY 333 Query: 301 FLREHIIRAYTPDPVIVGAALPLFLYIAFYQLFDSMQVTTAFVLRAYKVAVVPTVIYAVT 360 LR IIRAYTPDP+I+GAALPLFLYIAFYQLFDS+QVTTAFVLRAYKVAVVPTVIYAVT Sbjct: 334 CLRGQIIRAYTPDPLIIGAALPLFLYIAFYQLFDSLQVTTAFVLRAYKVAVVPTVIYAVT 393 Query: 361 LWGVGLGGGYLLGLDPLGMAPAALHGPVGFWAANSVSLGLVAVGLLAYLRVIQQR 415 LWGVGLGGGYLLGLDPLG+ P L GP GFW ANS SLGLV +GLL YLR IQ+R Sbjct: 394 LWGVGLGGGYLLGLDPLGLTPPNLLGPAGFWLANSASLGLVGIGLLYYLRHIQRR 448 >ref|ZP_04579189.1| inner membrane transmembrane protein [Oxalobacter formigenes OXCC13] gb|EEO30162.1| inner membrane transmembrane protein [Oxalobacter formigenes OXCC13] Length = 470 Score = 409 bits (1051), Expect = e-112, Method: Composition-based stats. Identities = 232/417 (55%), Positives = 310/417 (74%), Gaps = 1/417 (0%) Query: 1 MVSRFSALDLGALALGVSIYVSVFVGLSGVLQALQPTIGQLYGAGRVGEIGNEVKQGMWL 60 MVSR+S DLGALA+ S+Y+SV+V L+GV+Q+L PT GQL+GAG+ E+G E KQG+WL Sbjct: 38 MVSRYSVTDLGALAVAASVYISVYVALNGVMQSLAPTFGQLFGAGKFPEMGKEAKQGVWL 97 Query: 61 AVLLSIVGSLILMFSPLFLAVAKASPELVEKATLYLRIEALALPATLFFRVYSSLNTALA 120 A+ LSI+GSL+L F ++AKASPE+ EKATLYLRI A +LPA+L F VY++LN A+A Sbjct: 98 AIFLSIIGSLLLSFPQPLFSIAKASPEMTEKATLYLRILAFSLPASLNFLVYNTLNNAMA 157 Query: 121 RPKMVMALQLGGLLLKLPLNALLIFGGLGLPAFGGPGCAIATTLIAWLMMIAAWLLVARL 180 RPKMVMA+Q+ GLLLK+PLN L IFGG G+PAFGGPGCAIAT +I WL ++ WL++ Sbjct: 158 RPKMVMAIQVTGLLLKIPLNTLFIFGGWGIPAFGGPGCAIATFIIVWLELLIGWLILRYN 217 Query: 181 PLYRPLKLFGSGFVAPSWKSQRTLLLLGIPIGMSYFIEVTAFTLMAVFIARLGAVPVAGH 240 P YR L LFG+GF P+WKS + LL LGIP+G++YFIEVT+FT MA+FIAR+G VAGH Sbjct: 218 PFYRILHLFGTGFAWPNWKSLKELLSLGIPVGLNYFIEVTSFTFMALFIARIGVNAVAGH 277 Query: 241 QIAANVGTVLYMLPLSIASATSTLVAQAIGGGNMAEAKKIGRAGIRLAVSLSVVIGVIVW 300 QI AN VLYMLPLS+ASATSTLVAQ+IGG + A+KI AGIRL+ L++++ VW Sbjct: 278 QIVANFSGVLYMLPLSLASATSTLVAQSIGGRRLEIARKISFAGIRLSAILAIIVACAVW 337 Query: 301 FLREHIIRAYTPDPVIVGAALPLFLYIAFYQLFDSMQVTTAFVLRAYKVAVVPTVIYAVT 360 ++ II YT + + A PLFL++ FD++QVT ++VLRAYKV + PT++Y +T Sbjct: 338 LGKDWIISLYTSNETVAANAAPLFLFLCSLLFFDAIQVTASYVLRAYKVVLAPTLLYVMT 397 Query: 361 LWGVGLGGGYLLGLDPL-GMAPAALHGPVGFWAANSVSLGLVAVGLLAYLRVIQQRA 416 LW +GLG GY+ + P + G GFW +N VSL +++VG++ +R +++A Sbjct: 398 LWCIGLGCGYMFAFNFFPDYIPPRITGSSGFWFSNCVSLVILSVGMIIIMRKTEKKA 454 >ref|ZP_04576134.1| MATE efflux family protein [Oxalobacter formigenes HOxBLS] gb|EEO27096.1| MATE efflux family protein [Oxalobacter formigenes HOxBLS] Length = 466 Score = 398 bits (1023), Expect = e-109, Method: Composition-based stats. Identities = 223/419 (53%), Positives = 310/419 (73%), Gaps = 1/419 (0%) Query: 1 MVSRFSALDLGALALGVSIYVSVFVGLSGVLQALQPTIGQLYGAGRVGEIGNEVKQGMWL 60 MVSR+S DLGALA+G S+Y+SV+V L+GV+Q+L PT GQLYGAG+ E+G E KQG+WL Sbjct: 38 MVSRYSVTDLGALAVGASVYISVYVALNGVMQSLAPTFGQLYGAGKFAEMGKEAKQGVWL 97 Query: 61 AVLLSIVGSLILMFSPLFLAVAKASPELVEKATLYLRIEALALPATLFFRVYSSLNTALA 120 A+ LS+ GS +L F L++A A+PE+ EKAT YLRI A +LPA+L F VY++LN A+A Sbjct: 98 AIFLSLAGSCLLYFPQPLLSIADATPEVTEKATFYLRILAFSLPASLNFLVYTTLNNAMA 157 Query: 121 RPKMVMALQLGGLLLKLPLNALLIFGGLGLPAFGGPGCAIATTLIAWLMMIAAWLLVARL 180 RPKMVMA+Q+ GLLLK+PLN L IFGG+G+PAFGGPGCA+AT +I WL ++ +L++ Sbjct: 158 RPKMVMAIQVAGLLLKIPLNTLFIFGGMGIPAFGGPGCALATFVIVWLELLIGYLILRYN 217 Query: 181 PLYRPLKLFGSGFVAPSWKSQRTLLLLGIPIGMSYFIEVTAFTLMAVFIARLGAVPVAGH 240 P YR + LFG+G P WKS + LL LGIP+G++YFIEVT+FT MA+FIARLG VAGH Sbjct: 218 PFYRIVHLFGNGIAGPDWKSLKALLALGIPVGLNYFIEVTSFTFMALFIARLGINAVAGH 277 Query: 241 QIAANVGTVLYMLPLSIASATSTLVAQAIGGGNMAEAKKIGRAGIRLAVSLSVVIGVIVW 300 QI AN VLYMLPLS+ASATSTLVAQ+IG G + A+ I +GIRL+ +L+++ VW Sbjct: 278 QIVANFSGVLYMLPLSLASATSTLVAQSIGAGQLERARDISSSGIRLSAALALLAACSVW 337 Query: 301 FLREHIIRAYTPDPVIVGAALPLFLYIAFYQLFDSMQVTTAFVLRAYKVAVVPTVIYAVT 360 ++ II YT PV+ +A PLFL++ FD++QV++++VLRAYKV + PT++Y +T Sbjct: 338 LAKDWIISLYTAIPVVAASASPLFLFLCSLLFFDAIQVSSSYVLRAYKVVLAPTLLYVLT 397 Query: 361 LWGVGLGGGYLLGLDPL-GMAPAALHGPVGFWAANSVSLGLVAVGLLAYLRVIQQRAAR 418 LW +GLG GY + + + P+ + G GFW +N +SL ++++G+ L+ +++ + Sbjct: 398 LWCIGLGCGYAFAFNLIPSLIPSRITGSSGFWFSNCISLVILSIGMSVLLKKTEKKVRK 456 >ref|ZP_02362578.1| multidrug resistance protein NorM, putative [Burkholderia oklahomensis C6786] Length = 451 Score = 372 bits (955), Expect = e-101, Method: Composition-based stats. Identities = 235/419 (56%), Positives = 303/419 (72%), Gaps = 1/419 (0%) Query: 1 MVSRFSALDLGALALGVSIYVSVFVGLSGVLQALQPTIGQLYGAGRVGEIGNEVKQGMWL 60 MV RFSALDL AL LG SIY+SV++GL+G+L ALQP GQLYGA R EIG EV+Q MWL Sbjct: 32 MVGRFSALDLAALGLGTSIYISVYIGLTGILSALQPITGQLYGARRYAEIGEEVRQAMWL 91 Query: 61 AVLLSIVGSLILMFSPLFLAVAKASPELVEKATLYLRIEALALPATLFFRVYSSLNTALA 120 AVLL++ G L+L F L +A A EL E+ YLRI + LPA+L FR+Y++L A Sbjct: 92 AVLLAVPGFLLLHFPQPLLQIAHAPAELHERTVAYLRILSFGLPASLLFRIYNALTNAAG 151 Query: 121 RPKMVMALQLGGLLLKLPLNALLIFGGLGLPAFGGPGCAIATTLIAWLMMIAAWLLVARL 180 +P++ M+LQ+G L +K+PLN IFGGLG+PA GGPGC +A+TLI W + I + L+A+L Sbjct: 152 KPRLAMSLQIGALAVKVPLNIWFIFGGLGVPALGGPGCGLASTLINWALAIVGFTLLAKL 211 Query: 181 PLYRPLKLFGSGFVAPSWKSQRTLLLLGIPIGMSYFIEVTAFTLMAVFIARLGAVPVAGH 240 ++ PL +F S F P W+ Q+ LL LG+P+G+SY IEVT++T MA+FIA+ G +AGH Sbjct: 212 DVFEPLAIF-SRFTRPVWQRQKALLTLGVPMGLSYLIEVTSYTFMALFIAQFGTTTLAGH 270 Query: 241 QIAANVGTVLYMLPLSIASATSTLVAQAIGGGNMAEAKKIGRAGIRLAVSLSVVIGVIVW 300 QIA+NVG VLYM+PLSI A+STLVA+A+G + EA+ +GR GI LA + + V G++V+ Sbjct: 271 QIASNVGAVLYMMPLSIGVASSTLVARALGAKRLDEARALGRHGIALACAAACVYGIVVF 330 Query: 301 FLREHIIRAYTPDPVIVGAALPLFLYIAFYQLFDSMQVTTAFVLRAYKVAVVPTVIYAVT 360 LR I+ YTP+P +V AA+PL + FY FD++Q+TTAFVLRA+KVAVVPT IYAV Sbjct: 331 ALRPLIVSGYTPNPAVVAAAMPLVAIVTFYHFFDALQITTAFVLRAHKVAVVPTAIYAVA 390 Query: 361 LWGVGLGGGYLLGLDPLGMAPAALHGPVGFWAANSVSLGLVAVGLLAYLRVIQQRAARG 419 LWGVGLGGGYLLG D G+ PA L G GFW AN+ SL L GL YLR I +R G Sbjct: 391 LWGVGLGGGYLLGFDVGGVVPAPLTGARGFWIANTASLILAGGGLALYLRRIGRRELSG 449 >ref|ZP_02355435.1| multidrug resistance protein NorM, putative [Burkholderia oklahomensis EO147] Length = 451 Score = 371 bits (953), Expect = e-100, Method: Composition-based stats. Identities = 235/419 (56%), Positives = 302/419 (72%), Gaps = 1/419 (0%) Query: 1 MVSRFSALDLGALALGVSIYVSVFVGLSGVLQALQPTIGQLYGAGRVGEIGNEVKQGMWL 60 MV RFSALDL AL LG SIY+SV++GL+G+L ALQP GQLYGA R EIG EV+Q MWL Sbjct: 32 MVGRFSALDLAALGLGTSIYISVYIGLTGILSALQPITGQLYGARRYAEIGEEVRQAMWL 91 Query: 61 AVLLSIVGSLILMFSPLFLAVAKASPELVEKATLYLRIEALALPATLFFRVYSSLNTALA 120 AVLL++ G L+L F L +A A EL E+ YLRI + LPA+L FR+Y++L A Sbjct: 92 AVLLAVPGFLLLHFPQPLLQIAHAPAELHERTAAYLRILSFGLPASLLFRIYNALTNAAG 151 Query: 121 RPKMVMALQLGGLLLKLPLNALLIFGGLGLPAFGGPGCAIATTLIAWLMMIAAWLLVARL 180 +P++ M+LQ+G L +K+PLN IFGGLG+PA GGPGC +A+TLI W + I + L+A+L Sbjct: 152 KPRLAMSLQIGALAVKVPLNIWFIFGGLGVPALGGPGCGLASTLINWALAIVGFTLLAKL 211 Query: 181 PLYRPLKLFGSGFVAPSWKSQRTLLLLGIPIGMSYFIEVTAFTLMAVFIARLGAVPVAGH 240 ++ PL +F S F P W+ Q+ LL LG+P+G+SY IEVT++T MA+FIA+ G +AGH Sbjct: 212 DVFEPLAIF-SRFTRPVWQRQKALLTLGVPMGLSYLIEVTSYTFMALFIAQFGTTTLAGH 270 Query: 241 QIAANVGTVLYMLPLSIASATSTLVAQAIGGGNMAEAKKIGRAGIRLAVSLSVVIGVIVW 300 QIA+NVG VLYM PLSI A+STLVA+A+G + EA+ +GR GI LA + + V G++V+ Sbjct: 271 QIASNVGAVLYMTPLSIGVASSTLVARALGAKRLDEARALGRHGIALACAAACVYGIVVF 330 Query: 301 FLREHIIRAYTPDPVIVGAALPLFLYIAFYQLFDSMQVTTAFVLRAYKVAVVPTVIYAVT 360 LR I+ YTP+P +V AA+PL + FY FD++Q+TTAFVLRA+KVAVVPT IYAV Sbjct: 331 ALRPLIVSGYTPNPAVVAAAMPLVAIVTFYHFFDALQITTAFVLRAHKVAVVPTAIYAVA 390 Query: 361 LWGVGLGGGYLLGLDPLGMAPAALHGPVGFWAANSVSLGLVAVGLLAYLRVIQQRAARG 419 LWGVGLGGGYLLG D G+ PA L G GFW AN+ SL L GL YLR I +R G Sbjct: 391 LWGVGLGGGYLLGFDVGGVVPAPLTGARGFWIANTASLILAGGGLALYLRRIGRRELTG 449