BLASTP 2.2.17 [Aug-26-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= 0001.2415.p (386 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003773696.1| diguanylate cyclase [Herbaspirillum seropedi... 361 9e-98 ref|YP_001758065.1| diguanylate cyclase/phosphodiesterase [Methy... 230 3e-58 ref|YP_001638478.1| diguanylate cyclase [Methylobacterium extorq... 221 1e-55 ref|YP_002961982.1| diguanylate cyclase/phosphodiesterase, GGDEF... 220 3e-55 ref|YP_003066785.1| diguanylate cyclase/phosphodiesterase [Methy... 220 3e-55 >ref|YP_003773696.1| diguanylate cyclase [Herbaspirillum seropedicae SmR1] gb|ADJ61788.1| diguanylate cyclase protein [Herbaspirillum seropedicae SmR1] Length = 696 Score = 361 bits (927), Expect = 9e-98, Method: Composition-based stats. Identities = 204/313 (65%), Positives = 239/313 (76%), Gaps = 11/313 (3%) Query: 8 HVPVQDAG-NAP----SMMKLIRADQLMALRKTVLLSMPVNMLLGLISTFVAWRADKLPI 62 H P G AP S+ +LIRADQL ALR+TVLLS+PVNM+LG I TFVAWRA L I Sbjct: 33 HTPTPQTGVQAPAAQLSLQQLIRADQLAALRQTVLLSIPVNMVLGAICTFVAWRAGHLAI 92 Query: 63 ALLWLACSGVVNVLRVLACRIPVERLAALLPWLGQGQQPDARVDPVTELNLRLHWILALI 122 ALLWLACSG+VN+LR+LACR+PV+R+AAL+ Q+ A V +LNLR+HW+LAL Sbjct: 93 ALLWLACSGMVNLLRILACRLPVQRVAALV------QRIAAPGAGVIDLNLRVHWMLALC 146 Query: 123 SGFAWAGMPWLSEGYTTPETLFYLTCVCGITAGAVTHGFAFARIPISFITPPLLSVIFCL 182 SG WAG+ L GYT P TLFYLTCVCGITAGAVTHGFA+ARIPI+FITPPLL++I L Sbjct: 147 SGLVWAGVALLCAGYTAPGTLFYLTCVCGITAGAVTHGFAYARIPIAFITPPLLAIIASL 206 Query: 183 FAFNRTPTRLALAATAVIYLAGLIRGARVGERMFARACALKNEATTASQALAVAHEDLRQ 242 TR+ALAA ++YL LIRG++V E + + A ALKNEATTASQAL VAH DL Q Sbjct: 207 VLVEPDTTRVALAAAVLLYLGALIRGSKVSEGLVSHASALKNEATTASQALEVAHRDLHQ 266 Query: 243 FAARMQYQAEHDLLTGLLDRAGFMQVATQVLVQQRERQCLMFLDLDGFKVINDAYGHEAG 302 FA RM+YQAEHDLLTGLL RAGFM A + ++ E C+MFLDLDGFKVINDAYGH+AG Sbjct: 267 FAERMRYQAEHDLLTGLLGRAGFMAAAQAMAARREEVLCMMFLDLDGFKVINDAYGHDAG 326 Query: 303 DQVLIEVARRSGG 315 DQVL+EVARR G Sbjct: 327 DQVLVEVARRLQG 339 >ref|YP_001758065.1| diguanylate cyclase/phosphodiesterase [Methylobacterium radiotolerans JCM 2831] gb|ACB27382.1| diguanylate cyclase/phosphodiesterase [Methylobacterium radiotolerans JCM 2831] Length = 675 Score = 230 bits (586), Expect = 3e-58, Method: Composition-based stats. Identities = 139/295 (47%), Positives = 175/295 (59%), Gaps = 6/295 (2%) Query: 18 PSMMKLIRADQLMALRKTVLLSMPVNMLLGLISTFVAWRADKLPIALLWLACSGVVNVLR 77 P LIR DQL A+R +VL ++PVNMLLGL S VA+R+ + +W A S VN+LR Sbjct: 25 PRWNALIRRDQLDAMRGSVLAAIPVNMLLGLASILVAYRSGHGTVGAVWFAASTSVNLLR 84 Query: 78 VLACRIPVERLAALLPWLGQGQQPDARVDPVTELNLRLHWILALISGFAWAGMPWLSEGY 137 + CRIP LA AR + +LR A +SG WA P L +GY Sbjct: 85 IALCRIPCLGLALTADMTPSLAAAAARS---VDRHLRACTFAAFLSGLVWACQPLLCDGY 141 Query: 138 TTPETLFYLTCVCGITAGAVTHGFAFARIPISFITPPLLSVIFCLFAFNRTPTRLALAAT 197 TT ETLFYLT CG+TAGAVTHG A+ARIP++FI PLLSV CL A+ R LAA Sbjct: 142 TTAETLFYLTITCGVTAGAVTHGTAYARIPLAFIALPLLSVTACL-AYAGDFDRNCLAAC 200 Query: 198 AVIYLAGLIRGARVGERMFARACALKNEATTASQALAVAHEDLRQFAARMQYQAEHDLLT 257 ++Y L A E +F A LKNEA +++ A AH M+++A HD LT Sbjct: 201 VLLYFLALTHTAFRSEAVFRDASRLKNEAHALARSRAEAHASASALVDEMRWRATHDDLT 260 Query: 258 GLLDRAGFMQVATQVLVQQRERQCLMFLDLDGFKVINDAYGHEAGDQVLIEVARR 312 GLL+RAGF+Q L + L+ LDLDGFK +ND YGH+AGD+VL+EVARR Sbjct: 261 GLLNRAGFLQATENRL--RTGTLSLLMLDLDGFKFVNDVYGHKAGDRVLVEVARR 313 >ref|YP_001638478.1| diguanylate cyclase [Methylobacterium extorquens PA1] gb|ABY29407.1| diguanylate cyclase [Methylobacterium extorquens PA1] Length = 697 Score = 221 bits (564), Expect = 1e-55, Method: Composition-based stats. Identities = 144/300 (48%), Positives = 181/300 (60%), Gaps = 15/300 (5%) Query: 18 PSMMKLIRADQLMALRKTVLLSMPVNMLLGLISTFVAWRADKLPIALLWLACSGVVNVLR 77 P + +LIR DQL A+R +V ++PVN+LLGL VA + + LW + S N LR Sbjct: 38 PHLDRLIRRDQLEAVRASVQQALPVNVLLGLAGFLVALHSGHGALGALWFSASTAFNGLR 97 Query: 78 VLACRIPVERLAALLPWLGQGQQPDARVDPVTELN--LRLHWILALISGFAWAGMPWLSE 135 CR P LA + G+ P + ++ L L + AL+SG WA +P L + Sbjct: 98 FGLCRAPCAGLA-----MSPGRAPISEEAAARSIDRHLWLACLAALLSGSVWALLPLLCD 152 Query: 136 GYTTPETLFYLTCVCGITAGAVTHGFAFARIPISFITPPLLSVIFCLFA---FNRTPTRL 192 GYT+ +TLFYLT CGITAGAVTHG A+ARIPI FITPPL+SV CL A F++T Sbjct: 153 GYTSAQTLFYLTVTCGITAGAVTHGIAYARIPICFITPPLVSVAGCLLAVGGFDQT---- 208 Query: 193 ALAATAVIYLAGLIRGARVGERMFARACALKNEATTASQALAVAHEDLRQFAARMQYQAE 252 LAAT ++YLA LIR + ER F LKNEAT ++A AH A M+ +A Sbjct: 209 CLAATVLLYLAALIRSSIATERGFRETSRLKNEATALAEARKAAHASASALAEEMRERAT 268 Query: 253 HDLLTGLLDRAGFMQVATQVLVQQRERQCLMFLDLDGFKVINDAYGHEAGDQVLIEVARR 312 HD LTGLL+RAGF+Q A + L CLM LDLDGFK +ND YGH GD+VL EVARR Sbjct: 269 HDGLTGLLNRAGFIQRAEEQLAAGAS-VCLMLLDLDGFKSVNDVYGHSTGDRVLAEVARR 327 >ref|YP_002961982.1| diguanylate cyclase/phosphodiesterase, GGDEF and EAL domains [methylobacterium extorquens AM1] gb|ACS38705.1| putative diguanylate cyclase/phosphodiesterase, GGDEF and EAL domains [Methylobacterium extorquens AM1] Length = 668 Score = 220 bits (561), Expect = 3e-55, Method: Composition-based stats. Identities = 144/300 (48%), Positives = 181/300 (60%), Gaps = 15/300 (5%) Query: 18 PSMMKLIRADQLMALRKTVLLSMPVNMLLGLISTFVAWRADKLPIALLWLACSGVVNVLR 77 P + +LIR DQL A+R +V ++PVN+LLGL VA + + LW + S N LR Sbjct: 9 PHLDRLIRRDQLEAVRASVQQALPVNVLLGLAGFLVALHSGHGALGALWFSASTAFNGLR 68 Query: 78 VLACRIPVERLAALLPWLGQGQQPDARVDPVTELN--LRLHWILALISGFAWAGMPWLSE 135 CR P LA + G+ P + ++ L L + AL+SG WA +P L + Sbjct: 69 FGLCRAPCAGLA-----MSPGRAPISEEAAARSIDRHLWLACLAALLSGSVWALLPLLCD 123 Query: 136 GYTTPETLFYLTCVCGITAGAVTHGFAFARIPISFITPPLLSVIFCLFA---FNRTPTRL 192 GYT+ +TLFYLT CGITAGAVTHG A+ARIPI FITPPL+SV CL A F++T Sbjct: 124 GYTSAQTLFYLTVTCGITAGAVTHGIAYARIPICFITPPLVSVAGCLLAVGGFDQT---- 179 Query: 193 ALAATAVIYLAGLIRGARVGERMFARACALKNEATTASQALAVAHEDLRQFAARMQYQAE 252 LAAT ++YLA LIR + ER F LKNEAT ++A AH A M+ +A Sbjct: 180 CLAATVLLYLAALIRSSIATERGFRETSRLKNEATALAEARKAAHASASALAEEMRERAT 239 Query: 253 HDLLTGLLDRAGFMQVATQVLVQQRERQCLMFLDLDGFKVINDAYGHEAGDQVLIEVARR 312 HD LTGLL+RAGF+Q A + L CLM LDLDGFK +ND YGH GD+VL EVARR Sbjct: 240 HDGLTGLLNRAGFIQRAEEQLAAGAS-VCLMLLDLDGFKSVNDVYGHSTGDRVLAEVARR 298 >ref|YP_003066785.1| diguanylate cyclase/phosphodiesterase [Methylobacterium extorquens DM4] emb|CAX22768.1| putative diguanylate cyclase/phosphodiesterase, GGDEF and EAL domains [Methylobacterium extorquens DM4] Length = 668 Score = 220 bits (561), Expect = 3e-55, Method: Composition-based stats. Identities = 144/300 (48%), Positives = 181/300 (60%), Gaps = 15/300 (5%) Query: 18 PSMMKLIRADQLMALRKTVLLSMPVNMLLGLISTFVAWRADKLPIALLWLACSGVVNVLR 77 P + +LIR DQL A+R +V ++PVN+LLGL VA + + LW + S N LR Sbjct: 9 PHLDRLIRRDQLEAVRASVQQALPVNVLLGLAGFLVALHSGHGALGALWFSASTAFNGLR 68 Query: 78 VLACRIPVERLAALLPWLGQGQQPDARVDPVTELN--LRLHWILALISGFAWAGMPWLSE 135 CR P LA + G+ P + ++ L L + AL+SG WA +P L + Sbjct: 69 FGLCRAPCAGLA-----MSPGRAPISEEAAARSIDRHLWLACLAALLSGSVWALLPLLCD 123 Query: 136 GYTTPETLFYLTCVCGITAGAVTHGFAFARIPISFITPPLLSVIFCLFA---FNRTPTRL 192 GYT+ +TLFYLT CGITAGAVTHG A+ARIPI FITPPL+SV CL A F++T Sbjct: 124 GYTSAQTLFYLTVTCGITAGAVTHGIAYARIPICFITPPLVSVAGCLLAVGGFDQT---- 179 Query: 193 ALAATAVIYLAGLIRGARVGERMFARACALKNEATTASQALAVAHEDLRQFAARMQYQAE 252 LAAT ++YLA LIR + ER F LKNEAT ++A AH A M+ +A Sbjct: 180 CLAATVLLYLAALIRSSIATERGFRETSRLKNEATALAEARKAAHASASALAEEMRERAT 239 Query: 253 HDLLTGLLDRAGFMQVATQVLVQQRERQCLMFLDLDGFKVINDAYGHEAGDQVLIEVARR 312 HD LTGLL+RAGF+Q A + L CLM LDLDGFK +ND YGH GD+VL EVARR Sbjct: 240 HDGLTGLLNRAGFIQRAEEQLAAGAS-VCLMLLDLDGFKSVNDVYGHSTGDRVLAEVARR 298