BLASTP 2.2.17 [Aug-26-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= 0001.2379.p (324 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|ZP_08782558.1| diguanylate cyclase [Methylobacter tundripalu... 328 6e-88 ref|YP_003847994.1| diguanylate cyclase with PAS/PAC sensor [Gal... 258 1e-66 ref|YP_523144.1| diguanylate cyclase [Rhodoferax ferrireducens T... 236 4e-60 gb|EGW60081.1| diguanylate cyclase with PAS/PAC sensor [Dechloro... 216 6e-54 ref|ZP_08822415.1| diguanylate cyclase with PAS/PAC sensor [Thio... 192 5e-47 >ref|ZP_08782558.1| diguanylate cyclase [Methylobacter tundripaludum SV96] gb|EGW20830.1| diguanylate cyclase [Methylobacter tundripaludum SV96] Length = 325 Score = 328 bits (842), Expect = 6e-88, Method: Composition-based stats. Identities = 166/321 (51%), Positives = 217/321 (67%), Gaps = 9/321 (2%) Query: 1 MSTAVVPRFRAEDVLDQLHGGLIMLDAGLHILLWNAWVARHSRVPADQALDARFEHVFDE 60 M+T RF ED+ + L+ G+ ++DA +LLWN W+A+HS + AL+ +FE+VF E Sbjct: 1 MNTLSAKRFDMEDIFNSLNLGVCVVDADSKVLLWNNWIAKHSDIKETDALNRQFENVFSE 60 Query: 61 RVSPALLRAIDNTLGYGLPAVLSSALHRAPLPLYPDHGAAQAAGALAAPARMVQSVVLTP 120 VSPA L A+ NTL + LP VLS+ALHR PLPLY A Q RM QS+ +TP Sbjct: 61 SVSPAFLTALKNTLTHRLPVVLSTALHRTPLPLYNGCEANQQQ------TRMYQSITITP 114 Query: 121 LDSPEGERLCLIQISDASNSVRREKMLRSHSEALKRQAGTDGLTGIHNRRHFDEHYAQAL 180 + S E CLIQI+D+S S++REKMLRSHSE LK++A TD LT I NRR FD HY A+ Sbjct: 115 IQSQLNESCCLIQITDSSTSIKREKMLRSHSEILKKEATTDSLTDICNRRFFDAHYEMAV 174 Query: 181 QRAKGAGGTLSLFMVDVDFFKQYNDHYGHGPGDQVLKRVAAALQGQLQRPGDLLARYGGE 240 AK LS+FMVD+DFFK YND+YGH GD +K+VA+AL+ QL R D++ARYGGE Sbjct: 175 AEAKRQKHPLSIFMVDIDFFKSYNDYYGHIAGDNAIKQVASALKSQLSRATDIVARYGGE 234 Query: 241 EFILLMEGLSPRQAAEVAEALRETVYALAEPHAKSLVAHRVTISVGVCTRAVQEGMDGRL 300 EF+L+M L + A + AE LR V+ LA PH KS +++TISVG+CT + E D Sbjct: 235 EFVLVMPHLPQKVAEQFAEKLRSAVFNLAMPHIKSRPFNQITISVGLCT-GIPENDDN-- 291 Query: 301 LMSAADAALYRAKLGGRNKVV 321 L++ ADAALY+AKL GRN+ + Sbjct: 292 LLNKADAALYQAKLKGRNRCI 312 >ref|YP_003847994.1| diguanylate cyclase with PAS/PAC sensor [Gallionella capsiferriformans ES-2] gb|ADL56230.1| diguanylate cyclase with PAS/PAC sensor [Gallionella capsiferriformans ES-2] Length = 337 Score = 258 bits (658), Expect = 1e-66, Method: Composition-based stats. Identities = 133/298 (44%), Positives = 179/298 (60%), Gaps = 5/298 (1%) Query: 21 GLIMLDAGLHILLWNAWVARHSRVPADQALDARFEHVFDERVSPALLRAIDNTLGYGLPA 80 GLI++D +++WN WV+ HS + QA+ E +F + + + A+ N L Y LP Sbjct: 22 GLILIDNQGVVVIWNDWVSEHSGITEKQAVGQTLESLFTDGLGASFKTAMQNALTYKLPV 81 Query: 81 VLSSALHRAPLPLYPDHGAAQAAGALAAPARMVQSVVLTPLDSPEGERLCLIQISDASNS 140 VLSS LHR+PLPLYP Q AR+ QSV LTP+ +P+G CLIQI+D S S Sbjct: 82 VLSSVLHRSPLPLYPLPCTRQKQ-----QARIHQSVSLTPIITPDGAHQCLIQITDTSVS 136 Query: 141 VRREKMLRSHSEALKRQAGTDGLTGIHNRRHFDEHYAQALQRAKGAGGTLSLFMVDVDFF 200 RE ML+SHS+ L A TDGLTG +NRR+F+E + R G L+L M+D+D F Sbjct: 137 FTREHMLKSHSKQLSIDATTDGLTGAYNRRYFNERFKAEFGRVNRQGTPLALLMLDIDCF 196 Query: 201 KQYNDHYGHGPGDQVLKRVAAALQGQLQRPGDLLARYGGEEFILLMEGLSPRQAAEVAEA 260 K YND YGH GD+VL R+ ++ QL R D++ RYGGEEF +L+ A VA+ Sbjct: 197 KDYNDFYGHPAGDRVLIRIVERIKSQLNRTTDVVTRYGGEEFAILLPDCELEGARAVAQK 256 Query: 261 LRETVYALAEPHAKSLVAHRVTISVGVCTRAVQEGMDGRLLMSAADAALYRAKLGGRN 318 ++ + L PHAKS VA VT+S+G+ T +V D L++ AD ALY AK GRN Sbjct: 257 IQHAILTLNIPHAKSNVADHVTLSIGIATHSVNSSCDANFLLNTADTALYTAKHEGRN 314 >ref|YP_523144.1| diguanylate cyclase [Rhodoferax ferrireducens T118] gb|ABD69613.1| diguanylate cyclase [Rhodoferax ferrireducens T118] Length = 327 Score = 236 bits (602), Expect = 4e-60, Method: Composition-based stats. Identities = 143/307 (46%), Positives = 184/307 (59%), Gaps = 6/307 (1%) Query: 14 VLDQLHGGLIMLDAGLHILLWNAWVARHSRVPADQALDARFEHVFDERVSPALLRAIDNT 73 +LD + GL+++DA +LLWNAW+ARHS V A A VF +S + L A+ NT Sbjct: 15 ILDAVELGLVLVDADARVLLWNAWLARHSGVSAQTARGQPLAGVFGAGLSASFLTALSNT 74 Query: 74 LGYGLPAVLSSALHRAPLPLYPDHGAAQAAGALAAPARMVQSVVLTPLDSPEGERLCLIQ 133 L Y LP VLS+ LH PLPLY AQ A AA ARM ++ +TPL P CLIQ Sbjct: 75 LRYRLPVVLSNVLHFCPLPLY-----AQTP-ADAAAARMPHAITMTPLVLPPWGACCLIQ 128 Query: 134 ISDASNSVRREKMLRSHSEALKRQAGTDGLTGIHNRRHFDEHYAQALQRAKGAGGTLSLF 193 I+D+S ++ REK+L+ SE L R+ TD LT +R FD Y Q RA+ G LSL Sbjct: 129 ITDSSRAISREKVLQRQSERLNREVMTDSLTRAFSRGFFDHFYQQEFARAQRKGTKLSLI 188 Query: 194 MVDVDFFKQYNDHYGHGPGDQVLKRVAAALQGQLQRPGDLLARYGGEEFILLMEGLSPRQ 253 M+DVD+FK YND YGH GD+VL V ALQ L R D LARYGGEEF +++ + Sbjct: 189 MIDVDYFKDYNDAYGHPAGDKVLIAVVQALQAVLLRSTDKLARYGGEEFAVILPDCGEHK 248 Query: 254 AAEVAEALRETVYALAEPHAKSLVAHRVTISVGVCTRAVQEGMDGRLLMSAADAALYRAK 313 A +AE LR V AL PH KS +++++T+S+G T + + L+ AAD ALY AK Sbjct: 249 ALAIAELLRTAVLALNLPHRKSAISNQLTVSLGTSTLKAGQTSSAQALLDAADQALYAAK 308 Query: 314 LGGRNKV 320 GRN V Sbjct: 309 NQGRNCV 315 >gb|EGW60081.1| diguanylate cyclase with PAS/PAC sensor [Dechlorosoma suillum PS] Length = 328 Score = 216 bits (549), Expect = 6e-54, Method: Composition-based stats. Identities = 127/307 (41%), Positives = 177/307 (57%), Gaps = 8/307 (2%) Query: 18 LHGGLIMLDAGLHILLWNAWVARHSRVPADQALDARFEHVFDERVSPALLRAIDNTLGYG 77 ++ GLI++DA + LWN W+A S V A + R E VF + L A+ L Sbjct: 18 VNAGLILIDAEGKVQLWNRWLAERSGVSAQEIQGRRLEEVFPHLANSRLAHAVQTALQQQ 77 Query: 78 LPAVLSSALHRAPLPLYPDHGAAQAAGALAAPARMVQSVVLTPLDSPEGERLCLIQISDA 137 LPA+LS L+R P PL DH A + Q++ + PL G CLIQI D Sbjct: 78 LPAILSQTLNRRPFPL-QDHLHNDAH-------PIEQAITIAPLARESGHIHCLIQIQDV 129 Query: 138 SNSVRREKMLRSHSEALKRQAGTDGLTGIHNRRHFDEHYAQALQRAKGAGGTLSLFMVDV 197 + +VRRE+ LR ++ L+ + DGLTG+ NRR FD + + QRA+ G +S+ M+D+ Sbjct: 130 TAAVRREQQLREQAQQLQALSNIDGLTGVANRRSFDARFQEEFQRAQRHGSDISVLMLDI 189 Query: 198 DFFKQYNDHYGHGPGDQVLKRVAAALQGQLQRPGDLLARYGGEEFILLMEGLSPRQAAEV 257 D+FK+YND YGH GD L VA L+ LQR GD +ARYGGEEF +++ G S A ++ Sbjct: 190 DYFKEYNDCYGHQAGDTCLTVVANTLRRCLQRGGDFVARYGGEEFAVVLPGASHGAACKL 249 Query: 258 AEALRETVYALAEPHAKSLVAHRVTISVGVCTRAVQEGMDGRLLMSAADAALYRAKLGGR 317 A +L++ + L PHA S A ++ISVGV T Q + L+ AD ALY+AK GR Sbjct: 250 ASSLQQEISRLGIPHANSHAASHLSISVGVATHTPQRNDRAQDLLRGADIALYQAKRQGR 309 Query: 318 NKVVATD 324 N+VV+ D Sbjct: 310 NRVVSAD 316 >ref|ZP_08822415.1| diguanylate cyclase with PAS/PAC sensor [Thiorhodococcus drewsii AZ1] gb|EGV32379.1| diguanylate cyclase with PAS/PAC sensor [Thiorhodococcus drewsii AZ1] Length = 321 Score = 192 bits (489), Expect = 5e-47, Method: Composition-based stats. Identities = 122/311 (39%), Positives = 168/311 (54%), Gaps = 8/311 (2%) Query: 14 VLDQLHGGLIMLDAGLHILLWNAWVARHSRVPADQALDARFEHVFDERVSPALLRAIDNT 73 ++DQL G+++LD +L WNAW+ RHS + + E VF E LL I Sbjct: 9 LMDQLQTGVVLLDDRGCLLSWNAWMTRHSGIAPEDVAGRPIEDVFVEMKHSRLLNCIQQA 68 Query: 74 LGYGLPAVLSSALHRAPLPLYPDHGAAQAAGALAAPARMVQSVVLTPLDSPEGERLCLIQ 133 L + L +VL+ L+ + LPLY Q G RM Q V +TP S CLIQ Sbjct: 69 LRFRLSSVLTPGLNPSVLPLY------QKPGDRELDQRMQQLVYVTPTCS--DPYACLIQ 120 Query: 134 ISDASNSVRREKMLRSHSEALKRQAGTDGLTGIHNRRHFDEHYAQALQRAKGAGGTLSLF 193 I D + +VRRE+ LR+ S L D LTG+ NRR FD+ ++ + A+ ++L Sbjct: 121 IQDMTATVRRERRLRAQSSQLIATTYRDSLTGVGNRRRFDQDLSERFREARSRQIHIALL 180 Query: 194 MVDVDFFKQYNDHYGHGPGDQVLKRVAAALQGQLQRPGDLLARYGGEEFILLMEGLSPRQ 253 M+DVD FK +ND +GH GD+ L VA+ALQ L++ GD ++RYGGEEF L + G Sbjct: 181 MIDVDDFKAFNDRFGHQKGDEALIMVASALQEGLRQEGDCISRYGGEEFALTLLGADQEA 240 Query: 254 AAEVAEALRETVYALAEPHAKSLVAHRVTISVGVCTRAVQEGMDGRLLMSAADAALYRAK 313 A+ VAE LR V L H S A VT+S+G+ + + L+S AD ALY AK Sbjct: 241 ASTVAERLRLRVEGLRLLHPTSRTARHVTVSIGISAVVPSMELPPQTLVSQADLALYSAK 300 Query: 314 LGGRNKVVATD 324 GRN+ + D Sbjct: 301 DRGRNRCMCFD 311