BLASTP 2.2.17 [Aug-26-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= 0001.2371.p (276 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003775371.1| cobalamin-5-phosphate synthase [Herbaspirill... 345 5e-93 ref|YP_001099265.1| putative cobalamin synthase [Herminiimonas a... 297 1e-78 ref|YP_001352778.1| cobalamin (5'-phosphate) synthase [Janthinob... 264 1e-68 ref|YP_003168259.1| cobalamin synthase [Candidatus Accumulibacte... 211 1e-52 ref|YP_283378.1| cobalamin synthase [Dechloromonas aromatica RCB... 209 4e-52 >ref|YP_003775371.1| cobalamin-5-phosphate synthase [Herbaspirillum seropedicae SmR1] gb|ADJ63463.1| cobalamin-5-phosphate synthase protein [Herbaspirillum seropedicae SmR1] Length = 274 Score = 345 bits (885), Expect = 5e-93, Method: Composition-based stats. Identities = 212/265 (80%), Positives = 229/265 (86%) Query: 7 TSPPPPRNDGPLYQLRLFFTALQFFTRLPIPRWVGFQPHWLQHATRYFPLVGWIVAWACA 66 TS P G LYQLRLFFTALQFFTRLPIPRWVGF P WL H+TRYFPLVGWIVAWA A Sbjct: 5 TSSPSAPGRGLLYQLRLFFTALQFFTRLPIPRWVGFHPDWLAHSTRYFPLVGWIVAWATA 64 Query: 67 LVYLLAVQFWPQMVAVLLSTAAGIWLTGAFHEDGFADVCDGLGGAVNRERALEIMRDSRL 126 LVYLLAVQFWPQ VAVLL TAAGIWLTGAFHEDGFAD+CDGLGGAV+RERALEIMRDSRL Sbjct: 65 LVYLLAVQFWPQPVAVLLGTAAGIWLTGAFHEDGFADLCDGLGGAVSRERALEIMRDSRL 124 Query: 127 GSYGVIGIVALLLAKLAALQALLPLQVLAVLGMAHPLSRWLATCLIWRMEYVREEGKVKP 186 GSYGVIG+V L+L +LAAL AL P Q+LA LG+AHPLSRWLATCLIWRM+YVREEGK K Sbjct: 125 GSYGVIGLVLLMLTRLAALAALQPWQILAALGIAHPLSRWLATCLIWRMDYVREEGKSKL 184 Query: 187 LAQQMGQGEFLLATFFAVLPVIGVIALGMMSWQRIAAGVLLAAVATLWLAARFRRRLGGY 246 LAQ+M GEFL+AT + V+PVIG +ALG+MSWQ IA G LAA+A LWLA R +RRLGGY Sbjct: 185 LAQRMSTGEFLVATVWVVVPVIGTVALGLMSWQHIAMGCGLAALAALWLAYRLQRRLGGY 244 Query: 247 TGDCLGAVQQLSETAFYLGALASLP 271 TGD LGAVQQLSET FYLG LASLP Sbjct: 245 TGDGLGAVQQLSETVFYLGVLASLP 269 >ref|YP_001099265.1| putative cobalamin synthase [Herminiimonas arsenicoxydans] emb|CAL61138.1| putative cobalamin synthase cobS [Herminiimonas arsenicoxydans] Length = 270 Score = 297 bits (761), Expect = 1e-78, Method: Composition-based stats. Identities = 156/255 (61%), Positives = 187/255 (73%) Query: 18 LYQLRLFFTALQFFTRLPIPRWVGFQPHWLQHATRYFPLVGWIVAWACALVYLLAVQFWP 77 ++QLRLFF ALQFFTR+PIPRWVGF WLQHA+RYFP VG +VA CALVYLL FW Sbjct: 16 VHQLRLFFVALQFFTRIPIPRWVGFDERWLQHASRYFPAVGIVVALVCALVYLLGSLFWN 75 Query: 78 QMVAVLLSTAAGIWLTGAFHEDGFADVCDGLGGAVNRERALEIMRDSRLGSYGVIGIVAL 137 Q VAVLLS +AGI+LTGAFHEDGFAD CDG GG + ER LEIM DSR+G+YG IGI + Sbjct: 76 QSVAVLLSMSAGIYLTGAFHEDGFADTCDGFGGGMTEERVLEIMTDSRIGAYGAIGIGMM 135 Query: 138 LLAKLAALQALLPLQVLAVLGMAHPLSRWLATCLIWRMEYVREEGKVKPLAQQMGQGEFL 197 L K L ++ V+A L + HP SR A L+WRM YV+ GK KP+ QQM GEF Sbjct: 136 LALKWVVLSSMPSPAVVAALLIVHPFSRLAAISLVWRMNYVKANGKAKPIGQQMSNGEFC 195 Query: 198 LATFFAVLPVIGVIALGMMSWQRIAAGVLLAAVATLWLAARFRRRLGGYTGDCLGAVQQL 257 +A+ A+LP++ G M W+ IAAGVLLAA+ +LWLA F+RR+GGYTGDCLGAVQQ Sbjct: 196 IASATALLPMVLFSLTGWMPWEAIAAGVLLAAIVSLWLARMFQRRIGGYTGDCLGAVQQA 255 Query: 258 SETAFYLGALASLPF 272 +E A YLG LA+L + Sbjct: 256 AEVACYLGILAALAY 270 >ref|YP_001352778.1| cobalamin (5'-phosphate) synthase [Janthinobacterium sp. Marseille] gb|ABR89122.1| cobalamin (5'-phosphate) synthase [Janthinobacterium sp. Marseille] Length = 270 Score = 264 bits (674), Expect = 1e-68, Method: Composition-based stats. Identities = 145/250 (58%), Positives = 178/250 (71%) Query: 18 LYQLRLFFTALQFFTRLPIPRWVGFQPHWLQHATRYFPLVGWIVAWACALVYLLAVQFWP 77 L+QLRLFF ALQFFTR+P+PRWVGF WLQHA+RYFP VG +VA A +VY++A W Sbjct: 16 LHQLRLFFIALQFFTRIPVPRWVGFDVQWLQHASRYFPAVGIVVALASIVVYIIASLLWT 75 Query: 78 QMVAVLLSTAAGIWLTGAFHEDGFADVCDGLGGAVNRERALEIMRDSRLGSYGVIGIVAL 137 Q +AVLLST AGI+LTGAFHEDGFAD CDGLGG ER LEIM+DSR+G+YG IGI + Sbjct: 76 QSIAVLLSTIAGIYLTGAFHEDGFADTCDGLGGGGTPERVLEIMKDSRIGAYGAIGIGLM 135 Query: 138 LLAKLAALQALLPLQVLAVLGMAHPLSRWLATCLIWRMEYVREEGKVKPLAQQMGQGEFL 197 L K AL +L V++ L +AHPLSR A L+WRMEY + GK KP+AQQM EF Sbjct: 136 LALKWMALSSLPSPAVVSALLIAHPLSRLAAISLVWRMEYAKANGKAKPIAQQMSNREFG 195 Query: 198 LATFFAVLPVIGVIALGMMSWQRIAAGVLLAAVATLWLAARFRRRLGGYTGDCLGAVQQL 257 +A LP+ + G++ +A G+ AA+A WLA F+RR+ GYTGD LGAVQQ+ Sbjct: 196 IAAGTTFLPIALLCLTGLLPVSGVACGIFFAALAAFWLARLFQRRIAGYTGDTLGAVQQV 255 Query: 258 SETAFYLGAL 267 +E AFYLG L Sbjct: 256 AEVAFYLGVL 265 >ref|YP_003168259.1| cobalamin synthase [Candidatus Accumulibacter phosphatis clade IIA str. UW-1] gb|ACV36330.1| cobalamin 5'-phosphate synthase [Candidatus Accumulibacter phosphatis clade IIA str. UW-1] Length = 250 Score = 211 bits (536), Expect = 1e-52, Method: Composition-based stats. Identities = 127/248 (51%), Positives = 164/248 (66%), Gaps = 6/248 (2%) Query: 20 QLRLFFTALQFFTRLPIPRWVGFQPHWLQHATRYFPLVGWIVAWACALVYLLAVQFWPQM 79 ++ FF A++FFTRLP+P WVG L A RYFP VG +V ALV++L Q WP Sbjct: 5 EIEYFFGAIRFFTRLPVPAWVGHSSEALNRAARYFPAVGLLVGAIAALVFVLTAQVWPTT 64 Query: 80 VAVLLSTAAGIWLTGAFHEDGFADVCDGLGGAVNRERALEIMRDSRLGSYGVIGIVALLL 139 +AVL S ++ +++TGAFHEDG++D+ DG GG + + L IM+DSR+GS+G I +V LLL Sbjct: 65 LAVLASMSSALYVTGAFHEDGWSDMVDGFGGGWEKAQILAIMKDSRIGSFGAIALVILLL 124 Query: 140 AKLAALQALLPLQVLAVLGMAHPLSRWLATCLIWRMEYVREEGKVKPLAQQMGQGEFLLA 199 A+ AL L P V A L H +SR+ AT L+ + YVR+EGK KPLA ++G GE L A Sbjct: 125 ARFCALIELDPAVVAAALLAGHTISRFAATTLLRGLAYVRDEGKSKPLATRIGWGELLFA 184 Query: 200 TFFAVLPVIGVIALGMMSWQRIAAGVLLAAVATLWLAARFRRRLGGYTGDCLGAVQQLSE 259 AVLP++ + A + G L AA+ATLWLA F RR+GGYTGDCLGA QQLSE Sbjct: 185 GVTAVLPLLLLPATEAL------LGCLFAALATLWLARLFGRRIGGYTGDCLGATQQLSE 238 Query: 260 TAFYLGAL 267 AFY G L Sbjct: 239 VAFYCGLL 246 >ref|YP_283378.1| cobalamin synthase [Dechloromonas aromatica RCB] gb|AAZ44908.1| cobalamin-5'-phosphate synthase [Dechloromonas aromatica RCB] Length = 256 Score = 209 bits (531), Expect = 4e-52, Method: Composition-based stats. Identities = 136/259 (52%), Positives = 172/259 (66%), Gaps = 9/259 (3%) Query: 20 QLRLFFTALQFFTRLPIPRWVGFQPHWLQHATRYFPLVGWIVAWACALVYLLAVQFWPQM 79 +L FF A++FFTRLP+P WVG L H+ RYFP VG +V ALVY LA+ WPQ Sbjct: 5 ELEYFFGAIRFFTRLPVPGWVGHSAEALNHSARYFPAVGLLVGGIGALVYWLALYLWPQP 64 Query: 80 VAVLLSTAAGIWLTGAFHEDGFADVCDGLGGAVNRERALEIMRDSRLGSYGVIGIVALLL 139 VAVLLS AA I+ TGAFHEDG +D DGLGG + R L+IM+DSR+GSYGV+ +V LL Sbjct: 65 VAVLLSMAATIYATGAFHEDGLSDTVDGLGGGWEKARILDIMKDSRVGSYGVVAMVLALL 124 Query: 140 AKLAALQALLPLQVLAVLGMAHPLSRWLATCLIWRMEYVREE--GKVKPLAQQMGQGEFL 197 K L +L P V L H +SR+ AT L+ M+YVR++ K KPLA +M G + Sbjct: 125 GKFVLLSSLAPALVPFALLAGHAVSRFCATVLLATMDYVRDDQLSKAKPLANRMSAGAIV 184 Query: 198 LATFFAVLPVIGVIALGMMSWQRIAAGVLLAAVATLWLAARFRRRLGGYTGDCLGAVQQL 257 +A FAV P++ + W + AAG+ LAA+ATLWLA +F+R LGGYTGDCLGA QQ Sbjct: 185 VALCFAVAPLLA------LPWFKAAAGLALAALATLWLARKFQRWLGGYTGDCLGATQQF 238 Query: 258 SETAFYLGALASLPFWWNP 276 +E FYLG +A+L F NP Sbjct: 239 AEIVFYLGLMANL-FAQNP 256