BLASTP 2.2.17 [Aug-26-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= 0001.2257.p (297 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003775268.1| 2-dehydropantoate 2-reductase [Herbaspirillu... 437 e-121 ref|YP_001860093.1| 2-dehydropantoate 2-reductase [Burkholderia ... 386 e-105 ref|YP_002946826.1| 2-dehydropantoate 2-reductase [Variovorax pa... 382 e-104 ref|YP_004157901.1| 2-dehydropantoate 2-reductase [Variovorax pa... 375 e-102 ref|YP_549741.1| 2-dehydropantoate 2-reductase [Polaromonas sp. ... 375 e-102 >ref|YP_003775268.1| 2-dehydropantoate 2-reductase [Herbaspirillum seropedicae SmR1] gb|ADJ63360.1| 2-dehydropantoate 2-reductase protein [Herbaspirillum seropedicae SmR1] Length = 297 Score = 437 bits (1125), Expect = e-121, Method: Composition-based stats. Identities = 246/297 (82%), Positives = 270/297 (90%) Query: 1 MKVAVMGAGAVGCYFAGMLARAGHDVVLVGRPQHVEAFNTKGLRLEAKTFDETLPVEAST 60 MKVAVMGAGAVGCYFAGMLAR GH V LVGRPQHVEAFNT+GLRLE K FDET+ V+AST Sbjct: 1 MKVAVMGAGAVGCYFAGMLARVGHQVALVGRPQHVEAFNTRGLRLETKAFDETIAVKAST 60 Query: 61 DPAIVAGADLVLFCVKSPDTETAGAQLRPHLAPDTLVLTLQNGTDNAERLRTVIPQPVSA 120 D AI A A+LVLFCVKSPDTETAGAQL PHLAPDTLVL+LQNGTDNAERLRTV+ QPV+A Sbjct: 61 DAAIAADAELVLFCVKSPDTETAGAQLAPHLAPDTLVLSLQNGTDNAERLRTVMAQPVAA 120 Query: 121 AVVYVATEMAGPGHVKHHGRGELVIEPSARSQQAAEALIAAGVPTEISENVRGALWLKLI 180 AVVYVATEMAGPGHVKHHGRGELVIEP+A S+ AA+AL+AAGVPTEIS+NVRG LWLKLI Sbjct: 121 AVVYVATEMAGPGHVKHHGRGELVIEPAAGSRDAADALVAAGVPTEISDNVRGELWLKLI 180 Query: 181 INCAYNALSAITLLPYGKLVEGVGVLEVMDHLVSECKAVAAAEGVTLAGDVDVAIRKIIE 240 +NCAYNALSAI LPYGKLVEG G+ EV+ LV+ECKAVAAAEGVTLA DVD A+RKI++ Sbjct: 181 LNCAYNALSAIAQLPYGKLVEGPGIPEVIAQLVTECKAVAAAEGVTLADDVDSAVRKIVQ 240 Query: 241 TMPTQFSSTAQDVARGKPSEIDHLNGYIVRRGQAHGIATPVNLTVHALVKLIESKAR 297 TMP QFSSTAQD+ARGKPSEIDHLNG+IV R QAHG++ P NLTVHALVKLIESKA+ Sbjct: 241 TMPGQFSSTAQDLARGKPSEIDHLNGFIVARAQAHGLSAPANLTVHALVKLIESKAQ 297 >ref|YP_001860093.1| 2-dehydropantoate 2-reductase [Burkholderia phymatum STM815] gb|ACC73047.1| 2-dehydropantoate 2-reductase [Burkholderia phymatum STM815] Length = 295 Score = 386 bits (991), Expect = e-105, Method: Composition-based stats. Identities = 208/295 (70%), Positives = 246/295 (83%) Query: 1 MKVAVMGAGAVGCYFAGMLARAGHDVVLVGRPQHVEAFNTKGLRLEAKTFDETLPVEAST 60 MK+AVMGAGAVGCY+ GMLARAGHDVVLVGRPQHVEA +GLRLE + FDE +P+ AST Sbjct: 1 MKIAVMGAGAVGCYYGGMLARAGHDVVLVGRPQHVEAIEHRGLRLETQAFDERIPLAAST 60 Query: 61 DPAIVAGADLVLFCVKSPDTETAGAQLRPHLAPDTLVLTLQNGTDNAERLRTVIPQPVSA 120 + V GA+LVLFCVKS DT +A +++P L PDTLVL+LQNG +NA+ +R ++PQ V+A Sbjct: 61 QASAVQGANLVLFCVKSTDTVSAALEIKPFLLPDTLVLSLQNGVENADEVRKLVPQEVAA 120 Query: 121 AVVYVATEMAGPGHVKHHGRGELVIEPSARSQQAAEALIAAGVPTEISENVRGALWLKLI 180 AVVYVATEMAGPGHV+HHGRGELVIEPS S + A+ LIAAGVPTEIS+NVRGALW KLI Sbjct: 121 AVVYVATEMAGPGHVRHHGRGELVIEPSKASAEVAQTLIAAGVPTEISDNVRGALWAKLI 180 Query: 181 INCAYNALSAITLLPYGKLVEGVGVLEVMDHLVSECKAVAAAEGVTLAGDVDVAIRKIIE 240 +NCAYNALSAIT LPYG+LV+G GV VM +V EC AVA A+GVT+ GDV+ A+R I E Sbjct: 181 LNCAYNALSAITRLPYGRLVQGEGVTTVMRDIVDECLAVAKADGVTIPGDVNQAVRMIAE 240 Query: 241 TMPTQFSSTAQDVARGKPSEIDHLNGYIVRRGQAHGIATPVNLTVHALVKLIESK 295 TMP Q+SSTAQD++RGK SEIDHLNG IVRRG+A G+ATP N +H LVKLIES+ Sbjct: 241 TMPGQYSSTAQDLSRGKRSEIDHLNGLIVRRGEALGVATPSNHLLHTLVKLIESQ 295 >ref|YP_002946826.1| 2-dehydropantoate 2-reductase [Variovorax paradoxus S110] gb|ACS21560.1| 2-dehydropantoate 2-reductase [Variovorax paradoxus S110] Length = 298 Score = 382 bits (981), Expect = e-104, Method: Composition-based stats. Identities = 207/298 (69%), Positives = 246/298 (82%), Gaps = 1/298 (0%) Query: 1 MKVAVMGAGAVGCYFAGMLARAGHDVVLVGRPQHVEAFNTKGLRLEAKTFDETLPVEAST 60 MKVAVMGAGAVGCY+ MLARAGH+VVL+GRP HVEA +GLRLE K FDE + ++AST Sbjct: 1 MKVAVMGAGAVGCYYGAMLARAGHEVVLIGRPSHVEAVRARGLRLETKAFDEQVRLDAST 60 Query: 61 DPAIVAGADLVLFCVKSPDTETAGAQLRPHLAPDTLVLTLQNGTDNAERLRTVIPQP-VS 119 +P V GA LVLFCVKS DTE A AQ+RPHL PD LVLTLQNG DN ER+R V+P V+ Sbjct: 61 EPNAVQGAQLVLFCVKSTDTEAAAAQIRPHLLPDALVLTLQNGVDNDERVRAVLPSSEVA 120 Query: 120 AAVVYVATEMAGPGHVKHHGRGELVIEPSARSQQAAEALIAAGVPTEISENVRGALWLKL 179 AAVVYVATEMAGPGHVKHHGRGELVI PS RS+Q A+ L+AAGVPT+IS NVRG+LW KL Sbjct: 121 AAVVYVATEMAGPGHVKHHGRGELVIAPSHRSEQVAQQLVAAGVPTQISGNVRGSLWAKL 180 Query: 180 IINCAYNALSAITLLPYGKLVEGVGVLEVMDHLVSECKAVAAAEGVTLAGDVDVAIRKII 239 ++NCAYNALSA++ LPYG+LV+GVGV EV+ +V+EC AVA AEGV + GD D AIR I Sbjct: 181 VLNCAYNALSAVSQLPYGELVKGVGVAEVIRDVVAECLAVAKAEGVEIPGDTDAAIRGIA 240 Query: 240 ETMPTQFSSTAQDVARGKPSEIDHLNGYIVRRGQAHGIATPVNLTVHALVKLIESKAR 297 ++MP+Q+SSTAQD+ARGKPSEIDHLNG++VRRG+A G+ TP N + +VKL+E K R Sbjct: 241 QSMPSQYSSTAQDLARGKPSEIDHLNGFVVRRGEALGVPTPANRVLSVMVKLLEGKQR 298 >ref|YP_004157901.1| 2-dehydropantoate 2-reductase [Variovorax paradoxus EPS] gb|ADU39790.1| 2-dehydropantoate 2-reductase [Variovorax paradoxus EPS] Length = 301 Score = 375 bits (963), Expect = e-102, Method: Composition-based stats. Identities = 203/297 (68%), Positives = 247/297 (83%) Query: 1 MKVAVMGAGAVGCYFAGMLARAGHDVVLVGRPQHVEAFNTKGLRLEAKTFDETLPVEAST 60 MKVAVMGAGAVGCY+ MLARAGH+VVL+GRP HVEA GLRLE KTFDE + ++AST Sbjct: 1 MKVAVMGAGAVGCYYGAMLARAGHEVVLIGRPSHVEAVKANGLRLETKTFDEQVRLDAST 60 Query: 61 DPAIVAGADLVLFCVKSPDTETAGAQLRPHLAPDTLVLTLQNGTDNAERLRTVIPQPVSA 120 + + V GADLVLFCVKS D+E+A AQ++PHL+PD LVLTLQNG DN ER+R+V+ V+A Sbjct: 61 EASAVQGADLVLFCVKSTDSESAAAQIKPHLSPDALVLTLQNGVDNDERVRSVLSNEVAA 120 Query: 121 AVVYVATEMAGPGHVKHHGRGELVIEPSARSQQAAEALIAAGVPTEISENVRGALWLKLI 180 AVVYVATEMAG GHVKHHGRGELVI PS S++ AE LIAAGVPT+IS+NVRG+LW KLI Sbjct: 121 AVVYVATEMAGAGHVKHHGRGELVIAPSRASERVAEHLIAAGVPTQISDNVRGSLWAKLI 180 Query: 181 INCAYNALSAITLLPYGKLVEGVGVLEVMDHLVSECKAVAAAEGVTLAGDVDVAIRKIIE 240 +NCAYNALSA++ LPYG+LV+GVGV +V+ +V+EC AVAAAEGV + GD D AIR I + Sbjct: 181 LNCAYNALSAVSQLPYGELVKGVGVNDVIRDVVAECLAVAAAEGVVIPGDTDAAIRGIAQ 240 Query: 241 TMPTQFSSTAQDVARGKPSEIDHLNGYIVRRGQAHGIATPVNLTVHALVKLIESKAR 297 +MP+Q+SSTAQD+ARGK SEIDHLNG +VRRG+A G+ TP N + +VKL+E K + Sbjct: 241 SMPSQYSSTAQDLARGKLSEIDHLNGLVVRRGEALGVPTPANRVLFVMVKLLEGKQQ 297 >ref|YP_549741.1| 2-dehydropantoate 2-reductase [Polaromonas sp. JS666] gb|ABE44843.1| ketopantoate reductase [Polaromonas sp. JS666] Length = 313 Score = 375 bits (962), Expect = e-102, Method: Composition-based stats. Identities = 214/300 (71%), Positives = 248/300 (82%), Gaps = 5/300 (1%) Query: 1 MKVAVMGAGAVGCYFAGMLARAGHDVVLVGRPQHVEAFNTKGLRLEAKTFDETLPVEAST 60 +KVAVMGAGAVGCYF GMLARAGH+VVL+ RPQHVEA GLR+E KTFDE + + AS Sbjct: 5 LKVAVMGAGAVGCYFGGMLARAGHEVVLIARPQHVEAIARDGLRMETKTFDEHVRLAASA 64 Query: 61 DPAIVAGADLVLFCVKSPDTETAGAQLRPHLAPDTLVLTLQNGTDNAERLRTVIPQ-PVS 119 DP V GA+LVLF VKS DTE+AGAQ+RPHL+ D LVL LQNG DNA+RLRTV+PQ V+ Sbjct: 65 DPGAVQGANLVLFSVKSTDTESAGAQIRPHLSADALVLCLQNGVDNADRLRTVLPQHAVA 124 Query: 120 AAVVYVATEMAGPGHVKHHGRGELVIEPSAR----SQQAAEALIAAGVPTEISENVRGAL 175 AAVVYVATEMAGPGHVKHHGRGELVIEP++ S+ A+ALIAAGVPTEIS NVRGAL Sbjct: 125 AAVVYVATEMAGPGHVKHHGRGELVIEPASSASFSSEVVAQALIAAGVPTEISGNVRGAL 184 Query: 176 WLKLIINCAYNALSAITLLPYGKLVEGVGVLEVMDHLVSECKAVAAAEGVTLAGDVDVAI 235 W KLI+NCAYNA+SAI LPYGK V+G GV +VM +V+EC AVA AEGV + GDVD A+ Sbjct: 185 WAKLILNCAYNAVSAIAQLPYGKTVQGEGVKDVMRDVVAECLAVAKAEGVQVPGDVDAAV 244 Query: 236 RKIIETMPTQFSSTAQDVARGKPSEIDHLNGYIVRRGQAHGIATPVNLTVHALVKLIESK 295 RKI ETMP+QFSSTAQD+ARGK SEID+LNG IV+RG+A G+ATP N + ALVKL+E + Sbjct: 245 RKIAETMPSQFSSTAQDLARGKRSEIDYLNGLIVQRGEALGVATPANRVLWALVKLLEGQ 304