BLASTP 2.2.17 [Aug-26-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= 0001.2186.p (249 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003775214.1| short-chain dehydrogenase [Herbaspirillum se... 363 2e-98 gb|ADI19341.1| 8 dehydrogenases with different specificities (re... 315 4e-84 ref|YP_004753205.1| Short-chain dehydrogenase/reductase SDR [Col... 307 1e-81 gb|ADI19245.1| dehydrogenases with different specificities (rela... 305 4e-81 dbj|GAA18830.1| probable short chain dehydrogenase [Pseudomonas ... 292 3e-77 >ref|YP_003775214.1| short-chain dehydrogenase [Herbaspirillum seropedicae SmR1] gb|ADJ63306.1| short-chain dehydrogenase protein [Herbaspirillum seropedicae SmR1] Length = 251 Score = 363 bits (931), Expect = 2e-98, Method: Composition-based stats. Identities = 221/249 (88%), Positives = 235/249 (94%) Query: 1 MTDKVIIVTGGSRGIGAATALLAGQGGYAVCVNYVSNREAAESVAGQIRAAGGRAITVAG 60 M DKVI+VTGGSRGIGAATALLAGQ GYAV VNYV+NR AA++V QI+AAGGRAI V G Sbjct: 3 MADKVILVTGGSRGIGAATALLAGQRGYAVAVNYVTNRAAADAVVAQIQAAGGRAIAVGG 62 Query: 61 DVSKEEDVLRLFTTTDQELGRVTALVNNAGILDHQSRLDAMSAERITRVLVANVTGSLLC 120 DV++EEDVL+LF T D ELGRVTALVNNAG+LDHQSRL+ MSAERI RVL+ANVTGSLLC Sbjct: 63 DVAREEDVLQLFATVDGELGRVTALVNNAGVLDHQSRLEDMSAERINRVLIANVTGSLLC 122 Query: 121 AREAVKRMSTRHGGQGGAIVNLSSMAAKLGGPGEYVDYAASKGAIDAFTIGLAKEVAAEG 180 AREAVKRMSTRHGGQGGAIVNLSSMAAKLGGPGEYVDYAASKGAIDAFTIGLAKEVAAEG Sbjct: 123 AREAVKRMSTRHGGQGGAIVNLSSMAAKLGGPGEYVDYAASKGAIDAFTIGLAKEVAAEG 182 Query: 181 IRVNAVRPGLIYTDIHASGGEAGRVDRLKDAVPMKRGGTAEEVANAILWLLSDESSYATG 240 IRVNAVRPGLIYTDIHASGGEAGRVDRLKDAVPMKRGG+A EVANAILWLLS+E+SYATG Sbjct: 183 IRVNAVRPGLIYTDIHASGGEAGRVDRLKDAVPMKRGGSAAEVANAILWLLSEEASYATG 242 Query: 241 TFIDVSGGR 249 TFIDVSGGR Sbjct: 243 TFIDVSGGR 251 >gb|ADI19341.1| 8 dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [uncultured delta proteobacterium HF0500_03A04] Length = 268 Score = 315 bits (807), Expect = 4e-84, Method: Composition-based stats. Identities = 176/249 (70%), Positives = 211/249 (84%) Query: 1 MTDKVIIVTGGSRGIGAATALLAGQGGYAVCVNYVSNREAAESVAGQIRAAGGRAITVAG 60 + +KV+IVTGGSRGIGAATALLA + GY VCVNY + AA+SV G I A GGRAI VAG Sbjct: 20 LMNKVLIVTGGSRGIGAATALLAAKQGYGVCVNYQTRVNAADSVVGAILAEGGRAIAVAG 79 Query: 61 DVSKEEDVLRLFTTTDQELGRVTALVNNAGILDHQSRLDAMSAERITRVLVANVTGSLLC 120 D+S EE+V+R+F T+++LG+VTALVNNAG+L+ Q R++AM+ ER +RVL NV GS LC Sbjct: 80 DISSEEEVVRVFGETEEQLGQVTALVNNAGVLEPQMRMEAMTPERWSRVLAINVIGSFLC 139 Query: 121 AREAVKRMSTRHGGQGGAIVNLSSMAAKLGGPGEYVDYAASKGAIDAFTIGLAKEVAAEG 180 AREA+KRMS + GG GG IVN+SS+AAKLG PGEYVDYAASK A+DA T+GLAKEVA EG Sbjct: 140 AREAIKRMSMKSGGNGGVIVNVSSIAAKLGAPGEYVDYAASKAAVDAMTMGLAKEVATEG 199 Query: 181 IRVNAVRPGLIYTDIHASGGEAGRVDRLKDAVPMKRGGTAEEVANAILWLLSDESSYATG 240 IRVNAVRPG+IYT+IHASGGE RVDR+K++VPMKRGG EEVA+AILWLLS+E+SY TG Sbjct: 200 IRVNAVRPGVIYTEIHASGGEPKRVDRVKNSVPMKRGGNPEEVASAILWLLSEEASYVTG 259 Query: 241 TFIDVSGGR 249 F+DVSGGR Sbjct: 260 AFVDVSGGR 268 >ref|YP_004753205.1| Short-chain dehydrogenase/reductase SDR [Collimonas fungivorans Ter331] gb|AEK62382.1| Short-chain dehydrogenase/reductase SDR precursor [Collimonas fungivorans Ter331] Length = 273 Score = 307 bits (786), Expect = 1e-81, Method: Composition-based stats. Identities = 182/249 (73%), Positives = 209/249 (83%) Query: 1 MTDKVIIVTGGSRGIGAATALLAGQGGYAVCVNYVSNREAAESVAGQIRAAGGRAITVAG 60 M+ +VI++TG SRGIGAATA LA GYAVCVNYV NR AAE V IR AGG A+ VAG Sbjct: 25 MSKQVIVITGASRGIGAATAHLAAARGYAVCVNYVHNRSAAEQVVDAIRQAGGEALAVAG 84 Query: 61 DVSKEEDVLRLFTTTDQELGRVTALVNNAGILDHQSRLDAMSAERITRVLVANVTGSLLC 120 DV+ E DVL+LF T D +LG++TALVNNAGIL+ Q R++ M R+ RV N+ GS LC Sbjct: 85 DVAVEADVLKLFQTVDAQLGKLTALVNNAGILERQMRVEEMDVARLQRVFATNIVGSFLC 144 Query: 121 AREAVKRMSTRHGGQGGAIVNLSSMAAKLGGPGEYVDYAASKGAIDAFTIGLAKEVAAEG 180 AREAV+RMST GGQGGAIVNLSSMAAKLGGPGEYVDYAASKGAIDA T+GLAKEVA +G Sbjct: 145 AREAVRRMSTSLGGQGGAIVNLSSMAAKLGGPGEYVDYAASKGAIDAMTVGLAKEVAGQG 204 Query: 181 IRVNAVRPGLIYTDIHASGGEAGRVDRLKDAVPMKRGGTAEEVANAILWLLSDESSYATG 240 IRVNAVRPG+IYTDIHASGGE GRVDR+KD VPM+RGG+AEEVA AI+WL+SDE+SY+TG Sbjct: 205 IRVNAVRPGVIYTDIHASGGEPGRVDRVKDTVPMRRGGSAEEVARAIMWLVSDEASYSTG 264 Query: 241 TFIDVSGGR 249 FIDV+GGR Sbjct: 265 AFIDVAGGR 273 >gb|ADI19245.1| dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [uncultured delta proteobacterium HF0200_14D13] Length = 248 Score = 305 bits (781), Expect = 4e-81, Method: Composition-based stats. Identities = 174/246 (70%), Positives = 206/246 (83%) Query: 4 KVIIVTGGSRGIGAATALLAGQGGYAVCVNYVSNREAAESVAGQIRAAGGRAITVAGDVS 63 KV+IVTGGSRGIGAATALLA + Y+VCVNY ++ +AAE+V +I A G+A +AGDVS Sbjct: 3 KVVIVTGGSRGIGAATALLAAKQNYSVCVNYHASAKAAEAVVQKICAERGQAFAIAGDVS 62 Query: 64 KEEDVLRLFTTTDQELGRVTALVNNAGILDHQSRLDAMSAERITRVLVANVTGSLLCARE 123 E DV+R+F +++LG VTALVNNAG+L+ Q RL+ M+ ER +RVL NV GS LCARE Sbjct: 63 LEADVVRMFEEAEKQLGPVTALVNNAGVLEQQMRLEQMTPERWSRVLAINVVGSFLCARE 122 Query: 124 AVKRMSTRHGGQGGAIVNLSSMAAKLGGPGEYVDYAASKGAIDAFTIGLAKEVAAEGIRV 183 AV+ MST+ GG GGAIVN+SS A +LGGPGEYVDYAASKGA+DA TIGLAKEVA EGIRV Sbjct: 123 AVRWMSTKSGGSGGAIVNVSSRATQLGGPGEYVDYAASKGAVDAMTIGLAKEVADEGIRV 182 Query: 184 NAVRPGLIYTDIHASGGEAGRVDRLKDAVPMKRGGTAEEVANAILWLLSDESSYATGTFI 243 NAVRPG+IYTDIHASGGE GRVDR+K +VPM+RGG EEVA +ILWLLSDE+SY TGTF+ Sbjct: 183 NAVRPGVIYTDIHASGGEPGRVDRVKSSVPMQRGGQPEEVAASILWLLSDEASYVTGTFV 242 Query: 244 DVSGGR 249 DVSGGR Sbjct: 243 DVSGGR 248 >dbj|GAA18830.1| probable short chain dehydrogenase [Pseudomonas aeruginosa NCMG1179] Length = 248 Score = 292 bits (747), Expect = 3e-77, Method: Composition-based stats. Identities = 167/245 (68%), Positives = 204/245 (83%) Query: 5 VIIVTGGSRGIGAATALLAGQGGYAVCVNYVSNREAAESVAGQIRAAGGRAITVAGDVSK 64 V+++TG SRGIGAATALLA + GYAV +NY+ NREAAE++ +I GG A+ VA DV++ Sbjct: 4 VMLITGASRGIGAATALLAAERGYAVVLNYLRNREAAEALHQRIERQGGEALAVAADVAE 63 Query: 65 EEDVLRLFTTTDQELGRVTALVNNAGILDHQSRLDAMSAERITRVLVANVTGSLLCAREA 124 E DV RLF D+ GR+ LVNNAG+L+ Q+RL+ + A R+ RV NVTGS LCAREA Sbjct: 64 EGDVERLFAAIDERFGRLDVLVNNAGVLEAQTRLENIDAARLHRVFATNVTGSFLCAREA 123 Query: 125 VKRMSTRHGGQGGAIVNLSSMAAKLGGPGEYVDYAASKGAIDAFTIGLAKEVAAEGIRVN 184 VKR+STRHGG+GG+IVN+SSMA++LG P EY+DYAA+KGAID+ TIGLA+EVAAEGIRVN Sbjct: 124 VKRLSTRHGGRGGSIVNVSSMASRLGSPNEYIDYAAAKGAIDSMTIGLAREVAAEGIRVN 183 Query: 185 AVRPGLIYTDIHASGGEAGRVDRLKDAVPMKRGGTAEEVANAILWLLSDESSYATGTFID 244 AVRPGLI T+IHASGGE GR++RLK +P+ RGGTAEEVA AILWL SDE+SY+TGTFID Sbjct: 184 AVRPGLIDTEIHASGGEPGRIERLKGGIPLGRGGTAEEVARAILWLASDEASYSTGTFID 243 Query: 245 VSGGR 249 VSGGR Sbjct: 244 VSGGR 248