BLASTP 2.2.17 [Aug-26-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= 0001.1856.p (518 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003777869.1| D-xylose ABC transporter ATPase [Herbaspiril... 975 0.0 ref|YP_004753801.1| D-xylose transport ATP-binding protein xylG ... 834 0.0 ref|YP_348033.1| xylose transporter ATP-binding subunit [Pseudom... 803 0.0 ref|ZP_07004938.1| D-xylose transport ATP-binding protein xylG [... 801 0.0 ref|ZP_06459435.1| xylose transporter ATP-binding subunit [Pseud... 801 0.0 >ref|YP_003777869.1| D-xylose ABC transporter ATPase [Herbaspirillum seropedicae SmR1] gb|ADJ65961.1| ABC-type D-xylose transport system, ATPase component protein [Herbaspirillum seropedicae SmR1] Length = 518 Score = 975 bits (2521), Expect = 0.0, Method: Composition-based stats. Identities = 498/517 (96%), Positives = 509/517 (98%) Query: 1 MSEYLLEMKGIVKSFGGVRALDGIDIKIRPGECVGLCGENGAGKSTLMKILSGVYPHGTW 60 MSEYLLEMKGIVKSFGGVRAL+GIDIKIRPGECVGLCGENGAGKSTLMKILSGVYPHGTW Sbjct: 1 MSEYLLEMKGIVKSFGGVRALNGIDIKIRPGECVGLCGENGAGKSTLMKILSGVYPHGTW 60 Query: 61 DGEILWDGKPLQAHSVRDTEAAGIVIIHQELMLVPELSVAENIFMGHEITLPGGRMNYPA 120 +GEILWDGKPLQAHSVRDTEAAGIVIIHQELMLVPELSVAENIFMGHEITLPGGRMNYPA Sbjct: 61 EGEILWDGKPLQAHSVRDTEAAGIVIIHQELMLVPELSVAENIFMGHEITLPGGRMNYPA 120 Query: 121 MYRRAEELMRELNMPDINVALPVSQYGGGHQQLVEIAKALNKDARLLILDEPSSSLTASE 180 MYRRAEELMRELNMPDINVALPVSQYGGGHQQLVEIAKALNKDARLLILDEPSSSLTASE Sbjct: 121 MYRRAEELMRELNMPDINVALPVSQYGGGHQQLVEIAKALNKDARLLILDEPSSSLTASE 180 Query: 181 IAVLLKIIKDLKARGVACVYISHKLDEVAEICDTISVIRDGKHIATTPMQDMDVDKIITQ 240 I VLLKIIKDLKARGVACVYISHKLDEVAE+CDTISVIRDGKHIATTPMQ+MDVDKIITQ Sbjct: 181 IGVLLKIIKDLKARGVACVYISHKLDEVAEVCDTISVIRDGKHIATTPMQEMDVDKIITQ 240 Query: 241 MVGREITAMYPERNHAIGEVVLEARNITCYDIDNPRRKRVDDVSFSVRRGEILGIAGLVG 300 MVGREITAMYPERNHAIGEVVLEARNITCYDIDNPRRKRVDDVSFSVRRGEILGIAGLVG Sbjct: 241 MVGREITAMYPERNHAIGEVVLEARNITCYDIDNPRRKRVDDVSFSVRRGEILGIAGLVG 300 Query: 301 AGRTELVSAIFGAYRGRYEGQVLLEGKPADTGSPLKSIRQGLCMVPEDRKHHGIVPDLDV 360 AGRTELVSAIFGAYRGRYEGQVLLEGKPADT SPLKSIR+GLCMVPEDRKHHGIVPDLDV Sbjct: 301 AGRTELVSAIFGAYRGRYEGQVLLEGKPADTSSPLKSIRRGLCMVPEDRKHHGIVPDLDV 360 Query: 361 GQNITLTVLNRFSRGTRIDSSAELKTIQGEISRLRVKTASPFLPITGLSGGNQQKAVLSK 420 GQNITLTVLNRFSRG+RID SAELKTIQ EI R+RVKTA+PFLPIT LSGGNQQKAVL+K Sbjct: 361 GQNITLTVLNRFSRGSRIDGSAELKTIQDEIGRMRVKTATPFLPITSLSGGNQQKAVLAK 420 Query: 421 MLLAQPKVLILDEPTRGVDVGAKAEIYRLISELAKLGLAIIMVSSELAEVLGVSDRVLVI 480 MLLAQPKVLILDEPTRGVDVGAKAEIYRLISELAK GLAIIMVSSELAEVLGVSDRVLVI Sbjct: 421 MLLAQPKVLILDEPTRGVDVGAKAEIYRLISELAKAGLAIIMVSSELAEVLGVSDRVLVI 480 Query: 481 GEGKLRGDFVNDNLSQETVLAAAINQPVPQASPRAVA 517 GEG+LRGDFVNDNLSQETVLAAAINQPVPQA+PRA A Sbjct: 481 GEGRLRGDFVNDNLSQETVLAAAINQPVPQATPRAAA 517 >ref|YP_004753801.1| D-xylose transport ATP-binding protein xylG [Collimonas fungivorans Ter331] gb|AEK62978.1| D-xylose transport ATP-binding protein xylG [Collimonas fungivorans Ter331] Length = 528 Score = 834 bits (2154), Expect = 0.0, Method: Composition-based stats. Identities = 415/506 (82%), Positives = 466/506 (92%) Query: 1 MSEYLLEMKGIVKSFGGVRALDGIDIKIRPGECVGLCGENGAGKSTLMKILSGVYPHGTW 60 MS+YLLEM+GIVK FG VRALDGIDIK++ GEC+GLCGENGAGKSTLMK+LSGVYPHG+W Sbjct: 1 MSDYLLEMRGIVKEFGAVRALDGIDIKVKAGECLGLCGENGAGKSTLMKVLSGVYPHGSW 60 Query: 61 DGEILWDGKPLQAHSVRDTEAAGIVIIHQELMLVPELSVAENIFMGHEITLPGGRMNYPA 120 GEILW G PLQ+ S+RDTEAAGI+IIHQELMLV ELSVAENIFMGHE+TLPGGRMNYPA Sbjct: 61 QGEILWQGTPLQSQSMRDTEAAGIIIIHQELMLVQELSVAENIFMGHELTLPGGRMNYPA 120 Query: 121 MYRRAEELMRELNMPDINVALPVSQYGGGHQQLVEIAKALNKDARLLILDEPSSSLTASE 180 MYRRA ELMREL MPDINVALPV YGGGHQQLVEIAKALNK A+LLILDEPSSSLTASE Sbjct: 121 MYRRAAELMRELKMPDINVALPVMNYGGGHQQLVEIAKALNKQAKLLILDEPSSSLTASE 180 Query: 181 IAVLLKIIKDLKARGVACVYISHKLDEVAEICDTISVIRDGKHIATTPMQDMDVDKIITQ 240 IAVLL II+DLKA+GVACVYISHKLDEVA +CDT++VIRDGKHIATTPMQDM+VD+IITQ Sbjct: 181 IAVLLDIIRDLKAKGVACVYISHKLDEVAAVCDTVAVIRDGKHIATTPMQDMNVDRIITQ 240 Query: 241 MVGREITAMYPERNHAIGEVVLEARNITCYDIDNPRRKRVDDVSFSVRRGEILGIAGLVG 300 MVGREI+AMYP++ H IGEV+ EAR++TC+D DNP+RKRVDD+SFS+RRGEILGIAGLVG Sbjct: 241 MVGREISAMYPDQEHEIGEVMFEARHVTCHDADNPQRKRVDDISFSLRRGEILGIAGLVG 300 Query: 301 AGRTELVSAIFGAYRGRYEGQVLLEGKPADTGSPLKSIRQGLCMVPEDRKHHGIVPDLDV 360 AGRTELVSA+FGAY GR + +V L+G DT +PLK+IR GLCMVPEDRK HGIVPDL V Sbjct: 301 AGRTELVSALFGAYPGRSQAEVWLDGVKVDTSTPLKAIRLGLCMVPEDRKQHGIVPDLSV 360 Query: 361 GQNITLTVLNRFSRGTRIDSSAELKTIQGEISRLRVKTASPFLPITGLSGGNQQKAVLSK 420 GQNITL VL FSR TRID+ AELKT+Q EI RL++KT+SPFLPIT LSGGNQQKAVL+K Sbjct: 361 GQNITLAVLKNFSRNTRIDAEAELKTVQAEIGRLQLKTSSPFLPITSLSGGNQQKAVLAK 420 Query: 421 MLLAQPKVLILDEPTRGVDVGAKAEIYRLISELAKLGLAIIMVSSELAEVLGVSDRVLVI 480 MLLA+PKVLILDEPTRGVDVGAKAEIYRL+++LA+ G+AIIMVSSELAEVLGVSDRVLVI Sbjct: 421 MLLARPKVLILDEPTRGVDVGAKAEIYRLMADLARQGVAIIMVSSELAEVLGVSDRVLVI 480 Query: 481 GEGKLRGDFVNDNLSQETVLAAAINQ 506 GEGKLRG+F+N +LSQETVLAAAI+Q Sbjct: 481 GEGKLRGNFINRDLSQETVLAAAIDQ 506 >ref|YP_348033.1| xylose transporter ATP-binding subunit [Pseudomonas fluorescens Pf0-1] sp|Q3KDW2|XYLG_PSEPF RecName: Full=Xylose import ATP-binding protein XylG gb|ABA74044.1| xylose ABC transporter ATP-binding protein [Pseudomonas fluorescens Pf0-1] Length = 518 Score = 803 bits (2074), Expect = 0.0, Method: Composition-based stats. Identities = 398/507 (78%), Positives = 459/507 (90%) Query: 1 MSEYLLEMKGIVKSFGGVRALDGIDIKIRPGECVGLCGENGAGKSTLMKILSGVYPHGTW 60 MS+YLL+M GIVK+FGGV+AL+GID+K+RPGECVGLCGENGAGKSTLMKILS VYPHGTW Sbjct: 1 MSDYLLQMNGIVKTFGGVKALNGIDLKVRPGECVGLCGENGAGKSTLMKILSAVYPHGTW 60 Query: 61 DGEILWDGKPLQAHSVRDTEAAGIVIIHQELMLVPELSVAENIFMGHEITLPGGRMNYPA 120 DGEILWDG+PL+A S+ +TEAAGIVIIHQEL LVP+LSVAENIFMGHE+TLPGGRMNYPA Sbjct: 61 DGEILWDGQPLKAQSISETEAAGIVIIHQELTLVPDLSVAENIFMGHELTLPGGRMNYPA 120 Query: 121 MYRRAEELMRELNMPDINVALPVSQYGGGHQQLVEIAKALNKDARLLILDEPSSSLTASE 180 M RAE LMREL +PD+NV+LPVSQYGGG+QQLVEIAKALNK ARLLILDEPSS+LT SE Sbjct: 121 MIHRAEALMRELKVPDMNVSLPVSQYGGGYQQLVEIAKALNKQARLLILDEPSSALTRSE 180 Query: 181 IAVLLKIIKDLKARGVACVYISHKLDEVAEICDTISVIRDGKHIATTPMQDMDVDKIITQ 240 I VLL II+DLKA+GVACVYISHKLDEVA +CDTISVIRDG+HIATT M++MD+ +IITQ Sbjct: 181 IEVLLDIIRDLKAKGVACVYISHKLDEVAAVCDTISVIRDGQHIATTAMENMDIPQIITQ 240 Query: 241 MVGREITAMYPERNHAIGEVVLEARNITCYDIDNPRRKRVDDVSFSVRRGEILGIAGLVG 300 MVGRE++++YP H IGEV+ EAR+ITCYD+DNP+RKRVDDVSFS+RRGEILGIAGLVG Sbjct: 241 MVGREMSSLYPTEPHDIGEVIFEARHITCYDVDNPKRKRVDDVSFSLRRGEILGIAGLVG 300 Query: 301 AGRTELVSAIFGAYRGRYEGQVLLEGKPADTGSPLKSIRQGLCMVPEDRKHHGIVPDLDV 360 AGRTELV+A+FGAY GR+EG+V L+G P DT +PLKSIR G+C+VPEDRK GI+PDL V Sbjct: 301 AGRTELVTALFGAYPGRHEGEVWLDGHPIDTRTPLKSIRAGVCLVPEDRKRQGIIPDLGV 360 Query: 361 GQNITLTVLNRFSRGTRIDSSAELKTIQGEISRLRVKTASPFLPITGLSGGNQQKAVLSK 420 GQNITL VL+ FS+ TRID+ AEL +I EISRL +KTASPFLPIT LSGGNQQKAVL+K Sbjct: 361 GQNITLAVLDSFSKLTRIDAEAELGSIDREISRLHLKTASPFLPITSLSGGNQQKAVLAK 420 Query: 421 MLLAQPKVLILDEPTRGVDVGAKAEIYRLISELAKLGLAIIMVSSELAEVLGVSDRVLVI 480 MLL +P+VLILDEPTRGVDVGAK EIY+L+ LA G++IIMVSSELAEVLGVSDRVLVI Sbjct: 421 MLLTRPRVLILDEPTRGVDVGAKYEIYKLMGMLAAEGVSIIMVSSELAEVLGVSDRVLVI 480 Query: 481 GEGKLRGDFVNDNLSQETVLAAAINQP 507 GEG+L+GDFVN L+QE VLAAA++QP Sbjct: 481 GEGRLQGDFVNHELTQEQVLAAALSQP 507 Score = 86.7 bits (213), Expect = 1e-14, Method: Composition-based stats. Identities = 63/241 (26%), Positives = 120/241 (49%), Gaps = 13/241 (5%) Query: 278 KRVDDVSFSVRRGEILGIAGLVGAGRTELVSAIFGAY-RGRYEGQVLLEGKPADTGSPLK 336 K ++ + VR GE +G+ G GAG++ L+ + Y G ++G++L +G+P S + Sbjct: 19 KALNGIDLKVRPGECVGLCGENGAGKSTLMKILSAVYPHGTWDGEILWDGQPLKAQSISE 78 Query: 337 SIRQGLCMVPEDRKHHGIVPDLDVGQNI----TLTVLNRFSRGTRIDSSAELKTIQGEIS 392 + G+ ++ ++ +VPDL V +NI LT+ G R++ A + + + Sbjct: 79 TEAAGIVIIHQELT---LVPDLSVAENIFMGHELTL-----PGGRMNYPAMIHRAEALMR 130 Query: 393 RLRVKTASPFLPITGLSGGNQQKAVLSKMLLAQPKVLILDEPTRGVDVGAKAEIYRLISE 452 L+V + LP++ GG QQ ++K L Q ++LILDEP+ + + +I + Sbjct: 131 ELKVPDMNVSLPVSQYGGGYQQLVEIAKALNKQARLLILDEPSSALTRSEIEVLLDIIRD 190 Query: 453 LAKLGLAIIMVSSELAEVLGVSDRVLVIGEGKLRGDFVNDNLSQETVLAAAINQPVPQAS 512 L G+A + +S +L EV V D + VI +G+ +N+ ++ + + + Sbjct: 191 LKAKGVACVYISHKLDEVAAVCDTISVIRDGQHIATTAMENMDIPQIITQMVGREMSSLY 250 Query: 513 P 513 P Sbjct: 251 P 251 >ref|ZP_07004938.1| D-xylose transport ATP-binding protein xylG [Pseudomonas savastanoi pv. savastanoi NCPPB 3335] gb|EFH99813.1| D-xylose transport ATP-binding protein xylG [Pseudomonas savastanoi pv. savastanoi NCPPB 3335] Length = 518 Score = 801 bits (2070), Expect = 0.0, Method: Composition-based stats. Identities = 401/518 (77%), Positives = 457/518 (88%), Gaps = 1/518 (0%) Query: 1 MSEYLLEMKGIVKSFGGVRALDGIDIKIRPGECVGLCGENGAGKSTLMKILSGVYPHGTW 60 MS+YLL+M GIVK+F GV+AL+GIDIK+RPGECVGLCGENGAGKSTLMK+LS VYP+GTW Sbjct: 1 MSDYLLQMNGIVKTFDGVKALNGIDIKVRPGECVGLCGENGAGKSTLMKVLSAVYPYGTW 60 Query: 61 DGEILWDGKPLQAHSVRDTEAAGIVIIHQELMLVPELSVAENIFMGHEITLPGGRMNYPA 120 DGEILWDG PL+A S+ +TEAAGIVIIHQEL LVP+LSVAENIFMGHE+TLPGGRMNYPA Sbjct: 61 DGEILWDGNPLKAQSISETEAAGIVIIHQELTLVPDLSVAENIFMGHELTLPGGRMNYPA 120 Query: 121 MYRRAEELMRELNMPDINVALPVSQYGGGHQQLVEIAKALNKDARLLILDEPSSSLTASE 180 M RAE LMREL +PD+NVALPVSQYGGG+QQLVEIAKALNK ARLLILDEPSS+LT SE Sbjct: 121 MIHRAEVLMRELKVPDMNVALPVSQYGGGYQQLVEIAKALNKKARLLILDEPSSALTRSE 180 Query: 181 IAVLLKIIKDLKARGVACVYISHKLDEVAEICDTISVIRDGKHIATTPMQDMDVDKIITQ 240 I VLL II+DLKA+GVACVYISHKLDEVA +CDTISVIRDGKHIATT M DMD+ KIITQ Sbjct: 181 IEVLLDIIRDLKAKGVACVYISHKLDEVAAVCDTISVIRDGKHIATTAMSDMDIPKIITQ 240 Query: 241 MVGREITAMYPERNHAIGEVVLEARNITCYDIDNPRRKRVDDVSFSVRRGEILGIAGLVG 300 MVGRE++ +YP H IGEV+ EARNITCYD+DNP RKRVDD+SF+++RGEILGIAGLVG Sbjct: 241 MVGREMSNLYPTEPHEIGEVIFEARNITCYDVDNPGRKRVDDISFALKRGEILGIAGLVG 300 Query: 301 AGRTELVSAIFGAYRGRYEGQVLLEGKPADTGSPLKSIRQGLCMVPEDRKHHGIVPDLDV 360 AGRTELVSA+FGAY GRY G+V L+G+P DT +PLKSIR GLCMVPEDRK GI+PDL V Sbjct: 301 AGRTELVSALFGAYPGRYTGEVWLDGQPVDTRTPLKSIRAGLCMVPEDRKRQGIIPDLGV 360 Query: 361 GQNITLTVLNRFSRGTRIDSSAELKTIQGEISRLRVKTASPFLPITGLSGGNQQKAVLSK 420 GQNITL VL+ +S+ TRID+ AEL +I EISR+ +KTASPFLPIT LSGGNQQKAVL+K Sbjct: 361 GQNITLAVLDTYSKMTRIDAEAELGSIDREISRMHLKTASPFLPITSLSGGNQQKAVLAK 420 Query: 421 MLLAQPKVLILDEPTRGVDVGAKAEIYRLISELAKLGLAIIMVSSELAEVLGVSDRVLVI 480 MLL +P+VLILDEPTRGVDVGAK EIY+L+ LA G++IIMVSSELAEVLGVSDRVLVI Sbjct: 421 MLLTRPRVLILDEPTRGVDVGAKYEIYKLMGALAAEGVSIIMVSSELAEVLGVSDRVLVI 480 Query: 481 GEGKLRGDFVNDNLSQETVLAAAINQP-VPQASPRAVA 517 GEG+LRGDF+N L+QE VLAAA++ P P + R A Sbjct: 481 GEGQLRGDFINHELTQEQVLAAALSHPDAPDNNARKTA 518 >ref|ZP_06459435.1| xylose transporter ATP-binding subunit [Pseudomonas syringae pv. aesculi str. NCPPB3681] ref|ZP_06478511.1| xylose transporter ATP-binding subunit [Pseudomonas syringae pv. aesculi str. 2250] gb|EGH03040.1| xylose transporter ATP-binding subunit [Pseudomonas syringae pv. aesculi str. 0893_23] Length = 518 Score = 801 bits (2068), Expect = 0.0, Method: Composition-based stats. Identities = 400/518 (77%), Positives = 457/518 (88%), Gaps = 1/518 (0%) Query: 1 MSEYLLEMKGIVKSFGGVRALDGIDIKIRPGECVGLCGENGAGKSTLMKILSGVYPHGTW 60 MS+YLL+M GIVK+F G++AL+GIDIK+RPGECVGLCGENGAGKSTLMK+LS VYP+GTW Sbjct: 1 MSDYLLQMNGIVKTFDGIKALNGIDIKVRPGECVGLCGENGAGKSTLMKVLSAVYPYGTW 60 Query: 61 DGEILWDGKPLQAHSVRDTEAAGIVIIHQELMLVPELSVAENIFMGHEITLPGGRMNYPA 120 DGEILWDG PL+A S+ +TEAAGIVIIHQEL LVP+LSVAENIFMGHE+TLPGGRMNYPA Sbjct: 61 DGEILWDGNPLKAQSISETEAAGIVIIHQELTLVPDLSVAENIFMGHELTLPGGRMNYPA 120 Query: 121 MYRRAEELMRELNMPDINVALPVSQYGGGHQQLVEIAKALNKDARLLILDEPSSSLTASE 180 M RAE LMREL +PD+NVALPVSQYGGG+QQLVEIAKALNK ARLLILDEPSS+LT SE Sbjct: 121 MIHRAEVLMRELKVPDMNVALPVSQYGGGYQQLVEIAKALNKKARLLILDEPSSALTRSE 180 Query: 181 IAVLLKIIKDLKARGVACVYISHKLDEVAEICDTISVIRDGKHIATTPMQDMDVDKIITQ 240 I VLL II+DLKA+GVACVYISHKLDEVA +CDTISVIRDGKHIATT M DMD+ KIITQ Sbjct: 181 IEVLLDIIRDLKAKGVACVYISHKLDEVAAVCDTISVIRDGKHIATTAMSDMDIPKIITQ 240 Query: 241 MVGREITAMYPERNHAIGEVVLEARNITCYDIDNPRRKRVDDVSFSVRRGEILGIAGLVG 300 MVGRE++ +YP H IGEV+ EARNITCYD+DNP RKRVDD+SF+++RGEILGIAGLVG Sbjct: 241 MVGREMSNLYPTEPHEIGEVIFEARNITCYDVDNPGRKRVDDISFALKRGEILGIAGLVG 300 Query: 301 AGRTELVSAIFGAYRGRYEGQVLLEGKPADTGSPLKSIRQGLCMVPEDRKHHGIVPDLDV 360 AGRTELVSA+FGAY GRY G+V L+G+P DT +PLKSIR GLCMVPEDRK GI+PDL V Sbjct: 301 AGRTELVSALFGAYPGRYTGEVWLDGQPVDTRTPLKSIRAGLCMVPEDRKRQGIIPDLGV 360 Query: 361 GQNITLTVLNRFSRGTRIDSSAELKTIQGEISRLRVKTASPFLPITGLSGGNQQKAVLSK 420 GQNITL VL+ +S+ TRID+ AEL +I EISR+ +KTASPFLPIT LSGGNQQKAVL+K Sbjct: 361 GQNITLAVLDTYSKMTRIDAEAELGSIDREISRMHLKTASPFLPITSLSGGNQQKAVLAK 420 Query: 421 MLLAQPKVLILDEPTRGVDVGAKAEIYRLISELAKLGLAIIMVSSELAEVLGVSDRVLVI 480 MLL +P+VLILDEPTRGVDVGAK EIY+L+ LA G++IIMVSSELAEVLGVSDRVLVI Sbjct: 421 MLLTRPRVLILDEPTRGVDVGAKYEIYKLMGALAAEGVSIIMVSSELAEVLGVSDRVLVI 480 Query: 481 GEGKLRGDFVNDNLSQETVLAAAINQP-VPQASPRAVA 517 GEG+LRGDF+N L+QE VLAAA++ P P + R A Sbjct: 481 GEGQLRGDFINHELTQEQVLAAALSHPDAPDNNARKTA 518