BLASTP 2.2.17 [Aug-26-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= 0001.1750.p (465 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003773454.1| transmembrane sensory transduction histidine... 526 e-147 ref|YP_001354043.1| heavy metal sensor kinase [Janthinobacterium... 437 e-120 ref|YP_004753178.1| signal transduction histidine kinase [Collim... 356 6e-96 ref|ZP_08273803.1| Signal transduction histidine kinase [Oxaloba... 353 5e-95 ref|YP_841161.1| signal transduction histidine kinase [Ralstonia... 333 4e-89 >ref|YP_003773454.1| transmembrane sensory transduction histidine kinase for cobalt/zinc/ cadmium resistance transcription regulator protein [Herbaspirillum seropedicae SmR1] gb|ADJ61546.1| transmembrane sensory transduction histidine kinase for cobalt/zinc/ cadmium resistance transcription regulator protein [Herbaspirillum seropedicae SmR1] Length = 467 Score = 526 bits (1354), Expect = e-147, Method: Composition-based stats. Identities = 291/453 (64%), Positives = 360/453 (79%) Query: 1 MTTRLVALFALVAIVTFAAVGTYLYHSLYVQLERRDDEELIGKIRSIDHLIQEAQSIDSI 60 ++ RLVALF L+A+V AA+GTYL HSL+VQLERRDDEEL GK RSI+HL++ A S++ I Sbjct: 9 LSLRLVALFGLLAMVILAALGTYLSHSLHVQLERRDDEELAGKCRSINHLVEHAASLEDI 68 Query: 61 KANNHAMLDTISGHDQLLMLITDASGVAILKNYSGPVELRTSLFSTLQATQTNALQSIDW 120 A H +LDT++GHDQLL+ I A G +L+++ S + +++QS Sbjct: 69 LARRHLVLDTLTGHDQLLVRIARADGSTLLESHDPTRTPPGIDLSQVDIRAWDSIQSWKL 128 Query: 121 EGNRIRFIASSPTTSAGEKTRVIVARTVSDRMVLLADYRTEVWYAATIGTLLATLLSLFL 180 R R++AS P T +GE+ V+V RT SDRM+LLA+YR++VW+AA +G LLA L+S FL Sbjct: 129 GDLRARYVASKPVTRSGEQAVVLVVRTASDRMLLLAEYRSDVWWAAGVGALLAILMSYFL 188 Query: 181 VRSGLRPLRLMAAQTHAVSASRLDTRLDIRSAPKELHEIVESFNAMLDRLHRSFEQLTQF 240 VRSGLRPLR MAAQT AVSA+RLDTRLD+++AP+ELHEIVESFN MLDRLHRSF+QL+QF Sbjct: 189 VRSGLRPLRTMAAQTRAVSANRLDTRLDLQAAPRELHEIVESFNEMLDRLHRSFQQLSQF 248 Query: 241 SADLAHDLRTPLNNLMVQTQVALGKPRSLEEYQGLLSSNIEEYERLARMMESMLFLARAE 300 SADLAHD+RTPLNNLMVQTQVALGKPR ++EYQ LLSSNIEEYERL+RMMESMLFLARAE Sbjct: 249 SADLAHDVRTPLNNLMVQTQVALGKPRGIDEYQALLSSNIEEYERLSRMMESMLFLARAE 308 Query: 301 NAHVAVKPQMLSVEDELAKIADYFEGIAEEADVRIVVSGTGDIFADPMLLRRALGNLISN 360 NAHV ++ Q L V EL +IADYFEGIA+EA VR+VV G G + AD LLRRA+GNL++N Sbjct: 309 NAHVVLQWQELDVAQELTRIADYFEGIADEAQVRLVVQGAGRLQADATLLRRAVGNLVAN 368 Query: 361 AIRYTPKERIIRVEATDLDDATILTVSNPGEGIPPDVVGRIFDRFYRADPSRSSASGSSG 420 AIRYTP + +IR++ D ++VSNPG GIP + + R+FDRFYRADPSRSSA GSSG Sbjct: 369 AIRYTPADGVIRLQVDAAGDGMEISVSNPGAGIPAEQLERLFDRFYRADPSRSSAGGSSG 428 Query: 421 LGLAIVRSIMMLHGGEATVKSTQGERTIFSLTF 453 LGLAIVRSIMMLHGG+A+V S+ G+ T+FSL F Sbjct: 429 LGLAIVRSIMMLHGGQASVTSSPGQLTVFSLRF 461 >ref|YP_001354043.1| heavy metal sensor kinase [Janthinobacterium sp. Marseille] gb|ABR89313.1| heavy metal sensor kinase [Janthinobacterium sp. Marseille] Length = 466 Score = 437 bits (1123), Expect = e-120, Method: Composition-based stats. Identities = 242/455 (53%), Positives = 318/455 (69%), Gaps = 2/455 (0%) Query: 1 MTTRLVALFALVAIVTFAAVGTYLYHSLYVQLERRDDEELIGKIRSIDHLIQEAQSIDSI 60 +T+R+ LF LV+++ F+ VGTYLY SL QLE RDD+EL+GKI + HL +E+ SI +I Sbjct: 9 LTSRIGLLFFLVSVLIFSGVGTYLYRSLAGQLEFRDDQELMGKISLMRHLAEESDSIAAI 68 Query: 61 KANNHAMLDTISGHDQLLMLITDASGVAILKNYSGPVELRTSLFSTLQATQTNALQSIDW 120 + + H LD + HD+L++++ D G IL S L T L+ ++ W Sbjct: 69 RKDPHYFLDAAASHDRLIIMLKDVDGNIILHTNSDQGSLPTIAVLPLEMNPVPRSITLLW 128 Query: 121 E--GNRIRFIASSPTTSAGEKTRVIVARTVSDRMVLLADYRTEVWYAATIGTLLATLLSL 178 G R IA+ +GEK ++VART SDRM LL YR E+ AA GTLLA LL Sbjct: 129 TSTGLTARAIAAQGKVRSGEKIVIVVARTASDRMELLKAYRVEIGMAALCGTLLAALLGY 188 Query: 179 FLVRSGLRPLRLMAAQTHAVSASRLDTRLDIRSAPKELHEIVESFNAMLDRLHRSFEQLT 238 LVR GLRP+RL+A Q +++A RLDTRLD+ SAP+ELHE+V++FNAMLDRL SF++L+ Sbjct: 189 ILVRRGLRPVRLIAGQASSITAHRLDTRLDLSSAPQELHELVQAFNAMLDRLDGSFQRLS 248 Query: 239 QFSADLAHDLRTPLNNLMVQTQVALGKPRSLEEYQGLLSSNIEEYERLARMMESMLFLAR 298 QFSADLAHDLRTPLNNLMVQTQVAL + RS+E+YQGLL SN+EEYERL RM+ESMLFLAR Sbjct: 249 QFSADLAHDLRTPLNNLMVQTQVALVQARSVEDYQGLLISNVEEYERLTRMVESMLFLAR 308 Query: 299 AENAHVAVKPQMLSVEDELAKIADYFEGIAEEADVRIVVSGTGDIFADPMLLRRALGNLI 358 E+ HV + LS+ +EL +IADYFEG+A+EA VR+ V G ++AD +LLRRA+GNL+ Sbjct: 309 VEHTHVMLNKSALSLPEELQRIADYFEGLADEAGVRLTVEAGGRVYADAILLRRAIGNLV 368 Query: 359 SNAIRYTPKERIIRVEATDLDDATILTVSNPGEGIPPDVVGRIFDRFYRADPSRSSASGS 418 +NAI YTP+ I ++ D ++V NPG GI + +F+RFYR D +RS+++ S Sbjct: 369 ANAIPYTPRGATIVLKGVMTADGATVSVVNPGAGIAAQHIPHVFNRFYRGDAARSNSATS 428 Query: 419 SGLGLAIVRSIMMLHGGEATVKSTQGERTIFSLTF 453 +GLGLAIV+SIM LHGG ATV S + T FSL F Sbjct: 429 TGLGLAIVQSIMALHGGRATVTSEENGLTEFSLIF 463 >ref|YP_004753178.1| signal transduction histidine kinase [Collimonas fungivorans Ter331] gb|AEK62355.1| signal transduction histidine kinase [Collimonas fungivorans Ter331] Length = 393 Score = 356 bits (913), Expect = 6e-96, Method: Composition-based stats. Identities = 201/396 (50%), Positives = 266/396 (67%), Gaps = 17/396 (4%) Query: 68 LDTISGHDQLLMLITDASGVAILKNYSGPVELRTSLFSTLQATQTNALQSIDWEGNR-IR 126 +D GHD LL+++ A G +L + R S T A Q D E + +R Sbjct: 1 MDATLGHDDLLLILRSADGAPLL-------DTRPEAGSLPALPMTAAGQEPDQESRQNLR 53 Query: 127 FIASSPT---------TSAGEKTRVIVARTVSDRMVLLADYRTEVWYAATIGTLLATLLS 177 A P S GEK ++IVA SD + +LA YR ++ AA G +LA LL Sbjct: 54 TSAGLPVRATALWANIDSTGEKVQIIVAHNTSDSIAMLASYRQQILGAALSGAILAALLG 113 Query: 178 LFLVRSGLRPLRLMAAQTHAVSASRLDTRLDIRSAPKELHEIVESFNAMLDRLHRSFEQL 237 LVR GLRP RL+A Q H+++A RLD LD+ SAP EL ++V +FN MLDRLH SF++L Sbjct: 114 YVLVRRGLRPARLIAQQAHSITAQRLDRGLDVASAPYELQQLVVAFNGMLDRLHDSFQRL 173 Query: 238 TQFSADLAHDLRTPLNNLMVQTQVALGKPRSLEEYQGLLSSNIEEYERLARMMESMLFLA 297 +QFSADLAHDLRTP+NNLMVQTQVAL +PR EEYQGLL SN+EEYERLARM+++MLFLA Sbjct: 174 SQFSADLAHDLRTPINNLMVQTQVALAQPRLPEEYQGLLVSNVEEYERLARMLDNMLFLA 233 Query: 298 RAENAHVAVKPQMLSVEDELAKIADYFEGIAEEADVRIVVSGTGDIFADPMLLRRALGNL 357 RA++AHVAV L EL +IADYFEG+AE++ V + ++ +G+I AD MLLRRA+ NL Sbjct: 234 RADHAHVAVAFGELDCRLELQRIADYFEGVAEDSGVCLEIAASGNIRADAMLLRRAISNL 293 Query: 358 ISNAIRYTPKERIIRVEATDLDDATILTVSNPGEGIPPDVVGRIFDRFYRADPSRSSASG 417 ++NAIRYT + + + A + AT+++VSNPG I + R+FDRFYRADP+RS ++ Sbjct: 294 VANAIRYTAAGQTVVLAAAQTEQATVISVSNPGPQIADSAIPRLFDRFYRADPARSDSAS 353 Query: 418 SSGLGLAIVRSIMMLHGGEATVKSTQGERTIFSLTF 453 S+GLGLAIV+SIM LHGG + + + T+F+L F Sbjct: 354 SAGLGLAIVQSIMKLHGGRVELSRSAEQMTVFTLYF 389 >ref|ZP_08273803.1| Signal transduction histidine kinase [Oxalobacteraceae bacterium IMCC9480] gb|EGF32725.1| Signal transduction histidine kinase [Oxalobacteraceae bacterium IMCC9480] Length = 495 Score = 353 bits (905), Expect = 5e-95, Method: Composition-based stats. Identities = 206/458 (44%), Positives = 293/458 (63%), Gaps = 5/458 (1%) Query: 1 MTTRLVALFALVAIVTFAAVGTYLYHSLYVQLERRDDEELIGKIRSIDHLIQEAQSIDSI 60 +T RL LFA+ I TFA VGTYLY +L QL+ RDD ELI K + I +L++E+ SI +I Sbjct: 9 LTARLAILFAVATIATFALVGTYLYKALATQLQHRDDMELISKSQQIRYLLRESTSIAAI 68 Query: 61 KANNHAMLDTISGHDQLLMLITDASGVAILKNYSGPVELRT-SLFSTLQATQTNALQSID 119 + L+ + G D++ + + G I+++ + L + L + + S D Sbjct: 69 RQEPQRFLNAMYGQDEIRLQLLQTDGQLIMQSGAPSHALPSLPLVPATRHALEKDVSSWD 128 Query: 120 WEGNRIRFIASSPTTSAG--EKTRVIVARTVSDRMVLLADYRTEVWYAATIGTLLATLLS 177 R IAS+ E +++AR + R ++ Y + A +G +LA +L Sbjct: 129 SGAGTGRVIASAGMVGMDGLEPVHIVIAREGASRSAMMRKYGETLAVAVWLGAMLAAMLG 188 Query: 178 LFLVRSGLRPLRLMAAQTHAVSASRLDTRLDIRSAPKELHEIVESFNAMLDRLHRSFEQL 237 +V+ GLRPLRL+ Q +A+S RL TRL + P+ELHE+ ++FNAMLDRL ++L Sbjct: 189 FLVVQLGLRPLRLIITQANAISTQRLHTRLSNDNTPRELHELGQAFNAMLDRLEDGVKRL 248 Query: 238 TQFSADLAHDLRTPLNNLMVQTQVALGKPRSLEEYQGLLSSNIEEYERLARMMESMLFLA 297 TQF++D+AHDLRTP+N LMV+TQVAL K RS EEYQ LL SN+EEYERLAR++E+ LFLA Sbjct: 249 TQFASDIAHDLRTPVNTLMVETQVALTKERSNEEYQILLGSNLEEYERLARIIENTLFLA 308 Query: 298 RAENAHVAVKPQMLSVEDELAKIADYFEGIAEEADVRIVVSGTG-DIFADPMLLRRALGN 356 RA+NA +A++ + L + EL +I DYFEG+AE+A VR+ ++ I ADP+L RRA+ N Sbjct: 309 RADNAQLAMQSKTLDLAVELERIRDYFEGLAEDAGVRLTIAAAALTIEADPILFRRAVSN 368 Query: 357 LISNAIRYTPKERIIRVEATD-LDDATILTVSNPGEGIPPDVVGRIFDRFYRADPSRSSA 415 L+SNAI +TP+ I + AT + T +TV N G GIP + + IF+RFYR D +R+ + Sbjct: 369 LVSNAIVHTPRGSFIHLSATTAAGNKTRVTVENGGPGIPAEHLPHIFERFYRGDAARAPS 428 Query: 416 SGSSGLGLAIVRSIMMLHGGEATVKSTQGERTIFSLTF 453 S+GLGLAIV +IM LHGG+A V S GE+T+F L F Sbjct: 429 MYSAGLGLAIVCAIMRLHGGDAGVTSVAGEKTVFYLCF 466 >ref|YP_841161.1| signal transduction histidine kinase [Ralstonia eutropha H16] emb|CAJ96431.1| signal transduction histidine kinase [Ralstonia eutropha H16] Length = 485 Score = 333 bits (854), Expect = 4e-89, Method: Composition-based stats. Identities = 203/462 (43%), Positives = 286/462 (61%), Gaps = 12/462 (2%) Query: 1 MTTRLVALFALVAIVTFAAVGTYLYHSLYVQLERRDDEELIGKIRSIDHLIQEAQSIDSI 60 +TTRL + L V A+V YL +L QLE RD+ EL+G++ + HL++E +S I Sbjct: 8 LTTRLALAYGLATAVILASVAAYLSGALSAQLEGRDESELVGEVLLVRHLLREVRSEAEI 67 Query: 61 KANNHAMLDTISGHDQLLMLITDASGVAIL----KNYSGPVELRTSLFSTLQATQTNALQ 116 +A+ H D GH+ L++++ G ++ +N S P LR L +T Q ++ Sbjct: 68 RADTHRFADIAMGHEGLILVVRSRQGEPLVTLNPRNESVP-PLRV-LPATTQPEKSMLQT 125 Query: 117 SIDWEGNRIRFIASSPTTSAGEKT-RVIVARTVSDRMVLLADYRTEVWYAATIGTLLATL 175 G R IA+ +K ++V R R+ L+ DYR +V +A G +A Sbjct: 126 WYPKNGVPSRGIAALGQLGDSDKAVEIVVLRDAGYRVALIRDYRHQVLWATLCGAAVAAG 185 Query: 176 LSLFLVRSGLRPLRLMAAQTHAVSASRLDTRLDIRSAPKELHEIVESFNAMLDRLHRSFE 235 L L R GLRPLR MAA AV+ SRL TRLD+ SAP EL E+ + N ML RL SF Sbjct: 186 LGFVLARRGLRPLRRMAADAAAVTTSRLATRLDVGSAPAELRELAAALNDMLARLQDSFS 245 Query: 236 QLTQFSADLAHDLRTPLNNLMVQTQVALGKPRSLEEYQGLLSSNIEEYERLARMMESMLF 295 +L++FSADLAHD RTP++NL+ QTQV L + R + EY+ LL SN+EEYERLARM+E+MLF Sbjct: 246 RLSEFSADLAHDFRTPISNLIGQTQVTLAQSRGVAEYEALLESNLEEYERLARMIENMLF 305 Query: 296 LARAENAHVAVKPQMLSVEDELAKIADYFEGIAEEADVRIVVSGTGDIFADPMLLRRALG 355 LARA++A VA+ + L +EL K+A+YF+ +A + +V + V+GT + AD LLRRA+ Sbjct: 306 LARADHAQVALGIRTLDAREELDKMAEYFDAVAADREVALTVTGTAMVQADQTLLRRAVT 365 Query: 356 NLISNAIRYTPKERIIRVEA----TDLDDATILTVSNPGEGIPPDVVGRIFDRFYRADPS 411 NL+ NA+R+ P +R++ + L V+N G IPP+ + IF RFYRADPS Sbjct: 366 NLLDNALRHAPAGSTVRLDVERAPAPVSGTACLRVTNAGPAIPPETLPHIFGRFYRADPS 425 Query: 412 RSSASGSSGLGLAIVRSIMMLHGGEATVKSTQGERTIFSLTF 453 R +++ S+GLGLAIV +IM LHGG TV+S +GE T+FSL F Sbjct: 426 RRNSAASTGLGLAIVDTIMRLHGGSVTVRSVEGE-TMFSLQF 466