BLASTP 2.2.17 [Aug-26-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= 0001.1739.p (430 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_001353411.1| sensor kinase of copper sensing two-componen... 463 e-128 ref|YP_001099844.1| sensor kinase CopS like [Herminiimonas arsen... 453 e-125 ref|YP_296696.1| heavy metal sensor signal transduction histidin... 420 e-115 ref|YP_001899311.1| heavy metal sensor signal transduction histi... 412 e-113 ref|YP_002008601.1| sensory histidine kinase in two-component re... 404 e-110 >ref|YP_001353411.1| sensor kinase of copper sensing two-component system [Janthinobacterium sp. Marseille] gb|ABR91572.1| sensor kinase of copper sensing two-component system [Janthinobacterium sp. Marseille] Length = 458 Score = 463 bits (1191), Expect = e-128, Method: Composition-based stats. Identities = 248/424 (58%), Positives = 318/424 (75%), Gaps = 1/424 (0%) Query: 2 STVAKHFTDQDEQLLEKELELIRMVVNERGAGAITSTFGEALHNHPGFFVHISSIDGRPM 61 S + +HF +QD+ LL+ EL+LI+ V+ E+G +I+ TFGEALHNHP F+V + IDG+ + Sbjct: 31 SAIEEHFAEQDQLLLQNELQLIQKVIKEKGIDSISQTFGEALHNHPDFYVDVRDIDGKEI 90 Query: 62 YSTLADATQPILAAAKRVASGHSFAVNAGQHQEFQAIKAYLKDDKSSEQLQVIVAVDTEI 121 YSTL IL+ + + + F V H+EFQAI+A LK S + V++AVD I Sbjct: 91 YSTLGPFRDAILSREPNIETENDFDVRIDAHREFQAIRAELKASVGSPVI-VVIAVDKAI 149 Query: 122 HDHFMRNFQTTLILYVAGSAVIVVLLSWWAARRGLAPLRAMSDKVQAVSSHNFGERMPIE 181 H HFM F+TTL+LY+ +A+ ++L WWAAR+GL+PLR M+ + QAV+S N ERMP++ Sbjct: 150 HTHFMSMFRTTLMLYILVAAMATIMLGWWAARQGLSPLRTMAARAQAVTSQNMKERMPVD 209 Query: 182 TLPVEIADLAAKLNAMLERLQQDFHRITNFSTDIAHELRTPITNLLTQTDVVLTQQRTNE 241 +P E+ DLA KLNAML+RLQ D R+T FS D+AHELRTPI+N+LTQT VVL Q R+ Sbjct: 210 AVPTEMTDLAVKLNAMLDRLQNDIARLTEFSADLAHELRTPISNMLTQTHVVLNQSRSAA 269 Query: 242 AYRDTLSSNAEELQRLARTISDMLFLAQTENGISLPSYEPLKLQDEITELLDFYDALAEE 301 YRD+LSSNAEELQRL +TISDMLFLAQTENG++LPS E L + E LL+FY+ALAEE Sbjct: 270 DYRDSLSSNAEELQRLGKTISDMLFLAQTENGLALPSVEKLNMAQECQALLEFYEALAEE 329 Query: 302 KGVNLQLTGDAIVRGDRLMVRRALSNLISNAMRYTPASGSIAVSIARSEDGILVTVENDG 361 K V L+ GDA+V GDRLM RRAL+NL+SNA+RYTP+ G+I++ I ++ G +VTVENDG Sbjct: 330 KEVTLRCEGDAVVIGDRLMFRRALNNLLSNALRYTPSHGTISIKIKAAQAGTVVTVENDG 389 Query: 362 PEIPPEHLPHLFDRFYRADKSRTKLDTDSAGLGLSITQAIMRAHQGSVSVRSALGKTRFT 421 EIP E PHLFDRFYRADKSR K ++DSAGLGLSIT+AIM+AH GSVSV S KT F+ Sbjct: 390 KEIPIEIQPHLFDRFYRADKSRKKSESDSAGLGLSITRAIMQAHGGSVSVVSGESKTAFS 449 Query: 422 LNFP 425 L FP Sbjct: 450 LYFP 453 >ref|YP_001099844.1| sensor kinase CopS like [Herminiimonas arsenicoxydans] emb|CAL61717.1| Sensor kinase CusS [Herminiimonas arsenicoxydans] Length = 458 Score = 453 bits (1165), Expect = e-125, Method: Composition-based stats. Identities = 242/424 (57%), Positives = 314/424 (74%), Gaps = 1/424 (0%) Query: 2 STVAKHFTDQDEQLLEKELELIRMVVNERGAGAITSTFGEALHNHPGFFVHISSIDGRPM 61 S + +HF++QD+ LL+ EL+LI+ V+ E+G +I+ TFGEALHNHP F+V + ++G+ + Sbjct: 31 SAIEEHFSEQDQLLLQNELQLIQKVIEEKGVDSISQTFGEALHNHPDFYVDVRDLNGKEI 90 Query: 62 YSTLADATQPILAAAKRVASGHSFAVNAGQHQEFQAIKAYLKDDKSSEQLQVIVAVDTEI 121 YST IL+ + + F V +H+EFQAI+A LK S + V++AVD I Sbjct: 91 YSTFGAFRDAILSRIPSSKTKNGFDVKIDEHREFQAIRAELKASAGSPVI-VVIAVDKAI 149 Query: 122 HDHFMRNFQTTLILYVAGSAVIVVLLSWWAARRGLAPLRAMSDKVQAVSSHNFGERMPIE 181 H HFM F+TTL+LYV +A+ V+L WWAAR+GL+PLR M+ + Q V+S N ERMP++ Sbjct: 150 HTHFMSMFRTTLMLYVMVAAIATVMLGWWAARQGLSPLRTMAARAQTVTSQNMNERMPVD 209 Query: 182 TLPVEIADLAAKLNAMLERLQQDFHRITNFSTDIAHELRTPITNLLTQTDVVLTQQRTNE 241 +P E+ DLA KLNAML+RLQ D R+T FS D+AHELRTPI+N+LTQT VVL Q R+ Sbjct: 210 AVPTEMTDLAVKLNAMLDRLQNDIARLTEFSADLAHELRTPISNMLTQTHVVLNQSRSTA 269 Query: 242 AYRDTLSSNAEELQRLARTISDMLFLAQTENGISLPSYEPLKLQDEITELLDFYDALAEE 301 YRD+LSSNAEELQRL TISDMLFLAQTENG++LPS L + E LL+FY+ALAEE Sbjct: 270 DYRDSLSSNAEELQRLGNTISDMLFLAQTENGLALPSVAKLNMARECQALLEFYEALAEE 329 Query: 302 KGVNLQLTGDAIVRGDRLMVRRALSNLISNAMRYTPASGSIAVSIARSEDGILVTVENDG 361 K V L+ GDA+V GD+LM RRAL+NL+SNA+RYTP+ G+I++ I +E G +TV+NDG Sbjct: 330 KKVVLRCEGDAVVIGDQLMFRRALNNLLSNAIRYTPSYGTISIKITSAESGTTITVQNDG 389 Query: 362 PEIPPEHLPHLFDRFYRADKSRTKLDTDSAGLGLSITQAIMRAHQGSVSVRSALGKTRFT 421 EIP E PHLFDRF+RADKSR K ++DSAGLGLSIT+AIM+AH GSVSV S KT F+ Sbjct: 390 EEIPAEIQPHLFDRFFRADKSRKKSESDSAGLGLSITRAIMQAHGGSVSVVSRDSKTAFS 449 Query: 422 LNFP 425 L FP Sbjct: 450 LYFP 453 >ref|YP_296696.1| heavy metal sensor signal transduction histidine kinase [Ralstonia eutropha JMP134] gb|AAZ61852.1| heavy metal sensor signal transduction histidine kinase [Ralstonia eutropha JMP134] Length = 465 Score = 420 bits (1079), Expect = e-115, Method: Composition-based stats. Identities = 216/426 (50%), Positives = 297/426 (69%), Gaps = 1/426 (0%) Query: 2 STVAKHFTDQDEQLLEKELELIRMVVNERGAGAITSTFGEALHNHPGFFVHISSIDGRPM 61 + + +HF ++D L + LI + E A +++ AL +HPGF H+S+ DG + Sbjct: 31 TAMDQHFAEEDFASLGDNVRLIERIATENAAASVSERLAVALEHHPGFIAHVSAADGTLL 90 Query: 62 YSTLADATQPILAAAKRVASGHSFAVNAGQHQEFQAIKAYLKDDKSSE-QLQVIVAVDTE 120 Y++ + +L A + +G + ++ ++A ++ + L ++V +DTE Sbjct: 91 YASNGFDFRTVLGTASVLPAGRESFDWEQDGKSYRGMRATVQATGDKQVPLTIVVGMDTE 150 Query: 121 IHDHFMRNFQTTLILYVAGSAVIVVLLSWWAARRGLAPLRAMSDKVQAVSSHNFGERMPI 180 IH HFMR F+ +L YV +A+ LL WWAARRGLAPLR M+ + +AV++H RMP+ Sbjct: 151 IHAHFMRAFRRSLTFYVTLAALASGLLGWWAARRGLAPLRTMASRARAVTAHKLDARMPV 210 Query: 181 ETLPVEIADLAAKLNAMLERLQQDFHRITNFSTDIAHELRTPITNLLTQTDVVLTQQRTN 240 + +PVE+ADLA LNAMLERLQ DF R+++FS+DIAHELRTP+TNL+TQT VVL+Q R Sbjct: 211 DAVPVEMADLAGTLNAMLERLQSDFQRLSDFSSDIAHELRTPLTNLMTQTHVVLSQPRAA 270 Query: 241 EAYRDTLSSNAEELQRLARTISDMLFLAQTENGISLPSYEPLKLQDEITELLDFYDALAE 300 E YRD L+SNAEELQRL+R +SDML+LAQ E+G++LPS EP+ + E+ L +FYDALAE Sbjct: 271 EKYRDVLASNAEELQRLSRMVSDMLYLAQMEHGLTLPSAEPIDVAVEVHALFEFYDALAE 330 Query: 301 EKGVNLQLTGDAIVRGDRLMVRRALSNLISNAMRYTPASGSIAVSIARSEDGILVTVEND 360 +K V LQL G+ + GDRLM+RRALSNL+SNA+RYTP G I + I S D I V+VEND Sbjct: 331 DKAVRLQLRGEGHIVGDRLMLRRALSNLLSNALRYTPPGGVIVIEIGGSADTITVSVEND 390 Query: 361 GPEIPPEHLPHLFDRFYRADKSRTKLDTDSAGLGLSITQAIMRAHQGSVSVRSALGKTRF 420 G +I P+ LP +FDRF R DKSR + ++DS GLGLSIT+AIM AH G+++V+SA GKTRF Sbjct: 391 GQDIRPDLLPVIFDRFSRGDKSRVRPESDSVGLGLSITRAIMAAHGGTIAVQSASGKTRF 450 Query: 421 TLNFPR 426 TL F R Sbjct: 451 TLAFRR 456 >ref|YP_001899311.1| heavy metal sensor signal transduction histidine kinase [Ralstonia pickettii 12J] gb|ACD26879.1| heavy metal sensor signal transduction histidine kinase [Ralstonia pickettii 12J] Length = 461 Score = 412 bits (1058), Expect = e-113, Method: Composition-based stats. Identities = 213/424 (50%), Positives = 285/424 (67%) Query: 3 TVAKHFTDQDEQLLEKELELIRMVVNERGAGAITSTFGEALHNHPGFFVHISSIDGRPMY 62 ++ +HF D+D +L + LI+ + E+ + + S E + +HPGF H+S+ G +Y Sbjct: 33 SMDRHFADEDYVVLGDNVRLIQKIAQEQSSTHLPSRLAEMVEHHPGFVAHVSTAKGDVIY 92 Query: 63 STLADATQPILAAAKRVASGHSFAVNAGQHQEFQAIKAYLKDDKSSEQLQVIVAVDTEIH 122 T +L R+ + +E++ ++A+ S L V+V +DTEIH Sbjct: 93 RTNGFDFGAMLNVIGRLGPDETTLSWQQGDKEYRGMRAHATVPGESVPLAVMVGMDTEIH 152 Query: 123 DHFMRNFQTTLILYVAGSAVIVVLLSWWAARRGLAPLRAMSDKVQAVSSHNFGERMPIET 182 HFM F+ +L Y + + L WWAARRGLAPLR M+ + + V+S++ RMP+ET Sbjct: 153 AHFMHAFRRSLAFYTTLAVLASGLFGWWAARRGLAPLRTMASRAKGVTSNHLDARMPVET 212 Query: 183 LPVEIADLAAKLNAMLERLQQDFHRITNFSTDIAHELRTPITNLLTQTDVVLTQQRTNEA 242 +PVE+ADLAA LNAMLERLQ DF R++ FS+D+AHELRTPITNL+TQT VVL+Q R Sbjct: 213 VPVEMADLAATLNAMLERLQDDFRRLSEFSSDLAHELRTPITNLMTQTHVVLSQPREAAK 272 Query: 243 YRDTLSSNAEELQRLARTISDMLFLAQTENGISLPSYEPLKLQDEITELLDFYDALAEEK 302 YRD L+SNAEEL RL R +SDML+LA+ E+GI+LP+ E + + DE L DFYDALAE+K Sbjct: 273 YRDVLASNAEELLRLGRMVSDMLYLAKMEHGITLPNEESIHVGDEARALFDFYDALAEDK 332 Query: 303 GVNLQLTGDAIVRGDRLMVRRALSNLISNAMRYTPASGSIAVSIARSEDGILVTVENDGP 362 GV L+L GDA + GDRLM+RRALSNL+SNA+RYTP+ +I + + G + VEN G Sbjct: 333 GVQLRLQGDASIVGDRLMLRRALSNLLSNALRYTPSGKAIVIKACEQDGGATIVVENQGE 392 Query: 363 EIPPEHLPHLFDRFYRADKSRTKLDTDSAGLGLSITQAIMRAHQGSVSVRSALGKTRFTL 422 I PE LP LFDRF+RADKSR + D+DS GLGLSITQAIM AH+G +S S+ G TRF L Sbjct: 393 GIDPELLPSLFDRFFRADKSRARADSDSVGLGLSITQAIMVAHRGGISAESSGGLTRFIL 452 Query: 423 NFPR 426 FPR Sbjct: 453 TFPR 456 >ref|YP_002008601.1| sensory histidine kinase in two-component regulatory system with copr, regulation of copper resistance, senses copper ions [Cupriavidus taiwanensis LMG 19424] emb|CAQ72549.1| sensory histidine kinase in two-component regulatory system with CopR, regulation of copper resistance, senses copper ions [Cupriavidus taiwanensis LMG 19424] Length = 465 Score = 404 bits (1039), Expect = e-110, Method: Composition-based stats. Identities = 224/430 (52%), Positives = 294/430 (68%), Gaps = 9/430 (2%) Query: 4 VAKHFTDQDEQLLEKELELIRMVVNERGAGAITSTFGEALHNHPGFFVHISSIDGRPMYS 63 + HF D+D +L + LI + + ++ G AL +H GF + DG+ +Y+ Sbjct: 34 IDDHFADEDYAVLADNVRLIGKIAADGPPASLPQRLGPALEHHAGFVAEVRGADGKRLYA 93 Query: 64 TLADATQPILAAAKRVASGHSFAVNAGQHQEFQAIKAYLK----DDKSSEQ---LQVIVA 116 T + LAAA + +G Q Q ++ ++A L D +S Q LQV+V Sbjct: 94 TRDFDFRTALAAAAQAPAGRDAFAWEQQGQTYRGLRAQLAVAPADARSGGQPGALQVLVG 153 Query: 117 VDTEIHDHFMRNFQTTLILYVAGSAVIVVLLSWWAARRGLAPLRAMSDKVQAVSSHNFGE 176 +DT +HDHFM F+ TL Y A +A+ LL WWAARRGL+PLR M+ + +AV++H E Sbjct: 154 MDTALHDHFMHAFRNTLAFYGALAALASGLLGWWAARRGLSPLRTMASRARAVTAHKLDE 213 Query: 177 RMPIETLPVEIADLAAKLNAMLERLQQDFHRITNFSTDIAHELRTPITNLLTQTDVVLTQ 236 RMP+ET+PVE+ADLAA LNAMLERLQ+DF R++ FS+D+AHELRTPITNL+TQT VVL+Q Sbjct: 214 RMPVETVPVEMADLAANLNAMLERLQRDFARLSEFSSDLAHELRTPITNLMTQTQVVLSQ 273 Query: 237 QRTNEAYRDTLSSNAEELQRLARTISDMLFLAQTENGISLPSYEPLKLQDEITELLDFYD 296 R YRD L+SN EELQRL+R +SDML+LA+TE+GI+LPS EP+++ DE+ L DFYD Sbjct: 274 PRDAARYRDVLASNVEELQRLSRMVSDMLYLAKTEHGITLPSAEPIEVADEVAALFDFYD 333 Query: 297 ALAEEKGVNLQLTGDAIVRGDRLMVRRALSNLISNAMRYTPASGSIAVSIARSEDGILVT 356 ALAE+KGV L L G + GDRLM+RRALSNL+SNA+R+TPA I V I D + V Sbjct: 334 ALAEDKGVRLALRGRGRITGDRLMLRRALSNLLSNALRHTPAGKGIVVEITPGADAVQVV 393 Query: 357 VENDGPEIPPEHLPHLFDRFYRADKSRTKLDTDSA--GLGLSITQAIMRAHQGSVSVRSA 414 VEN+G I PE LP LFDRF+RADKSR + ++D A GLGL+ITQAI+ AH G++ V S Sbjct: 394 VENEGETIRPELLPVLFDRFFRADKSRARPESDGAGLGLGLAITQAIVAAHGGAIGVASE 453 Query: 415 LGKTRFTLNF 424 GKTRFTL F Sbjct: 454 AGKTRFTLTF 463