BLASTP 2.2.17 [Aug-26-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= 0001.1485.p (561 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003775519.1| signal transduction histidine kinase [Herbas... 887 0.0 ref|YP_004752956.1| putative diguanylate cyclase (GGDEF domain) ... 497 e-138 ref|YP_003169078.1| diguanylate cyclase [Candidatus Accumulibact... 301 1e-79 ref|ZP_03541507.1| diguanylate cyclase [Comamonas testosteroni K... 284 3e-74 ref|YP_003279891.1| diguanylate cyclase [Comamonas testosteroni ... 280 5e-73 >ref|YP_003775519.1| signal transduction histidine kinase [Herbaspirillum seropedicae SmR1] gb|ADJ63611.1| signal transduction histidine kinase protein [Herbaspirillum seropedicae SmR1] Length = 560 Score = 887 bits (2292), Expect = 0.0, Method: Composition-based stats. Identities = 444/561 (79%), Positives = 489/561 (87%), Gaps = 1/561 (0%) Query: 1 MFCLMLTIGWFLYRAGDDATEVLARNALTEVMGRVSQAIDRQTQGARETLNVIAPRPVPP 60 M CL+LTIGWFLYRAGDDATEVLARNALTE++GRVSQAIDRQT GARE+LNV+AP V Sbjct: 1 MVCLVLTIGWFLYRAGDDATEVLARNALTELIGRVSQAIDRQTMGARESLNVVAPPAVRT 60 Query: 61 VEVGQAPALLPFPKSRKELEDRLWLANSLFDEPSYVYFGGVDGSFLGIKQEQPQVFMYSV 120 GQ PA+LPFP KELE+RLWLAN +F++PSYVYFGG DGSFLGIKQE+ F YSV Sbjct: 61 AAPGQPPAMLPFPVHSKELEERLWLANLMFEDPSYVYFGGADGSFLGIKQEEGSQFTYSV 120 Query: 121 REPGQKNFVYYLRGPGTEMKLTAVQDYEPRKRPWYLQAVKQGHETWSPVYIDYRVKNIVG 180 REP KN+VY LRGPGT M+L A Q+YEPRKRPWY+QAV++G ETWS VY DYR K++ G Sbjct: 121 REPDGKNYVYQLRGPGTPMELVAAQEYEPRKRPWYVQAVQRGRETWSSVYADYRQKHL-G 179 Query: 181 INLSKPIFDADGTLLGVANSSIGLQQLGALLRQVPLSAQGVAFVTEMKGDMVATSLDEPI 240 INLSKPIFDADG LLGVANSSIGL +L LLR +PL A GVAFVTE+ GDM+A S++EP+ Sbjct: 180 INLSKPIFDADGKLLGVANSSIGLLRLTTLLRALPLGAHGVAFVTELNGDMIADSVNEPL 239 Query: 241 YQAGENGGEPRRLNAGQSKSPLVRQAFAEVQRYLGTHPPEPDKLILLGSRSEGSKIEVAF 300 +Q + + RRLNA QS SPLVRQA+ EV+RYL P + KL+LL SR+EG KIEVAF Sbjct: 240 HQIRDQDPDLRRLNASQSSSPLVRQAYEEVRRYLARQPAQSGKLMLLSSRTEGGKIEVAF 299 Query: 301 RLYRDPAGLAWLSISAAPRSDFLGSVTSGVYQTLTLGLMAVCLTFVIGFLLLRWVLRDIR 360 RL+ D AGL WL+ISAAPRSDFLGSVTSGVYQTL LGLMAVCLTFVIGFLLLRWVLRDIR Sbjct: 300 RLHHDAAGLDWLAISAAPRSDFLGSVTSGVYQTLMLGLMAVCLTFVIGFLLLRWVLRDIR 359 Query: 361 KLTLAAKSIGNGSPFPDLNIDRNDEIGQLAQSFVEMERNLRTDRLTNVLNRDSLIAQIDF 420 +LT AAKSIGNGSPFPDLNI+RNDEIGQLAQSFVEMERNLRTDRLTNVLNRDSLIAQIDF Sbjct: 360 RLTQAAKSIGNGSPFPDLNINRNDEIGQLAQSFVEMERNLRTDRLTNVLNRDSLIAQIDF 419 Query: 421 RRRNSSQAVPLHFALLFIDLDRFKAVNDEYGHDEGDKVLIAIAERLQHSLRHDDSVARFG 480 RR N PLHF LLFIDLDRFKAVNDEYGHDEGDKVL+ IA+RLQH+LRHDDSVARFG Sbjct: 420 RRSNCVDGSPLHFGLLFIDLDRFKAVNDEYGHDEGDKVLVTIAQRLQHTLRHDDSVARFG 479 Query: 481 GDEFVVYLHGVTEMDVARSIADKIRHAVNKPIAGRDGQDYTVDASVGVSLYPDDGLDVET 540 GDEFVVYLHGV++M+VARSIADKIRHAVNKPI GR+GQ Y VDASVGVSLYPDDGLDVET Sbjct: 480 GDEFVVYLHGVSDMEVARSIADKIRHAVNKPIPGREGQQYVVDASVGVSLYPDDGLDVET 539 Query: 541 LLRVADSRMFDQKRLHRILSV 561 LLRVADSRMFDQKRLHRILSV Sbjct: 540 LLRVADSRMFDQKRLHRILSV 560 >ref|YP_004752956.1| putative diguanylate cyclase (GGDEF domain) [Collimonas fungivorans Ter331] gb|AEK62133.1| Putative diguanylate cyclase (GGDEF domain) [Collimonas fungivorans Ter331] Length = 634 Score = 497 bits (1280), Expect = e-138, Method: Composition-based stats. Identities = 271/575 (47%), Positives = 372/575 (64%), Gaps = 23/575 (4%) Query: 1 MFCLMLTIGWFLYRAGDDATEVLARNALTEVMGRVSQAIDRQTQGARETLNVIAPRPVPP 60 + CL +++GW LY+ G DAT+ L++ L ++MG + AI+RQ A L V+AP V Sbjct: 54 LLCLAVSVGWLLYQTGQDATDALSQKVLADMMGGIDSAINRQLFDAGAALRVVAPDQVAG 113 Query: 61 VEVGQAPALLPFPKSRKELEDRLWLANSLFDE-PSYVYFGGVDGSFLGIKQEQPQVFMYS 119 ++P +PFP S LE+R+W+A+ LF S + F GVDG ++GI++ F Sbjct: 114 A-ANKSPTPIPFPASIGRLEERMWIASGLFPTIGSVISFAGVDGHYVGIRRTAANEFRVR 172 Query: 120 VREPGQ-KNFVYYLRGPGTEMKLTAVQDYEPRKRPWYLQAVKQGHETWSPVYIDYRVKNI 178 +R G+ +Y RGP TE L ++YEPR++ WYL AV Q + WSPV+ID Sbjct: 173 LRGAGEGPTHLYRSRGPATEKILLETENYEPREQSWYLNAVSQRKDIWSPVFIDASSSEP 232 Query: 179 VGINLSKPIFDADGTLLGVANSSIGLQQLGALLRQVPLSAQGVAFVTEMKGDMVATSLDE 238 V + L++P++D + +LGV + L L L+ +P+ GVAFV E GD+V S E Sbjct: 233 V-LMLARPVYDGEQEVLGVVARELSLWPLREYLQALPMDKNGVAFVAEPNGDLVIASNGE 291 Query: 239 PIYQAGENGGEPR--RLNAGQSKSPLVRQAFAEVQRYLGTH----------------PPE 280 + A NG + + R N +P +RQ++ VQ YL H PP+ Sbjct: 292 GAF-APRNGAQNQHIRNNLKDVAAPFMRQSWQLVQNYLQKHRETAPVTDPIAASAASPPK 350 Query: 281 PDKLILLGSRSEGSKIEVAFRLYRDPAGLAWLSISAAPRSDFLGSVTSGVYQTLTLGLMA 340 P KLI+ S+ +IEVA +++RD AGL W+++ A PRSDF G+V S VY++L LGL+ Sbjct: 351 PGKLIVGAFPSKYGQIEVAAQIHRDAAGLEWVAVVALPRSDFWGAVNSSVYKSLYLGLLV 410 Query: 341 VCLTFVIGFLLLRWVLRDIRKLTLAAKSIGNGSPFPDLNIDRNDEIGQLAQSFVEMERNL 400 + L + G+ +LRWVLRDIRKLTLA +SIG+G PF LNIDR DEIG+LAQSF EMERNL Sbjct: 411 ILLALLFGYAILRWVLRDIRKLTLAVRSIGSGRPFAKLNIDRKDEIGELAQSFQEMERNL 470 Query: 401 RTDRLTNVLNRDSLIAQIDFRRRNSSQAVPLHFALLFIDLDRFKAVNDEYGHDEGDKVLI 460 RTDRLT++LNRDSLIAQI+FRRR + FA+LF+DLD+FK VND YGHDEGD+VLI Sbjct: 471 RTDRLTSLLNRDSLIAQIEFRRRTDVEPHLFRFAVLFVDLDKFKQVNDHYGHDEGDRVLI 530 Query: 461 AIAERLQHSLRHDDSVARFGGDEFVVYLHGVTEMDVARSIADKIRHAVNKPIAGRDGQDY 520 + RLQ++LR +D VARFGGDEF+VYL GV + + A +IA+KI +NKPI +G+ Sbjct: 531 EVGLRLQNTLRKEDEVARFGGDEFIVYLPGVADEESALAIAEKIYAVLNKPILMANGEHC 590 Query: 521 TVDASVGVSLYPDDGLDVETLLRVADSRMFDQKRL 555 + AS+G +LYP DGLD+ETLL+VAD RM+ K+ Sbjct: 591 QIGASIGGALYPADGLDLETLLKVADKRMYSVKKF 625 >ref|YP_003169078.1| diguanylate cyclase [Candidatus Accumulibacter phosphatis clade IIA str. UW-1] gb|ACV37149.1| diguanylate cyclase [Candidatus Accumulibacter phosphatis clade IIA str. UW-1] Length = 573 Score = 301 bits (772), Expect = 1e-79, Method: Composition-based stats. Identities = 191/559 (34%), Positives = 299/559 (53%), Gaps = 20/559 (3%) Query: 4 LMLTIGWFLYRAGDDATEVLARNALTEVMGRVSQAIDRQTQGARETLNVIAPRPVP-PVE 62 L IG Y AG A + L+ L+E++ R++QA +R GA L P V P Sbjct: 13 LAAAIGGLSYSAGRVAVDTLSNQLLSEMVYRIAQAAERHVFGASAVLETAFPSGVAAPEH 72 Query: 63 VGQAPALLPFPKSRKELEDRLWLANSLFDEPS-YVYFGGVDGSFLGIKQEQPQVFMYSVR 121 +G L R WLA S+ +P+ Y Y+G +G F G+ + +R Sbjct: 73 IG---------ADLDNLRTRFWLATSVHRDPNHYAYYGDRNGEFFGLWRHSETEAELRLR 123 Query: 122 EPGQ-KNFVYYLRGPGTEMK--LTAVQDYEPRKRPWYLQAVKQGHETWSPVYIDYRVKNI 178 G+ +Y G E++ ++ + +EPR+RPW+ TW+ VYID++ + + Sbjct: 124 TSGKGPRRIYRFSGIAGELREPVSETRVFEPRERPWFKSGQSSALHTWTSVYIDFKTEEL 183 Query: 179 VGINLSKPIFDADGTLLGVANSSIGLQQLGALLRQVPLSAQGVAFVTEMKGDMVATSLDE 238 V ++ + +A G GV + + LQQ+ LR + L+A G+A+V E G+++ TS Sbjct: 184 VATR-ARRVNNALGEFQGVVATDLSLQQVNQFLRSLKLTANGIAYVVEPDGNLIGTSRGP 242 Query: 239 PIYQAGENGGEPRRLNAGQSKSPLVRQAFAEVQRYLGTHPPEPDKLILLGSRSEGSKIEV 298 + + G RLNA S PLV ++ E+++ L + + ++ +E Sbjct: 243 HLRKDAAGGNA--RLNAEASADPLVVDSYREIRKLLPDSAAATHPRTAVFATADDQPVEA 300 Query: 299 AFRLYRDPAGLAWLSISAAPRSDFLGSVTSGVYQTLTLGLMAVCLTFVIGFLLLRWVLRD 358 A+ +D AGL W + A PRSDFLG VT + + L L+A +T VIG ++L V D Sbjct: 301 AYARLQDAAGLDWTIVIAVPRSDFLGGVTQSYQRNVGLALLASLMTVVIGLMVLSVVAGD 360 Query: 359 IRKLTLAAKSIGNGSPFPDLNIDRNDEIGQLAQSFVEMERNLRTDRLTNVLNRDSLIAQI 418 +++L AA+++G+G L++ R DEIG LA+SF M+ L +DRLT + NR++ + ++ Sbjct: 361 LKRLATAARNVGDGDFNATLDVTRRDEIGDLAKSFRAMQSKLLSDRLTGLANREAFLRRV 420 Query: 419 DFRR-RNSSQAVPLHFALLFIDLDRFKAVNDEYGHDEGDKVLIAIAERLQHSLRHDDSVA 477 D R + + A P FA+LFIDL+ FK +ND +GHD GDKVL A+R+ LR D VA Sbjct: 421 DDRLVQQHAVADPRPFAILFIDLNDFKHINDSFGHDVGDKVLQETAQRMLGGLRSRDMVA 480 Query: 478 RFGGDEFVVYLHGVTEMDVARSIADKIRHAVNKPI--AGRDGQDYTVDASVGVSLYPDDG 535 R+ GDEFVV L V A S K+ H + P+ A+VG+++YPDDG Sbjct: 481 RYAGDEFVVMLDAVHNRQDAESARSKLEHLLETPLLSLAPTATGARAGAAVGLAIYPDDG 540 Query: 536 LDVETLLRVADSRMFDQKR 554 DVE+LL+ +D+ M+ +K+ Sbjct: 541 QDVESLLQCSDADMYRRKQ 559 >ref|ZP_03541507.1| diguanylate cyclase [Comamonas testosteroni KF-1] gb|EED65793.1| diguanylate cyclase [Comamonas testosteroni KF-1] Length = 581 Score = 284 bits (727), Expect = 3e-74, Method: Composition-based stats. Identities = 185/563 (32%), Positives = 291/563 (51%), Gaps = 28/563 (4%) Query: 4 LMLTIGWFLYRAGDDATEVLARNALTEVMGRVSQAIDRQTQGARETLNVIAP--RPVPPV 61 L +G Y G +A L+ + E R++ +DR + L P VP Sbjct: 29 LTSALGMLWYWTGSNAVSALSEQVMEEKAERIALIVDRHLYPSSAVLEAAFPSGESVPAD 88 Query: 62 EVGQAPALLPFPKSRKELEDRLWLANSLFDEPS-YVYFGGVDGSFLGIKQEQPQVFMYSV 120 PAL+ RLW+A+SL +P+ YVY+ V G + +K+ P++ + Sbjct: 89 IRDHVPALI----------SRLWVASSLHTQPNDYVYYANVAGQGIALKRLTPELGQLRL 138 Query: 121 REPGQKNFVYY-LRGPGTE--MKLTAVQDYEPRKRPWYLQAVKQGHETWSPVYIDYRVKN 177 + ++ Y+ + G E + T + +EPR+RPW+ A + W+P YID+ K+ Sbjct: 139 KTRASEHRSYFKVAGMHAEPVYESTEINLFEPRQRPWFKLAAESADVIWTPAYIDFSAKD 198 Query: 178 IVGINLSKPIFDADGTLLGVANSSIGLQQLGALLRQVPLSAQGVAFVTEMKGDMVATSLD 237 +V + ++ I + G L GV + I L+ L + Q+ LS G AF+ E G ++A + Sbjct: 199 LV-LTRARRILSSKGRLEGVVATDISLRALNEFVNQLHLSEHGRAFIIEADGSLIAATGM 257 Query: 238 EPIYQAGENGGEPRRLNAGQSKSPLVRQAFAEVQRYLGTHPPEPDKLILLGSRSEGSKIE 297 I++ G+ R++A S+ PL++ + ++Q T L + S I Sbjct: 258 PNIHR--REDGQLERMSAANSQDPLIQAVYDKIQGAFQTSKSGAAPGTALLEDAGHSNIR 315 Query: 298 VAFRLYRDPAGLAWLSISAAPRSDFLGSVTSGVYQTLTLGLMAVCLTFVIGFLLLRWVLR 357 +A+R +G W+++ A P D L V + +LGL+A+ + VIG + V Sbjct: 316 IAYRRLNLGSGQDWMAVVAVPHKDMLTGVYRHMVLVGSLGLLALVVAVVIGTRIFGAVAN 375 Query: 358 DIRKLTLAAKSIGNGSPFPDLNIDRNDEIGQLAQSFVEMERNLRTDRLTNVLNRDSL--- 414 D+R LT A +S+G G + + R DEIG+LA +F M +L TD LT NR +L Sbjct: 376 DMRSLTRAVRSVGQGEIDTPIEVQRRDEIGELAHNFHRMRHSLFTDPLTGANNRSALQHI 435 Query: 415 IAQIDFRRRNSSQAVPLHFALLFIDLDRFKAVNDEYGHDEGDKVLIAIAERLQHSLRHDD 474 +A + S A P FALLF+DLDRFK +ND +GHD GD L I+ RL++ LR DD Sbjct: 436 LATLTRPLPGQSMAAP--FALLFVDLDRFKPLNDRWGHDNGDLALAEISLRLRNLLRPDD 493 Query: 475 SVARFGGDEFVVYLHGVTEMDVARSIADKIRHAVNKPIAG----RDGQDYTVDASVGVSL 530 VAR GGDEF++ L GV++ + +++ KI HA+ +P+ +G+ TV ASVG +L Sbjct: 494 VVARLGGDEFILILRGVSDEEQVQAVRLKIEHALQQPLTTLLGIPEGESVTVGASVGQAL 553 Query: 531 YPDDGLDVETLLRVADSRMFDQK 553 YP D D ++LL+VAD M+ K Sbjct: 554 YPRDAQDAQSLLKVADQDMYRNK 576 >ref|YP_003279891.1| diguanylate cyclase [Comamonas testosteroni CNB-2] gb|ACY34595.1| diguanylate cyclase [Comamonas testosteroni CNB-2] Length = 581 Score = 280 bits (716), Expect = 5e-73, Method: Composition-based stats. Identities = 180/560 (32%), Positives = 286/560 (51%), Gaps = 20/560 (3%) Query: 4 LMLTIGWFLYRAGDDATEVLARNALTEVMGRVSQAIDRQTQGARETLNVIAPRPVPPVEV 63 L +G Y G + L+ + E R++ +DR + L P Sbjct: 29 LTSALGMLWYWTGSNTVSALSEQVMQEKAERIALIVDRHLYPSSAVLEAAFPS------- 81 Query: 64 GQAPALLPFPKSRKELEDRLWLANSLFDEPS-YVYFGGVDGSFLGIKQEQPQVFMYSVR- 121 GQ P + +L RLW+A SL P+ YVY+ + G + +K+ P++ ++ Sbjct: 82 GQ-PVAADIREHIPDLISRLWVATSLHTRPNDYVYYANIAGQGIALKRVAPELGQLRLKT 140 Query: 122 EPGQKNFVYYLRGPGTE--MKLTAVQDYEPRKRPWYLQAVKQGHETWSPVYIDYRVKNIV 179 + G+ + + E + T +EPR+RPW+ A + W+P YID+ K++V Sbjct: 141 QSGEHRSYFKVASMHAEPIYESTETNLFEPRQRPWFKLAAESADVIWTPAYIDFSAKDLV 200 Query: 180 GINLSKPIFDADGTLLGVANSSIGLQQLGALLRQVPLSAQGVAFVTEMKGDMVATSLDEP 239 + ++ I + G+L GV + I L+ L + Q+ LS G AF+ E G ++A + Sbjct: 201 -LTRARRILSSKGSLEGVIATDISLRALNEFVNQLHLSEHGRAFIIEADGSLIAATGMPN 259 Query: 240 IYQAGENGGEPRRLNAGQSKSPLVRQAFAEVQRYLGTHPPEPDKLILLGSRSEGSKIEVA 299 I+Q N G+ R+ A S+ PL++ + ++Q + L + I +A Sbjct: 260 IHQ--RNDGKLERMTAANSQDPLIQAVYDKIQGAFQSSLSSDGPGTALLEDDRHNHIRIA 317 Query: 300 FRLYRDPAGLAWLSISAAPRSDFLGSVTSGVYQTLTLGLMAVCLTFVIGFLLLRWVLRDI 359 +R + AG W+++ A P D L V + +LGL+A+ + VIG + V D+ Sbjct: 318 YRRLSNGAGQDWMAVVAVPHKDMLAGVYRHMALVGSLGLLALVVAVVIGTRIFGAVANDM 377 Query: 360 RKLTLAAKSIGNGSPFPDLNIDRNDEIGQLAQSFVEMERNLRTDRLTNVLNRDSLIAQID 419 R LT A + +G G + + R DEIG+LA +F M +L TD LT NR +L + Sbjct: 378 RSLTRAVRRVGLGEIDTPIEVQRRDEIGELAHNFHRMRHSLFTDPLTGASNRSALQHILT 437 Query: 420 -FRRRNSSQAVPLHFALLFIDLDRFKAVNDEYGHDEGDKVLIAIAERLQHSLRHDDSVAR 478 R Q++ FALLF+DLDRFK +ND +GHD GD L I+ RL++ LR DD VAR Sbjct: 438 TLTRPLPGQSMAAPFALLFVDLDRFKPLNDRWGHDNGDLALAEISLRLRNLLRPDDVVAR 497 Query: 479 FGGDEFVVYLHGVTEMDVARSIADKIRHAVNKPIAG----RDGQDYTVDASVGVSLYPDD 534 GGDEF++ L GV++ + +++ KI HA+ +P+ +G+ TV ASVG +LYP D Sbjct: 498 LGGDEFILILRGVSDEEQVQAVRLKIEHALQQPLGTLQGIPEGEAVTVGASVGQALYPRD 557 Query: 535 GLDVETLLRVADSRMFDQKR 554 D ++LL+VAD M+ KR Sbjct: 558 AQDAQSLLKVADQDMYRNKR 577