BLASTP 2.2.17 [Aug-26-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= 0001.1383.p (426 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003775454.1| HlyD family secretion, possible efflux compo... 380 e-103 ref|YP_003976992.1| macrolide-specific efflux protein MacA [Achr... 292 6e-77 ref|ZP_08423233.1| efflux transporter, RND family, MFP subunit [... 290 3e-76 ref|ZP_06686003.1| macrolide efflux protein MacA [Achromobacter ... 282 7e-74 gb|EFV82898.1| ABC-type macrolide transporter [Achromobacter xyl... 279 7e-73 >ref|YP_003775454.1| HlyD family secretion, possible efflux component [Herbaspirillum seropedicae SmR1] gb|ADJ63546.1| HlyD family secretion, possible efflux component, protein [Herbaspirillum seropedicae SmR1] Length = 407 Score = 380 bits (976), Expect = e-103, Method: Composition-based stats. Identities = 224/267 (83%), Positives = 248/267 (92%), Gaps = 1/267 (0%) Query: 161 GGDASSRENFETAEATLNSTRADIAALQAQIKDGAIKVDTARLNLGYTRITAPIDGEVVA 220 GDASSRENFE+AEATLN+T+ADIAALQAQIKDGAIKVDTARLNLGYTRI++PI+G+VVA Sbjct: 141 AGDASSRENFESAEATLNTTQADIAALQAQIKDGAIKVDTARLNLGYTRISSPIEGQVVA 200 Query: 221 IVAQEGQTVNANQSTPTIIKVARMDTVTIKAQISEADVVRVKPGLPVYFTILGDPEHRYR 280 IVAQEGQTVNANQSTPTIIKVARMDTVTIKAQISEADVVRVKPG PV+FTILGDP+HRYR Sbjct: 201 IVAQEGQTVNANQSTPTIIKVARMDTVTIKAQISEADVVRVKPGQPVFFTILGDPDHRYR 260 Query: 281 TTLRAIEPAPDSILQDD-TTTSTTSTTTSSSSSTAIYYNGLLDLPNPDGKLRISMTTQVN 339 TTLRAIEPAPDSILQDD ++++T+ T++SS+SSTAIYYNGLLD+PNPDGKLRISMTTQVN Sbjct: 261 TTLRAIEPAPDSILQDDTSSSTTSITSSSSASSTAIYYNGLLDVPNPDGKLRISMTTQVN 320 Query: 340 IVLSEAKDALVVPSTALGAKDAQGRYTVRVLDAQGLAQERQVRTGINTNAQVQIIEGLKA 399 IVLSEA +ALV+PSTALGAK A G YTVRVLD QG A ER+VR GINTNA VQI+EG+KA Sbjct: 321 IVLSEASNALVLPSTALGAKAADGSYTVRVLDDQGQAHERKVRIGINTNALVQIVEGVKA 380 Query: 400 GERVVTGTAVPGTADSSSEHRGPPPRM 426 GERVVTGT +PG A SSS H GPPP M Sbjct: 381 GERVVTGTVLPGAAASSSAHDGPPPHM 407 >ref|YP_003976992.1| macrolide-specific efflux protein MacA [Achromobacter xylosoxidans A8] gb|ADP14277.1| macrolide-specific efflux protein MacA [Achromobacter xylosoxidans A8] Length = 394 Score = 292 bits (748), Expect = 6e-77, Method: Composition-based stats. Identities = 159/242 (65%), Positives = 193/242 (79%) Query: 161 GGDASSRENFETAEATLNSTRADIAALQAQIKDGAIKVDTARLNLGYTRITAPIDGEVVA 220 DASSRE++E+AEATL TRA+IA+L AQI I+VDTAR+NLGYTRI +PIDG VVA Sbjct: 139 AADASSRESYESAEATLGVTRAEIASLDAQIAQAEIQVDTARVNLGYTRIVSPIDGMVVA 198 Query: 221 IVAQEGQTVNANQSTPTIIKVARMDTVTIKAQISEADVVRVKPGLPVYFTILGDPEHRYR 280 +V +EGQTVN+ QS PTIIKVA++DT+TIKAQISEADV RVKPGLPVYFTILG+P+ RYR Sbjct: 199 VVTKEGQTVNSIQSAPTIIKVAQVDTMTIKAQISEADVTRVKPGLPVYFTILGEPDERYR 258 Query: 281 TTLRAIEPAPDSILQDDTTTSTTSTTTSSSSSTAIYYNGLLDLPNPDGKLRISMTTQVNI 340 LRA+EPAPDS+ +DD T S T + + SS++ A+YYNGL D+PNPD KLRISMT QV I Sbjct: 259 AQLRAVEPAPDSVQKDDATASLTGSASGSSTTAAVYYNGLFDVPNPDEKLRISMTAQVFI 318 Query: 341 VLSEAKDALVVPSTALGAKDAQGRYTVRVLDAQGLAQERQVRTGINTNAQVQIIEGLKAG 400 VL EAKD +VVPS+ALG + GRY VRV+ + RQVR G+N N Q Q++EGL+ G Sbjct: 319 VLGEAKDTVVVPSSALGKRGEDGRYAVRVVLKDNKTETRQVRIGMNNNVQAQVLEGLEVG 378 Query: 401 ER 402 ER Sbjct: 379 ER 380 >ref|ZP_08423233.1| efflux transporter, RND family, MFP subunit [Desulfovibrio africanus str. Walvis Bay] gb|EGJ50338.1| efflux transporter, RND family, MFP subunit [Desulfovibrio africanus str. Walvis Bay] Length = 390 Score = 290 bits (742), Expect = 3e-76, Method: Composition-based stats. Identities = 162/264 (61%), Positives = 212/264 (80%), Gaps = 3/264 (1%) Query: 163 DASSRENFETAEATLNSTRADIAALQAQIKDGAIKVDTARLNLGYTRITAPIDGEVVAIV 222 DA+SR+++E+A+ATLN+TRADIAAL AQI +I VDTAR++LGYTRIT+P+DG VVAIV Sbjct: 128 DATSRQDYESAQATLNATRADIAALDAQIVQASIAVDTARIDLGYTRITSPMDGVVVAIV 187 Query: 223 AQEGQTVNANQSTPTIIKVARMDTVTIKAQISEADVVRVKPGLPVYFTILGDPEHRYRTT 282 +EGQTVNA Q PTI+KVA++DT+T++A+ISEADVVRV+PG VYFTILG+P+HRY T Sbjct: 188 TKEGQTVNAAQEAPTIVKVAQLDTMTVEAEISEADVVRVEPGQRVYFTILGEPDHRYEAT 247 Query: 283 LRAIEPAPDSILQDDTTTSTTSTTTSSSSSTAIYYNGLLDLPNPDGKLRISMTTQVNIVL 342 LR+IEPAP+SI D+++++++S+++S AIYYNGL D+PNP KLRISMT QV IVL Sbjct: 248 LRSIEPAPESIAYDESSSTSSSSSSSDE---AIYYNGLFDVPNPGHKLRISMTAQVTIVL 304 Query: 343 SEAKDALVVPSTALGAKDAQGRYTVRVLDAQGLAQERQVRTGINTNAQVQIIEGLKAGER 402 +E KDAL +PS ALGAKDAQGRYTVRVL+ G+ ++R VR G+N QI+EGL+ G R Sbjct: 305 NETKDALTIPSGALGAKDAQGRYTVRVLNQDGMPEKRTVRVGMNDTVNAQILEGLERGGR 364 Query: 403 VVTGTAVPGTADSSSEHRGPPPRM 426 V+ G A +A+S ++ P P M Sbjct: 365 VIVGEAAADSAESEEDNARPRPPM 388 >ref|ZP_06686003.1| macrolide efflux protein MacA [Achromobacter piechaudii ATCC 43553] gb|EFF77078.1| macrolide efflux protein MacA [Achromobacter piechaudii ATCC 43553] Length = 395 Score = 282 bits (722), Expect = 7e-74, Method: Composition-based stats. Identities = 161/253 (63%), Positives = 202/253 (79%), Gaps = 1/253 (0%) Query: 161 GGDASSRENFETAEATLNSTRADIAALQAQIKDGAIKVDTARLNLGYTRITAPIDGEVVA 220 DASSRE +E+AEATL TRA+IA+L AQI I+VDTA++NLGYTRI +PIDG+VVA Sbjct: 139 AADASSREAYESAEATLGVTRAEIASLDAQIAQAEIQVDTAKVNLGYTRIVSPIDGKVVA 198 Query: 221 IVAQEGQTVNANQSTPTIIKVARMDTVTIKAQISEADVVRVKPGLPVYFTILGDPEHRYR 280 +V +EGQTVN+ QS PTIIKVA++DT+TIKAQISEADV RVKPGLPVYFTILG+P+ RY Sbjct: 199 VVTKEGQTVNSIQSAPTIIKVAQVDTMTIKAQISEADVTRVKPGLPVYFTILGEPDQRYE 258 Query: 281 TTLRAIEPAPDSILQDDTTTSTTSTTTSSSSSTAIYYNGLLDLPNPDGKLRISMTTQVNI 340 TLRA+EPAPDSI +DD T+S TS+T SS+++ A+YYNGL D+PNPD KLRISMT QV I Sbjct: 259 ATLRAVEPAPDSIQKDDATSSLTSSTGSSTTA-AVYYNGLFDVPNPDEKLRISMTAQVFI 317 Query: 341 VLSEAKDALVVPSTALGAKDAQGRYTVRVLDAQGLAQERQVRTGINTNAQVQIIEGLKAG 400 VL EA+DA+VVP++ALG + GRY VRV+ + R V+ G+N + Q Q++EGL+ G Sbjct: 318 VLGEARDAVVVPASALGKRGEDGRYAVRVVLKDNKTEVRHVKIGMNNSVQAQVLEGLEVG 377 Query: 401 ERVVTGTAVPGTA 413 ERVV+ + P A Sbjct: 378 ERVVSADSAPAVA 390 >gb|EFV82898.1| ABC-type macrolide transporter [Achromobacter xylosoxidans C54] Length = 394 Score = 279 bits (713), Expect = 7e-73, Method: Composition-based stats. Identities = 158/242 (65%), Positives = 195/242 (80%), Gaps = 1/242 (0%) Query: 161 GGDASSRENFETAEATLNSTRADIAALQAQIKDGAIKVDTARLNLGYTRITAPIDGEVVA 220 DASSRE FE+AEATL TRADIAAL AQI I+VD A++NLGYTRI +PIDG VVA Sbjct: 139 AADASSREAFESAEATLGVTRADIAALDAQIVQAEIEVDKAKVNLGYTRIVSPIDGVVVA 198 Query: 221 IVAQEGQTVNANQSTPTIIKVARMDTVTIKAQISEADVVRVKPGLPVYFTILGDPEHRYR 280 +V +EGQTVNA QS PTIIKVA++ T+TIKAQISEADV RVKPGLPVYFTILG+P+HRY Sbjct: 199 VVTKEGQTVNAIQSAPTIIKVAQVATMTIKAQISEADVTRVKPGLPVYFTILGEPDHRYH 258 Query: 281 TTLRAIEPAPDSILQDDTTTSTTSTTTSSSSSTAIYYNGLLDLPNPDGKLRISMTTQVNI 340 TLRA+EPAPDSI +DD T + ++++S+S+S A+YYNGL D+PNPD KLRISMT QV+I Sbjct: 259 ATLRAVEPAPDSIQKDDAAT-SLTSSSSTSTSAAVYYNGLFDVPNPDEKLRISMTAQVSI 317 Query: 341 VLSEAKDALVVPSTALGAKDAQGRYTVRVLDAQGLAQERQVRTGINTNAQVQIIEGLKAG 400 VL EA+DA+VVP++ALG + GRY VRV+ + R+V+ G+N N Q Q++EGL+ G Sbjct: 318 VLGEARDAVVVPASALGKRGEDGRYEVRVVGKDNQTETRKVKIGMNNNVQAQVLEGLEVG 377 Query: 401 ER 402 ER Sbjct: 378 ER 379