BLASTP 2.2.17 [Aug-26-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= 0001.1199.p (418 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003774820.1| isocitrate dehydrogenase [Herbaspirillum ser... 765 0.0 ref|YP_004753915.1| isocitrate dehydrogenase [NADP] [Collimonas ... 708 0.0 ref|YP_002006523.1| isocitrate dehydrogenase [Cupriavidus taiwan... 701 0.0 ref|YP_585037.1| isocitrate dehydrogenase [Cupriavidus metallidu... 700 0.0 ref|YP_296961.1| isocitrate dehydrogenase [Ralstonia eutropha JM... 699 0.0 >ref|YP_003774820.1| isocitrate dehydrogenase [Herbaspirillum seropedicae SmR1] gb|ADJ62912.1| isocitrate dehydrogenase (NADP) protein [Herbaspirillum seropedicae SmR1] Length = 418 Score = 765 bits (1976), Expect = 0.0, Method: Composition-based stats. Identities = 369/418 (88%), Positives = 397/418 (94%) Query: 1 MSYQHIQVPAEGRKITANADDTLNVPNNPIIPFIMGDGVGVDVTPVMLKVVDAAVEKAYG 60 MSYQHIQVPAEGRKITANADDTLNVPNNPIIP+I+GDGVGVDVTPVMLKVV+AAVEKAYG Sbjct: 1 MSYQHIQVPAEGRKITANADDTLNVPNNPIIPYIVGDGVGVDVTPVMLKVVNAAVEKAYG 60 Query: 61 GARKIHWMEIYAGEKSTKLYGADTWLPEETLDVLKEYLVSIKGPLSTPVGGGIRSLNVTM 120 GARKIHWMEIYAGEK+T+LYG D WLPEETL VLK+YLV+IKGPLSTPVGGGIRSLNV M Sbjct: 61 GARKIHWMEIYAGEKATRLYGPDVWLPEETLAVLKKYLVAIKGPLSTPVGGGIRSLNVAM 120 Query: 121 RQQLDLYVCLRPVRYFKGVPSPLKEPEKTDMVIFRENSEDIYAGIEWQAGTPEVKKLIEL 180 RQQLDLYVCLRPVRYFKGVPSPL+EPEKTDMVIFRENSEDIYAGIEW AGTPEV KLI+L Sbjct: 121 RQQLDLYVCLRPVRYFKGVPSPLREPEKTDMVIFRENSEDIYAGIEWAAGTPEVNKLIDL 180 Query: 181 LTREMGVKKLRFPETSALGIKPVSREGTERLVRKAIQYAIDHDKPSVTLVHKGNIMKYTE 240 LTREMGVKKLRFPE+SALGIKPVSREGTERLVR+AIQYAIDHDKPSVTLVHKGNIMK+TE Sbjct: 181 LTREMGVKKLRFPESSALGIKPVSREGTERLVRQAIQYAIDHDKPSVTLVHKGNIMKFTE 240 Query: 241 GIFRDWAYALPQKEFGGVVIDDGPWVRIKNPKTGRDIIVKDVIADAFMQQILLRPAEYSV 300 G FRDW YAL +EFG +IDDGPW+R+KNPKTGR II+KD I DAF QQ+L+RPAEYSV Sbjct: 241 GAFRDWGYALAAREFGAELIDDGPWMRLKNPKTGRAIIIKDAITDAFFQQVLMRPAEYSV 300 Query: 301 IATMNLNGDYISDAVAAQVGGIGIAPGANMSDSVAVFEATHGTAPKYAGKDYVNPGSLIL 360 IAT+NLNGDYISDAVAAQVGGIGIAPGANMSDSVAVFEATHGTAPKYAGKDYVNPGS IL Sbjct: 301 IATLNLNGDYISDAVAAQVGGIGIAPGANMSDSVAVFEATHGTAPKYAGKDYVNPGSSIL 360 Query: 361 SAEMMLRHIGWTEAAALIIEAMQKTISSKKVTYDFARLMEGATQVSCSGFGDAVIENL 418 SAEMMLRH+GW EAA LII AMQK++SSK+VTYDFARL+EGATQVSCSGFG+ +IEN+ Sbjct: 361 SAEMMLRHMGWIEAADLIISAMQKSVSSKRVTYDFARLLEGATQVSCSGFGEVMIENM 418 >ref|YP_004753915.1| isocitrate dehydrogenase [NADP] [Collimonas fungivorans Ter331] gb|AEK63092.1| Isocitrate dehydrogenase [NADP] [Collimonas fungivorans Ter331] Length = 417 Score = 708 bits (1828), Expect = 0.0, Method: Composition-based stats. Identities = 339/415 (81%), Positives = 383/415 (92%) Query: 4 QHIQVPAEGRKITANADDTLNVPNNPIIPFIMGDGVGVDVTPVMLKVVDAAVEKAYGGAR 63 QHI+VPAEG+KIT NAD ++NVP+NPIIP+I GDG GVD++PVM+KVVDAAV KAY G R Sbjct: 3 QHIKVPAEGKKITVNADFSINVPDNPIIPYIEGDGTGVDISPVMIKVVDAAVSKAYAGKR 62 Query: 64 KIHWMEIYAGEKSTKLYGADTWLPEETLDVLKEYLVSIKGPLSTPVGGGIRSLNVTMRQQ 123 KI WME++AGEKSTK+YG D WLPEETL +K+Y+VSIKGPL+TPVGGGIRSLNV +RQ+ Sbjct: 63 KISWMEVFAGEKSTKVYGPDVWLPEETLAAIKDYVVSIKGPLTTPVGGGIRSLNVALRQE 122 Query: 124 LDLYVCLRPVRYFKGVPSPLKEPEKTDMVIFRENSEDIYAGIEWQAGTPEVKKLIELLTR 183 LDLYVCLRPVRYFKGVPSP++EPEKTDMVIFRENSEDIYAGIEWQ G+ KKLIE L + Sbjct: 123 LDLYVCLRPVRYFKGVPSPVREPEKTDMVIFRENSEDIYAGIEWQEGSDGAKKLIEFLIK 182 Query: 184 EMGVKKLRFPETSALGIKPVSREGTERLVRKAIQYAIDHDKPSVTLVHKGNIMKYTEGIF 243 EMGVKK+RFP+TS +G+KPVSREGTERLVRKAIQYAID+DKPSVT+VHKGNIMK+TEG F Sbjct: 183 EMGVKKIRFPDTSGIGVKPVSREGTERLVRKAIQYAIDNDKPSVTIVHKGNIMKFTEGGF 242 Query: 244 RDWAYALPQKEFGGVVIDDGPWVRIKNPKTGRDIIVKDVIADAFMQQILLRPAEYSVIAT 303 RDWAYAL QKEFG +ID GPW + KNPKTGR+IIVKD IADAF+QQILLRP EYSVIAT Sbjct: 243 RDWAYALAQKEFGAELIDGGPWAKFKNPKTGREIIVKDSIADAFLQQILLRPNEYSVIAT 302 Query: 304 MNLNGDYISDAVAAQVGGIGIAPGANMSDSVAVFEATHGTAPKYAGKDYVNPGSLILSAE 363 +NLNGDYISDA+AAQVGGIGIAPGAN+SDSVA+FEATHGTAPKYAGKDYVNPGSLILSAE Sbjct: 303 LNLNGDYISDALAAQVGGIGIAPGANLSDSVAMFEATHGTAPKYAGKDYVNPGSLILSAE 362 Query: 364 MMLRHIGWTEAAALIIEAMQKTISSKKVTYDFARLMEGATQVSCSGFGDAVIENL 418 MMLRH+GW EAA LIIE+MQK+I+SKKVTYDFARLMEGATQVSCSGFG+ +IEN+ Sbjct: 363 MMLRHMGWVEAADLIIESMQKSITSKKVTYDFARLMEGATQVSCSGFGEVLIENM 417 >ref|YP_002006523.1| isocitrate dehydrogenase [Cupriavidus taiwanensis LMG 19424] emb|CAQ70462.1| Isocitrate (NADP) dehydrogenase [Cupriavidus taiwanensis LMG 19424] Length = 416 Score = 701 bits (1810), Expect = 0.0, Method: Composition-based stats. Identities = 339/416 (81%), Positives = 377/416 (90%), Gaps = 1/416 (0%) Query: 3 YQHIQVPAEGRKITANADDTLNVPNNPIIPFIMGDGVGVDVTPVMLKVVDAAVEKAYGGA 62 YQHI+VPA G KIT N D +LNVP+NPIIP+I GDG G+D+TPVM+KVVDAAV KAYGG Sbjct: 2 YQHIKVPA-GEKITVNQDFSLNVPDNPIIPYIEGDGTGLDITPVMIKVVDAAVAKAYGGK 60 Query: 63 RKIHWMEIYAGEKSTKLYGADTWLPEETLDVLKEYLVSIKGPLSTPVGGGIRSLNVTMRQ 122 RKI WMEIYAGEKSTK+YG D WLP+ETLDVLKEY+VSIKGPL+TPVGGGIRSLNV +RQ Sbjct: 61 RKIAWMEIYAGEKSTKVYGPDVWLPDETLDVLKEYVVSIKGPLTTPVGGGIRSLNVALRQ 120 Query: 123 QLDLYVCLRPVRYFKGVPSPLKEPEKTDMVIFRENSEDIYAGIEWQAGTPEVKKLIELLT 182 QLDLYVCLRPVRYFKGVPSP++EPEKTDMVIFRENSEDIYAGIEW A + + KKLI L Sbjct: 121 QLDLYVCLRPVRYFKGVPSPVREPEKTDMVIFRENSEDIYAGIEWAAESDQAKKLIAFLQ 180 Query: 183 REMGVKKLRFPETSALGIKPVSREGTERLVRKAIQYAIDHDKPSVTLVHKGNIMKYTEGI 242 EMGVKK+RFP TS +G+KPVSREGTERLVRKAIQYAID+DKPSVTLVHKGNIMK+TEG Sbjct: 181 NEMGVKKIRFPATSGIGVKPVSREGTERLVRKAIQYAIDNDKPSVTLVHKGNIMKFTEGG 240 Query: 243 FRDWAYALPQKEFGGVVIDDGPWVRIKNPKTGRDIIVKDVIADAFMQQILLRPAEYSVIA 302 FRDW Y L QKEFG ++D GPW + KNPKTG+DI+VKD IADAF+QQILLRPAEYSVIA Sbjct: 241 FRDWGYELAQKEFGAELVDGGPWCKFKNPKTGKDIVVKDAIADAFLQQILLRPAEYSVIA 300 Query: 303 TMNLNGDYISDAVAAQVGGIGIAPGANMSDSVAVFEATHGTAPKYAGKDYVNPGSLILSA 362 T+NLNGDYISDA+AAQVGGIGIAPGANMSDSVA+FEATHGTAPKYAGKDYVNPGS ILSA Sbjct: 301 TLNLNGDYISDALAAQVGGIGIAPGANMSDSVAMFEATHGTAPKYAGKDYVNPGSEILSA 360 Query: 363 EMMLRHIGWTEAAALIIEAMQKTISSKKVTYDFARLMEGATQVSCSGFGDAVIENL 418 EMMLRH+GWTEAA LII +M+K+I SKKVTYDFARL+EGATQVSCSGFG +I+N+ Sbjct: 361 EMMLRHMGWTEAADLIIASMEKSILSKKVTYDFARLLEGATQVSCSGFGQVMIDNM 416 >ref|YP_585037.1| isocitrate dehydrogenase [Cupriavidus metallidurans CH34] gb|ABF09768.1| isocitrate dehydrogenase, specific for NADP+ [Cupriavidus metallidurans CH34] Length = 416 Score = 700 bits (1807), Expect = 0.0, Method: Composition-based stats. Identities = 338/416 (81%), Positives = 378/416 (90%), Gaps = 1/416 (0%) Query: 3 YQHIQVPAEGRKITANADDTLNVPNNPIIPFIMGDGVGVDVTPVMLKVVDAAVEKAYGGA 62 YQHI+VPA G KI NAD +LNVP+NPIIP+I GDG GVD+TPVMLKVVDAAV KAYGG Sbjct: 2 YQHIKVPA-GEKIKVNADLSLNVPDNPIIPYIEGDGTGVDITPVMLKVVDAAVAKAYGGK 60 Query: 63 RKIHWMEIYAGEKSTKLYGADTWLPEETLDVLKEYLVSIKGPLSTPVGGGIRSLNVTMRQ 122 RKI WMEIYAGEKSTK+YG D WLPEET++V+KEY+VSIKGPL+TPVGGGIRSLNV +RQ Sbjct: 61 RKISWMEIYAGEKSTKVYGPDVWLPEETMEVVKEYVVSIKGPLTTPVGGGIRSLNVALRQ 120 Query: 123 QLDLYVCLRPVRYFKGVPSPLKEPEKTDMVIFRENSEDIYAGIEWQAGTPEVKKLIELLT 182 QLDLYVCLRPVRYFKGVPSP++EPEKTDMVIFRENSEDIYAGIEW+A + KKLI L Sbjct: 121 QLDLYVCLRPVRYFKGVPSPVREPEKTDMVIFRENSEDIYAGIEWEAESEGAKKLIAFLQ 180 Query: 183 REMGVKKLRFPETSALGIKPVSREGTERLVRKAIQYAIDHDKPSVTLVHKGNIMKYTEGI 242 EMGVKK+RFPETS +GIKPVS+EGT+RLVRKA+QYAID+DKPSVTLVHKGNIMK+TEG Sbjct: 181 NEMGVKKIRFPETSGIGIKPVSKEGTQRLVRKALQYAIDNDKPSVTLVHKGNIMKFTEGG 240 Query: 243 FRDWAYALPQKEFGGVVIDDGPWVRIKNPKTGRDIIVKDVIADAFMQQILLRPAEYSVIA 302 FRDW Y L Q+EFG ++D GPW + KNPKTGRDI+VKD IADAF+QQILLRPAEYSVIA Sbjct: 241 FRDWGYELAQQEFGAELVDGGPWCKFKNPKTGRDIVVKDAIADAFLQQILLRPAEYSVIA 300 Query: 303 TMNLNGDYISDAVAAQVGGIGIAPGANMSDSVAVFEATHGTAPKYAGKDYVNPGSLILSA 362 T+NLNGDYISDA+AAQVGGIGIAPGANMSDSVA+FEATHGTAPKYAGKDYVNPGS ILSA Sbjct: 301 TLNLNGDYISDALAAQVGGIGIAPGANMSDSVAMFEATHGTAPKYAGKDYVNPGSEILSA 360 Query: 363 EMMLRHIGWTEAAALIIEAMQKTISSKKVTYDFARLMEGATQVSCSGFGDAVIENL 418 EMMLRH+GWTEAA LII +M+K+I SKKVTYDFARL+EGATQVSCSGFG +I+N+ Sbjct: 361 EMMLRHMGWTEAADLIIRSMEKSIQSKKVTYDFARLLEGATQVSCSGFGQVMIDNM 416 >ref|YP_296961.1| isocitrate dehydrogenase [Ralstonia eutropha JMP134] gb|AAZ62117.1| isocitrate dehydrogenase (NADP) [Ralstonia eutropha JMP134] Length = 416 Score = 699 bits (1804), Expect = 0.0, Method: Composition-based stats. Identities = 335/416 (80%), Positives = 378/416 (90%), Gaps = 1/416 (0%) Query: 3 YQHIQVPAEGRKITANADDTLNVPNNPIIPFIMGDGVGVDVTPVMLKVVDAAVEKAYGGA 62 YQHI+VPA G KIT N D +LNVP+ PIIP+I GDG G+D+TPVM+KVVDAAVEKAY G Sbjct: 2 YQHIKVPA-GEKITVNQDFSLNVPDTPIIPYIEGDGTGLDITPVMIKVVDAAVEKAYAGK 60 Query: 63 RKIHWMEIYAGEKSTKLYGADTWLPEETLDVLKEYLVSIKGPLSTPVGGGIRSLNVTMRQ 122 RKI WMEIYAGEKSTK+YG D WLP+ETLDVLKEY+VSIKGPL+TPVGGGIRSLNV +RQ Sbjct: 61 RKISWMEIYAGEKSTKVYGPDVWLPDETLDVLKEYVVSIKGPLTTPVGGGIRSLNVALRQ 120 Query: 123 QLDLYVCLRPVRYFKGVPSPLKEPEKTDMVIFRENSEDIYAGIEWQAGTPEVKKLIELLT 182 QLDLYVCLRPVRYFKGVPSP++EPEKTDMVIFRENSEDIYAGIEW+A +P+ +KLI L Sbjct: 121 QLDLYVCLRPVRYFKGVPSPVREPEKTDMVIFRENSEDIYAGIEWEAESPQAQKLIAFLQ 180 Query: 183 REMGVKKLRFPETSALGIKPVSREGTERLVRKAIQYAIDHDKPSVTLVHKGNIMKYTEGI 242 EMGVKK+RFPETS +G+KPVS++GT+RLVRKAIQYAID+DKPSVTLVHKGNIMK+TEG Sbjct: 181 NEMGVKKIRFPETSGIGVKPVSKQGTQRLVRKAIQYAIDNDKPSVTLVHKGNIMKFTEGG 240 Query: 243 FRDWAYALPQKEFGGVVIDDGPWVRIKNPKTGRDIIVKDVIADAFMQQILLRPAEYSVIA 302 FRDW Y L QKEFG ++D GPW + KN KTGRDI++KD IADAF+QQILLRPAEYSVIA Sbjct: 241 FRDWGYELAQKEFGAELVDGGPWCKFKNSKTGRDIVIKDAIADAFLQQILLRPAEYSVIA 300 Query: 303 TMNLNGDYISDAVAAQVGGIGIAPGANMSDSVAVFEATHGTAPKYAGKDYVNPGSLILSA 362 T+NLNGDYISDA+AAQVGGIGIAPGAN+SDSVA+FEATHGTAPKYAGKDYVNPGS ILSA Sbjct: 301 TLNLNGDYISDALAAQVGGIGIAPGANLSDSVAMFEATHGTAPKYAGKDYVNPGSEILSA 360 Query: 363 EMMLRHIGWTEAAALIIEAMQKTISSKKVTYDFARLMEGATQVSCSGFGDAVIENL 418 EMMLRH+GWTEAA LII +M+K+I SKKVTYDFARL+EGATQVSCSGFG +IEN+ Sbjct: 361 EMMLRHMGWTEAADLIIASMEKSILSKKVTYDFARLLEGATQVSCSGFGQVMIENM 416