BLASTP 2.2.17 [Aug-26-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= 0001.0964.p (605 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003774654.1| composite two-component transcription regula... 755 0.0 ref|YP_982911.1| integral membrane sensor hybrid histidine kinas... 515 e-143 ref|YP_586986.1| two-component hybrid histidine kinase, periplas... 422 e-115 ref|YP_002007709.1| hybrid sensor histidine kinase [Cupriavidus ... 403 e-110 ref|YP_004681300.1| RpfC family transcriptional regulator [Cupri... 399 e-109 >ref|YP_003774654.1| composite two-component transcription regulator protein [Herbaspirillum seropedicae SmR1] gb|ADJ62746.1| composite two-component regulatory (sensor kinase and response regulator hybrid) transcription regulator protein [Herbaspirillum seropedicae SmR1] Length = 604 Score = 755 bits (1949), Expect = 0.0, Method: Composition-based stats. Identities = 441/612 (72%), Positives = 494/612 (80%), Gaps = 19/612 (3%) Query: 4 DGALGSAPVHAAGDDTLHRVRVEQVRLLCGNLGSSVLPGILVALLVAYALRESAGLWPLL 63 D + P A D H+++VEQ+RLLCGNLGSSV+PGILVALL+ YAL E AGLWPLL Sbjct: 2 DASSPPRPGTLAPDAVAHQIQVEQIRLLCGNLGSSVVPGILVALLIVYALGERAGLWPLL 61 Query: 64 AWAAGVIASKLFDYADARRMLRMEITPANIDQIKRRLVVLHGIDGAAWGLLAPLALDTAS 123 AWA GVI SKL D+ADARR+L M ITP I ++RRL++LHG+DGAAWG LA +ALDT S Sbjct: 62 AWAGGVIVSKLIDFADARRILAMSITPQQIGAVRRRLMLLHGLDGAAWGALAAVALDTGS 121 Query: 124 PGGSILLIGVLAGVAGNSMSILSPVLPAFVSFCLVELGMLAASAWHTHEDALEVLAVAAL 183 PGGSIL IGVLAGVAGNSMSILSPVLP F+SFC+VELGMLA W H+ +L+VL+ AAL Sbjct: 122 PGGSILAIGVLAGVAGNSMSILSPVLPVFISFCIVELGMLAGWVWIMHDPSLQVLSAAAL 181 Query: 184 LYVASLMVQARNSAGAARAAIMLRFENNALIERLQRESEKTQQALQQAEQANAAKSRFLA 243 LYVASL+VQARNSA AA+AAI LR+EN LI RLQ ESE+TQQAL QAEQANAAKS+FLA Sbjct: 182 LYVASLLVQARNSARAAQAAITLRYENTELIRRLQHESERTQQALAQAEQANAAKSKFLA 241 Query: 244 GASHDLRQPIHAQGLFLEVLSNTPLDPMQREVVGRLRNAADNCADMLHTLLDYSRIEAGV 303 ASHDLRQPIHAQGLFLEVL+ TPLDPMQR+VV +LR AADNCADMLHTLLDYSRIEAGV Sbjct: 242 AASHDLRQPIHAQGLFLEVLNTTPLDPMQRDVVAKLRRAADNCADMLHTLLDYSRIEAGV 301 Query: 304 VTPQLAPFRPQALIHRISREMAAQAEARGLVFRTRESQAVASADAGLTELILRNLVSNAI 363 V PQ+ FR QAL+ RIS+EMAAQAEA+GLVFR RES+AV SADA LTELILRNLVSNAI Sbjct: 302 VEPQVTRFRVQALVGRISQEMAAQAEAKGLVFRCRESRAVVSADASLTELILRNLVSNAI 361 Query: 364 RYTERGGVLVACRQRGPQVWLEVWDTGIGIAPEQQQEIFREFHQLGNPERDHNKGMGLGL 423 RYT+RGG+LVACRQRG Q WLEVWDTG GI+ QQQEIF EF QLGNPERDH KG+GLGL Sbjct: 362 RYTDRGGILVACRQRGGQAWLEVWDTGAGISAAQQQEIFEEFRQLGNPERDHRKGLGLGL 421 Query: 424 AIAEGLAKMQGLQLTVQSRPGRGSVFRLQLP----------AALMPLPAHPGKPAPALTA 473 AIA+GLA++QGL L+VQS PGRGSVFRL LP AAL PLP Sbjct: 422 AIAQGLARLQGLTLSVQSVPGRGSVFRLTLPLARQDDASLAAALRPLPP---------PV 472 Query: 474 QRDLHGLRILLIDDDQRVRDSMAQLLGQWGCHCIDVEGLEEAEALAHSQEFDVVISDYRL 533 + DLHGLR+LLIDDDQRVR+SMAQLL WGC C E LE+AEALA ++VISDYRL Sbjct: 473 RHDLHGLRVLLIDDDQRVRESMAQLLEHWGCRCHCAESLEQAEALAQQHLPELVISDYRL 532 Query: 534 RAHRNGTEAIAAVRAASQAHVGALLITGDTAPARLREASESGIPMLHKPVAPAQLWEALL 593 R H NGT+AIA VR V ALLITGDTAPARLREA+ESGIPMLHKPVAPAQLWE L Sbjct: 533 RQHSNGTDAIAVVRRVLGKPVSALLITGDTAPARLREAAESGIPMLHKPVAPAQLWEQLQ 592 Query: 594 RLAAKAGGVHPQ 605 RL+ +A HP+ Sbjct: 593 RLSGQARQAHPR 604 >ref|YP_982911.1| integral membrane sensor hybrid histidine kinase [Polaromonas naphthalenivorans CJ2] gb|ABM37990.1| integral membrane sensor hybrid histidine kinase [Polaromonas naphthalenivorans CJ2] Length = 589 Score = 515 bits (1326), Expect = e-143, Method: Composition-based stats. Identities = 303/579 (52%), Positives = 394/579 (68%), Gaps = 7/579 (1%) Query: 19 TLHRVRVEQVRLLCGNLGSSVLPGILVALLVAYALRESAGLWPLLAWAAGVIASKLFDYA 78 T V VEQVRLLC N+GSSV+P ++ L+ + L + L W A SKL + Sbjct: 9 TESHVLVEQVRLLCANVGSSVIPTFVLLGLLFWVLSGDVNVMWLGLWCALTALSKLCCWL 68 Query: 79 DARRMLRMEITPANIDQIKRRLVVLHGIDGAAWGLLAPLALDTASPGGSILLIGVLAGVA 138 A+R L ++ ++ ++ L+VL+ +DGA WG L +ALD+A GS+L+I VL GVA Sbjct: 69 HAKRQLSRGVSVDSVPRLVWMLIVLNALDGAIWGALPWVALDSAHLAGSVLVIAVLTGVA 128 Query: 139 GNSMSILSPVLPAFVSFCLVELGMLAASAWHTHEDALEVLAVAALLYVASLMVQARNSAG 198 NSMS+LSPVLP FV F + E+ + + + A L +A LY A +M QA N A Sbjct: 129 ANSMSLLSPVLPVFVGFVIAEMIAGVSKLFLIGDPAYSALGIAGFLYFAIMMGQAINIAR 188 Query: 199 AARAAIMLRFENNALIERLQRESEKTQQALQQAEQANAAKSRFLAGASHDLRQPIHAQGL 258 AR +I LRFEN L+++L++++ + A +AE+ANAAKS+FLA ASHDLRQPIHAQGL Sbjct: 189 TARTSIDLRFENIELMDQLRKKTAIAEAARHEAEEANAAKSKFLAAASHDLRQPIHAQGL 248 Query: 259 FLEVLSNTPLDPMQREVVGRLRNAADNCADMLHTLLDYSRIEAGVVTPQLAPFRPQALIH 318 FLEVL + L QREV+ R+A+ ++ML+TLLD+SRI+AGVV P + PF+ Q L+H Sbjct: 249 FLEVLGQSLLTAHQREVLDCARSASLASSEMLNTLLDFSRIDAGVVRPHIQPFQLQTLLH 308 Query: 319 RISREMAAQAEARGLVFRTRESQAVASADAGLTELILRNLVSNAIRYTERGGVLVACRQR 378 +I ++A A+A+G+V+R+RE++A ++DA L E+ILRNLVSNAIRYTERGGVL+ CR+R Sbjct: 309 KIENDLAPLADAKGMVYRSRETRATINSDATLVEMILRNLVSNAIRYTERGGVLITCRKR 368 Query: 379 GPQVWLEVWDTGIGIAPEQQQEIFREFHQLGNPERDHNKGMGLGLAIAEGLAKMQGLQLT 438 +EVWDTGIGIA E QQ+IFREFHQLGNPERD KG+GLGLAIA+GLAK G L+ Sbjct: 369 RHLALVEVWDTGIGIAFENQQDIFREFHQLGNPERDRRKGLGLGLAIADGLAKALGRDLS 428 Query: 439 VQSRPGRGSVFRLQLPAALMPL-PAHP-GKPAPALTAQRDLHGLRILLIDDDQRVRDSMA 496 + SRPGRGSVFRL LP + + P P KP PA L G+ +L++DDD+ V MA Sbjct: 429 LSSRPGRGSVFRLALPLSHATVAPVEPVWKPDPA-----HLQGMHVLVVDDDEAVVLGMA 483 Query: 497 QLLGQWGCHCIDVEGLEEAEALAHSQEFDVVISDYRLRAHRNGTEAIAAVRAASQAHVGA 556 QLL WGC C + +A ALA +VVISDYRLR R G EAIAA+R + A Sbjct: 484 QLLQGWGCRCDTAGSIADALALARMHTPNVVISDYRLREQRTGAEAIAALRGMLGKQIPA 543 Query: 557 LLITGDTAPARLREASESGIPMLHKPVAPAQLWEALLRL 595 L+ITGDTAP RLREA S +P+LHKPVAP QL+ AL L Sbjct: 544 LMITGDTAPERLREAMASDVPLLHKPVAPDQLYRALGEL 582 >ref|YP_586986.1| two-component hybrid histidine kinase, periplasmic sensor [Cupriavidus metallidurans CH34] gb|ABF11717.1| putative two-component hybrid histidine kinase, periplasmic sensor [Cupriavidus metallidurans CH34] Length = 591 Score = 422 bits (1084), Expect = e-115, Method: Composition-based stats. Identities = 249/571 (43%), Positives = 351/571 (61%), Gaps = 6/571 (1%) Query: 22 RVRVEQVRLLCGNLGSSVLPGILVALLVAYALRESAGLWPLLAWAAGVIASKLFDYADAR 81 R+ Q+ L+ + G ++L L A+++A L + G + WAA ++ + R Sbjct: 13 RLLAAQMELIDQSFGIAMLGCSLAAIILAVGLTVTGGHPGAMPWAAAMVVLCAIAHF-GR 71 Query: 82 RMLRMEITPANIDQIKRRLVVLHGIDGAAWGLLAPLALDTASPGGSILLIGVLAGVAGNS 141 + +T A + R + V+ + G+ WGL+A L LD SP I ++ ++AG++ + Sbjct: 72 LAVPDRLTEARAGRYARAMTVMLVLIGSLWGLVAWLYLDIRSPAVVICVLSLIAGMSAAA 131 Query: 142 MSILSPVLPAFVSFCLVELGMLAASAWHTHEDALEVLAVAALLYVASLMVQARNSAGAAR 201 ++I S LP + F + + + TH+ A + LY+ L++ ARN + A Sbjct: 132 LAIFSACLPVAIGFFIPAILPVWIVFLLTHDIAYLPMFFGTPLYLVVLLIFARNYSRVAC 191 Query: 202 AAIMLRFENNALIERLQRESEKTQQALQQAEQANAAKSRFLAGASHDLRQPIHAQGLFLE 261 +I LRFEN LI +L+ ++ + QAL++AE AN AKS FLA ASHDLRQP+HA GLFL Sbjct: 192 HSIALRFENVELISQLRDQTARAGQALREAENANRAKSVFLASASHDLRQPLHALGLFLV 251 Query: 262 VLSNTPLDPMQREVVGRLRNAADNCADMLHTLLDYSRIEAGVVTPQLAPFRPQALIHRIS 321 L TPLD QR+++ + ++ +ML+TLLD+S++EAGV+T + PFR Q ++H++ Sbjct: 252 SLGRTPLDAHQRQLLDHIEASSGAAREMLNTLLDFSKLEAGVITARPRPFRLQPMLHKLE 311 Query: 322 REMAAQAEARGLVFRTRESQAVASADAGLTELILRNLVSNAIRYTERGGVLVACRQRGPQ 381 E A QA ARGLV+RTR++ A D L ELILRNL++NAIRYT GGVL+ACR R Sbjct: 312 NEFAPQANARGLVYRTRDTTATLFGDPALVELILRNLIANAIRYTHTGGVLIACRPRRFH 371 Query: 382 VWLEVWDTGIGIAPEQQQEIFREFHQLGNPERDHNKGMGLGLAIAEGLAKMQGLQLTVQS 441 +EVWDTGIGI Q +EIFREFHQLGNPERD KG+GLGLAI +GLA+ ++T+ S Sbjct: 372 ASIEVWDTGIGIPIAQHREIFREFHQLGNPERDQRKGLGLGLAIVDGLARTMQTRVTLDS 431 Query: 442 RPGRGSVFRLQLPAALMPLPAHPGKPAPALTAQRDLHGLRILLIDDDQRVRDSMAQLLGQ 501 P RGSVFRLQLP A P P + L GLR+L+IDDD +R +MA+LL Sbjct: 432 IPERGSVFRLQLPLAWAA-PEEVTFPGSVIR----LDGLRVLVIDDDPAIRQAMAELLAA 486 Query: 502 WGCHCIDVEGLEEAEALAHSQEFDVVISDYRLRAHRNGTEAIAAVRAASQAHVGALLITG 561 W C C E +EA L + D++++DYRLR HRNG EAIAA+R + + A++ITG Sbjct: 487 WDCDCRPAESEDEALGLLGTFTPDLILADYRLRGHRNGHEAIAAIRERTSQALPAIIITG 546 Query: 562 DTAPARLREASESGIPMLHKPVAPAQLWEAL 592 DTA +LR G +LHKPV P +L A+ Sbjct: 547 DTAADQLRNVHAGGTALLHKPVVPGELHSAI 577 >ref|YP_002007709.1| hybrid sensor histidine kinase [Cupriavidus taiwanensis LMG 19424] emb|CAQ71652.1| putative hybrid sensor histidine kinase [Cupriavidus taiwanensis LMG 19424] Length = 613 Score = 403 bits (1035), Expect = e-110, Method: Composition-based stats. Identities = 245/571 (42%), Positives = 350/571 (61%), Gaps = 6/571 (1%) Query: 22 RVRVEQVRLLCGNLGSSVLPGILVALLVAYALRESAGLWPLLAWAAGVIASKLFDYADAR 81 R+ Q+ L+ + G ++ L A+++A L + L WA ++ Y R Sbjct: 27 RLLAAQMNLIDQSFGCAMAGCSLAAIILAVGLTLNGHRPGALPWAVAMVLVCAVAYF-GR 85 Query: 82 RMLRMEITPANIDQIKRRLVVLHGIDGAAWGLLAPLALDTASPGGSILLIGVLAGVAGNS 141 L +T A + + + + GA WGL+A L LD P I ++ ++AG++ + Sbjct: 86 LRLPGRLTEAGATRYAHGMTAMLVLIGALWGLVAWLYLDVRLPAVVICILSLIAGMSAAA 145 Query: 142 MSILSPVLPAFVSFCLVELGMLAASAWHTHEDALEVLAVAALLYVASLMVQARNSAGAAR 201 +++ S LP + F + + + + T + + + LY+ L+V ARN A AR Sbjct: 146 LAVFSACLPVAIGFFVPAIVPVWIAFLATGDIEYLPMFLGTPLYLCVLLVFARNYAHVAR 205 Query: 202 AAIMLRFENNALIERLQRESEKTQQALQQAEQANAAKSRFLAGASHDLRQPIHAQGLFLE 261 +I LRFEN LI +L+ ++ + + A AE+A+ AKS FLA ASHDLRQP+HA GLFL Sbjct: 206 QSIALRFENVELISQLREQTARAEAAQHAAEEASRAKSVFLASASHDLRQPLHAMGLFLV 265 Query: 262 VLSNTPLDPMQREVVGRLRNAADNCADMLHTLLDYSRIEAGVVTPQLAPFRPQALIHRIS 321 L T LD QR+++ + ++ +ML++LLD+S++EAGV+TP+ FR Q L+H++ Sbjct: 266 SLGRTCLDERQRQLLAHIEASSGAAREMLNSLLDFSKLEAGVITPRARAFRLQPLLHKLE 325 Query: 322 REMAAQAEARGLVFRTRESQAVASADAGLTELILRNLVSNAIRYTERGGVLVACRQRGPQ 381 E A QAEARGLV+RTR++ D L EL+LRNL+SNAIRYT++GGVLVACR+RG + Sbjct: 326 NEFAPQAEARGLVYRTRDTTVTLHGDPTLVELVLRNLISNAIRYTQQGGVLVACRKRGVR 385 Query: 382 VWLEVWDTGIGIAPEQQQEIFREFHQLGNPERDHNKGMGLGLAIAEGLAKMQGLQLTVQS 441 +EVWDTGIGI Q ++IFREFHQL NPERD KG+GLGLAI +GLA+ ++T+ S Sbjct: 386 ATIEVWDTGIGIPSAQHRDIFREFHQLDNPERDQRKGLGLGLAIVDGLARTMRTRVTLAS 445 Query: 442 RPGRGSVFRLQLPAALMPLPAHPGKPAPALTAQRDLHGLRILLIDDDQRVRDSMAQLLGQ 501 RPGRGSVFR +P L P +P A R L GL++L+IDDD+ +R +M++LL Sbjct: 446 RPGRGSVFRFSMPQTL-DAPEALARP----VAARSLDGLQVLVIDDDEAIRSAMSELLSA 500 Query: 502 WGCHCIDVEGLEEAEALAHSQEFDVVISDYRLRAHRNGTEAIAAVRAASQAHVGALLITG 561 W C C VE E+A A S +V++DYRLR HR G +A+ A+R HV A++ITG Sbjct: 501 WRCECRTVESEEQALAALASFTPALVLADYRLRGHRTGQQALDAIRQRLGRHVPAIIITG 560 Query: 562 DTAPARLREASESGIPMLHKPVAPAQLWEAL 592 DTA RLR A SG +LHKPV P +L A+ Sbjct: 561 DTAADRLRTAHASGTALLHKPVVPQELQAAI 591 >ref|YP_004681300.1| RpfC family transcriptional regulator [Cupriavidus necator N-1] gb|AEI80068.1| transcriptional regulator RpfC family [Cupriavidus necator N-1] Length = 610 Score = 399 bits (1026), Expect = e-109, Method: Composition-based stats. Identities = 254/586 (43%), Positives = 353/586 (60%), Gaps = 9/586 (1%) Query: 22 RVRVEQVRLLCGNLGSSVLPGILVALLVAYALRESAGLWPLLAWAAGVIASKLFDYADAR 81 R+ Q+ L+ + S++L L A ++A L + L WA + + Y R Sbjct: 22 RLLAAQMTLIDQSFSSAMLGCSLAAFILATGLTLTGNRPGALPWACAMALACAIAYF-GR 80 Query: 82 RMLRMEITPANIDQIKRRLVVLHGIDGAAWGLLAPLALDTASPGGSILLIGVLAGVAGNS 141 L ++ A + R + + + GA WGL+A L LD P I ++ ++AG++ + Sbjct: 81 LRLPGRLSEAGAGRYARGMTAMLTLIGALWGLVAWLYLDVRQPAVVICVLSLIAGMSAAA 140 Query: 142 MSILSPVLPAFVSFCLVELGMLAASAWHTHEDALEVLAVAALLYVASLMVQARNSAGAAR 201 +++ S LP + F L + + + T + + + LY+ L+V ARN A AR Sbjct: 141 LAVFSACLPVAIGFFLPAIVPVWIAFLATGDIEYLPMFLGTPLYLCVLLVFARNYARVAR 200 Query: 202 AAIMLRFENNALIERLQRESEKTQQALQQAEQANAAKSRFLAGASHDLRQPIHAQGLFLE 261 AI LRFEN LI +L+ ++ + + A AE A+ AKS FLA ASHDLRQP+HA GLFL Sbjct: 201 HAIALRFENVELISQLREQTARAEAAQHAAEDASRAKSVFLASASHDLRQPLHAMGLFLV 260 Query: 262 VLSNTPLDPMQREVVGRLRNAADNCADMLHTLLDYSRIEAGVVTPQLAPFRPQALIHRIS 321 L T LD QR++V + ++ +ML++LLD+S++EAGV+TP+ FR Q L+H++ Sbjct: 261 SLGRTGLDERQRQLVAHIEASSSAAREMLNSLLDFSKLEAGVITPRARAFRLQPLLHKLE 320 Query: 322 REMAAQAEARGLVFRTRESQAVASADAGLTELILRNLVSNAIRYTERGGVLVACRQRGPQ 381 E A QA+ARGLV+RTR++ A+ D L EL+LRNL++NAIRY+ +GGVLVACR R Sbjct: 321 NEFAPQADARGLVYRTRDTTAMLYGDPTLVELVLRNLIANAIRYSRQGGVLVACRMRRLH 380 Query: 382 VWLEVWDTGIGIAPEQQQEIFREFHQLGNPERDHNKGMGLGLAIAEGLAKMQGLQLTVQS 441 +EVWDTGIGI Q ++IFREFHQLGNPERD KG+GLGLAI +GLA+ ++T+ S Sbjct: 381 AVVEVWDTGIGIPAAQHRDIFREFHQLGNPERDQRKGLGLGLAIVDGLARTMRTRVTLGS 440 Query: 442 RPGRGSVFRLQLPAALMPLPAHPGKPAPALTAQRDLHGLRILLIDDDQRVRDSMAQLLGQ 501 RPGRGSVFR MPL + AP A L GLR+L+IDDD +R +M++LL Sbjct: 441 RPGRGSVFRFN-----MPLAWGTPEEAPRPPAPHGLDGLRVLVIDDDAAIRTAMSELLAA 495 Query: 502 WGCHCIDVEGLEEAEALAHSQEFDVVISDYRLRAHRNGTEAIAAVRAASQAHVGALLITG 561 W C C E EEA AL + ++++DYRLR HR G EA+ A+R HV A++ITG Sbjct: 496 WQCECRTAESEEEALALLSAFTPALILADYRLRGHRTGQEALDAIRQRLGRHVPAIIITG 555 Query: 562 DTAPARLREASESGIPMLHKPVAPAQLWEA---LLRLAAKAGGVHP 604 DTA RLR A SG +LHKPV P +L A LLR A G +P Sbjct: 556 DTAADRLRTAHASGTALLHKPVVPQELQAAIDTLLRDPAAQGEGNP 601