BLASTP 2.2.17 [Aug-26-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= 0001.0377.p (339 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003773585.1| delta-aminolevulinic acid dehydratase [Herba... 642 0.0 ref|YP_004751095.1| porphobilinogen synthase [Collimonas fungivo... 548 e-154 ref|YP_001101366.1| delta-aminolevulinic acid dehydratase [Hermi... 542 e-152 ref|YP_001355068.1| delta-aminolevulinic acid dehydratase [Janth... 538 e-151 ref|ZP_02375467.1| delta-aminolevulinic acid dehydratase [Burkho... 521 e-146 >ref|YP_003773585.1| delta-aminolevulinic acid dehydratase [Herbaspirillum seropedicae SmR1] gb|ADJ61677.1| delta-aminolevulinic acid dehydratase protein [Herbaspirillum seropedicae SmR1] Length = 339 Score = 642 bits (1657), Expect = 0.0, Method: Composition-based stats. Identities = 337/339 (99%), Positives = 338/339 (99%) Query: 1 MSLTDFSSNAGYPALRMRRMRRDAFSRALMAENVITSADLIYPVFVQEGQNLRTPVASLP 60 MSLTDFSSNAGYPALRMRRMRRDAFSRALMAENVITSADLIYPVFVQEGQNLRTPVASLP Sbjct: 1 MSLTDFSSNAGYPALRMRRMRRDAFSRALMAENVITSADLIYPVFVQEGQNLRTPVASLP 60 Query: 61 GVERLSLDTLLPVAEECVKLGVPVLALFPVIDPALKTPDGIEATNPDGLVPRVVRALKDR 120 GVERLSLDTLLPVAEECVKLGVPVLALFPVIDPALKTPDGIEATNPDGLVPRVVRALKDR Sbjct: 61 GVERLSLDTLLPVAEECVKLGVPVLALFPVIDPALKTPDGIEATNPDGLVPRVVRALKDR 120 Query: 121 FPELGVLCDVALDPYTSHGQDGVLDETGYILNDETIALLVKQAQTQADAGVDVVAPSDMM 180 FPELGVLCDVALDPYTSHGQDGVLDETGYILNDET+ALLVKQAQTQADAGVDVVAPSDMM Sbjct: 121 FPELGVLCDVALDPYTSHGQDGVLDETGYILNDETLALLVKQAQTQADAGVDVVAPSDMM 180 Query: 181 DGRIAAIRAMLEAQGHIYTRIMAYSAKYASAFYGPFRDAVGSAANLGKGSKATYQMDPAN 240 DGRIAAIRAMLEAQ HIYTRIMAYSAKYASAFYGPFRDAVGSAANLGKGSKATYQMDPAN Sbjct: 181 DGRIAAIRAMLEAQDHIYTRIMAYSAKYASAFYGPFRDAVGSAANLGKGSKATYQMDPAN 240 Query: 241 SDEALREVALDLQEGADMVMVKPGMPYLDIVRRVKDEFRVPTFAYQVSGEYAMIKAAAQN 300 SDEALREVALDLQEGADMVMVKPGMPYLDIVRRVKDEFRVPTFAYQVSGEYAMIKAAAQN Sbjct: 241 SDEALREVALDLQEGADMVMVKPGMPYLDIVRRVKDEFRVPTFAYQVSGEYAMIKAAAQN 300 Query: 301 GWLDHDKTMMEAMMAFKRAGADGVLTYFALDIARKLKQG 339 GWLDHDKTMMEAMMAFKRAGADGVLTYFALDIARKLKQG Sbjct: 301 GWLDHDKTMMEAMMAFKRAGADGVLTYFALDIARKLKQG 339 >ref|YP_004751095.1| porphobilinogen synthase [Collimonas fungivorans Ter331] gb|AEK60272.1| Porphobilinogen synthase [Collimonas fungivorans Ter331] Length = 398 Score = 548 bits (1411), Expect = e-154, Method: Composition-based stats. Identities = 271/330 (82%), Positives = 298/330 (90%) Query: 10 AGYPALRMRRMRRDAFSRALMAENVITSADLIYPVFVQEGQNLRTPVASLPGVERLSLDT 69 A +PA+RMRRMR+DAFSRA+M EN IT+ADLIYPVF+ +G+N R + S+PGVERLS+D Sbjct: 69 AQFPAIRMRRMRKDAFSRAMMRENTITTADLIYPVFILDGKNQREKINSMPGVERLSIDL 128 Query: 70 LLPVAEECVKLGVPVLALFPVIDPALKTPDGIEATNPDGLVPRVVRALKDRFPELGVLCD 129 LL VAEECV LG+PV+ALFPVI+P+LKTPDGIEATNP GL+PR VR LK RFPELG+L D Sbjct: 129 LLNVAEECVALGIPVIALFPVINPSLKTPDGIEATNPQGLIPRAVRELKQRFPELGILTD 188 Query: 130 VALDPYTSHGQDGVLDETGYILNDETIALLVKQAQTQADAGVDVVAPSDMMDGRIAAIRA 189 VALDPYTSHGQDGVL+ GY+LNDET A+LVKQA TQADAGVD+VAPSDMMDGRI AIR Sbjct: 189 VALDPYTSHGQDGVLNADGYVLNDETCAILVKQALTQADAGVDIVAPSDMMDGRIGAIRH 248 Query: 190 MLEAQGHIYTRIMAYSAKYASAFYGPFRDAVGSAANLGKGSKATYQMDPANSDEALREVA 249 LE HIYTRIMAYSAKYASAFYGPFRDAVGS+A LGK +K TYQMDPANS+EAL EVA Sbjct: 249 ALETHHHIYTRIMAYSAKYASAFYGPFRDAVGSSATLGKSNKNTYQMDPANSNEALHEVA 308 Query: 250 LDLQEGADMVMVKPGMPYLDIVRRVKDEFRVPTFAYQVSGEYAMIKAAAQNGWLDHDKTM 309 LDL EGADMVMVKPGMPYLDIVRRVKDEF+VPTFAYQVSGEYAMIKAAAQNGWLDHDKTM Sbjct: 309 LDLAEGADMVMVKPGMPYLDIVRRVKDEFKVPTFAYQVSGEYAMIKAAAQNGWLDHDKTM 368 Query: 310 MEAMMAFKRAGADGVLTYFALDIARKLKQG 339 MEAM+AFKRAGADGVLTYFALDIAR LK+G Sbjct: 369 MEAMLAFKRAGADGVLTYFALDIARHLKKG 398 >ref|YP_001101366.1| delta-aminolevulinic acid dehydratase [Herminiimonas arsenicoxydans] emb|CAL63245.1| Delta-aminolevulinic acid dehydratase (Porphobilinogen synthase) (ALAD) (ALADH) [Herminiimonas arsenicoxydans] Length = 337 Score = 542 bits (1397), Expect = e-152, Method: Composition-based stats. Identities = 272/337 (80%), Positives = 299/337 (88%) Query: 3 LTDFSSNAGYPALRMRRMRRDAFSRALMAENVITSADLIYPVFVQEGQNLRTPVASLPGV 62 ++ F SNA +PA+RMRRMR+DAFSRA+M ENV+T ADLIYPVFV EG+N ++S+PGV Sbjct: 1 MSKFLSNAQFPAVRMRRMRKDAFSRAMMRENVLTPADLIYPVFVTEGKNQSEKISSMPGV 60 Query: 63 ERLSLDTLLPVAEECVKLGVPVLALFPVIDPALKTPDGIEATNPDGLVPRVVRALKDRFP 122 ERLS+D LL VAEECV L +PVLALFPVI+ +LKTPDGIEA NPDGLVPR VR LK FP Sbjct: 61 ERLSVDLLLSVAEECVSLHIPVLALFPVINASLKTPDGIEACNPDGLVPRAVRELKKHFP 120 Query: 123 ELGVLCDVALDPYTSHGQDGVLDETGYILNDETIALLVKQAQTQADAGVDVVAPSDMMDG 182 ELG+L D+ALDPYTSHGQDGVLD GY+LNDET ++L KQA T A+AGVD+VAPSDMMDG Sbjct: 121 ELGILTDIALDPYTSHGQDGVLDANGYVLNDETCSILTKQALTHAEAGVDIVAPSDMMDG 180 Query: 183 RIAAIRAMLEAQGHIYTRIMAYSAKYASAFYGPFRDAVGSAANLGKGSKATYQMDPANSD 242 RI AIR LEA HIYTRIMAYSAKYASAFYGPFRDAVGS+A LGK +KATYQMDPANSD Sbjct: 181 RIGAIRNALEAHHHIYTRIMAYSAKYASAFYGPFRDAVGSSATLGKSNKATYQMDPANSD 240 Query: 243 EALREVALDLQEGADMVMVKPGMPYLDIVRRVKDEFRVPTFAYQVSGEYAMIKAAAQNGW 302 EALREVALDL EGADMVMVKPGMPYLDIVRRVKDEF+VPTFAYQVSGEYAMIKAAAQ GW Sbjct: 241 EALREVALDLAEGADMVMVKPGMPYLDIVRRVKDEFKVPTFAYQVSGEYAMIKAAAQQGW 300 Query: 303 LDHDKTMMEAMMAFKRAGADGVLTYFALDIARKLKQG 339 LDHDKTMMEAM+AFKRAGADGVLTYFA DIAR+LK G Sbjct: 301 LDHDKTMMEAMIAFKRAGADGVLTYFARDIARRLKLG 337 >ref|YP_001355068.1| delta-aminolevulinic acid dehydratase [Janthinobacterium sp. Marseille] gb|ABR88657.1| porphobilinogen synthase [Janthinobacterium sp. Marseille] Length = 337 Score = 538 bits (1387), Expect = e-151, Method: Composition-based stats. Identities = 270/337 (80%), Positives = 301/337 (89%) Query: 3 LTDFSSNAGYPALRMRRMRRDAFSRALMAENVITSADLIYPVFVQEGQNLRTPVASLPGV 62 ++ NA +PALRMRRMR+DAFSRA+M E+V+T+ADLIYPVF+ EG+N R V+S+PGV Sbjct: 1 MSKLLQNAQFPALRMRRMRKDAFSRAMMREHVVTAADLIYPVFITEGENQREKVSSMPGV 60 Query: 63 ERLSLDTLLPVAEECVKLGVPVLALFPVIDPALKTPDGIEATNPDGLVPRVVRALKDRFP 122 ERLS+D LL VAEECV+L +PV+ALFPVI +LKTPDGIEA NP+GLVPR VR LK RFP Sbjct: 61 ERLSVDLLLSVAEECVELNIPVMALFPVIQASLKTPDGIEACNPNGLVPRAVRELKKRFP 120 Query: 123 ELGVLCDVALDPYTSHGQDGVLDETGYILNDETIALLVKQAQTQADAGVDVVAPSDMMDG 182 ELG+L DVALDPYTSHGQDGVLD GY+LNDET A+L KQA QA+AGVD+VAPSDMMDG Sbjct: 121 ELGILTDVALDPYTSHGQDGVLDAHGYVLNDETCAILTKQALAQAEAGVDIVAPSDMMDG 180 Query: 183 RIAAIRAMLEAQGHIYTRIMAYSAKYASAFYGPFRDAVGSAANLGKGSKATYQMDPANSD 242 RI AIR+ LE+ HIYTRIMAYSAKYASAFYGPFRDAVGS+A LGK +K+TYQMDPANSD Sbjct: 181 RIGAIRSALESHHHIYTRIMAYSAKYASAFYGPFRDAVGSSATLGKSNKSTYQMDPANSD 240 Query: 243 EALREVALDLQEGADMVMVKPGMPYLDIVRRVKDEFRVPTFAYQVSGEYAMIKAAAQNGW 302 EALREVALDL EGADMVMVKPGMPYLDIVRRVKDEF+VPTFAYQVSGEYAMIKAAAQ GW Sbjct: 241 EALREVALDLAEGADMVMVKPGMPYLDIVRRVKDEFKVPTFAYQVSGEYAMIKAAAQQGW 300 Query: 303 LDHDKTMMEAMMAFKRAGADGVLTYFALDIARKLKQG 339 LDHDKTMMEAM+AFKRAGADGVLTYFA DIAR+LK G Sbjct: 301 LDHDKTMMEAMIAFKRAGADGVLTYFARDIARRLKLG 337 >ref|ZP_02375467.1| delta-aminolevulinic acid dehydratase [Burkholderia thailandensis TXDOH] Length = 332 Score = 521 bits (1343), Expect = e-146, Method: Composition-based stats. Identities = 256/326 (78%), Positives = 294/326 (90%) Query: 12 YPALRMRRMRRDAFSRALMAENVITSADLIYPVFVQEGQNLRTPVASLPGVERLSLDTLL 71 +P R RRMRRD FSR LM EN++T+ DLIYPVFV EG N+R PV S+PGVER+S+D L+ Sbjct: 4 HPLHRPRRMRRDDFSRRLMRENILTTNDLIYPVFVVEGTNVRQPVPSMPGVERVSVDLLM 63 Query: 72 PVAEECVKLGVPVLALFPVIDPALKTPDGIEATNPDGLVPRVVRALKDRFPELGVLCDVA 131 VAE+CV+LGVPVL+LFP I+P+LKTPDG EATNP+GL+PR VR LK RFPELGVL DVA Sbjct: 64 GVAEQCVELGVPVLSLFPAIEPSLKTPDGREATNPEGLIPRAVRELKQRFPELGVLTDVA 123 Query: 132 LDPYTSHGQDGVLDETGYILNDETIALLVKQAQTQADAGVDVVAPSDMMDGRIAAIRAML 191 LDPYTSHGQDGVLDE GY+LNDET+ +LV+QA+ QA+AGVD+VAPSDMMDGRI A+R ML Sbjct: 124 LDPYTSHGQDGVLDEAGYVLNDETVEILVEQARAQAEAGVDIVAPSDMMDGRIGAVREML 183 Query: 192 EAQGHIYTRIMAYSAKYASAFYGPFRDAVGSAANLGKGSKATYQMDPANSDEALREVALD 251 E++GHIYTRIMAYSAKYASAFYGPFRDAVGSA+NLGKG+K TYQMDPANSDEALREV LD Sbjct: 184 ESEGHIYTRIMAYSAKYASAFYGPFRDAVGSASNLGKGNKMTYQMDPANSDEALREVRLD 243 Query: 252 LQEGADMVMVKPGMPYLDIVRRVKDEFRVPTFAYQVSGEYAMIKAAAQNGWLDHDKTMME 311 + EGADMVMVKPGMPYLDIVRRVKDEFR PT+ YQVSGEYAM+KAAAQNGWLDHDK ++E Sbjct: 244 IDEGADMVMVKPGMPYLDIVRRVKDEFRFPTYVYQVSGEYAMLKAAAQNGWLDHDKVVLE 303 Query: 312 AMMAFKRAGADGVLTYFALDIARKLK 337 +++AFKRAGADG+LTYFALD AR L+ Sbjct: 304 SLLAFKRAGADGILTYFALDAARLLR 329