BLASTP 2.2.17 [Aug-26-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= 0001.0319.p (457 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_557664.1| major facilitator superfamily multidrug efflux ... 376 e-102 ref|YP_001120314.1| major facilitator transporter [Burkholderia ... 370 e-100 ref|YP_003604428.1| major facilitator superfamily MFS_1 [Burkhol... 369 e-100 ref|YP_001894780.1| major facilitator superfamily protein [Burkh... 369 e-100 ref|YP_369955.1| major facilitator transporter [Burkholderia sp.... 368 1e-99 >ref|YP_557664.1| major facilitator superfamily multidrug efflux transporter [Burkholderia xenovorans LB400] gb|ABE29612.1| Major facilitator superfamily (MFS) multidrug efflux pump [Burkholderia xenovorans LB400] Length = 474 Score = 376 bits (966), Expect = e-102, Method: Composition-based stats. Identities = 233/457 (50%), Positives = 314/457 (68%), Gaps = 3/457 (0%) Query: 2 AVTSASSSTSPDHHD-GLPPRQRLLAIATVVLGLSIAVLDGSIANLALPVMATDLKASDA 60 A T A +++PD+ + GLP R A+ + L L++AVLD +IAN+ALP +A +L+AS A Sbjct: 17 ADTLAPDTSTPDNTEQGLPVPHRYWAMLVIALALTLAVLDSAIANVALPTIARNLRASAA 76 Query: 61 DAIWVINSYQIAMAVCLLPLASLGEVIGYRRVYLGGLFLFTLASLACAASGDMLQLSLAR 120 +IWV+N+YQ+A+ + LLPLASLG+ IGYRR+YLGGL LFTLASL CA S + L+LAR Sbjct: 77 GSIWVVNAYQLAITISLLPLASLGDRIGYRRIYLGGLILFTLASLGCALSTSLSTLALAR 136 Query: 121 VLQGLGAAGILSVNTALIRFIYPARQLGRAIGYNALVAGTGNALGPTVAGVILHLGSWHW 180 V+QG GAAGI+SVNTAL+R IYP QLGR + NA+V +A+GPTVA +L + SW W Sbjct: 137 VIQGFGAAGIMSVNTALVRMIYPRTQLGRGVAINAMVVAVSSAVGPTVASGVLAIASWPW 196 Query: 181 LFLINIPLGLAALAVGSRALPFNPLSARRFDRQSALLCMAFIGLLLYTIDAIGHLQG-GW 239 LF IN+P+G+AA+ G +ALP N +D SA++ GLL++ +D +GH + G+ Sbjct: 197 LFAINVPIGIAAIVGGFKALPMNRGHESPYDYLSAVMNAFVFGLLIFAVDGLGHGERFGY 256 Query: 240 VVAGCALLTAISLALLLKLQSPSAPMLPLDLLRIPLFALSIGTSFCSFAAQMAVFVMLPF 299 V I + + + AP+LP+DLLRIP+FALSIGTS CSF AQM FV LPF Sbjct: 257 VAIEVIAAVVIGYFFVRRQLTQPAPLLPVDLLRIPVFALSIGTSICSFCAQMLAFVSLPF 316 Query: 300 MLQNHLGMGAARAGLLLTAWPVAVALTGVMAGKLSDRIAAGLLGGIGLAVMCLGLLSLLL 359 +LQ LG GLL+T WP + + +AG LSD++++G LGGIGLA M GL+ L Sbjct: 317 LLQETLGFSQVDTGLLMTPWPAVIIVAAPIAGLLSDKVSSGWLGGIGLAAMTAGLILLAT 376 Query: 360 VQPGTPDGVMVAMFALCGVGFGLFQSPNNRTMISAAPRERTGGASGMLGTARLTGQTVGA 419 + P + ALCG GFG+FQSPNNRT++SAAPRER+GGASGMLGTARLTGQT+GA Sbjct: 377 LGPHPDVMQITWRMALCGAGFGIFQSPNNRTILSAAPRERSGGASGMLGTARLTGQTLGA 436 Query: 420 SVVAMLMGFSG-SPYALVLCFAAALAGAASLVSLSRL 455 ++VA++ G + +VL AA + A+++S R+ Sbjct: 437 ALVALIFGIAPLHGPTIVLYVAACFSAVAAVISTLRV 473 >ref|YP_001120314.1| major facilitator transporter [Burkholderia vietnamiensis G4] gb|ABO55479.1| major facilitator superfamily MFS_1 [Burkholderia vietnamiensis G4] Length = 473 Score = 370 bits (951), Expect = e-100, Method: Composition-based stats. Identities = 227/416 (54%), Positives = 292/416 (70%), Gaps = 5/416 (1%) Query: 17 GLPPRQRLLAIATVVLGLSIAVLDGSIANLALPVMATDLKASDADAIWVINSYQIAMAVC 76 GLP QR AI V LG+++AVLDG+IAN+ALP +A DL ASDA +IW++N+YQ+A+ + Sbjct: 24 GLPLPQRYWAIVCVALGITLAVLDGAIANVALPTIARDLHASDAASIWIVNAYQLAVTIT 83 Query: 77 LLPLASLGEVIGYRRVYLGGLFLFTLASLACAASGDMLQLSLARVLQGLGAAGILSVNTA 136 LLPLASLGE IGYRRVY+ GL +FT ASL CA SG + L++ RV+QG GAAGI+SVN A Sbjct: 84 LLPLASLGERIGYRRVYISGLAVFTAASLGCALSGSLPTLAVMRVIQGFGAAGIMSVNAA 143 Query: 137 LIRFIYPARQLGRAIGYNALVAGTGNALGPTVAGVILHLGSWHWLFLINIPLGLAALAVG 196 L+R IYP+ LGR + NA+V +A+GPTVA IL SW WLF +N+P+G+AA+ Sbjct: 144 LVRMIYPSSMLGRGLSINAMVVALSSAIGPTVASAILSFASWPWLFAVNVPIGIAAVFGS 203 Query: 197 SRALPFNPLSARRFDRQSALLCMAFIGLLLYTIDAIGHLQG-GWVVAGCALLTAISLALL 255 RALP NPL +D SAL+ GLL+ +D +GH + +V A A+ I + Sbjct: 204 VRALPANPLHDAPYDFASALMNACVFGLLIMAVDGLGHGESRAYVAAELAVALGIGYFFV 263 Query: 256 LKLQSPSAPMLPLDLLRIPLFALSIGTSFCSFAAQMAVFVMLPFMLQNHLGMGAARAGLL 315 + S AP+LP+DL+RIP+FALSIGTS SF +QM FV LPF LQ+ LG GL Sbjct: 264 KRQLSQPAPLLPVDLMRIPMFALSIGTSVASFTSQMLAFVALPFWLQHSLGFSQVETGLF 323 Query: 316 LTAWPVAVALTGVMAGKLSDRIAAGLLGGIGLAVMCLGLLSLLLV--QPGTPDGVMVAMF 373 +T WP+ + +AG LSDR +AG+LGGIGLA+ GLLSL + PGT D +V Sbjct: 324 MTPWPLVIVFAAPLAGVLSDRYSAGILGGIGLALFAAGLLSLATIGAHPGTVD--IVWRM 381 Query: 374 ALCGVGFGLFQSPNNRTMISAAPRERTGGASGMLGTARLTGQTVGASVVAMLMGFS 429 ALCG GFGLFQSPNNR M+S+APRER+GGA GML TARLTGQT+GA++VA++ G + Sbjct: 382 ALCGAGFGLFQSPNNRAMLSSAPRERSGGAGGMLSTARLTGQTLGAALVALIFGVA 437 >ref|YP_003604428.1| major facilitator superfamily MFS_1 [Burkholderia sp. CCGE1002] gb|ADG14917.1| major facilitator superfamily MFS_1 [Burkholderia sp. CCGE1002] Length = 472 Score = 369 bits (948), Expect = e-100, Method: Composition-based stats. Identities = 230/442 (52%), Positives = 310/442 (70%), Gaps = 4/442 (0%) Query: 17 GLPPRQRLLAIATVVLGLSIAVLDGSIANLALPVMATDLKASDADAIWVINSYQIAMAVC 76 GLP QR A+ + L L++AVLD +IAN+ALP +A +L AS A +IWV+N+YQ+A+ + Sbjct: 24 GLPVPQRYWAMLVIALSLTLAVLDSAIANVALPTIARNLNASAAASIWVVNAYQLAITIS 83 Query: 77 LLPLASLGEVIGYRRVYLGGLFLFTLASLACAASGDMLQLSLARVLQGLGAAGILSVNTA 136 LLP+ASLG+ IGYRR+YL GL LFT+ASL CA S + L+LARV+QG GAAGI+SVNTA Sbjct: 84 LLPMASLGDRIGYRRIYLSGLILFTVASLGCALSNSLATLALARVVQGFGAAGIMSVNTA 143 Query: 137 LIRFIYPARQLGRAIGYNALVAGTGNALGPTVAGVILHLGSWHWLFLINIPLGLAALAVG 196 ++R IYP QLGR + NA+V +A+GPTVA +L + +W WLF IN+P+G+AA+ G Sbjct: 144 IVRMIYPPAQLGRGVSINAMVVAVSSAVGPTVASGVLAIATWPWLFAINVPIGIAAIVGG 203 Query: 197 SRALPFNPLSARRFDRQSALLCMAFIGLLLYTIDAIGHLQG-GWVVAGCALLTAISLALL 255 +ALP NP +D SA++ GLL++ +D +GH Q G+V + + Sbjct: 204 FKALPMNPGHESPYDYLSAVMNAFVFGLLIFAVDGLGHGQRLGYVTLEALGALVVGYFFV 263 Query: 256 LKLQSPSAPMLPLDLLRIPLFALSIGTSFCSFAAQMAVFVMLPFMLQNHLGMGAARAGLL 315 + + AP+LP+DLLRIP+FALSIGTS CSF AQM FV LPF+LQ LGM GLL Sbjct: 264 RRQLTRPAPLLPIDLLRIPVFALSIGTSVCSFCAQMLAFVSLPFLLQETLGMSQVETGLL 323 Query: 316 LTAWPVAVALTGVMAGKLSDRIAAGLLGGIGLAVMCLGLLSLLLVQPGTPDGVMVA-MFA 374 +T WP + + +AG LSDRI++G LGG+GLA M +GLL L + P PD + ++ A Sbjct: 324 MTPWPAIIIIAAPIAGVLSDRISSGWLGGVGLAAMTVGLLLLATLGP-HPDALQISWRMA 382 Query: 375 LCGVGFGLFQSPNNRTMISAAPRERTGGASGMLGTARLTGQTVGASVVAMLMGFS-GSPY 433 LCG GFG+FQSPNNRT++S+APRER+GGASGMLGTARLTGQT+GA++VA++ G + S Sbjct: 383 LCGAGFGIFQSPNNRTILSSAPRERSGGASGMLGTARLTGQTLGAALVALIFGVAPQSGT 442 Query: 434 ALVLCFAAALAGAASLVSLSRL 455 + L AA + A++VS R+ Sbjct: 443 VVALYVAAGFSAVAAVVSTMRV 464 >ref|YP_001894780.1| major facilitator superfamily protein [Burkholderia phytofirmans PsJN] gb|ACD15556.1| major facilitator superfamily MFS_1 [Burkholderia phytofirmans PsJN] Length = 485 Score = 369 bits (946), Expect = e-100, Method: Composition-based stats. Identities = 234/450 (52%), Positives = 310/450 (68%), Gaps = 4/450 (0%) Query: 9 STSPDHHDGLPPRQRLLAIATVVLGLSIAVLDGSIANLALPVMATDLKASDADAIWVINS 68 S D GLP QR A+ + L L++AVLD +IAN+ALP +A +L AS A +IWV+N+ Sbjct: 28 SLRDDTEQGLPIPQRYWAMLVIALSLTLAVLDSAIANVALPTIARNLHASAAGSIWVVNA 87 Query: 69 YQIAMAVCLLPLASLGEVIGYRRVYLGGLFLFTLASLACAASGDMLQLSLARVLQGLGAA 128 YQ+A+ + LLPLASLG+ IGYRR+YL GL LFT+AS CA S + L+LARV+QG GAA Sbjct: 88 YQLAITISLLPLASLGDRIGYRRIYLAGLILFTVASFGCALSTSLPTLALARVIQGFGAA 147 Query: 129 GILSVNTALIRFIYPARQLGRAIGYNALVAGTGNALGPTVAGVILHLGSWHWLFLINIPL 188 GI+SVNTAL+R IYP QLGR + NA+V +A+GPTVA +L + SW WLF IN+P+ Sbjct: 148 GIMSVNTALVRMIYPPAQLGRGVSINAMVVAVSSAVGPTVASGVLAVASWPWLFAINVPI 207 Query: 189 GLAALAVGSRALPFNPLSARRFDRQSALLCMAFIGLLLYTIDAIGHLQGGWVVAGCALLT 248 G+AA+ G +ALP NP +D SA++ GLL++ +D +GH +G VA AL Sbjct: 208 GIAAIVGGFKALPMNPGHESPYDYPSAVMNAFVFGLLIFAVDGLGHGEGFGYVALEALGA 267 Query: 249 AISLALLLKLQ-SPSAPMLPLDLLRIPLFALSIGTSFCSFAAQMAVFVMLPFMLQNHLGM 307 + ++ Q + AP+LP+DLLRIP+FALSIGTS CSF AQM FV LPF+LQ+ LG+ Sbjct: 268 LVIGYFFVRRQLTQPAPLLPIDLLRIPIFALSIGTSVCSFCAQMLAFVSLPFLLQDTLGL 327 Query: 308 GAARAGLLLTAWPVAVALTGVMAGKLSDRIAAGLLGGIGLAVMCLGLLSLLLVQPGTPDG 367 GLL+T WP + + +AG LSD++++G LGG+GLA M L LL PD Sbjct: 328 SQVETGLLMTPWPAVIIIAAPIAGVLSDKVSSGWLGGVGLAAM-TAGLLLLATLGAHPDA 386 Query: 368 VMVA-MFALCGVGFGLFQSPNNRTMISAAPRERTGGASGMLGTARLTGQTVGASVVAMLM 426 + +A ALCG GFG+FQSPNNRTM+SAAPRER+GGASGMLGTARLTGQT+GA++VA++ Sbjct: 387 MQIAWRMALCGAGFGIFQSPNNRTMLSAAPRERSGGASGMLGTARLTGQTLGAALVALIF 446 Query: 427 GFSGSPYALV-LCFAAALAGAASLVSLSRL 455 G + V L AA + A+++S R+ Sbjct: 447 GIAPQHGPTVALYVAACFSALAAVISTMRV 476 >ref|YP_369955.1| major facilitator transporter [Burkholderia sp. 383] gb|ABB09311.1| Major facilitator superfamily (MFS_1) transporter [Burkholderia sp. 383] Length = 455 Score = 368 bits (945), Expect = 1e-99, Method: Composition-based stats. Identities = 226/415 (54%), Positives = 291/415 (70%), Gaps = 5/415 (1%) Query: 17 GLPPRQRLLAIATVVLGLSIAVLDGSIANLALPVMATDLKASDADAIWVINSYQIAMAVC 76 GLP QR AI V LG+++AVLDG+IAN+ALP +A DL ASDA +IW++N+YQ+A+ + Sbjct: 6 GLPLPQRYWAIVCVALGITLAVLDGAIANVALPTIARDLHASDAASIWIVNAYQLAVTIT 65 Query: 77 LLPLASLGEVIGYRRVYLGGLFLFTLASLACAASGDMLQLSLARVLQGLGAAGILSVNTA 136 LLPLASLGE IGYRR+Y+ GL LFT ASL CA +G + L++ RV+QG GAAGI+SVN A Sbjct: 66 LLPLASLGERIGYRRIYIAGLALFTAASLGCALAGSLPMLAVMRVIQGFGAAGIMSVNAA 125 Query: 137 LIRFIYPARQLGRAIGYNALVAGTGNALGPTVAGVILHLGSWHWLFLINIPLGLAALAVG 196 L+R IYP+ LGR + NA+V +A+GPTVA IL SW WLF +N+P+G+AA+ Sbjct: 126 LVRMIYPSSMLGRGLSINAMVVALSSAIGPTVASAILSFASWPWLFAVNVPIGIAAVFGS 185 Query: 197 SRALPFNPLSARRFDRQSALLCMAFIGLLLYTIDAIGHLQG-GWVVAGCALLTAISLALL 255 RALP NPL +D SAL+ GLL+ +D +GH +G +V A A+ + + Sbjct: 186 LRALPSNPLHDAPYDFPSALMNACVFGLLITAVDGLGHGEGHAYVAAELAIAFVVGYFFV 245 Query: 256 LKLQSPSAPMLPLDLLRIPLFALSIGTSFCSFAAQMAVFVMLPFMLQNHLGMGAARAGLL 315 + S AP+LP+DL+RIP+FALSI TS SF +QM FV LPF LQN LG GL Sbjct: 246 KRQLSQPAPLLPVDLMRIPMFALSIYTSMASFTSQMLAFVALPFWLQNSLGFSQVETGLY 305 Query: 316 LTAWPVAVALTGVMAGKLSDRIAAGLLGGIGLAVMCLGLLSLLLV--QPGTPDGVMVAMF 373 +T WP+ + +AG LSDR +AG+LGGIGLA+ GLLSL + PGT D +V Sbjct: 306 MTPWPLVIVFAAPLAGVLSDRYSAGILGGIGLALFAAGLLSLATIGAHPGTVD--IVWRM 363 Query: 374 ALCGVGFGLFQSPNNRTMISAAPRERTGGASGMLGTARLTGQTVGASVVAMLMGF 428 ALCG GFGLFQSPNNR M+S+APRER+GGA GML TARLTGQT+GA++VA++ G Sbjct: 364 ALCGAGFGLFQSPNNRAMLSSAPRERSGGAGGMLSTARLTGQTLGAALVALIFGL 418