BLASTP 2.2.17 [Aug-26-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= 0001.0263.p (326 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003775052.1| dehydrogenase oxidoreductase [Herbaspirillum... 606 e-171 ref|YP_001099124.1| putative glyoxylate reductase (glycolate red... 489 e-136 ref|YP_004753703.1| 2-ketoaldonate reductase [Collimonas fungivo... 488 e-136 ref|YP_001352411.1| 2-hydroxyacid dehydrogenase [Janthinobacteri... 475 e-132 ref|YP_001791021.1| D-isomer specific 2-hydroxyacid dehydrogenas... 418 e-115 >ref|YP_003775052.1| dehydrogenase oxidoreductase [Herbaspirillum seropedicae SmR1] emb|CAM32608.1| Dehydrogenase oxidoreductase protein [Herbaspirillum seropedicae] gb|ADJ63144.1| dehydrogenase oxidoreductase protein [Herbaspirillum seropedicae SmR1] Length = 326 Score = 606 bits (1562), Expect = e-171, Method: Composition-based stats. Identities = 315/326 (96%), Positives = 321/326 (98%) Query: 1 MKPKIFVARAVFPEVLARLEQHFEVESNQDDRIYSADELLAKANGKDGLFTTPSEPVTAA 60 MKPKIFVARAVFPEVLARLEQHFEVESNQDDRIYSA EL AKA GKDGLFTTPSEPVTAA Sbjct: 1 MKPKIFVARAVFPEVLARLEQHFEVESNQDDRIYSAAELQAKAQGKDGLFTTPSEPVTAA 60 Query: 61 LFAANPQLKAVCNMAVGYNNIDVAAATKAGVMATNTPDVLNETTADFGWALMMAAARRIT 120 LFAANPQLKAVCNMAVGYNNIDVAAAT+AGVMATNTPDVLNETTADFGWALMMAAARRIT Sbjct: 61 LFAANPQLKAVCNMAVGYNNIDVAAATQAGVMATNTPDVLNETTADFGWALMMAAARRIT 120 Query: 121 ESEHFLRAGKWKKWSYDSFVGPDIHGATLGIIGMGRIGQAIARRSLGFDMQVLYHNRSRL 180 ESEHFLRAGKWKKWSYDSFVGPDIHGATLGIIGMGRIGQAIARRSLGFDMQVLYHNRSRL Sbjct: 121 ESEHFLRAGKWKKWSYDSFVGPDIHGATLGIIGMGRIGQAIARRSLGFDMQVLYHNRSRL 180 Query: 181 APELEARANNARYVSKEELLQQADHVVLVLPYSKDTHHTIAAPELALMKPTATLTNIARG 240 APELEARAN+ARYVSKEELL+QADHV+LVLPYSKDTHHTIAA ELALMKPTATLTNIARG Sbjct: 181 APELEARANHARYVSKEELLRQADHVILVLPYSKDTHHTIAAAELALMKPTATLTNIARG 240 Query: 241 GIVDDAALIAALREGRIAAAGVDVFENEPSFKPEFLDLSNVVLTPHIASASTPTRLAMAN 300 GIVDDAALIAALREGRIAAAGVDVFENEP+FKPEFLDLSNVVLTPHIASASTPTRLAMAN Sbjct: 241 GIVDDAALIAALREGRIAAAGVDVFENEPAFKPEFLDLSNVVLTPHIASASTPTRLAMAN 300 Query: 301 CAAGNLIAALSGQRPPNLLNPDVLKG 326 CAA NLIAALSGQRPPNLLNPDV+KG Sbjct: 301 CAADNLIAALSGQRPPNLLNPDVVKG 326 >ref|YP_001099124.1| putative glyoxylate reductase (glycolate reductase) [Herminiimonas arsenicoxydans] emb|CAL60997.1| putative glyoxylate reductase (Glycolate reductase) [Herminiimonas arsenicoxydans] Length = 327 Score = 489 bits (1260), Expect = e-136, Method: Composition-based stats. Identities = 238/323 (73%), Positives = 276/323 (85%) Query: 1 MKPKIFVARAVFPEVLARLEQHFEVESNQDDRIYSADELLAKANGKDGLFTTPSEPVTAA 60 MK KI VARA FP+V+ RL+Q FEVESNQ+DRI+S EL K GKDG+ T SE ++ Sbjct: 1 MKQKILVARATFPDVIERLQQQFEVESNQEDRIFSPAELHEKMQGKDGVIITSSEKLSGE 60 Query: 61 LFAANPQLKAVCNMAVGYNNIDVAAATKAGVMATNTPDVLNETTADFGWALMMAAARRIT 120 + ANPQLKA+CN+AVGYNNIDVAAATKAG+M TNTPDVLNETTAD+ W L+MA ARR + Sbjct: 61 VITANPQLKAICNVAVGYNNIDVAAATKAGIMVTNTPDVLNETTADYAWTLLMANARRTS 120 Query: 121 ESEHFLRAGKWKKWSYDSFVGPDIHGATLGIIGMGRIGQAIARRSLGFDMQVLYHNRSRL 180 ESEH+LRAGKWK W +D F+G D+HGATLGI+GMGRIGQAIARRS+GFDMQV+YHNRSRL Sbjct: 121 ESEHYLRAGKWKNWRFDQFLGADVHGATLGILGMGRIGQAIARRSMGFDMQVIYHNRSRL 180 Query: 181 APELEARANNARYVSKEELLQQADHVVLVLPYSKDTHHTIAAPELALMKPTATLTNIARG 240 P+ EA ANNARYVSKEELL+ ADH++LVLPYS+ THH I A ELALMKPTATL NIARG Sbjct: 181 TPDQEAHANNARYVSKEELLRTADHLILVLPYSEQTHHIIGAAELALMKPTATLVNIARG 240 Query: 241 GIVDDAALIAALREGRIAAAGVDVFENEPSFKPEFLDLSNVVLTPHIASASTPTRLAMAN 300 GIVDD ALIAALRE RIA+AG+DV+ENEP+ P+FL LSNVVLTPHI SAS TR AM++ Sbjct: 241 GIVDDVALIAALREHRIASAGLDVYENEPALHPDFLTLSNVVLTPHIGSASEKTRRAMSD 300 Query: 301 CAAGNLIAALSGQRPPNLLNPDV 323 CA+ N++AALSGQRPPNLLNP+V Sbjct: 301 CASLNMVAALSGQRPPNLLNPEV 323 >ref|YP_004753703.1| 2-ketoaldonate reductase [Collimonas fungivorans Ter331] gb|AEK62880.1| 2-ketoaldonate reductase, broad specificity [Collimonas fungivorans Ter331] Length = 334 Score = 488 bits (1255), Expect = e-136, Method: Composition-based stats. Identities = 258/328 (78%), Positives = 287/328 (87%), Gaps = 4/328 (1%) Query: 1 MKPKIFVARAVFPEVLARLEQHFEVESNQDDRIYSADELLAKANGKDGLFTTPSEPVTAA 60 MKPKI +ARAVFPEV+A L+QHFEVESNQDDRI+SA EL K + KDG+ T SE ++A Sbjct: 1 MKPKILMARAVFPEVIASLQQHFEVESNQDDRIFSAAELTQKLSDKDGVIATASERISAE 60 Query: 61 LFAANPQLKAVCNMAVGYNNIDVAAATKAGVMATNTPDVLNETTADFGWALMMAAARRIT 120 L A P+LKAVCN AVGYNNIDVAAATKAGVM TNTPDVLNETTADFGWAL+MA ARR+T Sbjct: 61 LLQACPRLKAVCNQAVGYNNIDVAAATKAGVMVTNTPDVLNETTADFGWALLMATARRVT 120 Query: 121 ESEHFLRAGKWKKWSYDSFVGPDIHGATLGIIGMGRIGQAIARRSLGFDMQVLYHNRSRL 180 ESEH+LRAG WK+W YDSF+G D+HGATLGIIGMGRIGQAIARRSLGFDMQVLYHNRSRL Sbjct: 121 ESEHWLRAGHWKQWRYDSFLGADVHGATLGIIGMGRIGQAIARRSLGFDMQVLYHNRSRL 180 Query: 181 APELEARANNARYVSKEELLQQADHVVLVLPYSKDTHHTIAAPELALMKPTATLTNIARG 240 APELEARANNARY KEELL ADHV+LVLPYSK++HHTI A ELALMKP ATL N+ARG Sbjct: 181 APELEARANNARYAGKEELLAAADHVILVLPYSKESHHTIGAAELALMKPGATLVNLARG 240 Query: 241 GIVDDAALIAALREGRIAAAGVDVFENEPSFKPEFLDLSNVVLTPHIASASTPTRLAMAN 300 GIVDD ALIAALR+ RIAAAG+DVFENEP+ P+FL+LSNVVLTPHIASAS PTR AMA+ Sbjct: 241 GIVDDLALIAALRDKRIAAAGLDVFENEPALHPDFLELSNVVLTPHIASASEPTRRAMAD 300 Query: 301 CAAGNLIAAL--SGQR--PPNLLNPDVL 324 CAA NL+AAL + +R PPNLLNP+VL Sbjct: 301 CAAANLLAALLPTAERKWPPNLLNPEVL 328 >ref|YP_001352411.1| 2-hydroxyacid dehydrogenase [Janthinobacterium sp. Marseille] gb|ABR88877.1| 2-hydroxyacid dehydrogenase [Janthinobacterium sp. Marseille] Length = 327 Score = 475 bits (1223), Expect = e-132, Method: Composition-based stats. Identities = 238/323 (73%), Positives = 271/323 (83%) Query: 1 MKPKIFVARAVFPEVLARLEQHFEVESNQDDRIYSADELLAKANGKDGLFTTPSEPVTAA 60 MK K+ VARA FP+V+ RL+Q FEVESNQ+D+I+S ELL K GKD + T SE ++A Sbjct: 1 MKAKVLVARATFPDVIERLQQQFEVESNQEDKIFSPAELLQKMQGKDAVVVTASEKMSAD 60 Query: 61 LFAANPQLKAVCNMAVGYNNIDVAAATKAGVMATNTPDVLNETTADFGWALMMAAARRIT 120 + AANPQLKA+CN+AVGYNNIDVAAAT AGVM TNTPDVLNETTAD+ W L+MA ARR+ Sbjct: 61 VIAANPQLKAICNVAVGYNNIDVAAATAAGVMVTNTPDVLNETTADYAWTLLMANARRVC 120 Query: 121 ESEHFLRAGKWKKWSYDSFVGPDIHGATLGIIGMGRIGQAIARRSLGFDMQVLYHNRSRL 180 ESEH+LRAG WK W +DSF+G DIHGATLGI+GMGRIGQAIARRS GFDM V+YHNRSR Sbjct: 121 ESEHWLRAGNWKHWRFDSFLGADIHGATLGILGMGRIGQAIARRSTGFDMNVIYHNRSRA 180 Query: 181 APELEARANNARYVSKEELLQQADHVVLVLPYSKDTHHTIAAPELALMKPTATLTNIARG 240 PE EA ANNARYVSKEELL+ ADH++LVLPYS THH I A ELALMKPTATL NIARG Sbjct: 181 TPEQEAYANNARYVSKEELLRSADHLILVLPYSPQTHHIIGAAELALMKPTATLVNIARG 240 Query: 241 GIVDDAALIAALREGRIAAAGVDVFENEPSFKPEFLDLSNVVLTPHIASASTPTRLAMAN 300 GIVDD ALIAALRE RIA+AG+DVFENEP+ P+FL LSNVVLTPHI S S TR AMA+ Sbjct: 241 GIVDDVALIAALRENRIASAGLDVFENEPALHPDFLTLSNVVLTPHIGSGSEKTRRAMAD 300 Query: 301 CAAGNLIAALSGQRPPNLLNPDV 323 CA+ NL AA+SGQ+PPNLLNP+V Sbjct: 301 CASANLAAAMSGQQPPNLLNPEV 323 >ref|YP_001791021.1| D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein [Leptothrix cholodnii SP-6] gb|ACB34256.1| D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding [Leptothrix cholodnii SP-6] Length = 332 Score = 418 bits (1075), Expect = e-115, Method: Composition-based stats. Identities = 214/324 (66%), Positives = 255/324 (78%), Gaps = 2/324 (0%) Query: 2 KPKIFVARAVFPEVLARLEQHFEVESNQDDRIYSADELLAKANGKDGLFTTPSEPVTAAL 61 +P++ VARAVFP V+ARL +HF+V+ N+ D ++S EL+ + G D +F T EP+ + Sbjct: 8 RPRLLVARAVFPSVIARLREHFDVQHNEADEVWSRAELIERLQGMDAVFVTTGEPIDRGV 67 Query: 62 FAANPQLKAVCNMAVGYNNIDVAAATKAGVMATNTPDVLNETTADFGWALMMAAARRITE 121 AA PQLKAVC+MAVGYNNIDV A T+ GV+A+N PDVL ETTADFG+ALMMA ARRITE Sbjct: 68 LAACPQLKAVCSMAVGYNNIDVPACTERGVLASNAPDVLTETTADFGFALMMATARRITE 127 Query: 122 SEHFLRAGKWKKWSYDSFVGPDIHGATLGIIGMGRIGQAIARR-SLGFDMQVLYHNRSRL 180 SE FLR G+W KW+ D F G D+HG TLGI+GMGRIGQAIARR +LGF M V+YHNRSRL Sbjct: 128 SERFLRRGEWNKWAVDMFAGQDVHGRTLGILGMGRIGQAIARRGALGFGMPVVYHNRSRL 187 Query: 181 APELEARANNARYVSKEELLQQADHVVLVLPYSKDTHHTIAAPELALMKPTATLTNIARG 240 APELE + AR++ KE+LL+QADH+V+VLPYS +HH+I A ELA MKPTATLTN+ARG Sbjct: 188 APELE-QPLGARWLGKEDLLRQADHLVIVLPYSAQSHHSIGAAELAQMKPTATLTNVARG 246 Query: 241 GIVDDAALIAALREGRIAAAGVDVFENEPSFKPEFLDLSNVVLTPHIASASTPTRLAMAN 300 GIVDDAAL AL+ G IAAAG+DVFE EP P+ LD+ NVVLTPHIASAS PTR AMAN Sbjct: 247 GIVDDAALAQALKSGVIAAAGLDVFEGEPQVHPDLLDVPNVVLTPHIASASLPTRTAMAN 306 Query: 301 CAAGNLIAALSGQRPPNLLNPDVL 324 AA NLIA +G PP LNP VL Sbjct: 307 LAADNLIACFTGGTPPTALNPQVL 330