BLASTP 2.2.17 [Aug-26-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= 0001.0034.p (546 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003778167.1| methylmalonate-semialdehyde dehydrogenase [H... 951 0.0 ref|YP_004755057.1| methylmalonate-semialdehyde dehydrogenase [C... 836 0.0 ref|YP_001355332.1| methylmalonate-semialdehyde dehydrogenase [J... 798 0.0 ref|YP_001101643.1| methylmalonate-semialdehyde dehydrogenase, o... 791 0.0 ref|YP_004750751.1| methylmalonate-semialdehyde dehydrogenase [C... 772 0.0 >ref|YP_003778167.1| methylmalonate-semialdehyde dehydrogenase [Herbaspirillum seropedicae SmR1] gb|ADJ66259.1| methylmalonate-semialdehyde dehydrogenase protein [Herbaspirillum seropedicae SmR1] Length = 503 Score = 951 bits (2459), Expect = 0.0, Method: Composition-based stats. Identities = 498/503 (99%), Positives = 502/503 (99%), Gaps = 1/503 (0%) Query: 45 MSLPHIDHFINGQISRSESGRSEDVFNPATGAATAKVSLASVQEVNAAVAAASAAAPAWA 104 MSLPHIDHFINGQISRSESGRS+DVFNPATGAATAKV+LASVQEVNAAVAAASAAAPAWA Sbjct: 1 MSLPHIDHFINGQISRSESGRSQDVFNPATGAATAKVALASVQEVNAAVAAASAAAPAWA 60 Query: 105 ETAPLKRARVLFKFKELIEQNHDALAKAITLEHGKVFSDAKGEVTRGLEIVEFATGIPQL 164 ETAPLKRARVLFKFKELIEQNHDALAKAITLEHGKVFSDAKGEVTRGLEIVEFATGIPQL Sbjct: 61 ETAPLKRARVLFKFKELIEQNHDALAKAITLEHGKVFSDAKGEVTRGLEIVEFATGIPQL 120 Query: 165 LKTQFTDNIGGGIDNWNLRQPLGVTAGITPFNFPVMVPLWMAPIAIATGNSFVLKPSERD 224 LKTQFTDNIGGGIDNWNLRQPLGVTAGITPFNFPVMVPLWMAPIAIATGNSFVLKPSERD Sbjct: 121 LKTQFTDNIGGGIDNWNLRQPLGVTAGITPFNFPVMVPLWMAPIAIATGNSFVLKPSERD 180 Query: 225 PSPSLMLAELFKRAGLPDGVFNVVQGDKVAVDALLEHPEVQAVSFVGSTPIAEYIYRKAT 284 PSPSLMLAELFKRAGLPDGVFNVVQGDKVAVDALLEHPEVQAVSFVGSTPIAEYIYRKAT Sbjct: 181 PSPSLMLAELFKRAGLPDGVFNVVQGDKVAVDALLEHPEVQAVSFVGSTPIAEYIYRKAT 240 Query: 285 ERAGTFPLRAQALGGAKNHLVVMPDANLEQAVDALIGAAYGSAGERCMAISVAVAVGSVA 344 ERAGTFPLRAQALGGAKNHLVVMPDANL+QAVDALIGAAYGSAGERCMAISVAVAVGSVA Sbjct: 241 ERAGTFPLRAQALGGAKNHLVVMPDANLDQAVDALIGAAYGSAGERCMAISVAVAVGSVA 300 Query: 345 DKLVEALIPRVKALKVKNGMEDDAEMGPLVTAAHKAKVEGYIQSGVDAGAKLLVDGRGLK 404 DKLVEALIPRVKALKVKNGMEDDAEMGPLVTAAHKAKVEGYIQSGVDAGAKLLVDGRGLK Sbjct: 301 DKLVEALIPRVKALKVKNGMEDDAEMGPLVTAAHKAKVEGYIQSGVDAGAKLLVDGRGLK 360 Query: 405 VPGHEEGFF-GGTLFDNVTTEMKIYQEEIFGPVLCVVRVPDFASAVQLINAHEYGNGVSL 463 VPGHEEGFF GGTLFD+VTTEMKIYQEEIFGPVLCVVRVPDFASAVQLINAHEYGNGVSL Sbjct: 361 VPGHEEGFFIGGTLFDHVTTEMKIYQEEIFGPVLCVVRVPDFASAVQLINAHEYGNGVSL 420 Query: 464 FTADGNTAHEFSRRIQVGMVGINVPIPVPMAWHSFGGWKRSLFGDTHAYGEEGIRFYTRY 523 FTADGNTAHEFSRRIQVGMVGINVPIPVPMAWHSFGGWKRSLFGDTHAYGEEGIRFYTRY Sbjct: 421 FTADGNTAHEFSRRIQVGMVGINVPIPVPMAWHSFGGWKRSLFGDTHAYGEEGIRFYTRY 480 Query: 524 KSIMQRWSATIGKGAEFTMPVAK 546 KSIMQRWSATIGKGAEFTMPVAK Sbjct: 481 KSIMQRWSATIGKGAEFTMPVAK 503 >ref|YP_004755057.1| methylmalonate-semialdehyde dehydrogenase [Collimonas fungivorans Ter331] gb|AEK64234.1| methylmalonate-semialdehyde dehydrogenase, oxidoreductase protein [Collimonas fungivorans Ter331] Length = 506 Score = 836 bits (2160), Expect = 0.0, Method: Composition-based stats. Identities = 417/500 (83%), Positives = 462/500 (92%), Gaps = 1/500 (0%) Query: 48 PHIDHFINGQISRSESGRSEDVFNPATGAATAKVSLASVQEVNAAVAAASAAAPAWAETA 107 P I H+ING+++ S SGR +DVFNPATGA +A+V L SV+EVN+AVAAASAAA WA+TA Sbjct: 7 PLIQHYINGKVAESTSGRLQDVFNPATGAVSARVVLGSVEEVNSAVAAASAAASGWADTA 66 Query: 108 PLKRARVLFKFKELIEQNHDALAKAITLEHGKVFSDAKGEVTRGLEIVEFATGIPQLLKT 167 PLKRARV+F+FKEL+EQ+HDALA AIT EHGKVFSDAKGEVTRGLEIVEFA G+P LLKT Sbjct: 67 PLKRARVMFRFKELMEQHHDALAAAITREHGKVFSDAKGEVTRGLEIVEFACGVPHLLKT 126 Query: 168 QFTDNIGGGIDNWNLRQPLGVTAGITPFNFPVMVPLWMAPIAIATGNSFVLKPSERDPSP 227 QFTDNIGGGIDNWNLRQPLGVTAGITPFNFPVMVPLWMAP+AIATGN+F+LKPSERDPSP Sbjct: 127 QFTDNIGGGIDNWNLRQPLGVTAGITPFNFPVMVPLWMAPMAIATGNTFILKPSERDPSP 186 Query: 228 SLMLAELFKRAGLPDGVFNVVQGDKVAVDALLEHPEVQAVSFVGSTPIAEYIYRKATERA 287 SLM+AELF +AGLPDGVFNVVQGDK+AVD LL+HP+V+AVSFVGSTPIAEYIY++ R Sbjct: 187 SLMMAELFHQAGLPDGVFNVVQGDKLAVDTLLQHPDVKAVSFVGSTPIAEYIYQEGARRK 246 Query: 288 GTFPLRAQALGGAKNHLVVMPDANLEQAVDALIGAAYGSAGERCMAISVAVAVGSVADKL 347 G +PLR QALGGAKNHLVVMPDA+L+QAVDAL+GAAYGSAGERCMAISVAVAVG+VADKL Sbjct: 247 GAYPLRVQALGGAKNHLVVMPDADLDQAVDALMGAAYGSAGERCMAISVAVAVGNVADKL 306 Query: 348 VEALIPRVKALKVKNGMEDDAEMGPLVTAAHKAKVEGYIQSGVDAGAKLLVDGRGLKVPG 407 +EALIPRVKALK+KNGME DAEMGP+V+A HK K+E YI+ GV AGAKLLVDGRGLKV G Sbjct: 307 IEALIPRVKALKIKNGMEADAEMGPVVSAVHKEKIEAYIEGGVAAGAKLLVDGRGLKVAG 366 Query: 408 HEEGFF-GGTLFDNVTTEMKIYQEEIFGPVLCVVRVPDFASAVQLINAHEYGNGVSLFTA 466 E+GFF GG+LFD VT EMKIYQEEIFGPVLC+VRVPDFA+AV LINAHE+GNGV+LFT+ Sbjct: 367 LEQGFFLGGSLFDQVTPEMKIYQEEIFGPVLCIVRVPDFAAAVNLINAHEFGNGVALFTS 426 Query: 467 DGNTAHEFSRRIQVGMVGINVPIPVPMAWHSFGGWKRSLFGDTHAYGEEGIRFYTRYKSI 526 DGNTA EFSRRI+VGMVGINVPIPVPMAWHSFGGWKRSLFGDTHAYGEEGIRFYTRYKSI Sbjct: 427 DGNTAREFSRRIEVGMVGINVPIPVPMAWHSFGGWKRSLFGDTHAYGEEGIRFYTRYKSI 486 Query: 527 MQRWSATIGKGAEFTMPVAK 546 MQRW TI KGAEFTMPVAK Sbjct: 487 MQRWPQTISKGAEFTMPVAK 506 >ref|YP_001355332.1| methylmalonate-semialdehyde dehydrogenase [Janthinobacterium sp. Marseille] gb|ABR88793.1| methylmalonate-semialdehyde dehydrogenase [Janthinobacterium sp. Marseille] Length = 505 Score = 798 bits (2062), Expect = 0.0, Method: Composition-based stats. Identities = 402/499 (80%), Positives = 456/499 (91%), Gaps = 2/499 (0%) Query: 50 IDHFINGQISRSESGRSEDVFNPATGAATAKVSLASVQEVNAAVAAASAAAPAWAETAPL 109 I H+ING+++ + GR +DVFNPATG A+A+V LAS +V A VA A AAAPAWA+TAPL Sbjct: 7 IKHYINGRLTETAGGRQQDVFNPATGEASAQVVLASDADVQAVVATAKAAAPAWADTAPL 66 Query: 110 KRARVLFKFKELIEQNHDALAKAITLEHGKVFSDAKGEVTRGLEIVEFATGIPQLLKTQF 169 KRAR+LFKFK+LIE++HD LA AIT EHGKVFSDAKGEVTRGLE+VEFA G+PQLLKTQF Sbjct: 67 KRARILFKFKDLIEKHHDDLAAAITREHGKVFSDAKGEVTRGLEVVEFACGVPQLLKTQF 126 Query: 170 TDNIGGGIDNWNLRQPLGVTAGITPFNFPVMVPLWMAPIAIATGNSFVLKPSERDPSPSL 229 TDNIGGGIDNWNLRQPLGVTAGITPFNFP MVP+WMAP+A+ATGN+F+LKPSERDPSPSL Sbjct: 127 TDNIGGGIDNWNLRQPLGVTAGITPFNFPFMVPMWMAPVALATGNTFILKPSERDPSPSL 186 Query: 230 MLAELFKRAGLPDGVFNVVQGDKVAVDALLEHPEVQAVSFVGSTPIAEYIYRK-ATERAG 288 M+AEL ++AGLPDGVFNV+QGDK+AVD LL+HP+V+AVSFVGSTPIAEYIY A + G Sbjct: 187 MVAELLQQAGLPDGVFNVLQGDKLAVDGLLQHPDVKAVSFVGSTPIAEYIYATGAARKGG 246 Query: 289 TFPLRAQALGGAKNHLVVMPDANLEQAVDALIGAAYGSAGERCMAISVAVAVGSVADKLV 348 ++PLR QALGGAKNHLVVMPDANLEQAVDALIGAAYGSAGERCMAISVAVAVG +ADKLV Sbjct: 247 SYPLRVQALGGAKNHLVVMPDANLEQAVDALIGAAYGSAGERCMAISVAVAVGDIADKLV 306 Query: 349 EALIPRVKALKVKNGMEDDAEMGPLVTAAHKAKVEGYIQSGVDAGAKLLVDGRGLKVPGH 408 ALIPRVK+LKVKNGME DAEMGP+V+AAHKAK+EGYI +GV AGAKLLVDGRGLKV GH Sbjct: 307 AALIPRVKSLKVKNGMEADAEMGPVVSAAHKAKIEGYIDAGVKAGAKLLVDGRGLKVAGH 366 Query: 409 EEGFF-GGTLFDNVTTEMKIYQEEIFGPVLCVVRVPDFASAVQLINAHEYGNGVSLFTAD 467 ++GFF GG LFD+VT EM IYQEEIFGPVLCV+RVP+FA+A++LIN HE+GNGVSLFT+D Sbjct: 367 DKGFFLGGCLFDHVTPEMTIYQEEIFGPVLCVLRVPNFAAALELINRHEFGNGVSLFTSD 426 Query: 468 GNTAHEFSRRIQVGMVGINVPIPVPMAWHSFGGWKRSLFGDTHAYGEEGIRFYTRYKSIM 527 GNTA EFSRR++VGMVGINVPIPVPMAWHSFGGWKRS+FGDTHAYGEEGI+FYTRYKSIM Sbjct: 427 GNTAREFSRRVEVGMVGINVPIPVPMAWHSFGGWKRSMFGDTHAYGEEGIKFYTRYKSIM 486 Query: 528 QRWSATIGKGAEFTMPVAK 546 QRW +IGKGAEF MP +K Sbjct: 487 QRWPESIGKGAEFAMPTSK 505 >ref|YP_001101643.1| methylmalonate-semialdehyde dehydrogenase, oxidoreductase protein [Herminiimonas arsenicoxydans] emb|CAL63522.1| methylmalonate-semialdehyde dehydrogenase [acylating] (MMSDH) [Herminiimonas arsenicoxydans] Length = 506 Score = 791 bits (2044), Expect = 0.0, Method: Composition-based stats. Identities = 396/498 (79%), Positives = 448/498 (89%), Gaps = 1/498 (0%) Query: 50 IDHFINGQISRSESGRSEDVFNPATGAATAKVSLASVQEVNAAVAAASAAAPAWAETAPL 109 I+H+ING ++ + G + VFNPATG +A V LAS +V AVAAA AAAPAWAE APL Sbjct: 9 IEHYINGNLTNTVGGGQQPVFNPATGEISANVVLASDADVQTAVAAAKAAAPAWAEMAPL 68 Query: 110 KRARVLFKFKELIEQNHDALAKAITLEHGKVFSDAKGEVTRGLEIVEFATGIPQLLKTQF 169 KRAR+LFKFK+LIE++H+ LA AIT EHGKVFSDAKGEVTRGLE+VEFA G+PQLLKTQF Sbjct: 69 KRARILFKFKDLIERHHNDLAAAITREHGKVFSDAKGEVTRGLEVVEFACGVPQLLKTQF 128 Query: 170 TDNIGGGIDNWNLRQPLGVTAGITPFNFPVMVPLWMAPIAIATGNSFVLKPSERDPSPSL 229 +DNIGGGIDNWNLRQPLGVTAGITPFNFP MVP+WMAP+A+ATGN+F+LKPSERDPSPSL Sbjct: 129 SDNIGGGIDNWNLRQPLGVTAGITPFNFPFMVPMWMAPVALATGNTFILKPSERDPSPSL 188 Query: 230 MLAELFKRAGLPDGVFNVVQGDKVAVDALLEHPEVQAVSFVGSTPIAEYIYRKATERAGT 289 M+AEL +AGLPDGVFNV+QGDK AVD LL+HP+++AVSFVGSTPIAEYIY+ R G+ Sbjct: 189 MVAELLHQAGLPDGVFNVLQGDKRAVDGLLQHPDIKAVSFVGSTPIAEYIYQAGAARKGS 248 Query: 290 FPLRAQALGGAKNHLVVMPDANLEQAVDALIGAAYGSAGERCMAISVAVAVGSVADKLVE 349 +PLR QALGGAKNHLVVMPDANLEQAVDALIGAAYGSAGERCMAISVAVAVGSVADKLV Sbjct: 249 YPLRVQALGGAKNHLVVMPDANLEQAVDALIGAAYGSAGERCMAISVAVAVGSVADKLVA 308 Query: 350 ALIPRVKALKVKNGMEDDAEMGPLVTAAHKAKVEGYIQSGVDAGAKLLVDGRGLKVPGHE 409 ALIPRVK+LKVKNGME DAEMGP+V+AAHKAK+EGYI++G+ +GAKLLVDGRGL V GH Sbjct: 309 ALIPRVKSLKVKNGMESDAEMGPVVSAAHKAKIEGYIEAGIKSGAKLLVDGRGLTVDGHS 368 Query: 410 EGFF-GGTLFDNVTTEMKIYQEEIFGPVLCVVRVPDFASAVQLINAHEYGNGVSLFTADG 468 GFF GG LFDNVT EM IYQEEIFGPVLCVVRVPDF++A+ LINAHE+GNGV+LFT+DG Sbjct: 369 NGFFLGGCLFDNVTPEMTIYQEEIFGPVLCVVRVPDFSAALDLINAHEFGNGVALFTSDG 428 Query: 469 NTAHEFSRRIQVGMVGINVPIPVPMAWHSFGGWKRSLFGDTHAYGEEGIRFYTRYKSIMQ 528 NTA EFSRR+++GMVGINVPIPVPMAWHSFGGWKRS+FGDTHAYGEEGI+FYTRYKSIMQ Sbjct: 429 NTAREFSRRVEIGMVGINVPIPVPMAWHSFGGWKRSMFGDTHAYGEEGIKFYTRYKSIMQ 488 Query: 529 RWSATIGKGAEFTMPVAK 546 RW +I KGAEF MP +K Sbjct: 489 RWPESISKGAEFAMPTSK 506 >ref|YP_004750751.1| methylmalonate-semialdehyde dehydrogenase [Collimonas fungivorans Ter331] gb|AEK59928.1| Methylmalonate-semialdehyde dehydrogenase [Collimonas fungivorans Ter331] Length = 499 Score = 772 bits (1993), Expect = 0.0, Method: Composition-based stats. Identities = 384/503 (76%), Positives = 428/503 (85%), Gaps = 5/503 (0%) Query: 45 MSLPHIDHFINGQISRSESGRSEDVFNPATGAATAKVSLASVQEVNAAVAAASAAAPAWA 104 M++P I+HFI+G + S R DVFNPATGA A+V+LAS QEV+ VA+A AA PAWA Sbjct: 1 MNIPQINHFISGTQATGRSERYSDVFNPATGAVVAQVALASTQEVDKVVASACAAFPAWA 60 Query: 105 ETAPLKRARVLFKFKELIEQNHDALAKAITLEHGKVFSDAKGEVTRGLEIVEFATGIPQL 164 ET+PL+RAR++FKFKEL+EQ+HD LA IT EHGKVFSDAKGEV RG+E+VEFA GIP L Sbjct: 61 ETSPLRRARIMFKFKELLEQHHDQLAALITREHGKVFSDAKGEVVRGIEVVEFACGIPHL 120 Query: 165 LKTQFTDNIGGGIDNWNLRQPLGVTAGITPFNFPVMVPLWMAPIAIATGNSFVLKPSERD 224 LKT TDNIGGGIDNWNLRQPLGV AGITPFNFPVMVP+WM P+AIA GN F+LKPSERD Sbjct: 121 LKTSHTDNIGGGIDNWNLRQPLGVVAGITPFNFPVMVPMWMFPVAIACGNCFILKPSERD 180 Query: 225 PSPSLMLAELFKRAGLPDGVFNVVQGDKVAVDALLEHPEVQAVSFVGSTPIAEYIYRKAT 284 PS SL++A+L K+AGLPDGVFNVVQGDK AVDALL HP+VQA+SFVGSTPIAEYIY + Sbjct: 181 PSASLLIADLLKQAGLPDGVFNVVQGDKTAVDALLAHPDVQALSFVGSTPIAEYIYTEGA 240 Query: 285 ERAGTFPLRAQALGGAKNHLVVMPDANLEQAVDALIGAAYGSAGERCMAISVAVAVGSVA 344 R R QALGGAKNHLVVMPDA+LEQAVDALIGAAYGSAGERCMAISVAVAVG VA Sbjct: 241 RRGK----RVQALGGAKNHLVVMPDADLEQAVDALIGAAYGSAGERCMAISVAVAVGDVA 296 Query: 345 DKLVEALIPRVKALKVKNGMEDDAEMGPLVTAAHKAKVEGYIQSGVDAGAKLLVDGRGLK 404 D+LV+ L R ALK+ NG + D+EMGPLVT HKAKVE Y+ GV+ GAKLLVDGRG+ Sbjct: 297 DRLVQQLAQRAAALKIGNGDQADSEMGPLVTGVHKAKVEAYVAKGVEEGAKLLVDGRGIS 356 Query: 405 VPGHEEGFF-GGTLFDNVTTEMKIYQEEIFGPVLCVVRVPDFASAVQLINAHEYGNGVSL 463 V GHE GFF GGTLFD+VT EM IY+EEIFGPVL VVRVPD ASAV+L+NAHE+GNGVSL Sbjct: 357 VAGHENGFFVGGTLFDHVTPEMTIYKEEIFGPVLSVVRVPDLASAVELVNAHEFGNGVSL 416 Query: 464 FTADGNTAHEFSRRIQVGMVGINVPIPVPMAWHSFGGWKRSLFGDTHAYGEEGIRFYTRY 523 FT+DG A FSR+IQVGMVGINVPIPVPMAWHSFGGWKRSLFGD HAYGEEGIRFYTRY Sbjct: 417 FTSDGGVARAFSRQIQVGMVGINVPIPVPMAWHSFGGWKRSLFGDHHAYGEEGIRFYTRY 476 Query: 524 KSIMQRWSATIGKGAEFTMPVAK 546 KSIMQRW +I KGAEFTMPVAK Sbjct: 477 KSIMQRWPDSIAKGAEFTMPVAK 499