BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0037.0101.p (515 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value emb|CAL60852.2| conserved hypothetical protein; putative EAL and... 368 1e-99 ref|ZP_08275854.1| putative GGDEF domain protein [Oxalobacterace... 298 2e-78 ref|YP_001354036.1| sensory box/GGDEF family protein [Janthinoba... 287 3e-75 ref|YP_001098979.1| GGDEF domain-containing protein [Herminiimon... 281 2e-73 ref|ZP_01311942.1| diguanylate cyclase [Desulfuromonas acetoxida... 225 2e-56 >emb|CAL60852.2| conserved hypothetical protein; putative EAL and GGDEF domains [Herminiimonas arsenicoxydans] Length = 783 Score = 368 bits (945), Expect = 1e-99, Method: Compositional matrix adjust. Identities = 228/520 (43%), Positives = 312/520 (60%), Gaps = 30/520 (5%) Query: 21 GLSACFVLLSSLVLVVIWGITMTHVASEKKLAMESASSESRNMAAIMAANLNDRLSRAGQ 80 GL + L+ +L +IW T V EK L +E++ ++S+N+AAI+A+NLN+ L RA + Sbjct: 21 GLIGGPIFLALTMLAIIWWGTWVRVEHEKALTLENSIADSKNIAAIVASNLNEVLERATR 80 Query: 81 YAMVGSKVLDGDAAAADYLGLLFNGDSAYVRAAVFDDRMRLRYSSAGLPEESEFAQLLER 140 Y+ + +++GD +A L GD AY+R AVFD + L SSA E E QL+ Sbjct: 81 YSQIARSMIEGDPSAMQQLNPTRYGDRAYLRIAVFDHQGNLIQSSANRALEPELLQLVLM 140 Query: 141 AYPQAATGADAPKAGTVLFGKT---DSHNWRMPMLIALQAPKTGARGYLVAILDLGRFLH 197 A A A + ++ G+ D WR+P+LI + G RG+L AI+DLG FL Sbjct: 141 A---KANRFGALQDEQLIVGRPARDDGSAWRVPVLIPFNSSVQG-RGFLAAIIDLGYFLQ 196 Query: 198 DYQQI--GDGYLIAINGGAGTPLVALNDRRLLIGDNSVASVSSSS--------------- 240 Y+ + GD I + G L LN L G + AS S Sbjct: 197 LYKDVNLGDDGRIEVLAHDGYQLAELNGAMLSGGIDFSASEFGKSLEHAADGVIDVKRPG 256 Query: 241 -----VSSLQKLVAYPLSVSVTINPDSVVSDLTQSHYEYVRYAIVISIAVVTLTLILIGI 295 + L+++ YPL V VT + + ++S L H Y+ AI +SIAVV L L+ I Sbjct: 257 MPLEDIGVLRRVRNYPLLVVVTHDQNYLMSRLVDRHQGYLWRAIAVSIAVVFLLCGLLMI 316 Query: 296 SYHRKKLYERLARSEREKICLIEQLEKEKTRAYQLASHDYLTGIPNRMLFSELAGAELSR 355 + +++LY L SE+EK+ LI QLE+EK+RA ASHDYLTG+PNR LF E+A EL+R Sbjct: 317 ASRQRRLYNVLTASEQEKLNLISQLEQEKSRALLQASHDYLTGVPNRRLFYEMAATELAR 376 Query: 356 AKRSPNLYALFFIDLDGFKPINDTLGHAVGDLLLKAVAQRLCTNLREYDLVARLGGDEFV 415 AKRS LYALFF+DLD FK INDTLGHAVGDLLL+ VA+RL +LREYDL+ARLGGDEFV Sbjct: 377 AKRSRKLYALFFLDLDKFKLINDTLGHAVGDLLLQGVARRLRESLREYDLLARLGGDEFV 436 Query: 416 VLLSDIKYQSQIADIADKLIKAVGAPYLNLGGHEVGTSLSIGIALYPDDGHTVDELLSKA 475 +L+S++ +S IA +A KL+ V P+L+LGG+++ S SIGIALYP DG V+ LL A Sbjct: 437 ILVSEMASESDIARVAAKLVDVVRDPFLDLGGNDIDVSPSIGIALYPRDGQDVETLLMHA 496 Query: 476 DAAMYAAKKDGKGAYRFHDSSVHSGLSGRLPSTATRYLSA 515 D AMY+AK G YRF D+S+++ S R +R+ A Sbjct: 497 DLAMYSAKSAGAATYRFFDTSLNAS-SARETELLSRFKRA 535 >ref|ZP_08275854.1| putative GGDEF domain protein [Oxalobacteraceae bacterium IMCC9480] gb|EGF30674.1| putative GGDEF domain protein [Oxalobacteraceae bacterium IMCC9480] Length = 781 Score = 298 bits (762), Expect = 2e-78, Method: Compositional matrix adjust. Identities = 205/517 (39%), Positives = 292/517 (56%), Gaps = 47/517 (9%) Query: 16 IQDGWGLSACFVLLSSLVLVVIWGITMTHVASEKKLAMESASSESRNMAAIMAANLNDRL 75 +++G GL A L++ L+L VIW +T + +A E+ A++ + S SRN+A+I+AANL++ Sbjct: 16 LRNGKGLVAGIALMALLLLAVIWFLTSSRIAGERLEALDKSVSSSRNVASIVAANLDEVF 75 Query: 76 SRAGQYAMVGSKVLDGDAAAADYLGLLFNGDSAYVRAAVFDDRMRLRYSS---AGLPEES 132 R YA + + L+ L GD+A++R A+F +L YSS A PE Sbjct: 76 GRTAIYARLSTAYLEQPGEHPASFNALSIGDTAFLRMAIFGADGKLAYSSSRRAVEPELQ 135 Query: 133 EFAQ--LLERAYPQAA---TGADAPKAGTVLFGKTDSHNWRMPMLIALQAPKTGAR--GY 185 FA+ L A P TGAD P A WR+P+ L +G R G Sbjct: 136 LFARTTLFAEAPPPIVIGHTGADDPHAA-----------WRIPVAAPLL---SGQRRIGV 181 Query: 186 LVAILDLGRFLHDYQQ--IGDGYLIAINGGAGTPLVALNDRRLLIGDN------------ 231 +DLG L Y++ G I + G LV L + L G N Sbjct: 182 FAGYIDLGYVLALYKEASFGTRSRIEVIDTRGIQLVELYEGTLSAGRNLERAGYARFTSR 241 Query: 232 ---------SVASVSSSSVSSLQKLVAYPLSVSVTINPDSVVSDLTQSHYEYVRYAIVIS 282 + S +S+ ++L +PL V+VT + +V+ +L H Y A ++S Sbjct: 242 TEPAGAIDMARPGDSGASIGVYRRLDHFPLVVTVTRDRSAVLEELQLRHRTYRIRATLLS 301 Query: 283 IAVVTLTLILIGISYHRKKLYERLARSEREKICLIEQLEKEKTRAYQLASHDYLTGIPNR 342 + ++ T L+ ++ +++L L SE LI+QLE EKTRA+QLAS D+LTGIPNR Sbjct: 302 LLILLATAGLMVLAQRQRRLNLGLTDSESRNQTLIQQLETEKTRAFQLASLDFLTGIPNR 361 Query: 343 MLFSELAGAELSRAKRSPNLYALFFIDLDGFKPINDTLGHAVGDLLLKAVAQRLCTNLRE 402 M F ELA EL RA+RS L A+FF+DLD FK INDT GH VGDLLL+ VA RL +LR Sbjct: 362 MKFYELAEIELVRARRSRKLTAVFFLDLDKFKAINDTHGHGVGDLLLQQVASRLRHSLRG 421 Query: 403 YDLVARLGGDEFVVLLSDIKYQSQIADIADKLIKAVGAPYLNLGGHEVGTSLSIGIALYP 462 YDL ARLGGDEF VL+S + +A +A+KL+ ++ A YL+L GH++ + SIGIALYP Sbjct: 422 YDLAARLGGDEFAVLVSGLDSDDAVATVANKLVASLSATYLDLDGHDLDVTPSIGIALYP 481 Query: 463 DDGHTVDELLSKADAAMYAAKKDGKGAYRFHDSSVHS 499 DG +D LLS+AD AMY AK+ G+G YRF+++S+++ Sbjct: 482 GDGEEIDTLLSRADRAMYLAKQSGRGCYRFYEASLNA 518 >ref|YP_001354036.1| sensory box/GGDEF family protein [Janthinobacterium sp. Marseille] gb|ABR89516.1| sensory box/GGDEF family protein [Janthinobacterium sp. Marseille] Length = 641 Score = 287 bits (735), Expect = 3e-75, Method: Compositional matrix adjust. Identities = 179/377 (47%), Positives = 242/377 (64%), Gaps = 25/377 (6%) Query: 162 TDSHNWRMPMLIALQAPKTGARGYLVAILDLGRFLHDYQQI--GDGYLIAI--------- 210 +D+ WR+P++I A G+L A++DLG FL Y+ I GDG I I Sbjct: 19 SDNSAWRVPIVIPF-ATADRQHGFLAAVIDLGYFLRLYKDIHLGDGGRIEILTRDAYQLA 77 Query: 211 --NGG---AGTPLVALNDRRLLIGDNSVASVSSS-------SVSSLQKLVAYPLSVSVTI 258 NG AG + + L G + + ++ ++ + L +YP +V VT Sbjct: 78 ELNGAGLSAGVDYAGSDYAKFLHGQEAEGVIEATRPGAAEQEIAVFRMLGSYPFTVVVTR 137 Query: 259 NPDSVVSDLTQSHYEYVRYAIVISIAVVTLTLILIGISYHRKKLYERLARSEREKICLIE 318 + V++ LT H +Y++ AI++S+AVV L L+ I+Y +++LY LA SE+EK LI Sbjct: 138 DQSYVMARLTARHRDYLQRAIIVSVAVVLLMFGLLVIAYRQRRLYNVLAASEQEKRSLIG 197 Query: 319 QLEKEKTRAYQLASHDYLTGIPNRMLFSELAGAELSRAKRSPNLYALFFIDLDGFKPIND 378 QLE+EK RA ASHDYLTGIPNRMLF ELA AEL+RA+RS LY +FF+DLD FK IND Sbjct: 198 QLEQEKGRALLQASHDYLTGIPNRMLFYELAAAELARARRSRKLYGMFFLDLDKFKLIND 257 Query: 379 TLGHAVGDLLLKAVAQRLCTNLREYDLVARLGGDEFVVLLSDIKYQSQIADIADKLIKAV 438 TLGHAVGDLLL+ VA+RL +LREYDL+ARLGGDEFV+L+S++ ++ IA +A KL++ V Sbjct: 258 TLGHAVGDLLLQGVARRLRESLREYDLLARLGGDEFVMLISEMTSENDIAKVAAKLVEVV 317 Query: 439 GAPYLNLGGHEVGTSLSIGIALYPDDGHTVDELLSKADAAMYAAKKDGKGAYRFHDSSVH 498 P+ +L GH++ S SIGIALYP DG V+ LL+ ADAAMY AK G G YRF DSS++ Sbjct: 318 REPFPDLDGHDIEISPSIGIALYPRDGQNVETLLTHADAAMYHAKAAGAGTYRFFDSSLN 377 Query: 499 SGLSGRLPSTATRYLSA 515 + S R TR+ A Sbjct: 378 AS-SARDVELLTRFKRA 393 >ref|YP_001098979.1| GGDEF domain-containing protein [Herminiimonas arsenicoxydans] Length = 599 Score = 281 bits (720), Expect = 2e-73, Method: Compositional matrix adjust. Identities = 168/352 (47%), Positives = 221/352 (62%), Gaps = 23/352 (6%) Query: 186 LVAILDLGRFLHDYQQI--GDGYLIAINGGAGTPLVALNDRRLLIGDNSVASVSSSS--- 240 + AI+DLG FL Y+ + GD I + G L LN L G + AS S Sbjct: 1 MAAIIDLGYFLQLYKDVNLGDDGRIEVLAHDGYQLAELNGAMLSGGIDFSASEFGKSLEH 60 Query: 241 -----------------VSSLQKLVAYPLSVSVTINPDSVVSDLTQSHYEYVRYAIVISI 283 + L+++ YPL V VT + + ++S L H Y+ AI +SI Sbjct: 61 AADGVIDVKRPGMPLEDIGVLRRVRNYPLLVVVTHDQNYLMSRLVDRHQGYLWRAIAVSI 120 Query: 284 AVVTLTLILIGISYHRKKLYERLARSEREKICLIEQLEKEKTRAYQLASHDYLTGIPNRM 343 AVV L L+ I+ +++LY L SE+EK+ LI QLE+EK+RA ASHDYLTG+PNR Sbjct: 121 AVVFLLCGLLMIASRQRRLYNVLTASEQEKLNLISQLEQEKSRALLQASHDYLTGVPNRR 180 Query: 344 LFSELAGAELSRAKRSPNLYALFFIDLDGFKPINDTLGHAVGDLLLKAVAQRLCTNLREY 403 LF E+A EL+RAKRS LYALFF+DLD FK INDTLGHAVGDLLL+ VA+RL +LREY Sbjct: 181 LFYEMAATELARAKRSRKLYALFFLDLDKFKLINDTLGHAVGDLLLQGVARRLRESLREY 240 Query: 404 DLVARLGGDEFVVLLSDIKYQSQIADIADKLIKAVGAPYLNLGGHEVGTSLSIGIALYPD 463 DL+ARLGGDEFV+L+S++ +S IA +A KL+ V P+L+LGG+++ S SIGIALYP Sbjct: 241 DLLARLGGDEFVILVSEMASESDIARVAAKLVDVVRDPFLDLGGNDIDVSPSIGIALYPR 300 Query: 464 DGHTVDELLSKADAAMYAAKKDGKGAYRFHDSSVHSGLSGRLPSTATRYLSA 515 DG V+ LL AD AMY+AK G YRF D+S+++ S R +R+ A Sbjct: 301 DGQDVETLLMHADLAMYSAKSAGAATYRFFDTSLNAS-SARETELLSRFKRA 351 >ref|ZP_01311942.1| diguanylate cyclase [Desulfuromonas acetoxidans DSM 684] gb|EAT16351.1| diguanylate cyclase [Desulfuromonas acetoxidans DSM 684] Length = 554 Score = 225 bits (573), Expect = 2e-56, Method: Compositional matrix adjust. Identities = 165/510 (32%), Positives = 249/510 (48%), Gaps = 47/510 (9%) Query: 20 WGLSACFV-----LLSSLVLVVIWGITMTHVASEKKLAMESASSESRNMAAIMAANLNDR 74 WG F+ + +L+ W +T+ + S ++ ++ ++E N+ +I++ NL Sbjct: 34 WGRGCSFLPVAVGVFGLCLLLAAWILTLNQLQSNRRSLLDRVTTEQHNLVSIISKNLTQA 93 Query: 75 LSRAGQYAMVGSKVLD-GDAAAADYLGLLFNGDSAYVRAAVFDDRMRLRYSSAGLPEESE 133 + + LD D A +++ L +G + R V Y S+ SE Sbjct: 94 IDEHRPLKTIVRNALDEQDTAELNHIPELLSGQHFFNRMLVCSRNGTPLYQSSPGTNYSE 153 Query: 134 FAQLLERAYPQAATGADAPKAGTVLFGKTDSHNWRMPMLIALQAPKTGARGYLVAIL--D 191 LL +P D P + D+ W++P++ + T G + IL D Sbjct: 154 QQNLLATFFP-VHQDTDTPFIFNAQLLRPDA-PWQIPLVFRI---ATNRFGSITMILEAD 208 Query: 192 LGRFLHDYQ--QIGDGYLIAINGGAGTPLVALNDRRLLI----------------GDNSV 233 LG L+ YQ IG +I I G PLV + L++ G Sbjct: 209 LGYLLNLYQDVMIGHSGIIRIQTLTGQPLVHIEQGALVVEPATTPNIYWQSNRQFGQTKT 268 Query: 234 ASVSSSS---VSSLQKLVAYPLSVSVTINPDSVVSDLTQSHYEYVRYAIVISIAVVTLTL 290 AS S ++S + L AYPL++SV+ D ++ Y + R ++ ++VVTL L Sbjct: 269 ASYQDHSHLVLTSYRHLSAYPLTISVSQYQDEILQK-----YAHWRRQQLMILSVVTL-L 322 Query: 291 ILIGISY-----HRKKLY-ERLARSEREKICLIEQLEKEKTRAYQLASHDYLTGIPNRML 344 L+G S+ H+K+ Y + L + ++ LI QLE E +A AS D LT + NR L Sbjct: 323 SLVGFSWLVWVAHQKQHYLQALLAANQQNAQLINQLEHEHKQAVDAASRDPLTNLYNRRL 382 Query: 345 FSELAGAELSRAKRSPNLYALFFIDLDGFKPINDTLGHAVGDLLLKAVAQRLCTNLREYD 404 F ELA +L +KR L A+ F+DLD FK INDT GH +GDLLLK VA RL LRE D Sbjct: 383 FIELAQKQLLYSKRKELLCAVLFLDLDRFKEINDTYGHHIGDLLLKKVADRLRDTLREAD 442 Query: 405 LVARLGGDEFVVLLSDIKYQSQIADIADKLIKAVGAPYLNLGGHEVGTSLSIGIALYPDD 464 ++AR GGDEFV+LL I I +KL+ + PY NL G + T+ SIG+A++P Sbjct: 443 IIARYGGDEFVILLDGITRDDHTFQITEKLVHTLSRPYTNLDGLTIHTTPSIGVAMFPKH 502 Query: 465 GHTVDELLSKADAAMYAAKKDGKGAYR-FH 493 V LL +AD AMY +K++G+ + FH Sbjct: 503 AEDVQTLLLQADVAMYWSKENGRAQWTLFH 532