BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0037.0035.p (453 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|ZP_08274871.1| transmembrane protein drug efflux protein [Ox... 751 0.0 ref|YP_004753094.1| acriflavin resistance protein [Collimonas fu... 731 0.0 emb|CBJ37857.1| putative multidrug efflux transporter AcrB trans... 632 e-179 ref|YP_002981519.1| acriflavin resistance protein [Ralstonia pic... 628 e-178 gb|AEG69038.1| cobalt-zinc-cadmium resistance protein czca (cati... 627 e-178 >ref|ZP_08274871.1| transmembrane protein drug efflux protein [Oxalobacteraceae bacterium IMCC9480] gb|EGF31659.1| transmembrane protein drug efflux protein [Oxalobacteraceae bacterium IMCC9480] Length = 1029 Score = 751 bits (1939), Expect = 0.0, Method: Compositional matrix adjust. Identities = 368/450 (81%), Positives = 400/450 (88%) Query: 1 VLVTPGDNLQVRVSGAFHSPKELEEMQLRANGTTFRLGDFAVVKREYVDPPVTKMRFNGK 60 VLVT DNLQVRVSGA + K+L+++ LRANGT+F+LGDFA V+REY DPP KMRFNGK Sbjct: 223 VLVTQTDNLQVRVSGALMTVKDLQDLDLRANGTSFKLGDFATVRREYRDPPQDKMRFNGK 282 Query: 61 EAIGLGVSMEKGGDIIALGRNLDRMSDELRTKLPVGIELERVSDQPKIVADSVGEFIHTL 120 E IGLG+SMEKGG+II LG++LD ++ KLPVG+EL RV+DQPK V SV EF+HTL Sbjct: 283 EVIGLGISMEKGGNIIELGKSLDSTLATIKAKLPVGVELSRVADQPKAVIASVSEFLHTL 342 Query: 121 VEAVLIVLAVSFIALGLHTRPLRIDVRPGLVVALTIPLVLAVTFLFMRIFDIDLHKISLG 180 VEAVLIVLAVSF+ALGLHT+P R+D+RPGLVV LTIPLVLA+TFLFMRI DIDLHKISLG Sbjct: 343 VEAVLIVLAVSFLALGLHTKPFRLDIRPGLVVGLTIPLVLAITFLFMRILDIDLHKISLG 402 Query: 181 ALIIALGLLVDDAIIAVEMMVRKMEEGLSRFDAATFAYTSTAIPMLTGTLITAAGFLPIG 240 ALIIALGLLVDDAIIAVEMMVRKMEEGLSRFDAATFAYTSTA+PMLTGTLITAAGFLPIG Sbjct: 403 ALIIALGLLVDDAIIAVEMMVRKMEEGLSRFDAATFAYTSTAMPMLTGTLITAAGFLPIG 462 Query: 241 LAKSAAGEYTFSMFSVNALALLISWLVAVVFTPYIGVLLLKVKPAANADGHHELFDTPFY 300 LAKSAAGEYTFSMFSVNALAL+ISWLVAV+FTPY+G LLLKVKPAA AD HHELF+TP Y Sbjct: 463 LAKSAAGEYTFSMFSVNALALIISWLVAVIFTPYLGYLLLKVKPAAGADAHHELFNTPMY 522 Query: 301 TRFRKLVTWCVEWRKTTILLTLTAFMLGLLGFRFIEQQFFPDSSRPELMIELWLPEGSAF 360 RFRK V WCVEWRKTTILLTL AF LG+ GF+FIEQQFFPDSSR ELM+ELWLPEGSAF Sbjct: 523 NRFRKTVNWCVEWRKTTILLTLAAFGLGVFGFKFIEQQFFPDSSRTELMVELWLPEGSAF 582 Query: 361 KATEAQAKKFEAFIRKQDGVESVTSYVGTGSPRFYLPLDQIFPQTNVSQIVVLPKDLKTR 420 KATEAQAKKFEAFI+KQDGVESVTSYVGTGSPRFYLPLDQIFPQTNVSQIVVL KDLK R Sbjct: 583 KATEAQAKKFEAFIQKQDGVESVTSYVGTGSPRFYLPLDQIFPQTNVSQIVVLAKDLKAR 642 Query: 421 ESLRLKIVDAFKNDFPGVRGRXDAFKNDFP 450 E+LRLKIV FK DFP VRGR N P Sbjct: 643 EALRLKIVAIFKTDFPEVRGRVKLLPNGPP 672 >ref|YP_004753094.1| acriflavin resistance protein [Collimonas fungivorans Ter331] gb|AEK62271.1| acriflavin resistance protein [Collimonas fungivorans Ter331] Length = 1040 Score = 731 bits (1887), Expect = 0.0, Method: Compositional matrix adjust. Identities = 355/441 (80%), Positives = 399/441 (90%) Query: 1 VLVTPGDNLQVRVSGAFHSPKELEEMQLRANGTTFRLGDFAVVKREYVDPPVTKMRFNGK 60 VL T DNLQ+RVSGA SPK+LE +QLRAN TTFRLGDFAVVKREY DPP TKMRFNGK Sbjct: 227 VLATATDNLQIRVSGALASPKDLENLQLRANNTTFRLGDFAVVKREYQDPPQTKMRFNGK 286 Query: 61 EAIGLGVSMEKGGDIIALGRNLDRMSDELRTKLPVGIELERVSDQPKIVADSVGEFIHTL 120 E IGLGVSM KGGDII+LG++++RM+ +++ KLPVGI+LERVS+QPKIVA+SV EF+ TL Sbjct: 287 EVIGLGVSMAKGGDIISLGKDMERMTAQIKAKLPVGIDLERVSNQPKIVAESVNEFLKTL 346 Query: 121 VEAVLIVLAVSFIALGLHTRPLRIDVRPGLVVALTIPLVLAVTFLFMRIFDIDLHKISLG 180 +EAVLIVLAVSF++LG HT+P RIDVRPGLVVALTIPLVLAVTFLFM IF IDLHKISLG Sbjct: 347 MEAVLIVLAVSFLSLGFHTKPFRIDVRPGLVVALTIPLVLAVTFLFMSIFSIDLHKISLG 406 Query: 181 ALIIALGLLVDDAIIAVEMMVRKMEEGLSRFDAATFAYTSTAIPMLTGTLITAAGFLPIG 240 ALIIALGLLVDDAIIAVEMMVRKMEEGLSR +AATFAYTSTA+PMLTGTLITAAGFLPIG Sbjct: 407 ALIIALGLLVDDAIIAVEMMVRKMEEGLSRLEAATFAYTSTAMPMLTGTLITAAGFLPIG 466 Query: 241 LAKSAAGEYTFSMFSVNALALLISWLVAVVFTPYIGVLLLKVKPAANADGHHELFDTPFY 300 LAKSAAGEYTFSMFSVNALALLISWLVAV+FTPYIG LLLKVKPAA ADGHHELF+TPFY Sbjct: 467 LAKSAAGEYTFSMFSVNALALLISWLVAVLFTPYIGFLLLKVKPAAGADGHHELFNTPFY 526 Query: 301 TRFRKLVTWCVEWRKTTILLTLTAFMLGLLGFRFIEQQFFPDSSRPELMIELWLPEGSAF 360 TR R+ V WCVEWRKTTI LTL F LG+ GF+FIE+QFFPDSSRPELMIELWLPEGS+F Sbjct: 527 TRVRRTVNWCVEWRKTTIALTLMVFALGVFGFKFIEEQFFPDSSRPELMIELWLPEGSSF 586 Query: 361 KATEAQAKKFEAFIRKQDGVESVTSYVGTGSPRFYLPLDQIFPQTNVSQIVVLPKDLKTR 420 ATEA+AKKFEA+I +ES+T+YVG+GSPRFYLPLDQI PQTNV+Q+V+L KDL +R Sbjct: 587 AATEAEAKKFEAYIHAAPELESMTTYVGSGSPRFYLPLDQILPQTNVAQLVLLTKDLASR 646 Query: 421 ESLRLKIVDAFKNDFPGVRGR 441 ++LRL+I +AFK+ FP VRGR Sbjct: 647 DALRLRITEAFKHGFPEVRGR 667 >emb|CBJ37857.1| putative multidrug efflux transporter AcrB transmembrane domain [Ralstonia solanacearum CMR15] Length = 1039 Score = 632 bits (1631), Expect = e-179, Method: Compositional matrix adjust. Identities = 305/453 (67%), Positives = 367/453 (81%), Gaps = 3/453 (0%) Query: 1 VLVTPGDNLQVRVSGAFHSPKELEEMQLRANGTT--FRLGDFAVVKREYVDPPVTKMRFN 58 VLVTP DN+Q+R+SG F ++LE + LR G T RLGD A V+ Y+DPP KMRFN Sbjct: 224 VLVTPTDNVQIRLSGQFSDIRDLENLTLRGPGGTSNIRLGDIATVRHGYIDPPRAKMRFN 283 Query: 59 GKEAIGLGVSMEKGGDIIALGRNLDRMSDELRTKLPVGIELERVSDQPKIVADSVGEFIH 118 GKE IGLG+SM KGGDII LG++L + +R KLPVGIE+++V DQP+ V SVGEF+H Sbjct: 284 GKEVIGLGISMAKGGDIIQLGKDLRATVERIRAKLPVGIEMQQVQDQPQSVQHSVGEFVH 343 Query: 119 TLVEAVLIVLAVSFIALGLHTRP-LRIDVRPGLVVALTIPLVLAVTFLFMRIFDIDLHKI 177 L+EAV+IVLAVSF++LGLHT+P LRIDV PGLVV LTIPLVLAVTFLFM IFDI LHKI Sbjct: 344 VLIEAVVIVLAVSFLSLGLHTKPRLRIDVWPGLVVGLTIPLVLAVTFLFMNIFDIGLHKI 403 Query: 178 SLGALIIALGLLVDDAIIAVEMMVRKMEEGLSRFDAATFAYTSTAIPMLTGTLITAAGFL 237 SLGALIIALGLLVDDAIIAVEMMVRK+EEG S+ +AATFAYTSTA+PMLTGTLITA GFL Sbjct: 404 SLGALIIALGLLVDDAIIAVEMMVRKLEEGFSKMEAATFAYTSTAMPMLTGTLITATGFL 463 Query: 238 PIGLAKSAAGEYTFSMFSVNALALLISWLVAVVFTPYIGVLLLKVKPAANADGHHELFDT 297 P+GLA+S GEYTF +F+V ALAL++SW+ AVVF PY+G LLL K A GHHELFDT Sbjct: 464 PVGLARSTVGEYTFGIFAVTALALVLSWVAAVVFVPYLGYLLLHTKSHAGDGGHHELFDT 523 Query: 298 PFYTRFRKLVTWCVEWRKTTILLTLTAFMLGLLGFRFIEQQFFPDSSRPELMIELWLPEG 357 PFY RFR V WCVE+RKT I++TL AF+LG+ GF+++E+QFFPDSSRPELM+ELWLPEG Sbjct: 524 PFYNRFRGWVNWCVEYRKTVIVITLAAFVLGVFGFKYVEKQFFPDSSRPELMVELWLPEG 583 Query: 358 SAFKATEAQAKKFEAFIRKQDGVESVTSYVGTGSPRFYLPLDQIFPQTNVSQIVVLPKDL 417 ++F TEA+AK+FEA IR+Q VESVT +VG+G+PRFYLPLDQI PQTNV+Q +V+P L Sbjct: 584 ASFSQTEAEAKRFEALIRQQKSVESVTFFVGSGAPRFYLPLDQILPQTNVAQAIVMPTSL 643 Query: 418 KTRESLRLKIVDAFKNDFPGVRGRXDAFKNDFP 450 +TRE +R +I+ K+ FP +RGR N P Sbjct: 644 ETREDVRQEIIGLLKSQFPQLRGRVKLLPNGPP 676 >ref|YP_002981519.1| acriflavin resistance protein [Ralstonia pickettii 12D] ref|ZP_07677362.1| RND efflux transporter, hydrophobe/amphiphile efflux-1 (HAE1) family [Ralstonia sp. 5_7_47FAA] gb|ACS62847.1| acriflavin resistance protein [Ralstonia pickettii 12D] gb|EFP64290.1| RND efflux transporter, hydrophobe/amphiphile efflux-1 (HAE1) family [Ralstonia sp. 5_7_47FAA] Length = 1039 Score = 628 bits (1619), Expect = e-178, Method: Compositional matrix adjust. Identities = 301/453 (66%), Positives = 363/453 (80%), Gaps = 3/453 (0%) Query: 1 VLVTPGDNLQVRVSGAFHSPKELEEMQLRANG--TTFRLGDFAVVKREYVDPPVTKMRFN 58 VLVTP DN+Q+R+SG F ++LE + LR G T RLGD A VK YVDPP KMRFN Sbjct: 224 VLVTPTDNVQIRLSGQFSDIRDLENLTLRGPGGTTNIRLGDIATVKHGYVDPPHAKMRFN 283 Query: 59 GKEAIGLGVSMEKGGDIIALGRNLDRMSDELRTKLPVGIELERVSDQPKIVADSVGEFIH 118 GKE IGLG+SM KGGDII LG++L D++R KLP+GIE+++V +QPK V SVGEF+H Sbjct: 284 GKEVIGLGISMTKGGDIIQLGKDLRATVDKIRAKLPMGIEMQQVQNQPKSVQSSVGEFVH 343 Query: 119 TLVEAVLIVLAVSFIALGLHTRP-LRIDVRPGLVVALTIPLVLAVTFLFMRIFDIDLHKI 177 L+EAV+IVL VSF++LGLHT+P LRIDV PGLVV LTIPLVLAVTFLFM IFDI LHKI Sbjct: 344 VLIEAVVIVLGVSFLSLGLHTKPKLRIDVWPGLVVGLTIPLVLAVTFLFMNIFDIGLHKI 403 Query: 178 SLGALIIALGLLVDDAIIAVEMMVRKMEEGLSRFDAATFAYTSTAIPMLTGTLITAAGFL 237 SLGALIIALGLLVDDAIIAVEMMVRK+EEG S+ +AATFAYTSTA+PMLTGTLITA GFL Sbjct: 404 SLGALIIALGLLVDDAIIAVEMMVRKLEEGFSKMEAATFAYTSTAMPMLTGTLITATGFL 463 Query: 238 PIGLAKSAAGEYTFSMFSVNALALLISWLVAVVFTPYIGVLLLKVKPAANADGHHELFDT 297 P+GLA+S GEYTF +F+V ALAL++SW AVVF PY+G LLL+ K GHHELFDT Sbjct: 464 PVGLARSTVGEYTFGIFAVTALALVLSWFAAVVFVPYLGFLLLRTKSHVEGGGHHELFDT 523 Query: 298 PFYTRFRKLVTWCVEWRKTTILLTLTAFMLGLLGFRFIEQQFFPDSSRPELMIELWLPEG 357 PFY RFR V WCVE+RKT I++TL AF LG+ GF+++E+QFFPDSSRPELM+ELWLPEG Sbjct: 524 PFYNRFRGWVNWCVEYRKTVIVITLVAFGLGVFGFKYVEKQFFPDSSRPELMVELWLPEG 583 Query: 358 SAFKATEAQAKKFEAFIRKQDGVESVTSYVGTGSPRFYLPLDQIFPQTNVSQIVVLPKDL 417 S+F TEA+AK+FEA +RK+ V+SVT ++G+G+PRFYLPLDQI PQTNV+Q +V+P L Sbjct: 584 SSFNQTEAEAKRFEALMRKEQNVDSVTLFIGSGAPRFYLPLDQILPQTNVAQAIVMPTSL 643 Query: 418 KTRESLRLKIVDAFKNDFPGVRGRXDAFKNDFP 450 + RE +R ++ K+ FP +RGR N P Sbjct: 644 EAREGVRQHVIGLLKSQFPHLRGRVKLLPNGPP 676 >gb|AEG69038.1| cobalt-zinc-cadmium resistance protein czca (cation efflux system protein czca) [Ralstonia solanacearum Po82] Length = 1039 Score = 627 bits (1618), Expect = e-178, Method: Compositional matrix adjust. Identities = 301/453 (66%), Positives = 364/453 (80%), Gaps = 3/453 (0%) Query: 1 VLVTPGDNLQVRVSGAFHSPKELEEMQLRANG--TTFRLGDFAVVKREYVDPPVTKMRFN 58 VLVTP DN+Q+R+SG F ++LE + LR G T RLGD A V+ Y+DPP KMRFN Sbjct: 224 VLVTPTDNVQIRLSGQFSDIRDLENLTLRGPGGTTNIRLGDIATVRHGYIDPPHAKMRFN 283 Query: 59 GKEAIGLGVSMEKGGDIIALGRNLDRMSDELRTKLPVGIELERVSDQPKIVADSVGEFIH 118 GKE IGLG+SM KGGDII LG++L + +RTKLPVGIE+ +V DQP+ V SVGEF+H Sbjct: 284 GKEVIGLGISMAKGGDIIQLGKDLRATVEHIRTKLPVGIEMAQVQDQPQSVQHSVGEFVH 343 Query: 119 TLVEAVLIVLAVSFIALGLHTRP-LRIDVRPGLVVALTIPLVLAVTFLFMRIFDIDLHKI 177 L+EAV+IVL VSF++LGLHT+P LRIDV PGLVV LTIPLVLAVTFLFM IFDI LHKI Sbjct: 344 VLIEAVVIVLGVSFLSLGLHTKPRLRIDVWPGLVVGLTIPLVLAVTFLFMNIFDIGLHKI 403 Query: 178 SLGALIIALGLLVDDAIIAVEMMVRKMEEGLSRFDAATFAYTSTAIPMLTGTLITAAGFL 237 SLGALIIALGLLVDDAIIAVEMMVRK+EEG S+ +AATFAYTSTA+PMLTGTLITA GFL Sbjct: 404 SLGALIIALGLLVDDAIIAVEMMVRKLEEGFSKMEAATFAYTSTAMPMLTGTLITATGFL 463 Query: 238 PIGLAKSAAGEYTFSMFSVNALALLISWLVAVVFTPYIGVLLLKVKPAANADGHHELFDT 297 P+GLA+S GEYTF +F+V ALAL++SW+ AVVF PY+G LLL K A GHHELFDT Sbjct: 464 PVGLARSTVGEYTFGIFAVTALALVLSWVAAVVFVPYLGYLLLHTKSHAGDGGHHELFDT 523 Query: 298 PFYTRFRKLVTWCVEWRKTTILLTLTAFMLGLLGFRFIEQQFFPDSSRPELMIELWLPEG 357 PFY RFR V WCVE+RKT I++TL AF+LG+ GF+++E+QFFPDSSRPELM+ELWLPEG Sbjct: 524 PFYNRFRGWVNWCVEYRKTVIVITLVAFVLGVFGFKYVEKQFFPDSSRPELMVELWLPEG 583 Query: 358 SAFKATEAQAKKFEAFIRKQDGVESVTSYVGTGSPRFYLPLDQIFPQTNVSQIVVLPKDL 417 ++F TEA+AK+FEA +R+Q VESV ++G+G+PRFYLPLDQI PQTNV+Q +V+P L Sbjct: 584 ASFSQTEAEAKRFEALMRQQKNVESVAFFIGSGAPRFYLPLDQILPQTNVAQAIVMPTSL 643 Query: 418 KTRESLRLKIVDAFKNDFPGVRGRXDAFKNDFP 450 +TRE +R I+ ++ FP +RGR N P Sbjct: 644 ETREGVRQAIIGLLQSQFPHLRGRVKLLPNGPP 676