BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0037.0005.p (326 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_001099277.1| putative cobalamin biosynthesis protein [Her... 387 e-105 ref|YP_001352788.1| cobalamin biosynthesis protein CobD [Janthin... 386 e-105 ref|YP_003776047.1| cobalamin biosynthesis CobD/CbiB [Herbaspiri... 360 1e-97 ref|ZP_03270781.1| cobalamin biosynthesis protein CobD [Burkhold... 330 2e-88 ref|YP_003604329.1| cobalamin biosynthesis protein CobD [Burkhol... 328 9e-88 >ref|YP_001099277.1| putative cobalamin biosynthesis protein [Herminiimonas arsenicoxydans] emb|CAL61150.1| putative cobalamin biosynthesis protein CbiB [Herminiimonas arsenicoxydans] Length = 304 Score = 387 bits (993), Expect = e-105, Method: Compositional matrix adjust. Identities = 202/298 (67%), Positives = 225/298 (75%) Query: 17 MAAGVALDWLLGETRRWHPLVGFGRYVQCLERRLNRQPGSYARGVFAWLLAVLPPVALAC 76 M GV LD LGE RWHPLVGFG +E++LN RG AW+L VLP V +A Sbjct: 1 MMLGVLLDMRLGEATRWHPLVGFGNLAIRIEKKLNTGGSRIVRGAVAWMLIVLPLVLVAW 60 Query: 77 AATILLARQSLWLAAAWHVLLLYFCIGLRSLRDHVMPIAAALKDGDLAAARALTGRIVSR 136 T LA+ L LA H LLLYF +GLRSLRDH +PIA AL DGDL+ AR LT RIVSR Sbjct: 61 LLTFWLAQFDLLLAFGVHALLLYFGLGLRSLRDHTLPIAHALMDGDLSQARLLTARIVSR 120 Query: 137 DTTQSQETDLAKAAVESLLENGNDAVFGTLFWFAVAGGPGALLFRLANTLDAMWGYRTSR 196 DTTQ+QE DLAKA VESLLENGNDAVFGTLFWF +AGGPG +LFR ANTLDAMWGYRT R Sbjct: 121 DTTQAQEADLAKAGVESLLENGNDAVFGTLFWFVLAGGPGVVLFRFANTLDAMWGYRTQR 180 Query: 197 FLAFGCAAARLDDALNWIPARLTALSYAALGNWRQARTCWHEQAPAWSSPNAGPVMSSGA 256 F FG AAR+DD LN+IPARLTALSYA LGN +QA CW QAPAWSSPNAGPVMS+GA Sbjct: 181 FNEFGRVAARIDDVLNFIPARLTALSYAVLGNAKQAWQCWRVQAPAWSSPNAGPVMSAGA 240 Query: 257 GALGLALGGAAIYDGEVEQRPPLGIGRDAVAGDIARAWTLVSRTAMLWLTVMLATAML 314 GALG++LGGAAIYDGEVEQRPPLGIG A DIARAW LV T +LWL ++ A++ Sbjct: 241 GALGISLGGAAIYDGEVEQRPPLGIGPAAAGKDIARAWRLVVLTTVLWLALICIAAVI 298 >ref|YP_001352788.1| cobalamin biosynthesis protein CobD [Janthinobacterium sp. Marseille] gb|ABR88542.1| cobalamin biosynthesis protein CobD [Janthinobacterium sp. Marseille] Length = 313 Score = 386 bits (991), Expect = e-105, Method: Compositional matrix adjust. Identities = 203/296 (68%), Positives = 225/296 (76%) Query: 13 LALLMAAGVALDWLLGETRRWHPLVGFGRYVQCLERRLNRQPGSYARGVFAWLLAVLPPV 72 +A+LM GV LD LGE RWHPLVGFG +E++ N ARG AW+L V P V Sbjct: 10 IAILMLLGVLLDMRLGEATRWHPLVGFGNLAIRIEKKFNTGGSRIARGALAWILVVAPFV 69 Query: 73 ALACAATILLARQSLWLAAAWHVLLLYFCIGLRSLRDHVMPIAAALKDGDLAAARALTGR 132 A+A T +A+ A H LLLYF +GLRSLRDH +PIA AL DGDLA AR LT R Sbjct: 70 AVAWLLTFWVAQFDALFALGVHALLLYFSLGLRSLRDHTLPIAHALMDGDLAQARLLTAR 129 Query: 133 IVSRDTTQSQETDLAKAAVESLLENGNDAVFGTLFWFAVAGGPGALLFRLANTLDAMWGY 192 IVSRDTTQ+QE DLAKA VESLLENGNDAVFGTLFWFAVAGGPG +LFRLANTLDAMWGY Sbjct: 130 IVSRDTTQAQEADLAKAGVESLLENGNDAVFGTLFWFAVAGGPGVVLFRLANTLDAMWGY 189 Query: 193 RTSRFLAFGCAAARLDDALNWIPARLTALSYAALGNWRQARTCWHEQAPAWSSPNAGPVM 252 RT RF FG AAR+DD LN+IPARLTALSYA LGN RQA CW QAPAWSSPNAGPVM Sbjct: 190 RTQRFNEFGRVAARIDDVLNFIPARLTALSYAVLGNTRQAWRCWRAQAPAWSSPNAGPVM 249 Query: 253 SSGAGALGLALGGAAIYDGEVEQRPPLGIGRDAVAGDIARAWTLVSRTAMLWLTVM 308 S+GAGALG++LGGAAIYDGE+EQRPPLG G A DIARAW LV T +LWL ++ Sbjct: 250 SAGAGALGISLGGAAIYDGELEQRPPLGSGPLAAGKDIARAWRLVRLTTVLWLLLI 305 >ref|YP_003776047.1| cobalamin biosynthesis CobD/CbiB [Herbaspirillum seropedicae SmR1] gb|ADJ64139.1| cobalamin biosynthesis (CobD/CbiB) protein [Herbaspirillum seropedicae SmR1] Length = 317 Score = 360 bits (925), Expect = 1e-97, Method: Compositional matrix adjust. Identities = 213/301 (70%), Positives = 235/301 (78%), Gaps = 3/301 (0%) Query: 13 LALLMAAGVALDWLLGETRRWHPLVGFGRYVQCLERRLNRQPGSYARGVFAWLLAVLPPV 72 LA+LMA G+ALD LGE RRWHPLVGFGR Q +E LNR PG RGV AW LAVLPPV Sbjct: 10 LAVLMALGLALDLRLGEARRWHPLVGFGRLAQRIEAALNRAPGLRLRGVLAWALAVLPPV 69 Query: 73 ALACAATILLARQSLWLAAAWHVLLLYFCIGLRSLRDHVMPIAAALKDGDLAAARALTGR 132 LA L+A+ WLAA H LLYFCIGLRSLR+H +PIA AL G+LA AR LT Sbjct: 70 LLA---AWLIAQTPWWLAALLHAGLLYFCIGLRSLREHTLPIAQALGAGELAQARRLTAW 126 Query: 133 IVSRDTTQSQETDLAKAAVESLLENGNDAVFGTLFWFAVAGGPGALLFRLANTLDAMWGY 192 IVSRDT + E +LAKA VESLLENGNDAVFGTLFWF +AGGPGALLFRL+NTLDAMWGY Sbjct: 127 IVSRDTRSASEQELAKAGVESLLENGNDAVFGTLFWFLLAGGPGALLFRLSNTLDAMWGY 186 Query: 193 RTSRFLAFGCAAARLDDALNWIPARLTALSYAALGNWRQARTCWHEQAPAWSSPNAGPVM 252 R +RFL FG AAAR+DDALNW PARLTALSYA LG RQA CW EQAPAWSSPNAGPVM Sbjct: 187 RNARFLYFGWAAARIDDALNWCPARLTALSYAVLGQRRQALACWKEQAPAWSSPNAGPVM 246 Query: 253 SSGAGALGLALGGAAIYDGEVEQRPPLGIGRDAVAGDIARAWTLVSRTAMLWLTVMLATA 312 ++GAGALGLALGGAA+YDGEVEQRPPLG G DI RAW LV+ +A LW+ V+ A A Sbjct: 247 AAGAGALGLALGGAAVYDGEVEQRPPLGCGVAPQGADIVRAWRLVAMSAALWMAVVAAVA 306 Query: 313 M 313 + Sbjct: 307 L 307 >ref|ZP_03270781.1| cobalamin biosynthesis protein CobD [Burkholderia sp. H160] gb|EDZ97632.1| cobalamin biosynthesis protein CobD [Burkholderia sp. H160] Length = 313 Score = 330 bits (846), Expect = 2e-88, Method: Compositional matrix adjust. Identities = 182/295 (61%), Positives = 209/295 (70%), Gaps = 3/295 (1%) Query: 10 MTLLALLMAAGVALDWLLGETRRWHPLVGFGRYVQCLERRLNRQPGSYARGVFAWLLAVL 69 M L+A L AGVA+D GE R HPLVGFG + +E R N +G+FAW LAVL Sbjct: 6 MPLIAALATAGVAVDRWFGEPSRAHPLVGFGNWAARIEARFNHDRRLRLKGLFAWALAVL 65 Query: 70 PPVALACAATILLARQSLWLAAAWHVLLLYFCIGLRSLRDHVMPIAAALKDGDLAAARAL 129 PPV +A L+A L+ A A HV LL+F +G RSLRDH+ PIA AL DLA AR L Sbjct: 66 PPVLIAW---WLVAVLPLFAACALHVALLWFALGARSLRDHIAPIARALGQHDLATARQL 122 Query: 130 TGRIVSRDTTQSQETDLAKAAVESLLENGNDAVFGTLFWFAVAGGPGALLFRLANTLDAM 189 T RIVSRDT QS E LA+AAVES LENGNDA+FG LFWFA+AGGPGAL FRLANTLDAM Sbjct: 123 TARIVSRDTAQSDEAALARAAVESALENGNDAIFGALFWFALAGGPGALGFRLANTLDAM 182 Query: 190 WGYRTSRFLAFGCAAARLDDALNWIPARLTALSYAALGNWRQARTCWHEQAPAWSSPNAG 249 WGYRT R+L FG AAAR+DD LNWIPARLTA SYA LG+ A CW EQAP W SPNAG Sbjct: 183 WGYRTPRYLRFGWAAARIDDVLNWIPARLTATSYALLGDTLTAWRCWREQAPRWDSPNAG 242 Query: 250 PVMSSGAGALGLALGGAAIYDGEVEQRPPLGIGRDAVAGDIARAWTLVSRTAMLW 304 PVM++GAG+L + +GG A+Y G +EQRP LG G A A + A LV RT +LW Sbjct: 243 PVMAAGAGSLNVLIGGPAVYHGTLEQRPTLGFGHPAEARHVGAALMLVERTVILW 297 >ref|YP_003604329.1| cobalamin biosynthesis protein CobD [Burkholderia sp. CCGE1002] gb|ADG14818.1| cobalamin biosynthesis protein CobD [Burkholderia sp. CCGE1002] Length = 313 Score = 328 bits (840), Expect = 9e-88, Method: Compositional matrix adjust. Identities = 181/295 (61%), Positives = 208/295 (70%), Gaps = 3/295 (1%) Query: 10 MTLLALLMAAGVALDWLLGETRRWHPLVGFGRYVQCLERRLNRQPGSYARGVFAWLLAVL 69 M L+A L AGVA+D GE R HPLVGFG + +E R N +G+ AW LAVL Sbjct: 6 MPLIATLAVAGVAVDRWFGEPSRRHPLVGFGNWAARIEARFNHDRRLRLKGLLAWALAVL 65 Query: 70 PPVALACAATILLARQSLWLAAAWHVLLLYFCIGLRSLRDHVMPIAAALKDGDLAAARAL 129 PPV +A L+A L+ A A HV LL+F +G RSLRDH+ PIA AL DLA AR L Sbjct: 66 PPVLIAW---WLVAVLPLFAACALHVALLWFALGARSLRDHIAPIARALGQRDLATAREL 122 Query: 130 TGRIVSRDTTQSQETDLAKAAVESLLENGNDAVFGTLFWFAVAGGPGALLFRLANTLDAM 189 T RIVSRDT+QS E LA+AAVES LENGNDA+FG LFWFA+AGGPGAL FRLANTLDAM Sbjct: 123 TARIVSRDTSQSDEAALARAAVESALENGNDAIFGALFWFALAGGPGALGFRLANTLDAM 182 Query: 190 WGYRTSRFLAFGCAAARLDDALNWIPARLTALSYAALGNWRQARTCWHEQAPAWSSPNAG 249 WGYRT R+L FG AAAR+DD LNWIPARLTA SYA LG+ A CW EQAP W SPNAG Sbjct: 183 WGYRTPRYLRFGWAAARIDDVLNWIPARLTATSYALLGDTLAAWRCWREQAPRWDSPNAG 242 Query: 250 PVMSSGAGALGLALGGAAIYDGEVEQRPPLGIGRDAVAGDIARAWTLVSRTAMLW 304 PVM+SGAG+L + +GG A+Y G +E RP LG G A A + A LV RT +LW Sbjct: 243 PVMASGAGSLNVLIGGPAVYHGTLEHRPTLGFGHPAEARHVGAALMLVERTVILW 297