BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0034.0431.p (379 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_002908345.1| beta-lactamase class C protein [Burkholderia... 282 8e-74 ref|YP_003777556.1| beta-lactamase class C protein [Herbaspirill... 275 1e-71 ref|ZP_00050900.1| COG1680: Beta-lactamase class C and other pen... 245 9e-63 ref|YP_001754347.1| beta-lactamase [Methylobacterium radiotolera... 236 4e-60 ref|ZP_01889203.1| beta-lactamase [unidentified eubacterium SCB4... 227 2e-57 >ref|YP_002908345.1| beta-lactamase class C protein [Burkholderia glumae BGR1] gb|ACR31110.1| beta-lactamase class C protein [Burkholderia glumae BGR1] Length = 387 Score = 282 bits (721), Expect = 8e-74, Method: Compositional matrix adjust. Identities = 150/335 (44%), Positives = 205/335 (61%), Gaps = 9/335 (2%) Query: 44 AAVPAVFEERKIALAPEVAWRDGGRIGFADFLRETHTNAMLVVQHGRLVYEHYPQGGQRA 103 +A P V + V W+ G DFL+ T T A LV+Q G++ YE Y G A Sbjct: 58 SAQPLVLNTAEPRFNHAVTWK-GADSNVDDFLKNTQTRAFLVIQDGKIAYERYANGYSAA 116 Query: 104 AVFPSYSVAKSMLSDLVGVALAEGKIAALSDPVRKYLP--DLPEKFAAVTVDDLLNMHSG 161 + F SYSVAKS ++ +VG AL +G+I +L DP+ YL D+ E++ VT++ LL+M SG Sbjct: 117 SKFASYSVAKSFVATMVGAALFDGRIHSLQDPIGNYLEPGDVREQYRRVTIEQLLSMRSG 176 Query: 162 IRVEEKYDSAFSQIAFMYITTDLNRFMRGLDKTAFTPGQGFAYRSVDYLLLGMVLSAATG 221 I E YDSAF+ + MY+TTDLNRF+ + PGQ F YRSVD L+L VL+ ATG Sbjct: 177 IDAAESYDSAFAPVVQMYLTTDLNRFLSRVSGFRHPPGQEFEYRSVDTLVLSKVLTRATG 236 Query: 222 EPLTRYLERKLWQPMGAAYGAGWSVDNKKHSVEKSFCCVNARAVDFARYGLLHLRQGRAG 281 PL+ Y ++KLW P+GA+ A WS+D+ H VEKSFCC+NA A DFA+ GLL+L +G Sbjct: 237 VPLSAYAQQKLWTPLGASSDASWSLDSATHGVEKSFCCLNATARDFAKLGLLYLAEGDLA 296 Query: 282 NVQVLPAAWMQRPPEVGAADADFAYGRGWWLPRQPAARDGGSAPRDYTAIGIHGQYVYID 341 +++ W P + AY GWW+P RD RD+ AIGI+GQ+VY++ Sbjct: 297 GHRIVSRDWALAPGKSPNPTDALAYFDGWWIPPN-HGRD-----RDFAAIGIYGQFVYVN 350 Query: 342 PVSDTVIVKLSDHGNEQDEALTVAAFRSIVAALPA 376 P + T IVKLS++G EQDE T+ A R I ++ A Sbjct: 351 PSTHTTIVKLSEYGAEQDELDTLLAMRQIAHSITA 385 >ref|YP_003777556.1| beta-lactamase class C protein [Herbaspirillum seropedicae SmR1] gb|ADJ65648.1| beta-lactamase class C protein [Herbaspirillum seropedicae SmR1] Length = 403 Score = 275 bits (703), Expect = 1e-71, Method: Compositional matrix adjust. Identities = 142/318 (44%), Positives = 200/318 (62%), Gaps = 9/318 (2%) Query: 56 ALAPEVAWRDGGRIGFADFLRETHTNAMLVVQHGRLVYEHYPQGGQRAAVFPSYSVAKSM 115 AL V W+DG ++ DFL+ T +A +V+Q G++VYE Y G + F S+SVAKS Sbjct: 76 ALEISVPWKDGSQLPVIDFLKTTSAHAFVVIQDGKIVYERYIDGYDANSRFTSFSVAKSF 135 Query: 116 LSDLVGVALAEGKIAALSDPVRKYL--PDLPEKFAAVTVDDLLNMHSGIRVEEKYDSAF- 172 +S L GVAL +GKI +L +P+ YL ++ +A +T+ LL+M SGI V+E Y + Sbjct: 136 VSALTGVALQQGKIRSLDEPIGHYLNSDEIAPAYAGITIGQLLDMRSGIDVDENYGGSLA 195 Query: 173 SQIAFMYITTDLNRFMRGLDKTAFTPGQGFAYRSVDYLLLGMVLSAATGEPLTRYLERKL 232 S + M+++TDL+RF+ F PG F YRSVD L+L VL+ ATG L+ + ++ L Sbjct: 196 SPVVRMFVSTDLHRFIARRSGLRFAPGSRFEYRSVDTLVLSRVLAHATGMRLSDFAQQVL 255 Query: 233 WQPMGAAYGAGWSVDNKKHSVEKSFCCVNARAVDFARYGLLHLRQGRAGNVQVLPAAWMQ 292 W+P+G A WSVD+ +H VEK+FCC+N A DFAR GLL+L GR G+ QV+ +W Sbjct: 256 WEPLGMEQDASWSVDSGQHGVEKAFCCLNTTARDFARLGLLYLDGGRVGDQQVVSPSWAH 315 Query: 293 RPPEVGAADADFAYGRGWWLPRQPAARDGGSAPRDYTAIGIHGQYVYIDPVSDTVIVKLS 352 P + Y GWW+P G + RD++AIG+ GQY+Y++P + TVIVKLS Sbjct: 316 EPRQPVNHGEVLDYRDGWWIP------PGNADDRDFSAIGVFGQYIYVNPATRTVIVKLS 369 Query: 353 DHGNEQDEALTVAAFRSI 370 D+G EQDE LT+ A RSI Sbjct: 370 DYGVEQDEVLTMLAMRSI 387 >ref|ZP_00050900.1| COG1680: Beta-lactamase class C and other penicillin binding proteins [Magnetospirillum magnetotacticum MS-1] Length = 403 Score = 245 bits (626), Expect = 9e-63, Method: Compositional matrix adjust. Identities = 148/345 (42%), Positives = 202/345 (58%), Gaps = 17/345 (4%) Query: 39 LKNPAAAVPAVFEERKIALAPEVAWRDGGRIGFADFLRETHTNAMLVVQHGRLVYEHYPQ 98 ++ P A F R I V W+ G I L THTNA LV Q G L++E Y Sbjct: 70 VQAPTKARELPFRSRPIL--DRVVWK-GKTIPLGTVLDATHTNAFLVAQDGVLIHEWYRS 126 Query: 99 GGQRAAVFPSYSVAKSMLSDLVGVALAEGKIAALSDPVRKYLPDL--PEKFAAVTVDDLL 156 G A +FPS+SVAKS++S LVG A+A GK++ +D V LP+L P F+ +TV +LL Sbjct: 127 GRDEATLFPSWSVAKSIVSLLVGSAVARGKLSE-TDKVSMLLPELRHPGVFSQITVRNLL 185 Query: 157 NMHSGIRVEEKYDSA--FSQIAFMYITTDLNRFMRGLDKTAFTPGQGFAYRSVDYLLLGM 214 +M SGI V E YD + + A MY+T D+ F+R AF PG YRS+D +LG+ Sbjct: 186 DMTSGIAVPENYDPSHPLTGTAGMYLTRDITAFVRDNAHLAFKPGSEGRYRSIDTEVLGL 245 Query: 215 VLSAATGEPLTRYLERKLWQPMGAAYGAGWSVDNKKHSVEKSFCCVNARAVDFARYGLLH 274 +L+ G+PL L ++W+P+GA A W++D + VEK+FCC+NA A DFAR GLL Sbjct: 246 ILARVEGKPLADLLSERIWKPIGAQADATWNLD-RPGGVEKAFCCINATARDFARLGLLV 304 Query: 275 LRQGRAGNVQVLPAAWMQRPPEVGAADAD-FAYGRGWWLPRQPAARDGGSAPRDYTAIGI 333 QGRAG +++P W++R D + Y WW A DG D +AIG+ Sbjct: 305 ADQGRAGEARIVPMRWIERISTPARRSVDGWRYSAQWW-----HAPDGDE--DDISAIGV 357 Query: 334 HGQYVYIDPVSDTVIVKLSDHGNEQDEALTVAAFRSIVAALPATA 378 +GQYVY++ + TVIVKLSDHG EQDE T+A ++I A L A + Sbjct: 358 YGQYVYVNRNTGTVIVKLSDHGAEQDETDTLAVMQAIAADLAAKS 402 >ref|YP_001754347.1| beta-lactamase [Methylobacterium radiotolerans JCM 2831] gb|ACB23664.1| beta-lactamase [Methylobacterium radiotolerans JCM 2831] Length = 410 Score = 236 bits (602), Expect = 4e-60, Method: Compositional matrix adjust. Identities = 138/321 (42%), Positives = 189/321 (58%), Gaps = 15/321 (4%) Query: 61 VAWRDGGRIGFADFLRETHTNAMLVVQHGRLVYEHYPQGGQRAAVFPSYSVAKSMLSDLV 120 V W+ G + L THTNA LV+Q G L++E G +FPS+SVAKS++S LV Sbjct: 90 VPWK-GKTVPLMTVLGATHTNAFLVLQDGVLIHEWQRAGTGPETLFPSWSVAKSVVSLLV 148 Query: 121 GVALAEGKIAALSDPVRKYLPDLPEK--FAAVTVDDLLNMHSGIRVEEKYDS--AFSQIA 176 G A+A G++A +D V LP+L F +TV +LL+M SGI V E YD + A Sbjct: 149 GAAVARGQLAE-TDRVSTLLPELRNGAVFGQITVRNLLDMASGIAVPENYDPRHPLTGTA 207 Query: 177 FMYITTDLNRFMRGLDKTAFTPGQGFAYRSVDYLLLGMVLSAATGEPLTRYLERKLWQPM 236 MY+T DL F+R AF PG YRS+D LLG++L+ G+PL L ++W+PM Sbjct: 208 GMYLTRDLTAFVRDNAHLAFKPGTKGRYRSIDTELLGLILARVEGKPLADILSERIWKPM 267 Query: 237 GAAYGAGWSVDNKKHSVEKSFCCVNARAVDFARYGLLHLRQGRAGNVQVLPAAWMQRPPE 296 GA A W++D + +EK+FCC+NA A DFAR GLL QGR+G +++P W++R Sbjct: 268 GAQADATWNLD-RPGGIEKAFCCINATARDFARLGLLVADQGRSGEHRIIPGRWIERIMT 326 Query: 297 VGAADAD-FAYGRGWWLPRQPAARDGGSAPRDYTAIGIHGQYVYIDPVSDTVIVKLSDHG 355 D D + Y WW P D D +AIG++GQY+Y++ + TVIVKLSDHG Sbjct: 327 PARRDVDGWQYSAQWW--HAPGGEDD-----DISAIGVYGQYIYVNRATGTVIVKLSDHG 379 Query: 356 NEQDEALTVAAFRSIVAALPA 376 EQDE T+A ++I L A Sbjct: 380 AEQDEVDTLAVMQAIAGDLAA 400 >ref|ZP_01889203.1| beta-lactamase [unidentified eubacterium SCB49] gb|EDM45333.1| beta-lactamase [unidentified eubacterium SCB49] Length = 372 Score = 227 bits (579), Expect = 2e-57, Method: Compositional matrix adjust. Identities = 123/310 (39%), Positives = 182/310 (58%), Gaps = 15/310 (4%) Query: 68 RIGFADFLRETHTNAMLVVQHGRLVYEHYPQGGQRAAVFPSYSVAKSMLSDLVGVALAEG 127 ++ F D+L T A LVVQ+ + YE Y + A++ S+S+AKS+LS LVG+A+ EG Sbjct: 75 KVTFEDYLISNKTVAYLVVQNDTIKYEQYFNKYEEASIVNSFSMAKSILSMLVGIAVYEG 134 Query: 128 KIAALSDPVRKYLPDLPE-KFAAVTVDDLLNMHSGIRVEEKYDSAFSQIAFMYITTDLNR 186 KI ++++PV YL +L + F VT++ LLNM SGI E Y + F A Y T+L + Sbjct: 135 KIKSINEPVTNYLTELEDPAFKDVTIEHLLNMTSGIAFNESYVNPFGDAATFYYGTNLRK 194 Query: 187 FMRGLDKTAFTPGQGFAYRSVDYLLLGMVLSAATGEP-LTRYLERKLWQPMGAAYGAGWS 245 + G+ K TPG F Y S D +LGMVL AA E ++ YLE K+WQP+G Y A WS Sbjct: 195 AVNGM-KIEATPGSSFKYSSGDSQVLGMVLEAALKETTISEYLEEKIWQPLGMEYDATWS 253 Query: 246 VDNKKHSVEKSFCCVNARAVDFARYGLLHLRQGRAGNVQVLPAAWMQRPPEVGAADADFA 305 +D +K VEK+FCC+NARA DFA+ G L+L +G Q++ W+++ ++ + + A Sbjct: 254 LDREKKGVEKTFCCLNARARDFAKLGRLYLNKGNWNGKQIVSKDWVEKSTKIDSTGGNVA 313 Query: 306 -YGRGWWLPRQPAARDGGSAPRDYTAIGIHGQYVYIDPVSDTVIVKLSDHGNEQDEALTV 364 Y WWL + + + AIGI GQ++Y++P + VIV+L + E V Sbjct: 314 YYQHQWWLNEKDNS---------FEAIGILGQHIYVNPEKNIVIVRLGEKNGENGAWTQV 364 Query: 365 AAFRSIVAAL 374 A +SI + L Sbjct: 365 A--QSIASKL 372