BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0034.0391.p (429 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_002006161.1| transporter; major facilitator superfamily (... 476 e-132 ref|YP_004686359.1| monocarboxylate transporter [Cupriavidus nec... 471 e-131 ref|YP_727118.1| putative monocarboxylate transporter [Ralstonia... 469 e-130 ref|YP_584668.1| major facilitator superfamily transporter [Cupr... 464 e-129 ref|YP_001021748.1| putative MFS transporter [Methylibium petrol... 460 e-127 >ref|YP_002006161.1| transporter; major facilitator superfamily (mfs) [Cupriavidus taiwanensis LMG 19424] emb|CAQ70098.1| putative transporter; Major facilitator superfamily (MFS) [Cupriavidus taiwanensis LMG 19424] Length = 403 Score = 476 bits (1224), Expect = e-132, Method: Compositional matrix adjust. Identities = 237/397 (59%), Positives = 295/397 (74%), Gaps = 2/397 (0%) Query: 4 SERAPDFKTVLLASGLVLTLAMGVRHGLGFWLQPISQAHGWTRETFSLAIALQNLMWGVF 63 R TVL+ GL++TL+MG+RHG G + PI+QAHGW RETF+ A+ALQNLMWG Sbjct: 2 QNRQLSLTTVLVCGGLLVTLSMGIRHGFGLFNLPITQAHGWNRETFAFALALQNLMWGAS 61 Query: 64 GPFAGMAADRYGTARVIVIGALLYMGGLLWMALVDQPMLFAVGSGVLIGAALSCTAFGAI 123 PFAG AD++G R++++G LY+ GL+ MAL FA G+GV+IG A S T + + Sbjct: 62 QPFAGALADKFGALRIMLVGVALYVAGLVVMALATSGTAFATGAGVMIGIAQSGTTYSIV 121 Query: 124 SGIVGRSAPPEKRSLAFGISSAAGSFGQFVMMPVEQQLISVTGWQQAFYWLSALVVAVMV 183 G++GR A PEKR A GI++AAGSFGQF+M+PVEQ LIS GWQ A Y + AL+ VM+ Sbjct: 122 YGVIGRVASPEKRVWAMGIAAAAGSFGQFLMIPVEQGLISGLGWQNALY-VMALMACVML 180 Query: 184 PMAFRLREPK-LAHSGKQEQSIWEATREAFAYRPFQFLIAGYFVCGFQVVFIGAHLPSYL 242 P+A LREP+ AHSG Q+I +A EAF R FQ L GYFVCGFQVVFIG HL YL Sbjct: 181 PLALTLREPREAAHSGGHHQTIGQAIHEAFGNRNFQLLTLGYFVCGFQVVFIGVHLAPYL 240 Query: 243 KDKGLMDPNIAVAALALIGLFNIFGSYYAGKLGGFLPKRYLLSTIYFSRTVAISLFLLAP 302 KD+GL DP +AV ALALIGLFN+FG+Y AG +G LPKRYLL+ IY +R+V I+ +LL P Sbjct: 241 KDQGLTDPKVAVVALALIGLFNVFGTYTAGAMGQRLPKRYLLAAIYLARSVVIAAYLLLP 300 Query: 303 LSSWSVYIFSAAMGLLWLSTVPLTNGIIAGIFGLKHLSMLSGFVFLSHQIGSFLGVWLGG 362 L+ S ++F+A MG LWLSTVPLTNGIIA +FG+K+LSMLSG VF SHQIGSFLG WLGG Sbjct: 301 LTVASTWVFAAVMGFLWLSTVPLTNGIIAQVFGVKYLSMLSGVVFFSHQIGSFLGAWLGG 360 Query: 363 YLFTREGSYNTVWMITIGLGLFATVMNLPVNEKAIRR 399 YL+ R G YNTVWMI IGLG+ A ++NLP+ E+A+ R Sbjct: 361 YLYDRTGGYNTVWMIAIGLGVLAALVNLPIREQAVVR 397 >ref|YP_004686359.1| monocarboxylate transporter [Cupriavidus necator N-1] gb|AEI77878.1| monocarboxylate transporter [Cupriavidus necator N-1] Length = 403 Score = 471 bits (1212), Expect = e-131, Method: Compositional matrix adjust. Identities = 236/397 (59%), Positives = 295/397 (74%), Gaps = 2/397 (0%) Query: 4 SERAPDFKTVLLASGLVLTLAMGVRHGLGFWLQPISQAHGWTRETFSLAIALQNLMWGVF 63 R TVL+ GL++TL+MG+RHG G + PI+QAHGW RETF+ A+ALQNLMWG Sbjct: 2 QNRQLSLTTVLVCGGLLVTLSMGIRHGFGLFNLPITQAHGWNRETFAFALALQNLMWGAS 61 Query: 64 GPFAGMAADRYGTARVIVIGALLYMGGLLWMALVDQPMLFAVGSGVLIGAALSCTAFGAI 123 PFAG AD++G R++++G LY+ GL+ MAL FA G+GV+IG A S T + + Sbjct: 62 QPFAGALADKFGALRIMLVGVALYVAGLVVMALATSGTAFATGAGVMIGIAQSGTTYSIV 121 Query: 124 SGIVGRSAPPEKRSLAFGISSAAGSFGQFVMMPVEQQLISVTGWQQAFYWLSALVVAVMV 183 G++GR A PEKR A GI++AAGSFGQF+M+PVEQ LIS GWQ A Y + AL+ VM+ Sbjct: 122 YGVIGRVASPEKRVWAMGIAAAAGSFGQFLMIPVEQGLISGLGWQNALY-VMALMACVML 180 Query: 184 PMAFRLREPK-LAHSGKQEQSIWEATREAFAYRPFQFLIAGYFVCGFQVVFIGAHLPSYL 242 P+A LREP+ AH+G Q+I +A EAF R FQ L GYFVCGFQVVFIG HL YL Sbjct: 181 PLALTLREPREAAHTGGHHQTIGQAVHEAFGNRNFQLLTLGYFVCGFQVVFIGVHLAPYL 240 Query: 243 KDKGLMDPNIAVAALALIGLFNIFGSYYAGKLGGFLPKRYLLSTIYFSRTVAISLFLLAP 302 KD+GL DP +AV ALALIGLFN+FG+Y AG LG LPKRYLLS IY +R+V I+ +LL P Sbjct: 241 KDQGLTDPKVAVVALALIGLFNVFGTYTAGALGQRLPKRYLLSAIYVTRSVVIAGYLLLP 300 Query: 303 LSSWSVYIFSAAMGLLWLSTVPLTNGIIAGIFGLKHLSMLSGFVFLSHQIGSFLGVWLGG 362 L+ S ++F+A MG LWLSTVPLTNGIIA +FG+K+LSMLSG VF SHQIGSFLG WLGG Sbjct: 301 LTVASTWVFAALMGFLWLSTVPLTNGIIAQVFGVKYLSMLSGVVFFSHQIGSFLGAWLGG 360 Query: 363 YLFTREGSYNTVWMITIGLGLFATVMNLPVNEKAIRR 399 YL+ R G YNTVW+I+I LG+ A ++NLP+ E+A+ R Sbjct: 361 YLYDRTGGYNTVWLISIALGVVAALVNLPIREQALVR 397 >ref|YP_727118.1| putative monocarboxylate transporter [Ralstonia eutropha H16] emb|CAJ93750.1| putative monocarboxylate transporter [Ralstonia eutropha H16] Length = 491 Score = 469 bits (1207), Expect = e-130, Method: Compositional matrix adjust. Identities = 235/397 (59%), Positives = 294/397 (74%), Gaps = 2/397 (0%) Query: 4 SERAPDFKTVLLASGLVLTLAMGVRHGLGFWLQPISQAHGWTRETFSLAIALQNLMWGVF 63 R TVL+ GL++TL+MG+RHG G + PI+QAHGW RETF+ A+ALQNLMWG Sbjct: 90 QNRQLSLTTVLVCGGLLVTLSMGIRHGFGLFNLPITQAHGWNRETFAFALALQNLMWGAS 149 Query: 64 GPFAGMAADRYGTARVIVIGALLYMGGLLWMALVDQPMLFAVGSGVLIGAALSCTAFGAI 123 PFAG AD++G R++++G LY+ GL+ MAL FA G+GV+IG A S T + + Sbjct: 150 QPFAGALADKFGALRIMLVGVALYVAGLVVMALATSGTAFATGAGVMIGIAQSGTTYSIV 209 Query: 124 SGIVGRSAPPEKRSLAFGISSAAGSFGQFVMMPVEQQLISVTGWQQAFYWLSALVVAVMV 183 G++GR A PEKR A GI++AAGSFGQF+M+PVEQ LIS GWQ A Y + AL+ VM+ Sbjct: 210 YGVIGRVASPEKRVWAMGIAAAAGSFGQFLMIPVEQGLISGLGWQNALYVM-ALMACVML 268 Query: 184 PMAFRLREPK-LAHSGKQEQSIWEATREAFAYRPFQFLIAGYFVCGFQVVFIGAHLPSYL 242 P+A LREP+ AH+G Q+I +A EAF R FQ L GYFVCGFQVVFIG HL YL Sbjct: 269 PLALTLREPREAAHTGGHHQTIGQAVHEAFGNRNFQLLTLGYFVCGFQVVFIGVHLAPYL 328 Query: 243 KDKGLMDPNIAVAALALIGLFNIFGSYYAGKLGGFLPKRYLLSTIYFSRTVAISLFLLAP 302 KD+GL DP +AV ALALIGLFN+FG+Y AG LG LPKRYLLS IY +R+V I+ +LL P Sbjct: 329 KDQGLTDPKVAVVALALIGLFNVFGTYTAGALGQRLPKRYLLSAIYVTRSVVIASYLLLP 388 Query: 303 LSSWSVYIFSAAMGLLWLSTVPLTNGIIAGIFGLKHLSMLSGFVFLSHQIGSFLGVWLGG 362 L+ S ++F+A MG LWLSTVPLTNGIIA +FG+K+LSMLSG VF SHQIGSFLG WLGG Sbjct: 389 LTVASTWVFAAVMGFLWLSTVPLTNGIIAQVFGVKYLSMLSGVVFFSHQIGSFLGAWLGG 448 Query: 363 YLFTREGSYNTVWMITIGLGLFATVMNLPVNEKAIRR 399 +L+ R G YNTVW+I I LG+ A ++NLP+ E+A+ R Sbjct: 449 FLYDRTGGYNTVWLIAIALGVVAALVNLPIREQALVR 485 >ref|YP_584668.1| major facilitator superfamily transporter [Cupriavidus metallidurans CH34] gb|ABF09399.1| Major facilitator superfamily MFS_1 precursor [Cupriavidus metallidurans CH34] Length = 403 Score = 464 bits (1195), Expect = e-129, Method: Compositional matrix adjust. Identities = 232/397 (58%), Positives = 291/397 (73%), Gaps = 2/397 (0%) Query: 4 SERAPDFKTVLLASGLVLTLAMGVRHGLGFWLQPISQAHGWTRETFSLAIALQNLMWGVF 63 ++R TVL+ GL++TL+MG+RHG G + PI+Q HGW+RETF+ A+ALQNLMWG Sbjct: 2 TDRKLSLTTVLVCGGLLVTLSMGIRHGFGLFNLPITQTHGWSRETFAFALALQNLMWGAS 61 Query: 64 GPFAGMAADRYGTARVIVIGALLYMGGLLWMALVDQPMLFAVGSGVLIGAALSCTAFGAI 123 P G AD++G R+++IG LY+ GL+ M L FA G+GVLIG A S T + + Sbjct: 62 QPITGALADKFGALRIMIIGVALYVAGLIVMGLATSGTAFATGAGVLIGIAQSGTTYSVV 121 Query: 124 SGIVGRSAPPEKRSLAFGISSAAGSFGQFVMMPVEQQLISVTGWQQAFYWLSALVVAVMV 183 G++GR A EKR A GI++AAGSFGQF+M+PVEQ LIS GWQ A + L A + M+ Sbjct: 122 YGVIGRVASAEKRVWAMGIAAAAGSFGQFLMIPVEQTLISTMGWQNALFIL-AFLACFML 180 Query: 184 PMAFRLREPKL-AHSGKQEQSIWEATREAFAYRPFQFLIAGYFVCGFQVVFIGAHLPSYL 242 P+A LREPK+ A + Q+I EATREAF R FQ L GYFVCGFQVVFIG HL YL Sbjct: 181 PLALTLREPKMVATTTGHHQTIGEATREAFGNRNFQLLTLGYFVCGFQVVFIGVHLAPYL 240 Query: 243 KDKGLMDPNIAVAALALIGLFNIFGSYYAGKLGGFLPKRYLLSTIYFSRTVAISLFLLAP 302 KD+G DP +A ALALIGLFN+FG+Y AG +G +PKRYLLS IY +R+V I+ +LL P Sbjct: 241 KDRGFTDPKVATVALALIGLFNVFGTYTAGSMGQRMPKRYLLSFIYIARSVVIAGYLLMP 300 Query: 303 LSSWSVYIFSAAMGLLWLSTVPLTNGIIAGIFGLKHLSMLSGFVFLSHQIGSFLGVWLGG 362 L++ S ++F+A MG LWLSTVPLTNGIIA +FG+K+LSMLSG VF SHQIGSFLG WLGG Sbjct: 301 LTAASTWVFAALMGFLWLSTVPLTNGIIAQVFGVKYLSMLSGVVFFSHQIGSFLGAWLGG 360 Query: 363 YLFTREGSYNTVWMITIGLGLFATVMNLPVNEKAIRR 399 YLF + GSY+TVWMI I LGL A V+NLP+ E+A+ R Sbjct: 361 YLFDKTGSYSTVWMIAIALGLMAAVVNLPIREQALVR 397 >ref|YP_001021748.1| putative MFS transporter [Methylibium petroleiphilum PM1] gb|ABM95513.1| putative MFS transporter [Methylibium petroleiphilum PM1] Length = 407 Score = 460 bits (1183), Expect = e-127, Method: Compositional matrix adjust. Identities = 237/402 (58%), Positives = 293/402 (72%), Gaps = 5/402 (1%) Query: 1 MFHSERAP---DFKTVLLASGLVLTLAMGVRHGLGFWLQPISQAHGWTRETFSLAIALQN 57 M RAP VLL ++TL+MG+RHG G WLQPI+ GW+RETF LA+A+QN Sbjct: 1 MTSPTRAPHTLSMTQVLLCGAAIVTLSMGIRHGFGLWLQPITMDRGWSRETFGLALAIQN 60 Query: 58 LMWGVFGPFAGMAADRYGTARVIVIGALLYMGGLLWMALVDQPMLFAVGSGVLIGAALSC 117 L WG+ GPFAGM ADRYG +V+V G++LY GGL+ MAL + F +G++IG A + Sbjct: 61 LSWGLVGPFAGMLADRYGAFKVLVAGSVLYAGGLVLMALATSGLAFHGSAGLMIGMAQAG 120 Query: 118 TAFGAISGIVGRSAPPEKRSLAFGISSAAGSFGQFVMMPVEQQLISVTGWQQAFYWLSAL 177 + + G++GR+ PEKRS A GI++AAGSFGQF+M+PVE LIS GWQ+A L Sbjct: 121 CTYAIVYGVIGRNVAPEKRSWAMGITAAAGSFGQFLMVPVESGLISAFGWQEALILLGCA 180 Query: 178 VVAVMVPMAFRLREPKLAHSGKQEQSIWEATREAFAYRPFQFLIAGYFVCGFQVVFIGAH 237 +A+ VP+AF L+EPKLA ++QSI EA REAF YR FQ L+AGYFVCGFQVVFIG H Sbjct: 181 ALAI-VPLAFGLKEPKLAPPAGRQQSIGEAVREAFGYRSFQLLMAGYFVCGFQVVFIGVH 239 Query: 238 LPSYLKDKGLMDPNIAVAALALIGLFNIFGSYYAGKLGGFLPKRYLLSTIYFSRTVAISL 297 +PSYLKD GL P +A ALALIGLFN+FG+Y AG LG L KR++L++IY R+VAI Sbjct: 240 MPSYLKDHGL-SPQVATTALALIGLFNVFGTYAAGVLGQRLAKRHILASIYALRSVAIIA 298 Query: 298 FLLAPLSSWSVYIFSAAMGLLWLSTVPLTNGIIAGIFGLKHLSMLSGFVFLSHQIGSFLG 357 FLL PL+ SVY FS AMGLLWLSTVP TN ++A IFG+KH SML GFVFL+HQIGSFLG Sbjct: 299 FLLLPLTPASVYAFSIAMGLLWLSTVPTTNAVVAQIFGVKHFSMLGGFVFLAHQIGSFLG 358 Query: 358 VWLGGYLFTREGSYNTVWMITIGLGLFATVMNLPVNEKAIRR 399 VWLGG L+ GSY+ VW I + LG+FA ++NLPV E AI R Sbjct: 359 VWLGGKLYDATGSYDVVWWIAVALGVFAALINLPVRETAIVR 400