BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0034.0277.p (338 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003773585.1| delta-aminolevulinic acid dehydratase [Herba... 561 e-158 ref|YP_001101366.1| delta-aminolevulinic acid dehydratase [Hermi... 543 e-152 ref|YP_001355068.1| delta-aminolevulinic acid dehydratase [Janth... 542 e-152 ref|YP_004751095.1| porphobilinogen synthase [Collimonas fungivo... 540 e-151 ref|ZP_08274537.1| Porphobilinogen synthase [Oxalobacteraceae ba... 521 e-146 >ref|YP_003773585.1| delta-aminolevulinic acid dehydratase [Herbaspirillum seropedicae SmR1] gb|ADJ61677.1| delta-aminolevulinic acid dehydratase protein [Herbaspirillum seropedicae SmR1] Length = 339 Score = 561 bits (1447), Expect = e-158, Method: Compositional matrix adjust. Identities = 272/319 (85%), Positives = 292/319 (91%) Query: 1 MSLTSTSTSAQFPAIRMRRMRKDAFSRAMMQENVITPADLIYPVFIQEGQNLRTPVGSLP 60 MSLT S++A +PA+RMRRMR+DAFSRA+M ENVIT ADLIYPVF+QEGQNLRTPV SLP Sbjct: 1 MSLTDFSSNAGYPALRMRRMRRDAFSRALMAENVITSADLIYPVFVQEGQNLRTPVASLP 60 Query: 61 GVERLSIDQLLHVAEDTVALGIPVLALFPVIDVALKTPDGIEAINPDGLVPRAVAALKQR 120 GVERLS+D LL VAE+ V LG+PVLALFPVID ALKTPDGIEA NPDGLVPR V ALK R Sbjct: 61 GVERLSLDTLLPVAEECVKLGVPVLALFPVIDPALKTPDGIEATNPDGLVPRVVRALKDR 120 Query: 121 FPELGILTDVALDPYTSHGQDGVMDDNGYVLNDETTALLVRQALAQAQAGVDIVAPSDMM 180 FPELG+L DVALDPYTSHGQDGV+D+ GY+LNDET ALLV+QA QA AGVD+VAPSDMM Sbjct: 121 FPELGVLCDVALDPYTSHGQDGVLDETGYILNDETLALLVKQAQTQADAGVDVVAPSDMM 180 Query: 181 DGRIGAVRDALEAEKFIYTRIMAYSAKYASAFYGPFRDAVGSAANLGKGSKSTYQMDPAN 240 DGRI A+R LEA+ IYTRIMAYSAKYASAFYGPFRDAVGSAANLGKGSK+TYQMDPAN Sbjct: 181 DGRIAAIRAMLEAQDHIYTRIMAYSAKYASAFYGPFRDAVGSAANLGKGSKATYQMDPAN 240 Query: 241 SDEALREVALDLQEGADMVMVKPGMPYLDIVRRVKDEFKVPTFAYQVSGEYAMIKAAAQN 300 SDEALREVALDLQEGADMVMVKPGMPYLDIVRRVKDEF+VPTFAYQVSGEYAMIKAAAQN Sbjct: 241 SDEALREVALDLQEGADMVMVKPGMPYLDIVRRVKDEFRVPTFAYQVSGEYAMIKAAAQN 300 Query: 301 GWLDHDKAMMEAMMAFKRA 319 GWLDHDK MMEAMMAFKRA Sbjct: 301 GWLDHDKTMMEAMMAFKRA 319 >ref|YP_001101366.1| delta-aminolevulinic acid dehydratase [Herminiimonas arsenicoxydans] emb|CAL63245.1| Delta-aminolevulinic acid dehydratase (Porphobilinogen synthase) (ALAD) (ALADH) [Herminiimonas arsenicoxydans] Length = 337 Score = 543 bits (1398), Expect = e-152, Method: Compositional matrix adjust. Identities = 257/312 (82%), Positives = 284/312 (91%) Query: 8 TSAQFPAIRMRRMRKDAFSRAMMQENVITPADLIYPVFIQEGQNLRTPVGSLPGVERLSI 67 ++AQFPA+RMRRMRKDAFSRAMM+ENV+TPADLIYPVF+ EG+N + S+PGVERLS+ Sbjct: 6 SNAQFPAVRMRRMRKDAFSRAMMRENVLTPADLIYPVFVTEGKNQSEKISSMPGVERLSV 65 Query: 68 DQLLHVAEDTVALGIPVLALFPVIDVALKTPDGIEAINPDGLVPRAVAALKQRFPELGIL 127 D LL VAE+ V+L IPVLALFPVI+ +LKTPDGIEA NPDGLVPRAV LK+ FPELGIL Sbjct: 66 DLLLSVAEECVSLHIPVLALFPVINASLKTPDGIEACNPDGLVPRAVRELKKHFPELGIL 125 Query: 128 TDVALDPYTSHGQDGVMDDNGYVLNDETTALLVRQALAQAQAGVDIVAPSDMMDGRIGAV 187 TD+ALDPYTSHGQDGV+D NGYVLNDET ++L +QAL A+AGVDIVAPSDMMDGRIGA+ Sbjct: 126 TDIALDPYTSHGQDGVLDANGYVLNDETCSILTKQALTHAEAGVDIVAPSDMMDGRIGAI 185 Query: 188 RDALEAEKFIYTRIMAYSAKYASAFYGPFRDAVGSAANLGKGSKSTYQMDPANSDEALRE 247 R+ALEA IYTRIMAYSAKYASAFYGPFRDAVGS+A LGK +K+TYQMDPANSDEALRE Sbjct: 186 RNALEAHHHIYTRIMAYSAKYASAFYGPFRDAVGSSATLGKSNKATYQMDPANSDEALRE 245 Query: 248 VALDLQEGADMVMVKPGMPYLDIVRRVKDEFKVPTFAYQVSGEYAMIKAAAQNGWLDHDK 307 VALDL EGADMVMVKPGMPYLDIVRRVKDEFKVPTFAYQVSGEYAMIKAAAQ GWLDHDK Sbjct: 246 VALDLAEGADMVMVKPGMPYLDIVRRVKDEFKVPTFAYQVSGEYAMIKAAAQQGWLDHDK 305 Query: 308 AMMEAMMAFKRA 319 MMEAM+AFKRA Sbjct: 306 TMMEAMIAFKRA 317 >ref|YP_001355068.1| delta-aminolevulinic acid dehydratase [Janthinobacterium sp. Marseille] gb|ABR88657.1| porphobilinogen synthase [Janthinobacterium sp. Marseille] Length = 337 Score = 542 bits (1396), Expect = e-152, Method: Compositional matrix adjust. Identities = 260/311 (83%), Positives = 283/311 (90%) Query: 9 SAQFPAIRMRRMRKDAFSRAMMQENVITPADLIYPVFIQEGQNLRTPVGSLPGVERLSID 68 +AQFPA+RMRRMRKDAFSRAMM+E+V+T ADLIYPVFI EG+N R V S+PGVERLS+D Sbjct: 7 NAQFPALRMRRMRKDAFSRAMMREHVVTAADLIYPVFITEGENQREKVSSMPGVERLSVD 66 Query: 69 QLLHVAEDTVALGIPVLALFPVIDVALKTPDGIEAINPDGLVPRAVAALKQRFPELGILT 128 LL VAE+ V L IPV+ALFPVI +LKTPDGIEA NP+GLVPRAV LK+RFPELGILT Sbjct: 67 LLLSVAEECVELNIPVMALFPVIQASLKTPDGIEACNPNGLVPRAVRELKKRFPELGILT 126 Query: 129 DVALDPYTSHGQDGVMDDNGYVLNDETTALLVRQALAQAQAGVDIVAPSDMMDGRIGAVR 188 DVALDPYTSHGQDGV+D +GYVLNDET A+L +QALAQA+AGVDIVAPSDMMDGRIGA+R Sbjct: 127 DVALDPYTSHGQDGVLDAHGYVLNDETCAILTKQALAQAEAGVDIVAPSDMMDGRIGAIR 186 Query: 189 DALEAEKFIYTRIMAYSAKYASAFYGPFRDAVGSAANLGKGSKSTYQMDPANSDEALREV 248 ALE+ IYTRIMAYSAKYASAFYGPFRDAVGS+A LGK +KSTYQMDPANSDEALREV Sbjct: 187 SALESHHHIYTRIMAYSAKYASAFYGPFRDAVGSSATLGKSNKSTYQMDPANSDEALREV 246 Query: 249 ALDLQEGADMVMVKPGMPYLDIVRRVKDEFKVPTFAYQVSGEYAMIKAAAQNGWLDHDKA 308 ALDL EGADMVMVKPGMPYLDIVRRVKDEFKVPTFAYQVSGEYAMIKAAAQ GWLDHDK Sbjct: 247 ALDLAEGADMVMVKPGMPYLDIVRRVKDEFKVPTFAYQVSGEYAMIKAAAQQGWLDHDKT 306 Query: 309 MMEAMMAFKRA 319 MMEAM+AFKRA Sbjct: 307 MMEAMIAFKRA 317 >ref|YP_004751095.1| porphobilinogen synthase [Collimonas fungivorans Ter331] gb|AEK60272.1| Porphobilinogen synthase [Collimonas fungivorans Ter331] Length = 398 Score = 540 bits (1390), Expect = e-151, Method: Compositional matrix adjust. Identities = 260/317 (82%), Positives = 285/317 (89%) Query: 3 LTSTSTSAQFPAIRMRRMRKDAFSRAMMQENVITPADLIYPVFIQEGQNLRTPVGSLPGV 62 + + +AQFPAIRMRRMRKDAFSRAMM+EN IT ADLIYPVFI +G+N R + S+PGV Sbjct: 62 MPHSQKTAQFPAIRMRRMRKDAFSRAMMRENTITTADLIYPVFILDGKNQREKINSMPGV 121 Query: 63 ERLSIDQLLHVAEDTVALGIPVLALFPVIDVALKTPDGIEAINPDGLVPRAVAALKQRFP 122 ERLSID LL+VAE+ VALGIPV+ALFPVI+ +LKTPDGIEA NP GL+PRAV LKQRFP Sbjct: 122 ERLSIDLLLNVAEECVALGIPVIALFPVINPSLKTPDGIEATNPQGLIPRAVRELKQRFP 181 Query: 123 ELGILTDVALDPYTSHGQDGVMDDNGYVLNDETTALLVRQALAQAQAGVDIVAPSDMMDG 182 ELGILTDVALDPYTSHGQDGV++ +GYVLNDET A+LV+QAL QA AGVDIVAPSDMMDG Sbjct: 182 ELGILTDVALDPYTSHGQDGVLNADGYVLNDETCAILVKQALTQADAGVDIVAPSDMMDG 241 Query: 183 RIGAVRDALEAEKFIYTRIMAYSAKYASAFYGPFRDAVGSAANLGKGSKSTYQMDPANSD 242 RIGA+R ALE IYTRIMAYSAKYASAFYGPFRDAVGS+A LGK +K+TYQMDPANS+ Sbjct: 242 RIGAIRHALETHHHIYTRIMAYSAKYASAFYGPFRDAVGSSATLGKSNKNTYQMDPANSN 301 Query: 243 EALREVALDLQEGADMVMVKPGMPYLDIVRRVKDEFKVPTFAYQVSGEYAMIKAAAQNGW 302 EAL EVALDL EGADMVMVKPGMPYLDIVRRVKDEFKVPTFAYQVSGEYAMIKAAAQNGW Sbjct: 302 EALHEVALDLAEGADMVMVKPGMPYLDIVRRVKDEFKVPTFAYQVSGEYAMIKAAAQNGW 361 Query: 303 LDHDKAMMEAMMAFKRA 319 LDHDK MMEAM+AFKRA Sbjct: 362 LDHDKTMMEAMLAFKRA 378 >ref|ZP_08274537.1| Porphobilinogen synthase [Oxalobacteraceae bacterium IMCC9480] gb|EGF31998.1| Porphobilinogen synthase [Oxalobacteraceae bacterium IMCC9480] Length = 320 Score = 521 bits (1342), Expect = e-146, Method: Compositional matrix adjust. Identities = 252/300 (84%), Positives = 273/300 (91%) Query: 20 MRKDAFSRAMMQENVITPADLIYPVFIQEGQNLRTPVGSLPGVERLSIDQLLHVAEDTVA 79 MRKDAFSRAMM+ENV+TPADLIYPVFIQEG+N R V S+PGVERLSID+LL VAE+ VA Sbjct: 1 MRKDAFSRAMMRENVLTPADLIYPVFIQEGRNQREKVASMPGVERLSIDELLGVAEECVA 60 Query: 80 LGIPVLALFPVIDVALKTPDGIEAINPDGLVPRAVAALKQRFPELGILTDVALDPYTSHG 139 LGIPV+ALFPVI ALKTPDGIEA NPDGL+PRAV LK+R+PELGI+TD ALDPYTSHG Sbjct: 61 LGIPVMALFPVIGNALKTPDGIEATNPDGLIPRAVRELKKRYPELGIMTDAALDPYTSHG 120 Query: 140 QDGVMDDNGYVLNDETTALLVRQALAQAQAGVDIVAPSDMMDGRIGAVRDALEAEKFIYT 199 QDGV++ GYVLNDET LLV+QAL QA AGVDIVAPSDMMDGRIGA+R ALEA FI+T Sbjct: 121 QDGVINAAGYVLNDETCDLLVKQALTQAAAGVDIVAPSDMMDGRIGAIRHALEANHFIHT 180 Query: 200 RIMAYSAKYASAFYGPFRDAVGSAANLGKGSKSTYQMDPANSDEALREVALDLQEGADMV 259 RIMAYSAKYASAFYGPFRDAVGSA NLGK K+TYQ+DPANSDEALREV LDL EGADMV Sbjct: 181 RIMAYSAKYASAFYGPFRDAVGSAVNLGKSDKATYQIDPANSDEALREVGLDLAEGADMV 240 Query: 260 MVKPGMPYLDIVRRVKDEFKVPTFAYQVSGEYAMIKAAAQNGWLDHDKAMMEAMMAFKRA 319 MVKPGMPYLDIVRRVKDEFKVPTFAYQVSGEYAM+KAAAQNGWLDHDK MME+M+AFKRA Sbjct: 241 MVKPGMPYLDIVRRVKDEFKVPTFAYQVSGEYAMLKAAAQNGWLDHDKVMMESMIAFKRA 300