BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0034.0055.p (353 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_001166072.1| 4-hydroxy-2-ketovalerate aldolase [Novosphin... 527 e-147 ref|YP_004538226.1| 4-hydroxy 2-oxovalerate aldolase [Novosphing... 521 e-146 ref|YP_718030.1| 4-hydroxy-2-ketovalerate aldolase [Sphingomonas... 511 e-143 ref|YP_004555590.1| 4-hydroxy-2-oxovalerate aldolase [Sphingobiu... 508 e-142 ref|YP_728714.1| 4-hydroxy-2-ketovalerate aldolase [Ralstonia eu... 507 e-141 >ref|YP_001166072.1| 4-hydroxy-2-ketovalerate aldolase [Novosphingobium aromaticivorans DSM 12444] sp|A4XF35.1|HOA1_NOVAD RecName: Full=4-hydroxy-2-oxovalerate aldolase 1; Short=HOA 1; AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase 1; AltName: Full=4-hydroxy-2-oxopentanoate aldolase 1 gb|ABP64546.1| pyruvate carboxyltransferase [Novosphingobium aromaticivorans DSM 12444] Length = 346 Score = 527 bits (1357), Expect = e-147, Method: Compositional matrix adjust. Identities = 251/336 (74%), Positives = 287/336 (85%) Query: 1 MNTKTSSSLYIQDVTLRDGMHAIGHSYTVEQVRKIASALDAAGVAAIEVAHGDGLAGSSF 60 N + LYIQDVTLRDGMHA+ H Y ++ VR IASALD AGV AIEVAHGDGL+G+SF Sbjct: 5 FNVEAGDKLYIQDVTLRDGMHAVRHMYGIDHVRSIASALDKAGVDAIEVAHGDGLSGASF 64 Query: 61 NYGFGKHSDREWISAVADVVTKARLTTLLIPGIGTLHDLKDAAAAGVSSVRVATHCTEAD 120 NYGFG H+D EW+ AVADV+ K+ LTTL++PG+GT+ +L+ A GV SVRVATHCTEAD Sbjct: 65 NYGFGAHTDWEWLEAVADVLEKSVLTTLILPGVGTVEELRRAYDIGVRSVRVATHCTEAD 124 Query: 121 IARQHIGAARDLGLDTVGFLMMSHMISPEQLAEQAKLMESYGAECVYVVDSGGALGMSDV 180 +++QHIG ARDLG+D GFLMMSHMI PE LA+QA LMESYGA+CVYV DSGGAL M V Sbjct: 125 VSKQHIGIARDLGMDVSGFLMMSHMIEPEALAQQASLMESYGAQCVYVTDSGGALDMDGV 184 Query: 181 TARFQAFDLVLKPETQRGIHAHHNLSLGVANSIVAVEAGATRVDASLAGMGAGAGNAPLE 240 AR +A+D VLKPETQRGIHAHHNL+LGVANSIVA + GA R+DASL GMGAGAGNAPLE Sbjct: 185 KARLEAYDRVLKPETQRGIHAHHNLALGVANSIVAAQCGAVRIDASLTGMGAGAGNAPLE 244 Query: 241 VFVAAADRLNWHHACDLYALMDAAEDIVRPLQDRPVRVDRETLSLGYAGVYSSFLRHAER 300 VF+AAADR W+H CD+ LMDAAED+VRPLQDRPVRVDRETL+LGYAGVYSSFLRHAE+ Sbjct: 245 VFIAAADRKGWNHGCDVMMLMDAAEDLVRPLQDRPVRVDRETLALGYAGVYSSFLRHAEK 304 Query: 301 AAAAYGLDTRAILIELGRRRMVGGQEDMIVDVALDL 336 AA YGLDTR IL+ELGRR+MVGGQEDMIVDVALD+ Sbjct: 305 AAETYGLDTRTILVELGRRKMVGGQEDMIVDVALDM 340 >ref|YP_004538226.1| 4-hydroxy 2-oxovalerate aldolase [Novosphingobium sp. PP1Y] emb|CCA90259.1| 4-hydroxy 2-oxovalerate aldolase [Novosphingobium sp. PP1Y] Length = 346 Score = 521 bits (1342), Expect = e-146, Method: Compositional matrix adjust. Identities = 248/336 (73%), Positives = 286/336 (85%) Query: 1 MNTKTSSSLYIQDVTLRDGMHAIGHSYTVEQVRKIASALDAAGVAAIEVAHGDGLAGSSF 60 N + LYIQDVTLRDGMHAI H Y ++ VR IASA++ +GV AIEVAHGDGL+G+SF Sbjct: 5 FNVEAGEKLYIQDVTLRDGMHAIRHMYGIDHVRDIASAIEKSGVDAIEVAHGDGLSGASF 64 Query: 61 NYGFGKHSDREWISAVADVVTKARLTTLLIPGIGTLHDLKDAAAAGVSSVRVATHCTEAD 120 NYGFG H+D EW+ AVADV+ K LTTL++PG+GT+ +L+ A GV SVRVATHCTEAD Sbjct: 65 NYGFGAHTDWEWLEAVADVLDKCVLTTLILPGVGTVEELRRAYDIGVRSVRVATHCTEAD 124 Query: 121 IARQHIGAARDLGLDTVGFLMMSHMISPEQLAEQAKLMESYGAECVYVVDSGGALGMSDV 180 +++QHIG ARDLG+D GFLMMSHMI PE LA+QA LMESYGA+CVYV DSGGAL M V Sbjct: 125 VSKQHIGIARDLGMDVSGFLMMSHMIEPEVLAQQALLMESYGAQCVYVTDSGGALDMDGV 184 Query: 181 TARFQAFDLVLKPETQRGIHAHHNLSLGVANSIVAVEAGATRVDASLAGMGAGAGNAPLE 240 ARF+A+D VLKPETQRG+HAHHNL LGVANSIVA + GA R+DASL GMGAGAGNAPLE Sbjct: 185 RARFEAYDRVLKPETQRGMHAHHNLGLGVANSIVAAQCGAVRIDASLTGMGAGAGNAPLE 244 Query: 241 VFVAAADRLNWHHACDLYALMDAAEDIVRPLQDRPVRVDRETLSLGYAGVYSSFLRHAER 300 VF+AA DR W+H CD+ LMDAAED+VRPLQDRPVRVDRETLSLGYAGVYSSFLRHAE+ Sbjct: 245 VFIAAVDRKGWNHGCDVNLLMDAAEDLVRPLQDRPVRVDRETLSLGYAGVYSSFLRHAEK 304 Query: 301 AAAAYGLDTRAILIELGRRRMVGGQEDMIVDVALDL 336 A+ YG+DTRAIL+ELGRR+MVGGQEDMIVDVALD+ Sbjct: 305 ASETYGIDTRAILVELGRRKMVGGQEDMIVDVALDM 340 >ref|YP_718030.1| 4-hydroxy-2-ketovalerate aldolase [Sphingomonas sp. KA1] dbj|BAF03318.1| 4-hydroxy-2-oxovalerate aldolase [Sphingomonas sp. KA1] Length = 342 Score = 511 bits (1316), Expect = e-143, Method: Compositional matrix adjust. Identities = 258/332 (77%), Positives = 287/332 (86%) Query: 5 TSSSLYIQDVTLRDGMHAIGHSYTVEQVRKIASALDAAGVAAIEVAHGDGLAGSSFNYGF 64 T++ LYIQDVTLRDGMHAI H Y +E VR+IA ALD A V AIEVAHGDGL GSSFNYGF Sbjct: 6 TTTKLYIQDVTLRDGMHAIRHQYGIEHVRQIAKALDEAKVDAIEVAHGDGLNGSSFNYGF 65 Query: 65 GKHSDREWISAVADVVTKARLTTLLIPGIGTLHDLKDAAAAGVSSVRVATHCTEADIARQ 124 G H+D EWI AVADVV A+LTTLL+PGIGT+ +LK A A GV SVR+ATHCTEADI++Q Sbjct: 66 GAHTDWEWIEAVADVVKHAKLTTLLLPGIGTIEELKHAYALGVRSVRIATHCTEADISKQ 125 Query: 125 HIGAARDLGLDTVGFLMMSHMISPEQLAEQAKLMESYGAECVYVVDSGGALGMSDVTARF 184 HI AARDLG+DTVGFLMMSHMI P+QLA+QAKLMESYGA CVYV DSGGAL M R Sbjct: 126 HIQAARDLGMDTVGFLMMSHMIEPDQLAQQAKLMESYGATCVYVTDSGGALDMDGYRERL 185 Query: 185 QAFDLVLKPETQRGIHAHHNLSLGVANSIVAVEAGATRVDASLAGMGAGAGNAPLEVFVA 244 A+D VL PET+RGIHAHHNLSLGVANSIV + GA R+DASLAGMGAGAGNAPLEVF+A Sbjct: 186 LAYDRVLDPETERGIHAHHNLSLGVANSIVGAQHGAIRIDASLAGMGAGAGNAPLEVFIA 245 Query: 245 AADRLNWHHACDLYALMDAAEDIVRPLQDRPVRVDRETLSLGYAGVYSSFLRHAERAAAA 304 AA+R WHH CDLY LMDAAE++VRPLQDRPVRVDRETLSLG+AGVYSSFLRHAE+A+ Sbjct: 246 AAERKGWHHGCDLYKLMDAAEELVRPLQDRPVRVDRETLSLGFAGVYSSFLRHAEKASRD 305 Query: 305 YGLDTRAILIELGRRRMVGGQEDMIVDVALDL 336 YG+DTR IL+ELGRRRMVGGQEDMIVDVALD+ Sbjct: 306 YGVDTREILVELGRRRMVGGQEDMIVDVALDM 337 >ref|YP_004555590.1| 4-hydroxy-2-oxovalerate aldolase [Sphingobium chlorophenolicum L-1] gb|AEG51084.1| 4-hydroxy-2-oxovalerate aldolase [Sphingobium chlorophenolicum L-1] Length = 378 Score = 508 bits (1307), Expect = e-142, Method: Compositional matrix adjust. Identities = 255/333 (76%), Positives = 289/333 (86%) Query: 4 KTSSSLYIQDVTLRDGMHAIGHSYTVEQVRKIASALDAAGVAAIEVAHGDGLAGSSFNYG 63 T + LYIQDVTLRDGMHAI H Y ++ V++IA ALD A V AIEVAHGDGL+GSSFNYG Sbjct: 5 PTRTKLYIQDVTLRDGMHAIRHQYGIDHVKRIAKALDDAKVDAIEVAHGDGLSGSSFNYG 64 Query: 64 FGKHSDREWISAVADVVTKARLTTLLIPGIGTLHDLKDAAAAGVSSVRVATHCTEADIAR 123 FG H+D EWI+AVA+V+ + LTTLL+PGIGT+HDLK A GV SVR+ATHCTEAD+++ Sbjct: 65 FGAHTDSEWIAAVAEVLEHSVLTTLLLPGIGTVHDLKHAHDLGVRSVRIATHCTEADVSK 124 Query: 124 QHIGAARDLGLDTVGFLMMSHMISPEQLAEQAKLMESYGAECVYVVDSGGALGMSDVTAR 183 QHI AAR+LG+D GFLMMSHM PE LA QAKLME YGA CVYV DSGGAL M + AR Sbjct: 125 QHIEAARNLGMDVSGFLMMSHMTDPESLARQAKLMEDYGAHCVYVTDSGGALNMEEYAAR 184 Query: 184 FQAFDLVLKPETQRGIHAHHNLSLGVANSIVAVEAGATRVDASLAGMGAGAGNAPLEVFV 243 QA+D VLKPETQRG+HAHHNLSLGVANSIVAV+ GA R+DASLAGMGAGAGNAPLEVF+ Sbjct: 185 LQAYDRVLKPETQRGVHAHHNLSLGVANSIVAVQNGAVRIDASLAGMGAGAGNAPLEVFI 244 Query: 244 AAADRLNWHHACDLYALMDAAEDIVRPLQDRPVRVDRETLSLGYAGVYSSFLRHAERAAA 303 AAADR W+H CDLYALMDAAE++VRPLQDRPVRVDRETL+LGYAGVYSSFLRHAE+AA Sbjct: 245 AAADRYGWNHGCDLYALMDAAEEMVRPLQDRPVRVDRETLTLGYAGVYSSFLRHAEKAAL 304 Query: 304 AYGLDTRAILIELGRRRMVGGQEDMIVDVALDL 336 +GLDTRAIL+E+GRR+MVGGQEDMIVDVALDL Sbjct: 305 DHGLDTRAILVEVGRRKMVGGQEDMIVDVALDL 337 >ref|YP_728714.1| 4-hydroxy-2-ketovalerate aldolase [Ralstonia eutropha H16] sp|Q0K3S5.1|HOA2_RALEH RecName: Full=4-hydroxy-2-oxovalerate aldolase 2; Short=HOA 2; AltName: Full=4-hydroxy-2-keto-pentanoic acid aldolase 2; AltName: Full=4-hydroxy-2-oxopentanoate aldolase 2 emb|CAJ95349.1| 4-Hydroxy-2-oxovalerate aldolase [Ralstonia eutropha H16] Length = 354 Score = 507 bits (1306), Expect = e-141, Method: Compositional matrix adjust. Identities = 259/336 (77%), Positives = 289/336 (86%) Query: 1 MNTKTSSSLYIQDVTLRDGMHAIGHSYTVEQVRKIASALDAAGVAAIEVAHGDGLAGSSF 60 M + + LYI DVTLRDG HAI H Y++E VR+IA+ALDAA V +IEVAHGDGL+GSSF Sbjct: 1 MTAQPTKKLYISDVTLRDGSHAIRHQYSLEHVRRIAAALDAARVDSIEVAHGDGLSGSSF 60 Query: 61 NYGFGKHSDREWISAVADVVTKARLTTLLIPGIGTLHDLKDAAAAGVSSVRVATHCTEAD 120 NYGFG H+D EWI+AVA+ V AR+ TLL+PG+GTLHDL+ A AG VRVATHCTEAD Sbjct: 61 NYGFGAHTDLEWIAAVAETVRHARVATLLLPGVGTLHDLRAAYDAGARVVRVATHCTEAD 120 Query: 121 IARQHIGAARDLGLDTVGFLMMSHMISPEQLAEQAKLMESYGAECVYVVDSGGALGMSDV 180 ++RQHI AR+LG+DTVGFLMMSHM +P LA+QAKLMESYGA+CVYVVDSGGALGM DV Sbjct: 121 VSRQHIEYARELGMDTVGFLMMSHMTTPAALAQQAKLMESYGAQCVYVVDSGGALGMQDV 180 Query: 181 TARFQAFDLVLKPETQRGIHAHHNLSLGVANSIVAVEAGATRVDASLAGMGAGAGNAPLE 240 RF+AF VL+PETQ G+HAHHNLSLGVANSIVAVE G RVDASLAGMGAGAGNAPLE Sbjct: 181 RERFRAFKDVLRPETQTGMHAHHNLSLGVANSIVAVEEGCDRVDASLAGMGAGAGNAPLE 240 Query: 241 VFVAAADRLNWHHACDLYALMDAAEDIVRPLQDRPVRVDRETLSLGYAGVYSSFLRHAER 300 VF+AAA+RL W H CDLY LMDAA+DIVRPLQDRPVRVDRETL+LGYAGVYSSFLRHAE Sbjct: 241 VFIAAAERLGWQHGCDLYTLMDAADDIVRPLQDRPVRVDRETLALGYAGVYSSFLRHAEA 300 Query: 301 AAAAYGLDTRAILIELGRRRMVGGQEDMIVDVALDL 336 AAA YGL T IL+ELGRRRMVGGQEDMIVDVALDL Sbjct: 301 AAARYGLGTVDILVELGRRRMVGGQEDMIVDVALDL 336