BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0034.0054.p (319 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_001566649.1| NAD-binding D-isomer specific 2-hydroxyacid ... 392 e-107 ref|YP_004486349.1| hydroxypyruvate reductase [Delftia sp. Cs1-4... 391 e-107 ref|YP_003775893.1| D-isomer specific 2-hydroxyacid dehydrogenas... 354 9e-96 ref|YP_001342133.1| D-isomer specific 2-hydroxyacid dehydrogenas... 349 3e-94 ref|NP_396409.2| 2-hydroxyacid dehydrogenase [Agrobacterium tume... 338 7e-91 >ref|YP_001566649.1| NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase [Delftia acidovorans SPH-1] gb|ABX38264.1| D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding [Delftia acidovorans SPH-1] Length = 323 Score = 392 bits (1006), Expect = e-107, Method: Compositional matrix adjust. Identities = 190/311 (61%), Positives = 232/311 (74%) Query: 9 PIAFISQADHALSTLWIKELQLAMPEEKILAFSDMSAIEREQCRVAIVANPDPAELSTLP 68 P+ F+ + + W++ LQ A+PEE+++A + A +R C VAIVANP PA+L TLP Sbjct: 13 PLPFVCAPGYPAAQAWLQALQAALPEERVVALDTLDADQRAACEVAIVANPQPADLRTLP 72 Query: 69 RLEWIHSVWAGVERLMADLGDTKLKIVRLVDPQLATTMAEAVLAWTLYLHRQMPLYKQQQ 128 RL+W+HSVWAGVERL+ADLGDT L+IVRLVDPQLA TMAEAVLAWTLYLHR MP Y +QQ Sbjct: 73 RLQWVHSVWAGVERLVADLGDTDLRIVRLVDPQLADTMAEAVLAWTLYLHRDMPRYARQQ 132 Query: 129 KLRLWKAQEYITPAKKTVSILGLGALGEAAAKCLISAGFKLCGWSRNPKQIKNVQCFSGN 188 R W A + + +TVS+LGLGALG+AAA+ L+SAGF++ GWSR P+ + VQC +G+ Sbjct: 133 AARQWLAHDGVRAQDRTVSLLGLGALGKAAAQRLLSAGFQVRGWSRTPRHMDGVQCHAGD 192 Query: 189 DGLKEMLAQTNILICLLPLTPETRYLLDAEKISMLPAGAELINFARGAIIRDLDLRAALD 248 L MLAQT+IL+CLLPLTP+TR L+ A+ ++ LPA A LINFARG I+ D LRAALD Sbjct: 193 AELPAMLAQTDILVCLLPLTPQTRGLVGAQALAALPAHASLINFARGPIVDDAALRAALD 252 Query: 249 STHLNHAVLDVFEVEPLPPNEWHWDHPRVTVLPHCSAPTNRNTASAIVAKNIENYRLSGA 308 L HAVLDVFE EPLP W W HP VTVLPH SAPT+R TASAIVA NI +R SG Sbjct: 253 GGRLAHAVLDVFEQEPLPEASWQWAHPAVTVLPHISAPTDRATASAIVAGNIRRWRASGE 312 Query: 309 IPAHVDTRRGY 319 +P VD RGY Sbjct: 313 LPQAVDAARGY 323 >ref|YP_004486349.1| hydroxypyruvate reductase [Delftia sp. Cs1-4] gb|AEF87994.1| Hydroxypyruvate reductase [Delftia sp. Cs1-4] Length = 320 Score = 391 bits (1004), Expect = e-107, Method: Compositional matrix adjust. Identities = 189/308 (61%), Positives = 233/308 (75%) Query: 12 FISQADHALSTLWIKELQLAMPEEKILAFSDMSAIEREQCRVAIVANPDPAELSTLPRLE 71 F+ + + W++ LQ A+PEE+++A + A +R C VAIVANP PA+L TLPRL+ Sbjct: 13 FVCAPGYPAAQAWLQALQAALPEERVVALDTLDADQRAACEVAIVANPQPADLRTLPRLQ 72 Query: 72 WIHSVWAGVERLMADLGDTKLKIVRLVDPQLATTMAEAVLAWTLYLHRQMPLYKQQQKLR 131 W+HSVWAGVERL+ADLGDT L+IVRLVDPQLA TMAEAVLAWTLYLHR MP Y +QQ R Sbjct: 73 WVHSVWAGVERLVADLGDTDLRIVRLVDPQLAATMAEAVLAWTLYLHRDMPRYARQQAAR 132 Query: 132 LWKAQEYITPAKKTVSILGLGALGEAAAKCLISAGFKLCGWSRNPKQIKNVQCFSGNDGL 191 W A + + +TVS+LGLGALG+AAA+ L+SAGF++ GWSR P+ +++VQC +G+ L Sbjct: 133 QWLAHDGVRAQDRTVSLLGLGALGKAAAQRLLSAGFQVRGWSRTPRHMESVQCHAGDAEL 192 Query: 192 KEMLAQTNILICLLPLTPETRYLLDAEKISMLPAGAELINFARGAIIRDLDLRAALDSTH 251 MLAQT+IL+CLLPLTP+TR ++ A+ ++ LPA A LINFARG I+ D LRAALDS Sbjct: 193 PAMLAQTDILVCLLPLTPQTRGIVGAQALAALPAHASLINFARGPIVDDAALRAALDSGR 252 Query: 252 LNHAVLDVFEVEPLPPNEWHWDHPRVTVLPHCSAPTNRNTASAIVAKNIENYRLSGAIPA 311 L HAVLDVFE EPLP W W HP VTVLPH SAPT+R TASAIVA NI +R SG +P Sbjct: 253 LAHAVLDVFEQEPLPEASWQWAHPAVTVLPHISAPTDRATASAIVAGNIRRWRASGELPQ 312 Query: 312 HVDTRRGY 319 VD RGY Sbjct: 313 AVDAARGY 320 >ref|YP_003775893.1| D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein [Herbaspirillum seropedicae SmR1] gb|ADJ63985.1| D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein [Herbaspirillum seropedicae SmR1] Length = 319 Score = 354 bits (909), Expect = 9e-96, Method: Compositional matrix adjust. Identities = 198/312 (63%), Positives = 235/312 (75%) Query: 8 DPIAFISQADHALSTLWIKELQLAMPEEKILAFSDMSAIEREQCRVAIVANPDPAELSTL 67 PIAF+SQA + WI LQ AMPEE+IL + A + QCRVAIVANPDPA+L + Sbjct: 8 SPIAFVSQAGASEVQQWISALQAAMPEERILPCEQLDADQLAQCRVAIVANPDPAQLKRM 67 Query: 68 PRLEWIHSVWAGVERLMADLGDTKLKIVRLVDPQLATTMAEAVLAWTLYLHRQMPLYKQQ 127 P L W+HSVWAGVERL+ADLG + L++ RLVDP+LA TMAEAVLAWTLYLHR MPLY ++ Sbjct: 68 PNLLWVHSVWAGVERLVADLGQSDLQLTRLVDPRLAATMAEAVLAWTLYLHRDMPLYARR 127 Query: 128 QKLRLWKAQEYITPAKKTVSILGLGALGEAAAKCLISAGFKLCGWSRNPKQIKNVQCFSG 187 Q+ W+AQ Y+ P ++ VS+LGLGALGEAAA L A F + GWSR+ ++ + VQ F G Sbjct: 128 QREHHWEAQPYVLPEQRRVSLLGLGALGEAAAAALRQARFAVNGWSRSAREAEGVQTFHG 187 Query: 188 NDGLKEMLAQTNILICLLPLTPETRYLLDAEKISMLPAGAELINFARGAIIRDLDLRAAL 247 GL +MLAQT+IL+CLLPLT ETR L+DA ++MLP A+LINFARG II D L+AAL Sbjct: 188 PAGLAQMLAQTDILVCLLPLTAETRGLIDAAHLAMLPPQAQLINFARGPIIDDAALKAAL 247 Query: 248 DSTHLNHAVLDVFEVEPLPPNEWHWDHPRVTVLPHCSAPTNRNTASAIVAKNIENYRLSG 307 D+ L HAVLDVF VEPLPP W W HP VTVLPHCSAPT+R TASAIVA NI YR SG Sbjct: 248 DAGQLRHAVLDVFAVEPLPPAAWPWSHPAVTVLPHCSAPTDRQTASAIVAANIRRYRHSG 307 Query: 308 AIPAHVDTRRGY 319 I A+VD RRGY Sbjct: 308 EIAANVDLRRGY 319 >ref|YP_001342133.1| D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein subunit [Marinomonas sp. MWYL1] gb|ABR72198.1| D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding [Marinomonas sp. MWYL1] Length = 311 Score = 349 bits (896), Expect = 3e-94, Method: Compositional matrix adjust. Identities = 169/310 (54%), Positives = 219/310 (70%) Query: 10 IAFISQADHALSTLWIKELQLAMPEEKILAFSDMSAIEREQCRVAIVANPDPAELSTLPR 69 I F+S+AD A +WIK L AMP E I F D++A +++QC +AIVANPDP +L +LP Sbjct: 2 IPFVSRADSAEQKIWIKHLSSAMPNEVIAPFVDLTAEQKQQCDIAIVANPDPQDLLSLPS 61 Query: 70 LEWIHSVWAGVERLMADLGDTKLKIVRLVDPQLATTMAEAVLAWTLYLHRQMPLYKQQQK 129 L+W+HSVWAGVER++ +L IVRLVD LA TM+EAVLAWTL+LHR MP+Y +QQ Sbjct: 62 LKWVHSVWAGVERMINELSSPSFSIVRLVDSNLAETMSEAVLAWTLFLHRDMPIYAKQQA 121 Query: 130 LRLWKAQEYITPAKKTVSILGLGALGEAAAKCLISAGFKLCGWSRNPKQIKNVQCFSGND 189 + W + + + +LGLG LG +A+ L++ GF + GWSRNPKQ++ V+CF G + Sbjct: 122 KQSWVQLPMVAAKDRRIGVLGLGELGRVSAQRLVANGFSVAGWSRNPKQVEGVECFHGEE 181 Query: 190 GLKEMLAQTNILICLLPLTPETRYLLDAEKISMLPAGAELINFARGAIIRDLDLRAALDS 249 GL +L+Q++IL+CLLPLT ETR LL+ + +S LP GA LINFARG II D L L+ Sbjct: 182 GLIPLLSQSDILVCLLPLTIETRGLLNHQNLSCLPVGASLINFARGLIIDDEALLVKLER 241 Query: 250 THLNHAVLDVFEVEPLPPNEWHWDHPRVTVLPHCSAPTNRNTASAIVAKNIENYRLSGAI 309 L+HAVLDVF EPLP N W H +TVLPH SAPT+ +AS IVAKNI+ YRL+G+I Sbjct: 242 GDLSHAVLDVFVNEPLPENHSFWLHESITVLPHISAPTHPVSASEIVAKNIKQYRLTGSI 301 Query: 310 PAHVDTRRGY 319 P VD RGY Sbjct: 302 PPSVDLLRGY 311 >ref|NP_396409.2| 2-hydroxyacid dehydrogenase [Agrobacterium tumefaciens str. C58] gb|AAK90850.2| 2-hydroxyacid dehydrogenase [Agrobacterium tumefaciens str. C58] Length = 311 Score = 338 bits (867), Expect = 7e-91, Method: Compositional matrix adjust. Identities = 175/310 (56%), Positives = 220/310 (70%) Query: 10 IAFISQADHALSTLWIKELQLAMPEEKILAFSDMSAIEREQCRVAIVANPDPAELSTLPR 69 I +++ LW+ L MP E I+ F + RE+ +AIVANPDPA+++ LP Sbjct: 2 IVLVTRMSEDAERLWLTSLSRKMPGETIVPFRQLDEAAREKADIAIVANPDPADIARLPN 61 Query: 70 LEWIHSVWAGVERLMADLGDTKLKIVRLVDPQLATTMAEAVLAWTLYLHRQMPLYKQQQK 129 L+WIHSVWAGVERL+A+LG+++L IVRLVDPQL+ TMAEAVLAWT YL R MP Y Q+ Sbjct: 62 LKWIHSVWAGVERLVAELGESRLPIVRLVDPQLSQTMAEAVLAWTYYLFRDMPAYANFQR 121 Query: 130 LRLWKAQEYITPAKKTVSILGLGALGEAAAKCLISAGFKLCGWSRNPKQIKNVQCFSGND 189 R+W+ Y P T+ +LGLGALG +A L AGF + GWSR+ K+I VQ F G+ Sbjct: 122 QRVWQQLAYRRPQDVTIGLLGLGALGAESAARLRYAGFNVIGWSRSHKEIDGVQTFHGDR 181 Query: 190 GLKEMLAQTNILICLLPLTPETRYLLDAEKISMLPAGAELINFARGAIIRDLDLRAALDS 249 GL+E+L ++ IL+CLLPLT ETR L+DA ++S+LP GA LINFARG I+ DL ALDS Sbjct: 182 GLEELLGRSEILVCLLPLTDETRGLIDAVRLSLLPEGASLINFARGPIVVADDLIRALDS 241 Query: 250 THLNHAVLDVFEVEPLPPNEWHWDHPRVTVLPHCSAPTNRNTASAIVAKNIENYRLSGAI 309 + HAVLDVF+VEPLPP+ WDHP +TVLPH SAPT+R TA+AIVA NI YR SGA+ Sbjct: 242 GAMKHAVLDVFDVEPLPPDNKLWDHPAITVLPHISAPTDRETAAAIVAGNILTYRSSGAL 301 Query: 310 PAHVDTRRGY 319 P VD RGY Sbjct: 302 PPTVDLARGY 311