BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0029.0003.p (558 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003778167.1| methylmalonate-semialdehyde dehydrogenase [H... 897 0.0 ref|YP_004755057.1| methylmalonate-semialdehyde dehydrogenase [C... 876 0.0 ref|YP_001355332.1| methylmalonate-semialdehyde dehydrogenase [J... 847 0.0 ref|YP_001101643.1| methylmalonate-semialdehyde dehydrogenase, o... 843 0.0 ref|YP_004750751.1| methylmalonate-semialdehyde dehydrogenase [C... 807 0.0 >ref|YP_003778167.1| methylmalonate-semialdehyde dehydrogenase [Herbaspirillum seropedicae SmR1] gb|ADJ66259.1| methylmalonate-semialdehyde dehydrogenase protein [Herbaspirillum seropedicae SmR1] Length = 503 Score = 897 bits (2317), Expect = 0.0, Method: Compositional matrix adjust. Identities = 447/498 (89%), Positives = 474/498 (95%) Query: 61 IQHYINGRIAPSESGRQQDVFNPATGEVSRQVVLASTAEVNAAVASASAAAPGWAETAPL 120 I H+ING+I+ SESGR QDVFNPATG + +V LAS EVNAAVA+ASAAAP WAETAPL Sbjct: 6 IDHFINGQISRSESGRSQDVFNPATGAATAKVALASVQEVNAAVAAASAAAPAWAETAPL 65 Query: 121 KRARVLFKFKELIEQHHDDLAAAITREHGKVFSDAKGEVTRGLEIVEFACGVPQLLKTQF 180 KRARVLFKFKELIEQ+HD LA AIT EHGKVFSDAKGEVTRGLEIVEFA G+PQLLKTQF Sbjct: 66 KRARVLFKFKELIEQNHDALAKAITLEHGKVFSDAKGEVTRGLEIVEFATGIPQLLKTQF 125 Query: 181 TDNIGGGIDNWNLRQPLGVTAGITPFNFPVMVPLWMAPMAIATGNSFILKPSERDPTPSL 240 TDNIGGGIDNWNLRQPLGVTAGITPFNFPVMVPLWMAP+AIATGNSF+LKPSERDP+PSL Sbjct: 126 TDNIGGGIDNWNLRQPLGVTAGITPFNFPVMVPLWMAPIAIATGNSFVLKPSERDPSPSL 185 Query: 241 MLADLFKRAGLPDGVFNVVQGDKVAVDALLQHPDVQAISFVGSTPIAEYIYSEATKRAGT 300 MLA+LFKRAGLPDGVFNVVQGDKVAVDALL+HP+VQA+SFVGSTPIAEYIY +AT+RAGT Sbjct: 186 MLAELFKRAGLPDGVFNVVQGDKVAVDALLEHPEVQAVSFVGSTPIAEYIYRKATERAGT 245 Query: 301 FPLRAQALGGAKNHLVVMPDANLEQAVDALIGAAYGSAGERCMAISVAVAVGSVADKLVE 360 FPLRAQALGGAKNHLVVMPDANL+QAVDALIGAAYGSAGERCMAISVAVAVGSVADKLVE Sbjct: 246 FPLRAQALGGAKNHLVVMPDANLDQAVDALIGAAYGSAGERCMAISVAVAVGSVADKLVE 305 Query: 361 ALIPRVKALKIRNGMEADAEMGPLVTATHKAKVEGYIDDGVKAGAKLLVDGRGITVPGHE 420 ALIPRVKALK++NGME DAEMGPLVTA HKAKVEGYI GV AGAKLLVDGRG+ VPGHE Sbjct: 306 ALIPRVKALKVKNGMEDDAEMGPLVTAAHKAKVEGYIQSGVDAGAKLLVDGRGLKVPGHE 365 Query: 421 NGFFVGGTLFDNVTLDMKIYKEEIFGPVLCVVRVPDFAEAVRLINAHEYGNGVSLFTADG 480 GFF+GGTLFD+VT +MKIY+EEIFGPVLCVVRVPDFA AV+LINAHEYGNGVSLFTADG Sbjct: 366 EGFFIGGTLFDHVTTEMKIYQEEIFGPVLCVVRVPDFASAVQLINAHEYGNGVSLFTADG 425 Query: 481 NTAHEFSRRIQVGMVGINVPIPVPMAWHSFGGWKRSLFGDTHAYGEEGIKFYTRYKSIMQ 540 NTAHEFSRRIQVGMVGINVPIPVPMAWHSFGGWKRSLFGDTHAYGEEGI+FYTRYKSIMQ Sbjct: 426 NTAHEFSRRIQVGMVGINVPIPVPMAWHSFGGWKRSLFGDTHAYGEEGIRFYTRYKSIMQ 485 Query: 541 RWSATIGKGAEFTMPVAK 558 RWSATIGKGAEFTMPVAK Sbjct: 486 RWSATIGKGAEFTMPVAK 503 >ref|YP_004755057.1| methylmalonate-semialdehyde dehydrogenase [Collimonas fungivorans Ter331] gb|AEK64234.1| methylmalonate-semialdehyde dehydrogenase, oxidoreductase protein [Collimonas fungivorans Ter331] Length = 506 Score = 876 bits (2264), Expect = 0.0, Method: Compositional matrix adjust. Identities = 425/506 (83%), Positives = 467/506 (92%), Gaps = 1/506 (0%) Query: 54 MTAAPS-TIQHYINGRIAPSESGRQQDVFNPATGEVSRQVVLASTAEVNAAVASASAAAP 112 MT +P+ IQHYING++A S SGR QDVFNPATG VS +VVL S EVN+AVA+ASAAA Sbjct: 1 MTTSPTPLIQHYINGKVAESTSGRLQDVFNPATGAVSARVVLGSVEEVNSAVAAASAAAS 60 Query: 113 GWAETAPLKRARVLFKFKELIEQHHDDLAAAITREHGKVFSDAKGEVTRGLEIVEFACGV 172 GWA+TAPLKRARV+F+FKEL+EQHHD LAAAITREHGKVFSDAKGEVTRGLEIVEFACGV Sbjct: 61 GWADTAPLKRARVMFRFKELMEQHHDALAAAITREHGKVFSDAKGEVTRGLEIVEFACGV 120 Query: 173 PQLLKTQFTDNIGGGIDNWNLRQPLGVTAGITPFNFPVMVPLWMAPMAIATGNSFILKPS 232 P LLKTQFTDNIGGGIDNWNLRQPLGVTAGITPFNFPVMVPLWMAPMAIATGN+FILKPS Sbjct: 121 PHLLKTQFTDNIGGGIDNWNLRQPLGVTAGITPFNFPVMVPLWMAPMAIATGNTFILKPS 180 Query: 233 ERDPTPSLMLADLFKRAGLPDGVFNVVQGDKVAVDALLQHPDVQAISFVGSTPIAEYIYS 292 ERDP+PSLM+A+LF +AGLPDGVFNVVQGDK+AVD LLQHPDV+A+SFVGSTPIAEYIY Sbjct: 181 ERDPSPSLMMAELFHQAGLPDGVFNVVQGDKLAVDTLLQHPDVKAVSFVGSTPIAEYIYQ 240 Query: 293 EATKRAGTFPLRAQALGGAKNHLVVMPDANLEQAVDALIGAAYGSAGERCMAISVAVAVG 352 E +R G +PLR QALGGAKNHLVVMPDA+L+QAVDAL+GAAYGSAGERCMAISVAVAVG Sbjct: 241 EGARRKGAYPLRVQALGGAKNHLVVMPDADLDQAVDALMGAAYGSAGERCMAISVAVAVG 300 Query: 353 SVADKLVEALIPRVKALKIRNGMEADAEMGPLVTATHKAKVEGYIDDGVKAGAKLLVDGR 412 +VADKL+EALIPRVKALKI+NGMEADAEMGP+V+A HK K+E YI+ GV AGAKLLVDGR Sbjct: 301 NVADKLIEALIPRVKALKIKNGMEADAEMGPVVSAVHKEKIEAYIEGGVAAGAKLLVDGR 360 Query: 413 GITVPGHENGFFVGGTLFDNVTLDMKIYKEEIFGPVLCVVRVPDFAEAVRLINAHEYGNG 472 G+ V G E GFF+GG+LFD VT +MKIY+EEIFGPVLC+VRVPDFA AV LINAHE+GNG Sbjct: 361 GLKVAGLEQGFFLGGSLFDQVTPEMKIYQEEIFGPVLCIVRVPDFAAAVNLINAHEFGNG 420 Query: 473 VSLFTADGNTAHEFSRRIQVGMVGINVPIPVPMAWHSFGGWKRSLFGDTHAYGEEGIKFY 532 V+LFT+DGNTA EFSRRI+VGMVGINVPIPVPMAWHSFGGWKRSLFGDTHAYGEEGI+FY Sbjct: 421 VALFTSDGNTAREFSRRIEVGMVGINVPIPVPMAWHSFGGWKRSLFGDTHAYGEEGIRFY 480 Query: 533 TRYKSIMQRWSATIGKGAEFTMPVAK 558 TRYKSIMQRW TI KGAEFTMPVAK Sbjct: 481 TRYKSIMQRWPQTISKGAEFTMPVAK 506 >ref|YP_001355332.1| methylmalonate-semialdehyde dehydrogenase [Janthinobacterium sp. Marseille] gb|ABR88793.1| methylmalonate-semialdehyde dehydrogenase [Janthinobacterium sp. Marseille] Length = 505 Score = 847 bits (2189), Expect = 0.0, Method: Compositional matrix adjust. Identities = 411/501 (82%), Positives = 463/501 (92%), Gaps = 1/501 (0%) Query: 59 STIQHYINGRIAPSESGRQQDVFNPATGEVSRQVVLASTAEVNAAVASASAAAPGWAETA 118 + I+HYINGR+ + GRQQDVFNPATGE S QVVLAS A+V A VA+A AAAP WA+TA Sbjct: 5 AKIKHYINGRLTETAGGRQQDVFNPATGEASAQVVLASDADVQAVVATAKAAAPAWADTA 64 Query: 119 PLKRARVLFKFKELIEQHHDDLAAAITREHGKVFSDAKGEVTRGLEIVEFACGVPQLLKT 178 PLKRAR+LFKFK+LIE+HHDDLAAAITREHGKVFSDAKGEVTRGLE+VEFACGVPQLLKT Sbjct: 65 PLKRARILFKFKDLIEKHHDDLAAAITREHGKVFSDAKGEVTRGLEVVEFACGVPQLLKT 124 Query: 179 QFTDNIGGGIDNWNLRQPLGVTAGITPFNFPVMVPLWMAPMAIATGNSFILKPSERDPTP 238 QFTDNIGGGIDNWNLRQPLGVTAGITPFNFP MVP+WMAP+A+ATGN+FILKPSERDP+P Sbjct: 125 QFTDNIGGGIDNWNLRQPLGVTAGITPFNFPFMVPMWMAPVALATGNTFILKPSERDPSP 184 Query: 239 SLMLADLFKRAGLPDGVFNVVQGDKVAVDALLQHPDVQAISFVGSTPIAEYIYSE-ATKR 297 SLM+A+L ++AGLPDGVFNV+QGDK+AVD LLQHPDV+A+SFVGSTPIAEYIY+ A ++ Sbjct: 185 SLMVAELLQQAGLPDGVFNVLQGDKLAVDGLLQHPDVKAVSFVGSTPIAEYIYATGAARK 244 Query: 298 AGTFPLRAQALGGAKNHLVVMPDANLEQAVDALIGAAYGSAGERCMAISVAVAVGSVADK 357 G++PLR QALGGAKNHLVVMPDANLEQAVDALIGAAYGSAGERCMAISVAVAVG +ADK Sbjct: 245 GGSYPLRVQALGGAKNHLVVMPDANLEQAVDALIGAAYGSAGERCMAISVAVAVGDIADK 304 Query: 358 LVEALIPRVKALKIRNGMEADAEMGPLVTATHKAKVEGYIDDGVKAGAKLLVDGRGITVP 417 LV ALIPRVK+LK++NGMEADAEMGP+V+A HKAK+EGYID GVKAGAKLLVDGRG+ V Sbjct: 305 LVAALIPRVKSLKVKNGMEADAEMGPVVSAAHKAKIEGYIDAGVKAGAKLLVDGRGLKVA 364 Query: 418 GHENGFFVGGTLFDNVTLDMKIYKEEIFGPVLCVVRVPDFAEAVRLINAHEYGNGVSLFT 477 GH+ GFF+GG LFD+VT +M IY+EEIFGPVLCV+RVP+FA A+ LIN HE+GNGVSLFT Sbjct: 365 GHDKGFFLGGCLFDHVTPEMTIYQEEIFGPVLCVLRVPNFAAALELINRHEFGNGVSLFT 424 Query: 478 ADGNTAHEFSRRIQVGMVGINVPIPVPMAWHSFGGWKRSLFGDTHAYGEEGIKFYTRYKS 537 +DGNTA EFSRR++VGMVGINVPIPVPMAWHSFGGWKRS+FGDTHAYGEEGIKFYTRYKS Sbjct: 425 SDGNTAREFSRRVEVGMVGINVPIPVPMAWHSFGGWKRSMFGDTHAYGEEGIKFYTRYKS 484 Query: 538 IMQRWSATIGKGAEFTMPVAK 558 IMQRW +IGKGAEF MP +K Sbjct: 485 IMQRWPESIGKGAEFAMPTSK 505 >ref|YP_001101643.1| methylmalonate-semialdehyde dehydrogenase, oxidoreductase protein [Herminiimonas arsenicoxydans] emb|CAL63522.1| methylmalonate-semialdehyde dehydrogenase [acylating] (MMSDH) [Herminiimonas arsenicoxydans] Length = 506 Score = 843 bits (2179), Expect = 0.0, Method: Compositional matrix adjust. Identities = 407/506 (80%), Positives = 460/506 (90%) Query: 53 LMTAAPSTIQHYINGRIAPSESGRQQDVFNPATGEVSRQVVLASTAEVNAAVASASAAAP 112 + +A STI+HYING + + G QQ VFNPATGE+S VVLAS A+V AVA+A AAAP Sbjct: 1 MKNSAVSTIEHYINGNLTNTVGGGQQPVFNPATGEISANVVLASDADVQTAVAAAKAAAP 60 Query: 113 GWAETAPLKRARVLFKFKELIEQHHDDLAAAITREHGKVFSDAKGEVTRGLEIVEFACGV 172 WAE APLKRAR+LFKFK+LIE+HH+DLAAAITREHGKVFSDAKGEVTRGLE+VEFACGV Sbjct: 61 AWAEMAPLKRARILFKFKDLIERHHNDLAAAITREHGKVFSDAKGEVTRGLEVVEFACGV 120 Query: 173 PQLLKTQFTDNIGGGIDNWNLRQPLGVTAGITPFNFPVMVPLWMAPMAIATGNSFILKPS 232 PQLLKTQF+DNIGGGIDNWNLRQPLGVTAGITPFNFP MVP+WMAP+A+ATGN+FILKPS Sbjct: 121 PQLLKTQFSDNIGGGIDNWNLRQPLGVTAGITPFNFPFMVPMWMAPVALATGNTFILKPS 180 Query: 233 ERDPTPSLMLADLFKRAGLPDGVFNVVQGDKVAVDALLQHPDVQAISFVGSTPIAEYIYS 292 ERDP+PSLM+A+L +AGLPDGVFNV+QGDK AVD LLQHPD++A+SFVGSTPIAEYIY Sbjct: 181 ERDPSPSLMVAELLHQAGLPDGVFNVLQGDKRAVDGLLQHPDIKAVSFVGSTPIAEYIYQ 240 Query: 293 EATKRAGTFPLRAQALGGAKNHLVVMPDANLEQAVDALIGAAYGSAGERCMAISVAVAVG 352 R G++PLR QALGGAKNHLVVMPDANLEQAVDALIGAAYGSAGERCMAISVAVAVG Sbjct: 241 AGAARKGSYPLRVQALGGAKNHLVVMPDANLEQAVDALIGAAYGSAGERCMAISVAVAVG 300 Query: 353 SVADKLVEALIPRVKALKIRNGMEADAEMGPLVTATHKAKVEGYIDDGVKAGAKLLVDGR 412 SVADKLV ALIPRVK+LK++NGME+DAEMGP+V+A HKAK+EGYI+ G+K+GAKLLVDGR Sbjct: 301 SVADKLVAALIPRVKSLKVKNGMESDAEMGPVVSAAHKAKIEGYIEAGIKSGAKLLVDGR 360 Query: 413 GITVPGHENGFFVGGTLFDNVTLDMKIYKEEIFGPVLCVVRVPDFAEAVRLINAHEYGNG 472 G+TV GH NGFF+GG LFDNVT +M IY+EEIFGPVLCVVRVPDF+ A+ LINAHE+GNG Sbjct: 361 GLTVDGHSNGFFLGGCLFDNVTPEMTIYQEEIFGPVLCVVRVPDFSAALDLINAHEFGNG 420 Query: 473 VSLFTADGNTAHEFSRRIQVGMVGINVPIPVPMAWHSFGGWKRSLFGDTHAYGEEGIKFY 532 V+LFT+DGNTA EFSRR+++GMVGINVPIPVPMAWHSFGGWKRS+FGDTHAYGEEGIKFY Sbjct: 421 VALFTSDGNTAREFSRRVEIGMVGINVPIPVPMAWHSFGGWKRSMFGDTHAYGEEGIKFY 480 Query: 533 TRYKSIMQRWSATIGKGAEFTMPVAK 558 TRYKSIMQRW +I KGAEF MP +K Sbjct: 481 TRYKSIMQRWPESISKGAEFAMPTSK 506 >ref|YP_004750751.1| methylmalonate-semialdehyde dehydrogenase [Collimonas fungivorans Ter331] gb|AEK59928.1| Methylmalonate-semialdehyde dehydrogenase [Collimonas fungivorans Ter331] Length = 499 Score = 807 bits (2084), Expect = 0.0, Method: Compositional matrix adjust. Identities = 391/498 (78%), Positives = 427/498 (85%), Gaps = 4/498 (0%) Query: 61 IQHYINGRIAPSESGRQQDVFNPATGEVSRQVVLASTAEVNAAVASASAAAPGWAETAPL 120 I H+I+G A S R DVFNPATG V QV LAST EV+ VASA AA P WAET+PL Sbjct: 6 INHFISGTQATGRSERYSDVFNPATGAVVAQVALASTQEVDKVVASACAAFPAWAETSPL 65 Query: 121 KRARVLFKFKELIEQHHDDLAAAITREHGKVFSDAKGEVTRGLEIVEFACGVPQLLKTQF 180 +RAR++FKFKEL+EQHHD LAA ITREHGKVFSDAKGEV RG+E+VEFACG+P LLKT Sbjct: 66 RRARIMFKFKELLEQHHDQLAALITREHGKVFSDAKGEVVRGIEVVEFACGIPHLLKTSH 125 Query: 181 TDNIGGGIDNWNLRQPLGVTAGITPFNFPVMVPLWMAPMAIATGNSFILKPSERDPTPSL 240 TDNIGGGIDNWNLRQPLGV AGITPFNFPVMVP+WM P+AIA GN FILKPSERDP+ SL Sbjct: 126 TDNIGGGIDNWNLRQPLGVVAGITPFNFPVMVPMWMFPVAIACGNCFILKPSERDPSASL 185 Query: 241 MLADLFKRAGLPDGVFNVVQGDKVAVDALLQHPDVQAISFVGSTPIAEYIYSEATKRAGT 300 ++ADL K+AGLPDGVFNVVQGDK AVDALL HPDVQA+SFVGSTPIAEYIY+E +R Sbjct: 186 LIADLLKQAGLPDGVFNVVQGDKTAVDALLAHPDVQALSFVGSTPIAEYIYTEGARRGK- 244 Query: 301 FPLRAQALGGAKNHLVVMPDANLEQAVDALIGAAYGSAGERCMAISVAVAVGSVADKLVE 360 R QALGGAKNHLVVMPDA+LEQAVDALIGAAYGSAGERCMAISVAVAVG VAD+LV+ Sbjct: 245 ---RVQALGGAKNHLVVMPDADLEQAVDALIGAAYGSAGERCMAISVAVAVGDVADRLVQ 301 Query: 361 ALIPRVKALKIRNGMEADAEMGPLVTATHKAKVEGYIDDGVKAGAKLLVDGRGITVPGHE 420 L R ALKI NG +AD+EMGPLVT HKAKVE Y+ GV+ GAKLLVDGRGI+V GHE Sbjct: 302 QLAQRAAALKIGNGDQADSEMGPLVTGVHKAKVEAYVAKGVEEGAKLLVDGRGISVAGHE 361 Query: 421 NGFFVGGTLFDNVTLDMKIYKEEIFGPVLCVVRVPDFAEAVRLINAHEYGNGVSLFTADG 480 NGFFVGGTLFD+VT +M IYKEEIFGPVL VVRVPD A AV L+NAHE+GNGVSLFT+DG Sbjct: 362 NGFFVGGTLFDHVTPEMTIYKEEIFGPVLSVVRVPDLASAVELVNAHEFGNGVSLFTSDG 421 Query: 481 NTAHEFSRRIQVGMVGINVPIPVPMAWHSFGGWKRSLFGDTHAYGEEGIKFYTRYKSIMQ 540 A FSR+IQVGMVGINVPIPVPMAWHSFGGWKRSLFGD HAYGEEGI+FYTRYKSIMQ Sbjct: 422 GVARAFSRQIQVGMVGINVPIPVPMAWHSFGGWKRSLFGDHHAYGEEGIRFYTRYKSIMQ 481 Query: 541 RWSATIGKGAEFTMPVAK 558 RW +I KGAEFTMPVAK Sbjct: 482 RWPDSIAKGAEFTMPVAK 499