BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0027.0061.p (297 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003776462.1| 3-hydroxyisobutyrate dehydrogenase [Herbaspi... 498 e-139 ref|ZP_05136769.1| 3-hydroxyisobutyrate dehydrogenase [Stenotrop... 355 4e-96 ref|YP_001970187.1| putative 3-hydroxyisobutyrate dehydrogenase ... 353 2e-95 ref|YP_002026611.1| 3-hydroxyisobutyrate dehydrogenase [Stenotro... 352 3e-95 ref|YP_004790785.1| 3-hydroxyisobutyrate dehydrogenase [Burkhold... 351 1e-94 >ref|YP_003776462.1| 3-hydroxyisobutyrate dehydrogenase [Herbaspirillum seropedicae SmR1] gb|ADJ64554.1| 3-hydroxyisobutyrate dehydrogenase protein [Herbaspirillum seropedicae SmR1] Length = 297 Score = 498 bits (1281), Expect = e-139, Method: Compositional matrix adjust. Identities = 251/297 (84%), Positives = 275/297 (92%) Query: 1 MSADIVFIGLGNMGLPMAQNLVKAGYSVSGHDLVKASVDKLVESGGVTEADAMAAVAKAK 60 MSA+IVFIGLGNMGLPMAQNLVKAG+SVSGHDLVKASVDKLVE GG TEAD+MAAVAKA Sbjct: 1 MSANIVFIGLGNMGLPMAQNLVKAGFSVSGHDLVKASVDKLVEVGGKTEADSMAAVAKAD 60 Query: 61 VVITMLPASKHVESIYLGDKGILANIKPGTLLIDCSTIAPESARMVAAAALEKGYTMLDA 120 VVITMLPAS+HVES+YLG+ G+LA+ KPGTLLIDCSTIAPE+AR VAAAA +G+ MLDA Sbjct: 61 VVITMLPASRHVESLYLGEAGVLASAKPGTLLIDCSTIAPEAARKVAAAAKARGFEMLDA 120 Query: 121 PVSGGTGGATAGTLTFMVGGTDDGFGLAKPYLEKMGKAIYHAGASGSGQTVKVCNNMLLG 180 PVSGGT GATAGTLTFMVGG+ + F A+PYL+KMGKAIYHAG SGSGQTVKVCNNMLLG Sbjct: 121 PVSGGTNGATAGTLTFMVGGSKEAFEAAQPYLQKMGKAIYHAGESGSGQTVKVCNNMLLG 180 Query: 181 ILMIGTSEAIRLGIANGMDPKVLSEVMSKSSGRNWTLEVYNPCPGVMENAPASKGYAGGF 240 ILMIGTSEAIRLG+ANGMDPKVLSE+MSKSSGRNWTLEVYNPCPGVME APASKGYAGGF Sbjct: 181 ILMIGTSEAIRLGMANGMDPKVLSEIMSKSSGRNWTLEVYNPCPGVMETAPASKGYAGGF 240 Query: 241 GVDLMLKDLGLAVENALATGSSVPMGALARNLYDIHSKSGSGGLDFSSVFNMLAKAK 297 GVDLMLKDLGLAVENALAT ++P+GA ARNLYDIHS +G+G LDFSS+FNML KA+ Sbjct: 241 GVDLMLKDLGLAVENALATNCAIPLGATARNLYDIHSMNGAGKLDFSSIFNMLGKAQ 297 >ref|ZP_05136769.1| 3-hydroxyisobutyrate dehydrogenase [Stenotrophomonas sp. SKA14] gb|EED40830.1| 3-hydroxyisobutyrate dehydrogenase [Stenotrophomonas sp. SKA14] Length = 296 Score = 355 bits (912), Expect = 4e-96, Method: Compositional matrix adjust. Identities = 177/293 (60%), Positives = 224/293 (76%) Query: 5 IVFIGLGNMGLPMAQNLVKAGYSVSGHDLVKASVDKLVESGGVTEADAMAAVAKAKVVIT 64 I FIGLGNMG PMA NLVK G+SV DLV A+V V++G + A +A A+VVI+ Sbjct: 4 IAFIGLGNMGGPMAANLVKNGHSVRVFDLVPAAVQAAVDAGASAASTARDTLADAEVVIS 63 Query: 65 MLPASKHVESIYLGDKGILANIKPGTLLIDCSTIAPESARMVAAAALEKGYTMLDAPVSG 124 MLPAS+HVE +YLGD GILA I G L+IDCSTIAP SAR V+ AA +G M+DAPVSG Sbjct: 64 MLPASRHVEGVYLGDDGILAAIPAGALVIDCSTIAPASARKVSEAAAARGLQMIDAPVSG 123 Query: 125 GTGGATAGTLTFMVGGTDDGFGLAKPYLEKMGKAIYHAGASGSGQTVKVCNNMLLGILMI 184 GT GA AGTLTF+VGG +D A+P L+ MGK I+H GASG+GQ K+CNNM LG++M Sbjct: 124 GTAGAQAGTLTFIVGGEEDALERARPVLQAMGKNIFHVGASGAGQVAKLCNNMALGVIMA 183 Query: 185 GTSEAIRLGIANGMDPKVLSEVMSKSSGRNWTLEVYNPCPGVMENAPASKGYAGGFGVDL 244 T EAI LG+A+G+DPKVLS++M+ S+GR+W EV NP PGV+ENAPAS+GY+GGFG DL Sbjct: 184 VTGEAIALGVAHGLDPKVLSQMMAVSTGRSWATEVCNPWPGVLENAPASRGYSGGFGSDL 243 Query: 245 MLKDLGLAVENALATGSSVPMGALARNLYDIHSKSGSGGLDFSSVFNMLAKAK 297 MLKD+GLAVE A++ G+S+P+G +ARNLY ++ ++G G LDFSSV ++ K Sbjct: 244 MLKDMGLAVEAAMSVGASIPLGEVARNLYSMNHQAGRGKLDFSSVVQLITSEK 296 >ref|YP_001970187.1| putative 3-hydroxyisobutyrate dehydrogenase [Stenotrophomonas maltophilia K279a] emb|CAQ43872.1| putative 3-hydroxyisobutyrate dehydrogenase [Stenotrophomonas maltophilia K279a] Length = 296 Score = 353 bits (905), Expect = 2e-95, Method: Compositional matrix adjust. Identities = 177/293 (60%), Positives = 224/293 (76%) Query: 5 IVFIGLGNMGLPMAQNLVKAGYSVSGHDLVKASVDKLVESGGVTEADAMAAVAKAKVVIT 64 I FIGLGNMG PMA NLVK G+SV DLV A+V V++G + A +A A+VVI+ Sbjct: 4 IAFIGLGNMGGPMAANLVKNGHSVRVFDLVPAAVQAAVDAGASAASSARDTLADAEVVIS 63 Query: 65 MLPASKHVESIYLGDKGILANIKPGTLLIDCSTIAPESARMVAAAALEKGYTMLDAPVSG 124 MLPAS+HVE +YLGD GILA I G L+IDCSTIAP SAR V+ AA +G M+DAPVSG Sbjct: 64 MLPASRHVEGVYLGDDGILAAIPAGALVIDCSTIAPASARKVSEAAAARGLQMIDAPVSG 123 Query: 125 GTGGATAGTLTFMVGGTDDGFGLAKPYLEKMGKAIYHAGASGSGQTVKVCNNMLLGILMI 184 GT GA AGTLTF+VGG +D A+P L+ MGK I+H GASG+GQ K+CNNM LG++M Sbjct: 124 GTAGAQAGTLTFIVGGEEDALERARPVLQAMGKNIFHVGASGAGQVAKLCNNMALGVIMA 183 Query: 185 GTSEAIRLGIANGMDPKVLSEVMSKSSGRNWTLEVYNPCPGVMENAPASKGYAGGFGVDL 244 T EAI LG+A+G+DPKVLS++M+ S+GR+W EV NP PGV+ENAPAS+GY+GGFG DL Sbjct: 184 VTGEAIALGVAHGLDPKVLSQMMAVSTGRSWATEVCNPWPGVLENAPASRGYSGGFGSDL 243 Query: 245 MLKDLGLAVENALATGSSVPMGALARNLYDIHSKSGSGGLDFSSVFNMLAKAK 297 MLKD+GLAVE A++ G+S+P+G +ARNLY ++ ++G G LDFSSV ++ K Sbjct: 244 MLKDMGLAVEAAMSVGASIPLGEVARNLYSMNHQAGRGKLDFSSVVQLITSEK 296 >ref|YP_002026611.1| 3-hydroxyisobutyrate dehydrogenase [Stenotrophomonas maltophilia R551-3] gb|ACF49928.1| 3-hydroxyisobutyrate dehydrogenase [Stenotrophomonas maltophilia R551-3] Length = 296 Score = 352 bits (904), Expect = 3e-95, Method: Compositional matrix adjust. Identities = 177/293 (60%), Positives = 224/293 (76%) Query: 5 IVFIGLGNMGLPMAQNLVKAGYSVSGHDLVKASVDKLVESGGVTEADAMAAVAKAKVVIT 64 I FIGLGNMG PMA NLVK G++V DLV A+V V++G A A +A A+VVI+ Sbjct: 4 IAFIGLGNMGGPMAANLVKNGHTVRVFDLVPAAVQAAVDAGASAAASARETLADAEVVIS 63 Query: 65 MLPASKHVESIYLGDKGILANIKPGTLLIDCSTIAPESARMVAAAALEKGYTMLDAPVSG 124 MLPAS+HVE +YLGD GILA I G L+IDCSTIAP SAR V+ AA +G M+DAPVSG Sbjct: 64 MLPASRHVEGVYLGDDGILAAIPAGALVIDCSTIAPASARKVSEAAAARGLQMIDAPVSG 123 Query: 125 GTGGATAGTLTFMVGGTDDGFGLAKPYLEKMGKAIYHAGASGSGQTVKVCNNMLLGILMI 184 GT GA AGTLTF+VGG +D A+P L+ MGK I+H GASG+GQ K+CNNM LG++M Sbjct: 124 GTAGAQAGTLTFIVGGEEDALERARPVLQAMGKNIFHVGASGAGQVAKLCNNMALGVIMA 183 Query: 185 GTSEAIRLGIANGMDPKVLSEVMSKSSGRNWTLEVYNPCPGVMENAPASKGYAGGFGVDL 244 T EAI LG+A+G+DPKVLS++M+ S+GR+W EV NP PGV+ENAPAS+GY+GGFG DL Sbjct: 184 VTGEAIALGVAHGLDPKVLSQMMAVSTGRSWATEVCNPWPGVLENAPASRGYSGGFGSDL 243 Query: 245 MLKDLGLAVENALATGSSVPMGALARNLYDIHSKSGSGGLDFSSVFNMLAKAK 297 MLKD+GLAVE A++ G+S+P+G +ARNLY ++ ++G G LDFSSV ++ K Sbjct: 244 MLKDMGLAVEAAMSVGASIPLGEVARNLYSMNHQAGRGKLDFSSVVQLITSEK 296 >ref|YP_004790785.1| 3-hydroxyisobutyrate dehydrogenase [Burkholderia sp. JV3] gb|AEM49559.1| 3-hydroxyisobutyrate dehydrogenase [Burkholderia sp. JV3] Length = 296 Score = 351 bits (900), Expect = 1e-94, Method: Compositional matrix adjust. Identities = 176/289 (60%), Positives = 223/289 (77%) Query: 5 IVFIGLGNMGLPMAQNLVKAGYSVSGHDLVKASVDKLVESGGVTEADAMAAVAKAKVVIT 64 I FIGLGNMG PMA NLVK G+SV DLV A+V V++G + A +A A+VVI+ Sbjct: 4 IAFIGLGNMGGPMAANLVKNGHSVRVFDLVPAAVQAAVDAGASAASSARDTLAGAEVVIS 63 Query: 65 MLPASKHVESIYLGDKGILANIKPGTLLIDCSTIAPESARMVAAAALEKGYTMLDAPVSG 124 MLPAS+HVE +YLGD GILA I G L+IDCSTIAP SAR V+ AA +G M+DAPVSG Sbjct: 64 MLPASRHVEGVYLGDDGILAAIPAGALVIDCSTIAPASARKVSEAAAARGLQMIDAPVSG 123 Query: 125 GTGGATAGTLTFMVGGTDDGFGLAKPYLEKMGKAIYHAGASGSGQTVKVCNNMLLGILMI 184 GT GA AGTLTF+VGG +D A+P L+ MGK I+H GASG+GQ K+CNNM LG++M Sbjct: 124 GTAGAQAGTLTFIVGGEEDALERARPVLQAMGKNIFHVGASGAGQVAKLCNNMALGVIMA 183 Query: 185 GTSEAIRLGIANGMDPKVLSEVMSKSSGRNWTLEVYNPCPGVMENAPASKGYAGGFGVDL 244 T EAI LG+A+G+DPKVLS++M+ S+GR+W EV NP PGV+ENAPAS+GY+GGFG DL Sbjct: 184 VTGEAIALGVAHGLDPKVLSQMMAVSTGRSWATEVCNPWPGVLENAPASRGYSGGFGSDL 243 Query: 245 MLKDLGLAVENALATGSSVPMGALARNLYDIHSKSGSGGLDFSSVFNML 293 MLKD+GLAVE A++ G+S+P+G +ARNLY ++ ++G G LDFSSV ++ Sbjct: 244 MLKDMGLAVEAAMSVGASIPLGEVARNLYSMNHQAGRGKLDFSSVVQLI 292