BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0027.0059.p (332 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003776463.1| methylmalonate-semialdehyde dehydrogenase [H... 623 e-176 ref|YP_004753421.1| methylmalonate-semialdehyde dehydrogenase [C... 579 e-163 ref|YP_001630383.1| methylmalonate-semialdehyde dehydrogenase [B... 503 e-140 ref|YP_004125503.1| methylmalonate-semialdehyde dehydrogenase [A... 503 e-140 gb|EGP45189.1| methylmalonate-semialdehyde dehydrogenase [Achrom... 499 e-139 >ref|YP_003776463.1| methylmalonate-semialdehyde dehydrogenase [Herbaspirillum seropedicae SmR1] gb|ADJ64555.1| methylmalonate-semialdehyde dehydrogenase protein [Herbaspirillum seropedicae SmR1] Length = 506 Score = 623 bits (1607), Expect = e-176, Method: Compositional matrix adjust. Identities = 298/320 (93%), Positives = 312/320 (97%) Query: 1 MSQANIPNVPLYINGEHVQSTSKEWRDVINPATQEVVARVPFATKEEVDRAVANAKEAFK 60 MSQANIPNVPLY+NGE VQSTSKEWRDV+NPATQEVVARVPFATKEEVDRAVANAKE FK Sbjct: 1 MSQANIPNVPLYLNGEKVQSTSKEWRDVLNPATQEVVARVPFATKEEVDRAVANAKETFK 60 Query: 61 TWRNTSLAQRMRIMLKFQQLLRDNIAPLAEMITREHGKTLPDAEGEVMRGLEVVEHACSI 120 TWRNTSLAQRMRIMLKFQQLLR+NIAPLAE+ITREHGKTLPDAEGEVMRGLEVVEHACSI Sbjct: 61 TWRNTSLAQRMRIMLKFQQLLRENIAPLAELITREHGKTLPDAEGEVMRGLEVVEHACSI 120 Query: 121 TSLQLGELAENVAGGVDVYTIHQPIGVGAGITAFNFPVMLPCFMFPISVACGNTFVLKPS 180 TSLQLGELAENVAGGVDVYT++QP+GVGAGITAFNFPVMLPCFMFPI+VACGNTFVLKPS Sbjct: 121 TSLQLGELAENVAGGVDVYTLYQPLGVGAGITAFNFPVMLPCFMFPIAVACGNTFVLKPS 180 Query: 181 EQDPTSSLFLVELANKAGLPPGVLNVVHGGPEVANMICDHPDIKAVSFIGSTNVGTHIYR 240 EQDPTSSLFLVELAN+AGLPPGVLNVVHGGP+VANMICDHPDIKAVSFIGST+VGTHIYR Sbjct: 181 EQDPTSSLFLVELANQAGLPPGVLNVVHGGPDVANMICDHPDIKAVSFIGSTHVGTHIYR 240 Query: 241 RASEAGKRAQCMMGAKNHCIVLPDAPKDQAINNLLGAAFGAAGQRCMANSVVVLVGKTKE 300 RASEAGKRAQCMMGAKNHCIVLPDAPKDQAINNLLGAAFGAAGQRCMANSVVVLVG+T+E Sbjct: 241 RASEAGKRAQCMMGAKNHCIVLPDAPKDQAINNLLGAAFGAAGQRCMANSVVVLVGQTRE 300 Query: 301 WIPEIVERSKARAKTPTSAR 320 WIPEIVERSKA P + R Sbjct: 301 WIPEIVERSKAMKVGPGTDR 320 >ref|YP_004753421.1| methylmalonate-semialdehyde dehydrogenase [Collimonas fungivorans Ter331] gb|AEK62598.1| Methylmalonate-semialdehyde dehydrogenase [Collimonas fungivorans Ter331] Length = 507 Score = 579 bits (1492), Expect = e-163, Method: Compositional matrix adjust. Identities = 272/316 (86%), Positives = 295/316 (93%) Query: 5 NIPNVPLYINGEHVQSTSKEWRDVINPATQEVVARVPFATKEEVDRAVANAKEAFKTWRN 64 NIPN+PLY+ G+ VQS S EWRDV+NPATQEVVARVPFATK EVD AVA+AK+AF +WRN Sbjct: 10 NIPNIPLYVGGKTVQSASTEWRDVLNPATQEVVARVPFATKAEVDHAVADAKQAFASWRN 69 Query: 65 TSLAQRMRIMLKFQQLLRDNIAPLAEMITREHGKTLPDAEGEVMRGLEVVEHACSITSLQ 124 TSLAQRMRIMLKFQQLLR+NIAPLAE+ITREHGKTLPDAEGEVMRGLEVVEHACSITSLQ Sbjct: 70 TSLAQRMRIMLKFQQLLRENIAPLAELITREHGKTLPDAEGEVMRGLEVVEHACSITSLQ 129 Query: 125 LGELAENVAGGVDVYTIHQPIGVGAGITAFNFPVMLPCFMFPISVACGNTFVLKPSEQDP 184 LGELAEN A GVDVYTI+QP+GVGAGITAFNFPVMLPCFMFP++VACGNTF+LKPSEQDP Sbjct: 130 LGELAENAATGVDVYTINQPLGVGAGITAFNFPVMLPCFMFPVAVACGNTFILKPSEQDP 189 Query: 185 TSSLFLVELANKAGLPPGVLNVVHGGPEVANMICDHPDIKAVSFIGSTNVGTHIYRRASE 244 +SSLFLVELA +AGLPPGVLNVVHGGPEVANM+CDHPDIKA+SFIGST VGTHIYRRASE Sbjct: 190 SSSLFLVELAQQAGLPPGVLNVVHGGPEVANMLCDHPDIKAISFIGSTTVGTHIYRRASE 249 Query: 245 AGKRAQCMMGAKNHCIVLPDAPKDQAINNLLGAAFGAAGQRCMANSVVVLVGKTKEWIPE 304 AGKRAQCMMGAKNHCIVLPDA KDQAINNLLGAAFGAAGQRCMANS+V+LVGK + W+PE Sbjct: 250 AGKRAQCMMGAKNHCIVLPDANKDQAINNLLGAAFGAAGQRCMANSMVLLVGKARSWLPE 309 Query: 305 IVERSKARAKTPTSAR 320 IVERS+ P S R Sbjct: 310 IVERSRGLKIGPGSDR 325 >ref|YP_001630383.1| methylmalonate-semialdehyde dehydrogenase [Bordetella petrii DSM 12804] emb|CAP42114.1| methylmalonate-semialdehyde dehydrogenase [Bordetella petrii] Length = 497 Score = 503 bits (1295), Expect = e-140, Method: Compositional matrix adjust. Identities = 237/308 (76%), Positives = 270/308 (87%) Query: 4 ANIPNVPLYINGEHVQSTSKEWRDVINPATQEVVARVPFATKEEVDRAVANAKEAFKTWR 63 + +P+VPL I G+ VQS + EWRDVI+PATQ+VVARVPFAT+EE+D AVANAKEAF+TWR Sbjct: 2 SEVPSVPLLIGGKLVQSKTTEWRDVIDPATQQVVARVPFATREELDLAVANAKEAFQTWR 61 Query: 64 NTSLAQRMRIMLKFQQLLRDNIAPLAEMITREHGKTLPDAEGEVMRGLEVVEHACSITSL 123 NT RMR+MLK QQLLR+N A LAEMITREHGKTLPDAEGEV RGLEVVEHACSI +L Sbjct: 62 NTGQGARMRVMLKLQQLLRENTAKLAEMITREHGKTLPDAEGEVGRGLEVVEHACSIANL 121 Query: 124 QLGELAENVAGGVDVYTIHQPIGVGAGITAFNFPVMLPCFMFPISVACGNTFVLKPSEQD 183 QLGE AEN AGG+DVYT+ QP+GV AGITAFNFPVMLPCFMFPI+VACGNTFVLKPSEQD Sbjct: 122 QLGEYAENAAGGIDVYTLIQPLGVCAGITAFNFPVMLPCFMFPIAVACGNTFVLKPSEQD 181 Query: 184 PTSSLFLVELANKAGLPPGVLNVVHGGPEVANMICDHPDIKAVSFIGSTNVGTHIYRRAS 243 PTSSLFL +LA +AGLPPGVLNVVHGGPE+AN +C+HPDIKAVSFIGST VG+ IY+RAS Sbjct: 182 PTSSLFLAQLALEAGLPPGVLNVVHGGPEIANGLCEHPDIKAVSFIGSTRVGSEIYQRAS 241 Query: 244 EAGKRAQCMMGAKNHCIVLPDAPKDQAINNLLGAAFGAAGQRCMANSVVVLVGKTKEWIP 303 AGKR Q MMGAKNHC++LPDA + A+N LLGAAFGAAGQRCMA SV VLVG+ + W+P Sbjct: 242 NAGKRCQAMMGAKNHCVILPDADPEVALNQLLGAAFGAAGQRCMAASVAVLVGEARNWLP 301 Query: 304 EIVERSKA 311 + VER+K Sbjct: 302 DFVERAKG 309 >ref|YP_004125503.1| methylmalonate-semialdehyde dehydrogenase [Alicycliphilus denitrificans BC] ref|YP_004386738.1| methylmalonate-semialdehyde dehydrogenase [Alicycliphilus denitrificans K601] gb|ADU98615.1| methylmalonate-semialdehyde dehydrogenase [Alicycliphilus denitrificans BC] gb|AEB83222.1| methylmalonate-semialdehyde dehydrogenase [Alicycliphilus denitrificans K601] Length = 501 Score = 503 bits (1294), Expect = e-140, Method: Compositional matrix adjust. Identities = 233/309 (75%), Positives = 275/309 (88%) Query: 12 YINGEHVQSTSKEWRDVINPATQEVVARVPFATKEEVDRAVANAKEAFKTWRNTSLAQRM 71 +I G+ S S EWRDV NPATQEVVARVPFAT+EEV+ AVANA+EAF+TWR TSL+ RM Sbjct: 10 FIGGKPYPSKSAEWRDVTNPATQEVVARVPFATREEVELAVANAQEAFQTWRETSLSARM 69 Query: 72 RIMLKFQQLLRDNIAPLAEMITREHGKTLPDAEGEVMRGLEVVEHACSITSLQLGELAEN 131 RIMLK Q L+R++ A +A++ITREHGKTLPDAEGEV RGLEVVEHACSIT+LQLGE+AEN Sbjct: 70 RIMLKLQHLIREHQAEIAQLITREHGKTLPDAEGEVGRGLEVVEHACSITTLQLGEIAEN 129 Query: 132 VAGGVDVYTIHQPIGVGAGITAFNFPVMLPCFMFPISVACGNTFVLKPSEQDPTSSLFLV 191 A GVDVY + QP+GVGAGITAFNFPVMLPCFMFP+++ACGNTFVLKPSEQDP+S++ LV Sbjct: 130 AATGVDVYNLLQPLGVGAGITAFNFPVMLPCFMFPMAIACGNTFVLKPSEQDPSSTMRLV 189 Query: 192 ELANKAGLPPGVLNVVHGGPEVANMICDHPDIKAVSFIGSTNVGTHIYRRASEAGKRAQC 251 ELA++AG+PPGVLNV+HGGPEVA+M+CDHPDIKA+SFIGST+VGTHIYRRASEAGKR Q Sbjct: 190 ELAHEAGVPPGVLNVIHGGPEVADMLCDHPDIKALSFIGSTHVGTHIYRRASEAGKRVQS 249 Query: 252 MMGAKNHCIVLPDAPKDQAINNLLGAAFGAAGQRCMANSVVVLVGKTKEWIPEIVERSKA 311 MMGAKNHC+V+PDAPK+ A+NNLLG+AFGAAGQRCMANSV V VG ++W+PE+V +SKA Sbjct: 250 MMGAKNHCVVMPDAPKEHALNNLLGSAFGAAGQRCMANSVAVFVGAARDWLPELVAKSKA 309 Query: 312 RAKTPTSAR 320 P + R Sbjct: 310 MKVGPGTDR 318 >gb|EGP45189.1| methylmalonate-semialdehyde dehydrogenase [Achromobacter xylosoxidans AXX-A] Length = 504 Score = 499 bits (1285), Expect = e-139, Method: Compositional matrix adjust. Identities = 235/307 (76%), Positives = 266/307 (86%) Query: 4 ANIPNVPLYINGEHVQSTSKEWRDVINPATQEVVARVPFATKEEVDRAVANAKEAFKTWR 63 + +P VPL I G+ VQS + EWRDVINPATQEVVA+VPFAT++E+D A+AN+KEAFKTWR Sbjct: 9 SEVPRVPLLIGGKLVQSKTTEWRDVINPATQEVVAKVPFATRDELDEAIANSKEAFKTWR 68 Query: 64 NTSLAQRMRIMLKFQQLLRDNIAPLAEMITREHGKTLPDAEGEVMRGLEVVEHACSITSL 123 N+ RMR+MLKFQ+LLR N LAEMITREHGKTLPDAEGEV RGLEVVEHACSI +L Sbjct: 69 NSGQGLRMRVMLKFQELLRANTGKLAEMITREHGKTLPDAEGEVGRGLEVVEHACSIANL 128 Query: 124 QLGELAENVAGGVDVYTIHQPIGVGAGITAFNFPVMLPCFMFPISVACGNTFVLKPSEQD 183 QLGE AEN A G+DVYT+ QP+GV AGITAFNFPVMLPCFMFPI+VACGNTFVLKPSEQD Sbjct: 129 QLGEYAENAASGIDVYTLIQPLGVCAGITAFNFPVMLPCFMFPIAVACGNTFVLKPSEQD 188 Query: 184 PTSSLFLVELANKAGLPPGVLNVVHGGPEVANMICDHPDIKAVSFIGSTNVGTHIYRRAS 243 PTSSLFL +LA +AGLPPGVLNVVHGGPE AN +C+HPDIKAVSFIGST VGT IY RAS Sbjct: 189 PTSSLFLAQLALEAGLPPGVLNVVHGGPETANGLCEHPDIKAVSFIGSTRVGTEIYNRAS 248 Query: 244 EAGKRAQCMMGAKNHCIVLPDAPKDQAINNLLGAAFGAAGQRCMANSVVVLVGKTKEWIP 303 AGKR Q MMGAKNHC++LPDA D A+N LLGAAFGAAGQRCMA+SV VLVG+ + W+P Sbjct: 249 AAGKRCQSMMGAKNHCVILPDADPDVALNQLLGAAFGAAGQRCMASSVAVLVGEARNWLP 308 Query: 304 EIVERSK 310 + VER+K Sbjct: 309 DFVERAK 315