BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0026.0085.p (321 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003774878.1| dihydrolipoamide acetyltransferase component... 575 e-162 ref|YP_004754205.1| dihydrolipoamide acetyltransferase component... 508 e-142 ref|YP_001352364.1| pyruvate dehydrogenase E2 component (dihydro... 493 e-137 ref|YP_001099068.1| dihydrolipoyllysine-residue acetyltransferas... 487 e-136 ref|YP_004235229.1| pyruvate dehydrogenase complex dihydrolipoam... 435 e-120 >ref|YP_003774878.1| dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex [Herbaspirillum seropedicae SmR1] gb|ADJ62970.1| dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex (E2) protein [Herbaspirillum seropedicae SmR1] Length = 554 Score = 575 bits (1481), Expect = e-162, Method: Compositional matrix adjust. Identities = 279/314 (88%), Positives = 294/314 (93%), Gaps = 1/314 (0%) Query: 9 SSVNKSHASPSVRKYGRELGVDLTRVVGTGPKNRILQEDIQKFVKAALAGA-GTAASAPA 67 S+ K+HASPSVRK+ RELGVDL+RV TGPK RILQ D+Q FVK +AG+ AASAPA Sbjct: 241 STGGKAHASPSVRKFARELGVDLSRVPATGPKGRILQLDVQNFVKGVMAGSTSVAASAPA 300 Query: 68 KNGSGVGLDLLPWPSLDFSKFGTTELLPLSRIKKISGPNLHRNWVMIPHVTQFDEADVTE 127 NGSG G++LLPWPSLDFSKFG TEL PLSRIKKISGPNLHRNWVMIPHVTQFDEADVTE Sbjct: 301 TNGSGAGMNLLPWPSLDFSKFGETELQPLSRIKKISGPNLHRNWVMIPHVTQFDEADVTE 360 Query: 128 LEEFRKTSNDAYAKAKSPVKLTMLAFVIKASVSALKKFPAFNSSLDAKGENLILKQYYNI 187 LEEFRKTSNDA+AKAKSPVKLTMLAFVIKASVSALKKFPAFNSSLDAKGENLILK++YNI Sbjct: 361 LEEFRKTSNDAFAKAKSPVKLTMLAFVIKASVSALKKFPAFNSSLDAKGENLILKKFYNI 420 Query: 188 GFAADTPNGLVVPVIKNADQKTIGQIATEMGELSAQARDGKLKPADMQGATFTISSLGGI 247 GFAADTPNGLVVPVIKNADQK+IGQIA EMGELSAQARDGKLKPADMQGATFTISSLGGI Sbjct: 421 GFAADTPNGLVVPVIKNADQKSIGQIAIEMGELSAQARDGKLKPADMQGATFTISSLGGI 480 Query: 248 GGTAFTPIINAPEVAILGLSKSIIKPVWDGKQFAPRLMLPTSLSYDHRVVDGAMGARFSA 307 GGTAFTPIINAPEVAILGLSKSI KPVWDGKQF PRLMLPTSLSYDHRV+DGAMGARFSA Sbjct: 481 GGTAFTPIINAPEVAILGLSKSITKPVWDGKQFVPRLMLPTSLSYDHRVIDGAMGARFSA 540 Query: 308 YLAEVLGDLRKSLL 321 YLA+VLGDLRKSLL Sbjct: 541 YLADVLGDLRKSLL 554 >ref|YP_004754205.1| dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex [Collimonas fungivorans Ter331] gb|AEK63382.1| Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex [Collimonas fungivorans Ter331] Length = 442 Score = 508 bits (1309), Expect = e-142, Method: Compositional matrix adjust. Identities = 253/309 (81%), Positives = 278/309 (89%), Gaps = 2/309 (0%) Query: 15 HASPSVRKYGRELGVDLTRVVGTGPKNRILQEDIQKFVKAALAGAGTAASAPAKNGSGVG 74 HASPSVRK+ RELGVDL++V GTG K RI ED+Q +VK ++GA + ++A A G G Sbjct: 134 HASPSVRKFARELGVDLSKVAGTGIKARITHEDVQNYVKGVISGAASGSAAAAGGKGGSG 193 Query: 75 --LDLLPWPSLDFSKFGTTELLPLSRIKKISGPNLHRNWVMIPHVTQFDEADVTELEEFR 132 LDLL WPSLDFSK G TELLPLSRIKK+SGPNLHRNWVMIPHVTQFDEAD+TELEEFR Sbjct: 194 VGLDLLAWPSLDFSKQGPTELLPLSRIKKLSGPNLHRNWVMIPHVTQFDEADITELEEFR 253 Query: 133 KTSNDAYAKAKSPVKLTMLAFVIKASVSALKKFPAFNSSLDAKGENLILKQYYNIGFAAD 192 K +ND++AKAKSPVKLTMLAFVIKASV+ALKKFPAFN+SLD KGENLILK+YYNIGFAAD Sbjct: 254 KQANDSFAKAKSPVKLTMLAFVIKASVAALKKFPAFNASLDGKGENLILKRYYNIGFAAD 313 Query: 193 TPNGLVVPVIKNADQKTIGQIATEMGELSAQARDGKLKPADMQGATFTISSLGGIGGTAF 252 TPNGLVVPVIK+AD+K I QIA EMGELSAQARDGKLKPADMQGATFTISSLGGIGGTAF Sbjct: 314 TPNGLVVPVIKDADKKGISQIAQEMGELSAQARDGKLKPADMQGATFTISSLGGIGGTAF 373 Query: 253 TPIINAPEVAILGLSKSIIKPVWDGKQFAPRLMLPTSLSYDHRVVDGAMGARFSAYLAEV 312 TPIINAPEVAILGLSK+ +KPVWDGKQF PRLM+PTSLSYDHRVVDGAMGARFS YLAEV Sbjct: 374 TPIINAPEVAILGLSKASMKPVWDGKQFVPRLMMPTSLSYDHRVVDGAMGARFSVYLAEV 433 Query: 313 LGDLRKSLL 321 L D+RK+LL Sbjct: 434 LADMRKTLL 442 >ref|YP_001352364.1| pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase) [Janthinobacterium sp. Marseille] gb|ABR88599.1| pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase) [Janthinobacterium sp. Marseille] Length = 458 Score = 493 bits (1268), Expect = e-137, Method: Compositional matrix adjust. Identities = 243/312 (77%), Positives = 271/312 (86%), Gaps = 4/312 (1%) Query: 12 NKSHASPSVRKYGRELGVDLTRVVGTGPKNRILQEDIQKFVKAALAGAGTAASAPA--KN 69 +K+HASPS+RK+ RELGVDL +V G+GPK RI QED+Q +VK +A AA+A A K+ Sbjct: 149 SKAHASPSIRKFARELGVDLGKVAGSGPKGRITQEDVQNYVKGIIAAGPVAATAAAPVKS 208 Query: 70 GSGVGLDLLPWPSLDFSKFGTTELLPLSRIKKISGPNLHRNWVMIPHVTQFDEADVTELE 129 G G GLDLLPWPSLDFSKFGTT L PLSRIKKISGPNLHRNWVMIPHVTQ+DEADVTELE Sbjct: 209 GGGAGLDLLPWPSLDFSKFGTTTLQPLSRIKKISGPNLHRNWVMIPHVTQYDEADVTELE 268 Query: 130 EFRKTSNDAYAKAKSPVKLTMLAFVIKASVSALKKFPAFNSSLDAKGENLILKQYYNIGF 189 E RK++N A AK S VKLTMLAFVIKA V+ALKK+P FNSSLDA GENLILKQYYNIGF Sbjct: 269 ELRKSTNTALAK--SGVKLTMLAFVIKACVAALKKYPEFNSSLDANGENLILKQYYNIGF 326 Query: 190 AADTPNGLVVPVIKNADQKTIGQIATEMGELSAQARDGKLKPADMQGATFTISSLGGIGG 249 AADTP GLVVPV+K DQKT+ QIA EMG+LSAQAR+GKLKPADMQGATFTISSLGGIGG Sbjct: 327 AADTPQGLVVPVVKGVDQKTVTQIAQEMGDLSAQAREGKLKPADMQGATFTISSLGGIGG 386 Query: 250 TAFTPIINAPEVAILGLSKSIIKPVWDGKQFAPRLMLPTSLSYDHRVVDGAMGARFSAYL 309 T FTP+INAPEVAI+GLSK+ +KPVWDGKQF PRL++P SLSYDHRV+DGA GARF YL Sbjct: 387 TYFTPLINAPEVAIIGLSKTSMKPVWDGKQFVPRLIMPLSLSYDHRVIDGAQGARFVTYL 446 Query: 310 AEVLGDLRKSLL 321 +EVL DLRKSLL Sbjct: 447 SEVLSDLRKSLL 458 >ref|YP_001099068.1| dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex (E2) (dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex) [Herminiimonas arsenicoxydans] emb|CAL60941.1| Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex (E2) (Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex) [Herminiimonas arsenicoxydans] Length = 455 Score = 487 bits (1254), Expect = e-136, Method: Compositional matrix adjust. Identities = 240/310 (77%), Positives = 264/310 (85%), Gaps = 8/310 (2%) Query: 17 SPSVRKYGRELGVDLTRVVGTGPKNRILQEDIQKFVKAALAGAGTAASAP-----AKNGS 71 SPS+RK+ RELGVDL V G+GPK RI Q+D+Q +VK ALA AG +SAP + Sbjct: 149 SPSIRKFARELGVDLGSVAGSGPKGRITQQDVQTYVKTALA-AGPVSSAPVAAPPGASRG 207 Query: 72 GVGLDLLPWPSLDFSKFGTTELLPLSRIKKISGPNLHRNWVMIPHVTQFDEADVTELEEF 131 G GLDLLPWPSLDFSKFG T L PLSRIKKISGPNLHRNWVMIPHVTQ+DEADVTELEE Sbjct: 208 GAGLDLLPWPSLDFSKFGETTLQPLSRIKKISGPNLHRNWVMIPHVTQYDEADVTELEEL 267 Query: 132 RKTSNDAYAKAKSPVKLTMLAFVIKASVSALKKFPAFNSSLDAKGENLILKQYYNIGFAA 191 RK++N A AK S VKLT+LAFVIKA V+ALKK+P FNSSLDA GENLILKQYYNIGFAA Sbjct: 268 RKSTNTALAK--SGVKLTILAFVIKACVAALKKYPEFNSSLDAAGENLILKQYYNIGFAA 325 Query: 192 DTPNGLVVPVIKNADQKTIGQIATEMGELSAQARDGKLKPADMQGATFTISSLGGIGGTA 251 DTP GLVVPV+K DQKT+ QIA EMGELSAQARDGKLKPADMQGATFTISSLGGIGGT Sbjct: 326 DTPQGLVVPVVKGVDQKTVTQIAQEMGELSAQARDGKLKPADMQGATFTISSLGGIGGTY 385 Query: 252 FTPIINAPEVAILGLSKSIIKPVWDGKQFAPRLMLPTSLSYDHRVVDGAMGARFSAYLAE 311 FTP+INAPEVAI+GLSK+ +KPVWDGKQF PRL++P SLSYDHRV+DGA GARF YL+E Sbjct: 386 FTPLINAPEVAIIGLSKTSMKPVWDGKQFVPRLIMPLSLSYDHRVIDGAQGARFVTYLSE 445 Query: 312 VLGDLRKSLL 321 VL DLRKSLL Sbjct: 446 VLTDLRKSLL 455 >ref|YP_004235229.1| pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase [Acidovorax avenae subsp. avenae ATCC 19860] gb|ADX46662.1| pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase [Acidovorax avenae subsp. avenae ATCC 19860] Length = 565 Score = 435 bits (1118), Expect = e-120, Method: Compositional matrix adjust. Identities = 216/311 (69%), Positives = 247/311 (79%), Gaps = 8/311 (2%) Query: 15 HASPSVRKYGRELGVDLTRVVGTGPKNRILQEDIQKFVKAALAGA----GTAASAPAKNG 70 HASPSVRK+ RELGV L + G+GPK RI QED+Q F + +AG AA APA G Sbjct: 259 HASPSVRKFARELGVPLEEIKGSGPKGRITQEDVQAFTRQVMAGGVQTKAQAAKAPAGGG 318 Query: 71 SGVGLDLLPWPSLDFSKFGTTELLPLSRIKKISGPNLHRNWVMIPHVTQFDEADVTELEE 130 SGVG+DLLPWP +DFSKFG E LSRIKKISG NLHRNWVMIPHVT DEAD+TELE Sbjct: 319 SGVGMDLLPWPKVDFSKFGGVERKDLSRIKKISGANLHRNWVMIPHVTNNDEADITELEA 378 Query: 131 FRKTSNDAYAKAKSPVKLTMLAFVIKASVSALKKFPAFNSSLDAKGENLILKQYYNIGFA 190 FR ++N KS VK+TMLAFVIKA V+ALKKFP FN+SLD G+ L+ KQY++IGFA Sbjct: 379 FRVSTN--KENEKSGVKVTMLAFVIKAVVAALKKFPEFNTSLD--GDTLVYKQYFHIGFA 434 Query: 191 ADTPNGLVVPVIKNADQKTIGQIATEMGELSAQARDGKLKPADMQGATFTISSLGGIGGT 250 ADTPNGLVVPV+K+AD+K I QI+ EMGEL+ +ARDGKL ADMQG F+ISSLGGIGGT Sbjct: 435 ADTPNGLVVPVLKDADKKGILQISQEMGELAKKARDGKLGAADMQGGCFSISSLGGIGGT 494 Query: 251 AFTPIINAPEVAILGLSKSIIKPVWDGKQFAPRLMLPTSLSYDHRVVDGAMGARFSAYLA 310 FTPIINAPEVAILGLSK +KPVWDGKQF PRL+LP SLSYDHRV+DGA ARF+AYL Sbjct: 495 HFTPIINAPEVAILGLSKGQMKPVWDGKQFVPRLVLPLSLSYDHRVIDGASAARFNAYLG 554 Query: 311 EVLGDLRKSLL 321 +VL D R+ LL Sbjct: 555 QVLADYRRILL 565