BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0026.0074.p (297 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003776725.1| D-3-phosphoglycerate dehydrogenase [Herbaspi... 471 e-131 ref|YP_003409482.1| NAD-binding D-isomer specific 2-hydroxyacid ... 287 2e-75 ref|YP_003322014.1| D-isomer specific 2-hydroxyacid dehydrogenas... 263 3e-68 ref|YP_003652189.1| NAD-binding D-isomer specific 2-hydroxyacid ... 219 4e-55 ref|YP_003298087.1| NAD-binding D-isomer specific 2-hydroxyacid ... 214 1e-53 >ref|YP_003776725.1| D-3-phosphoglycerate dehydrogenase [Herbaspirillum seropedicae SmR1] gb|ADJ64817.1| D-3-phosphoglycerate dehydrogenase protein [Herbaspirillum seropedicae SmR1] Length = 319 Score = 471 bits (1213), Expect = e-131, Method: Compositional matrix adjust. Identities = 238/283 (84%), Positives = 260/283 (91%), Gaps = 1/283 (0%) Query: 16 EVIKAAEGCEGLLVQYAPVNAKVFAARPEIRIASRYGAGFDTINTDDAAKHGVWVGNSPD 75 EVI A+ GC+GLLVQYAPVNAKVFAARPEIRIASRYGAGFDTINT DAA HGVWV NSPD Sbjct: 37 EVIAASAGCQGLLVQYAPVNAKVFAARPEIRIASRYGAGFDTINTADAAAHGVWVANSPD 96 Query: 76 YGVGEVSTHALAMALDLIRNITGYDRDVKSGQWHYTTAGKIQRCSEMTIGIVGLGRIGKR 135 YGVGEV+THALAMALDLIRNIT YDR VK+G+WHYTTAG I R S++TIGI+GLGRIGKR Sbjct: 97 YGVGEVATHALAMALDLIRNITVYDRAVKAGEWHYTTAGIIPRASDLTIGIIGLGRIGKR 156 Query: 136 MAHISRNLFKRVIAYDPHIIDGDFPAYVERVGKEELFRQAHVVSLHTPLNDETRGMIDSS 195 MAHISRNLFKRVIAYDP+IIDGDFPAYVERVG+EELFRQAHVVSLHTPLNDETR MID+S Sbjct: 157 MAHISRNLFKRVIAYDPYIIDGDFPAYVERVGREELFRQAHVVSLHTPLNDETRNMIDAS 216 Query: 196 VLKLMQQDSFLVNSARGGLVNIDDLLKALDT-NLKGAGLDVLPVEPPETSSAIVQHKRVL 254 +L L+Q S+LVNSARGGLV IDDLL AL+ LKGA LDVLPVEPP+T+SAIVQH RVL Sbjct: 217 LLDLLQAQSYLVNSARGGLVKIDDLLAALENGKLKGAALDVLPVEPPQTASAIVQHPRVL 276 Query: 255 LSPHAAFYSEVAARELRRKAAQNLIDWDRNGRPSYVVVEGRKK 297 LSPHAAF+S+VAARELRRKAA+NLIDWDR GRPSYVVV+G+ K Sbjct: 277 LSPHAAFFSDVAARELRRKAAKNLIDWDRTGRPSYVVVQGKNK 319 >ref|YP_003409482.1| NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase protein [Geodermatophilus obscurus DSM 43160] gb|ADB75111.1| D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein [Geodermatophilus obscurus DSM 43160] Length = 322 Score = 287 bits (734), Expect = 2e-75, Method: Compositional matrix adjust. Identities = 145/290 (50%), Positives = 195/290 (67%), Gaps = 4/290 (1%) Query: 7 RCIATPALXEVIKAAEGCEGLLVQYAPVNAKVFAARPEIRIASRYGAGFDTINTDDAAKH 66 RC TPA EVI AA + +LVQYAP+ A+V A P +R+ SRYG G D ++TD A Sbjct: 36 RC-RTPA--EVIDAARDADAVLVQYAPITAEVLDALPRLRLVSRYGVGVDVVDTDAARAR 92 Query: 67 GVWVGNSPDYGVGEVSTHALAMALDLIRNITGYDRDVKSGQWHYTTAGKIQRCSEMTIGI 126 GVWV N PDYG EV+ HA+A+ L L+RN+ +DR V +G+W + G+++R +T+G+ Sbjct: 93 GVWVCNVPDYGTTEVALHAVAVLLALLRNLPEHDRQVHAGRWDHRLGGRLRRPDGLTLGV 152 Query: 127 VGLGRIGKRMAHISRNLFKRVIAYDPHIIDGDFPAYVERVGKEELFRQAHVVSLHTPLND 186 VGLGRIG+ + F V+ +DPH+ D +PA VER+G ELF ++ V+LH PL Sbjct: 153 VGLGRIGRTTMAGAAPWFGAVVGHDPHLPDDAWPAGVERLGLAELFARSDAVTLHLPLTA 212 Query: 187 ETRGMIDSSVLKLMQQDSFLVNSARGGLVNIDDLLKAL-DTNLKGAGLDVLPVEPPETSS 245 +TRG++ + +L M S+LVN+ARGGLV +D +L+AL D L G GLDV P EPP S Sbjct: 213 DTRGLVGADLLGRMPAGSYLVNTARGGLVQLDAVLQALEDGRLAGVGLDVFPTEPPPAGS 272 Query: 246 AIVQHKRVLLSPHAAFYSEVAARELRRKAAQNLIDWDRNGRPSYVVVEGR 295 ++ H R LL+PH A+YSE A ELRRKAA N++ W R GRP +VVVEGR Sbjct: 273 PLLAHPRALLTPHVAWYSEEAEVELRRKAAGNVVSWARTGRPDHVVVEGR 322 >ref|YP_003322014.1| D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein [Thermobaculum terrenum ATCC BAA-798] gb|ACZ41192.1| D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein [Thermobaculum terrenum ATCC BAA-798] Length = 324 Score = 263 bits (671), Expect = 3e-68, Method: Compositional matrix adjust. Identities = 133/278 (47%), Positives = 189/278 (67%), Gaps = 1/278 (0%) Query: 16 EVIKAAEGCEGLLVQYAPVNAKVFAARPEIRIASRYGAGFDTINTDDAAKHGVWVGNSPD 75 EVI AA L+VQYAP+ + V A P +++ SR G G D+++ D A + GVWV N PD Sbjct: 40 EVILAARDAFALMVQYAPITSDVIHALPNLKLISRAGVGVDSVDLDAAKEKGVWVANVPD 99 Query: 76 YGVGEVSTHALAMALDLIRNITGYDRDVKSGQWHYTTAGKIQRCSEMTIGIVGLGRIGKR 135 YGV EV++HA AM L L+R++ DR V+ G WHY + G+I R S +T+G+VGLGRIG+ Sbjct: 100 YGVHEVASHAAAMILSLLRHVCFLDRKVREGVWHYLSTGEIHRISSLTLGVVGLGRIGRT 159 Query: 136 MAHISRNLFKRVIAYDPHIIDGDFPAYVERVGKEELFRQAHVVSLHTPLNDETRGMIDSS 195 +A + ++F RVI YDP++ +P V+RV +LF +++VVSLH PL ET M++ Sbjct: 160 LASMMLHVFGRVIGYDPYLPANAWPEGVDRVDLRDLFMKSNVVSLHLPLTKETSNMVNRE 219 Query: 196 VLKLMQQDSFLVNSARGGLVNIDDLLKALDT-NLKGAGLDVLPVEPPETSSAIVQHKRVL 254 L LM S+LVN+ARGGLVN++DL+ LD+ +L GA LDVLP EPP I+ H +++ Sbjct: 220 FLALMPVGSYLVNTARGGLVNMEDLIYFLDSGHLAGAALDVLPKEPPVAGDPIIHHPKII 279 Query: 255 LSPHAAFYSEVAARELRRKAAQNLIDWDRNGRPSYVVV 292 ++PH A+YSE + +ELR K A N++ + +NG P Y VV Sbjct: 280 ITPHVAWYSEESEKELRYKWAMNVVAFLKNGSPLYPVV 317 >ref|YP_003652189.1| NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase protein [Thermobispora bispora DSM 43833] gb|ADG88296.1| D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein [Thermobispora bispora DSM 43833] Length = 332 Score = 219 bits (558), Expect = 4e-55, Method: Compositional matrix adjust. Identities = 120/270 (44%), Positives = 167/270 (61%), Gaps = 2/270 (0%) Query: 27 LLVQYAPVNAKVFAARPEIRIASRYGAGFDTINTDDAAKHGVWVGNSPDYGVGEVSTHAL 86 LL+ Y PV A++ P +R+ AG+DT++ A + G+WV N PD EV++HAL Sbjct: 55 LLIGYCPVTAELLDRLPRLRLICTQSAGYDTVDVAAARERGIWVANVPDAATEEVASHAL 114 Query: 87 AMALDLIRNITGYDRDVKSGQWHYTTAGKIQRCSEMTIGIVGLGRIGKRMAHISRNLFKR 146 AMAL L+R + DR V++G+W TA + +R S T+GI+G+GRIG+R+A ++ LF Sbjct: 115 AMALGLLRGLPFLDRRVRAGEWD-GTAERPRRISAATLGIIGMGRIGRRLAGMASGLFGE 173 Query: 147 VIAYDPHIIDGDFPAYVERVGKEELFRQAHVVSLHTPLNDETRGMIDSSVLKLMQQDSFL 206 V+ +DP +P V RVG EL + VVSLH PL +ETRGM+ L M+ + L Sbjct: 174 VLGHDPLAGGAQWPPGVRRVGLRELLSSSDVVSLHVPLTEETRGMLGREELAAMRPGAAL 233 Query: 207 VNSARGGLVNIDDLLKALDT-NLKGAGLDVLPVEPPETSSAIVQHKRVLLSPHAAFYSEV 265 N ARG LV+ D L LD+ +L GA LDVLPVEPP A+++H R+L +PHAA+ SE Sbjct: 234 ANVARGELVDHDALADLLDSGHLMGAALDVLPVEPPPAGWALLRHPRILFTPHAAYLSEH 293 Query: 266 AARELRRKAAQNLIDWDRNGRPSYVVVEGR 295 +A A+N + W R G P +VVV GR Sbjct: 294 SAASYVLTQAENAVAWLRTGEPIHVVVRGR 323 >ref|YP_003298087.1| NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase protein [Thermomonospora curvata DSM 43183] gb|ACY96049.1| D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein [Thermomonospora curvata DSM 43183] Length = 321 Score = 214 bits (545), Expect = 1e-53, Method: Compositional matrix adjust. Identities = 114/266 (42%), Positives = 164/266 (61%), Gaps = 5/266 (1%) Query: 31 YAPVNAKVFAARPEIRIASRYGAGFDTINTDDAAKHGVWVGNSPDYGVGEVSTHALAMAL 90 YA ++ + A P +RI + G+D ++ D + G+WV N P EV++HALAM L Sbjct: 55 YAEIDRPLLEALPAVRIVATQSVGYDMVDLDACRERGIWVTNVPGAATEEVASHALAMTL 114 Query: 91 DLIRNITGYDRDVKSGQWHYTTAGKIQRCSEMTIGIVGLGRIGKRMAHISRNLFKRVIAY 150 L+R + DRDV++G W T ++R SE+T+G+VGLGRIG+R A R L R++ Y Sbjct: 115 ALLRGLPYLDRDVRAGIWD-GTRHDLRRLSEVTVGVVGLGRIGRRYAEYVRPLVGRIVGY 173 Query: 151 DPHIIDGDFPAYVERVGKEELFRQAHVVSLHTPLNDETRGMIDSSVLKLMQQDSFLVNSA 210 DP + V+ + +EL + VVSLH PL ETRG++D+ L LM++ + LVN + Sbjct: 174 DPAVTAMHG---VQWLALDELLACSDVVSLHLPLTAETRGLLDARRLGLMREGASLVNVS 230 Query: 211 RGGLVNIDDLLKALDTN-LKGAGLDVLPVEPPETSSAIVQHKRVLLSPHAAFYSEVAARE 269 R GL++ L++ LD L GA LDVLP EPPE I+ H RVLL+PHAA+ S ++R+ Sbjct: 231 RAGLIDHRALVRCLDEGRLSGAALDVLPQEPPEPGDPILAHPRVLLTPHAAYLSAASSRD 290 Query: 270 LRRKAAQNLIDWDRNGRPSYVVVEGR 295 + A+N++ W GRP VVVEGR Sbjct: 291 YVLQQAENVVLWHARGRPVSVVVEGR 316