BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0025.0119.p (260 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_004752066.1| uroporphyrinogen III synthase [Collimonas fu... 266 3e-69 ref|YP_003776320.1| uroporphyrinogen-III synthase [Herbaspirillu... 266 3e-69 ref|YP_001352833.1| uroporphyrinogen-III synthase [Janthinobacte... 243 2e-62 ref|YP_001099317.1| uroporphyrinogen III synthase [Herminiimonas... 227 1e-57 ref|ZP_08273543.1| uroporphyrinogen III synthase [Oxalobacterace... 213 2e-53 >ref|YP_004752066.1| uroporphyrinogen III synthase [Collimonas fungivorans Ter331] gb|AEK61243.1| uroporphyrinogen III synthase [Collimonas fungivorans Ter331] Length = 271 Score = 266 bits (679), Expect = 3e-69, Method: Compositional matrix adjust. Identities = 137/255 (53%), Positives = 183/255 (71%) Query: 5 ASRPVVITRPLAQAGAFATQVTAIGRMPVIFPLLEIAPVADSTELRRVLSVLERYALVVF 64 A RPV+ITRPL QA A A Q+ A GR PV+FPLLEI P+ D+ L+ VL L +ALVVF Sbjct: 16 ALRPVIITRPLQQASALARQIAARGRQPVVFPLLEILPLNDNAPLQAVLGELADFALVVF 75 Query: 65 VSPNAIDAAFQFIASWPQAVAIGIVGEGSRLALRRHGVDDAHATIHAPRNSARMDSEELF 124 VSPNAIDAAF+ IA WP+ + IGIVGEGSR AL RHG+ + TI +P + AR DSE L Sbjct: 76 VSPNAIDAAFRHIAGWPRQLPIGIVGEGSRAALARHGLTAHNTTIFSPPDPARTDSEGLL 135 Query: 125 KALDPEALHGKRVLIVRGQAGRDFLTDMLRDRQVEVEHVTAYQRLLPQIDAEKAAHLRSL 184 +ALD ++L G++VL+VRG++GR+F D L ++V+ V AY+R P +DA L+ L Sbjct: 136 QALDLDSLRGRQVLLVRGESGREFFADSLLAAGIKVQAVAAYRRQAPVLDASLRTRLQFL 195 Query: 185 IEAGSEWVVTSSEALRNLRQITADALGQDCVVKLQRNEIIVSHQRIAETAHSLGFSHVTV 244 ++ ++W++TSSEALR+L + G V K+Q+ +++V H RIAETAH+LGF+ VT+ Sbjct: 196 LDTENDWILTSSEALRHLVDLVQALAGGAGVAKIQQQKLLVPHARIAETAHTLGFTDVTL 255 Query: 245 TGSGDERLIAALQSP 259 TGSGDERL+ ALQ P Sbjct: 256 TGSGDERLLDALQFP 270 >ref|YP_003776320.1| uroporphyrinogen-III synthase [Herbaspirillum seropedicae SmR1] gb|ADJ64412.1| uroporphyrinogen-III synthase protein [Herbaspirillum seropedicae SmR1] Length = 269 Score = 266 bits (679), Expect = 3e-69, Method: Compositional matrix adjust. Identities = 145/250 (58%), Positives = 183/250 (73%), Gaps = 3/250 (1%) Query: 5 ASRPVVITRPLAQAGAFATQVTAIGRMPVIFPLLEIAPVADSTELRRVLSVLERYALVVF 64 A+ PVV+TRP QA AFA V A+GR V+FPLLEI+ V D L+ +L+ LE +ALVVF Sbjct: 9 AALPVVVTRPRQQAHAFAASVQALGRPAVVFPLLEISAVEDVATLQAMLARLEEFALVVF 68 Query: 65 VSPNAIDAAFQFIAS---WPQAVAIGIVGEGSRLALRRHGVDDAHATIHAPRNSARMDSE 121 VSPNAIDAAF + + WP VAIGIVGEGSRLALR HGVD A AT++ P+ + +MDSE Sbjct: 69 VSPNAIDAAFAQLPAGRPWPAKVAIGIVGEGSRLALRAHGVDAACATLYGPQRADKMDSE 128 Query: 122 ELFKALDPEALHGKRVLIVRGQAGRDFLTDMLRDRQVEVEHVTAYQRLLPQIDAEKAAHL 181 EL K+L L G+R LIVRGQ+GRDFL++ L+ + V VE++TAY+R P++DA+ L Sbjct: 129 ELLKSLPLAQLRGQRALIVRGQSGRDFLSEALQQQGVTVEYLTAYRRTAPRLDAQNGPLL 188 Query: 182 RSLIEAGSEWVVTSSEALRNLRQITADALGQDCVVKLQRNEIIVSHQRIAETAHSLGFSH 241 L++ G++WV+TSSEALRNL +T A G++ VVKLQR I VSH RIAETA GF Sbjct: 189 LDLLDGGADWVITSSEALRNLVDLTRLAGGEERVVKLQRQRIFVSHHRIAETAREQGFER 248 Query: 242 VTVTGSGDER 251 V +TGSGDER Sbjct: 249 VVLTGSGDER 258 >ref|YP_001352833.1| uroporphyrinogen-III synthase [Janthinobacterium sp. Marseille] gb|ABR90255.1| uroporphyrinogen-III synthase [Janthinobacterium sp. Marseille] Length = 256 Score = 243 bits (620), Expect = 2e-62, Method: Compositional matrix adjust. Identities = 127/250 (50%), Positives = 168/250 (67%) Query: 9 VVITRPLAQAGAFATQVTAIGRMPVIFPLLEIAPVADSTELRRVLSVLERYALVVFVSPN 68 VVITRPLAQA A A +VT +GR VIFPLLEI P+ D LR+ L L++YAL+ FVSPN Sbjct: 5 VVITRPLAQADALAQRVTELGRKAVIFPLLEILPLDDQQSLRQALRELDQYALIAFVSPN 64 Query: 69 AIDAAFQFIASWPQAVAIGIVGEGSRLALRRHGVDDAHATIHAPRNSARMDSEELFKALD 128 AIDAAF WP + + +VGEGSR+AL RHG ++TI +P + R DS+ L LD Sbjct: 65 AIDAAFNARPDWPWQIPLAVVGEGSRMALLRHGATTGNSTIISPTDLERTDSQTLLAELD 124 Query: 129 PEALHGKRVLIVRGQAGRDFLTDMLRDRQVEVEHVTAYQRLLPQIDAEKAAHLRSLIEAG 188 L GK+VLI+RG+ GR+ L D LR V V + AY+R+ P+++ + L+ L+ Sbjct: 125 LPVLRGKQVLIIRGETGRELLGDTLRAAGVGVTPLAAYRRVAPELNNARRGELKRLLSCQ 184 Query: 189 SEWVVTSSEALRNLRQITADALGQDCVVKLQRNEIIVSHQRIAETAHSLGFSHVTVTGSG 248 ++W+VTSSE LR L ++ A V K+Q+ IIVSH RIAETA LGFS++T+T SG Sbjct: 185 NDWIVTSSEGLRFLTEMVAQLDEAGSVAKMQQQRIIVSHVRIAETAQLLGFSNITLTRSG 244 Query: 249 DERLIAALQS 258 D+ L+AALQS Sbjct: 245 DDGLLAALQS 254 >ref|YP_001099317.1| uroporphyrinogen III synthase [Herminiimonas arsenicoxydans] emb|CAL61190.1| uroporphyrinogen III synthase (UROS) (Uroporphyrinogen-III cosynthetase) (Hydroxymethylbilane hydrolyase [cyclizing]) [Herminiimonas arsenicoxydans] Length = 260 Score = 227 bits (579), Expect = 1e-57, Method: Compositional matrix adjust. Identities = 128/250 (51%), Positives = 168/250 (67%) Query: 9 VVITRPLAQAGAFATQVTAIGRMPVIFPLLEIAPVADSTELRRVLSVLERYALVVFVSPN 68 VVITRPLAQA A +VTA+GR +FPLL+I P+AD L++ L L YAL+ FVSPN Sbjct: 9 VVITRPLAQAEGLARRVTALGRKATVFPLLDILPLADQASLQQALRDLSGYALIAFVSPN 68 Query: 69 AIDAAFQFIASWPQAVAIGIVGEGSRLALRRHGVDDAHATIHAPRNSARMDSEELFKALD 128 AIDAA A WP+ + + +VGEGSRLAL RHG+ ++TI +P + R DSE L LD Sbjct: 69 AIDAALAARADWPRDIPMAVVGEGSRLALARHGLTAENSTIISPTDLDRTDSETLLAELD 128 Query: 129 PEALHGKRVLIVRGQAGRDFLTDMLRDRQVEVEHVTAYQRLLPQIDAEKAAHLRSLIEAG 188 AL K++LIVRG+ GR L++ LR +V + AY+R+ P DA + L+ L+ Sbjct: 129 LPALRNKQILIVRGETGRPLLSEALRAAGAQVTLLAAYRRVAPVFDATRRRELKRLLHGQ 188 Query: 189 SEWVVTSSEALRNLRQITADALGQDCVVKLQRNEIIVSHQRIAETAHSLGFSHVTVTGSG 248 ++W+VTSSEALR L Q+ A + V K+Q+ IIVSH RI ETA LGFS++TVT SG Sbjct: 189 NDWIVTSSEALRFLMQMVAQLDEAEGVAKMQQQRIIVSHIRIGETAQLLGFSNITVTRSG 248 Query: 249 DERLIAALQS 258 D+ L+AALQS Sbjct: 249 DDGLLAALQS 258 >ref|ZP_08273543.1| uroporphyrinogen III synthase [Oxalobacteraceae bacterium IMCC9480] gb|EGF32979.1| uroporphyrinogen III synthase [Oxalobacteraceae bacterium IMCC9480] Length = 256 Score = 213 bits (542), Expect = 2e-53, Method: Compositional matrix adjust. Identities = 126/253 (49%), Positives = 166/253 (65%) Query: 6 SRPVVITRPLAQAGAFATQVTAIGRMPVIFPLLEIAPVADSTELRRVLSVLERYALVVFV 65 +RP+VITRPLAQ+ A A Q+ R VI PLLEI P+ D++ L+ VL+ LE +ALV FV Sbjct: 2 ARPLVITRPLAQSLALAQQLRDGDRELVILPLLEILPLPDTSALQAVLAQLESFALVAFV 61 Query: 66 SPNAIDAAFQFIASWPQAVAIGIVGEGSRLALRRHGVDDAHATIHAPRNSARMDSEELFK 125 SPNAIDA F +A WP +V + ++GEGSR AL RHGV I +P ++ R DS+ L + Sbjct: 62 SPNAIDATFAQLACWPPSVPLAVMGEGSRRALARHGVAAGLYQITSPLDTQRTDSQTLLE 121 Query: 126 ALDPEALHGKRVLIVRGQAGRDFLTDMLRDRQVEVEHVTAYQRLLPQIDAEKAAHLRSLI 185 ALD L G++VLIVRG++GR+ L D LRD + V+ V AY+R P +D L L+ Sbjct: 122 ALDLSRLQGRQVLIVRGESGRELLADALRDAGISVQQVAAYRRAAPLLDDALRQRLTDLL 181 Query: 186 EAGSEWVVTSSEALRNLRQITADALGQDCVVKLQRNEIIVSHQRIAETAHSLGFSHVTVT 245 +WV+TSSEAL+ L + V K+QR ++ V H+RIAETA SLGF V +T Sbjct: 182 AQEGDWVITSSEALQVLMHFVQQVDAESGVDKIQRMKLFVPHRRIAETALSLGFRSVCLT 241 Query: 246 GSGDERLIAALQS 258 GSGDE L+ ALQS Sbjct: 242 GSGDEGLLTALQS 254