BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0025.0043.p (356 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003776686.1| 3-isopropylmalate dehydrogenase oxidoreducta... 681 0.0 ref|YP_727069.1| 3-isopropylmalate dehydrogenase [Ralstonia eutr... 664 0.0 ref|YP_004686301.1| 3-isopropylmalate dehydrogenase LeuB [Cupria... 662 0.0 ref|YP_584618.1| 3-isopropylmalate dehydrogenase [Cupriavidus me... 660 0.0 ref|YP_296517.1| 3-isopropylmalate dehydrogenase [Ralstonia eutr... 658 0.0 >ref|YP_003776686.1| 3-isopropylmalate dehydrogenase oxidoreductase [Herbaspirillum seropedicae SmR1] emb|CAM32595.1| 3-isopropylmalate dehydrogenase oxidoreductase protein [Herbaspirillum seropedicae] gb|ADJ64778.1| 3-isopropylmalate dehydrogenase oxidoreductase protein [Herbaspirillum seropedicae SmR1] Length = 356 Score = 681 bits (1758), Expect = 0.0, Method: Compositional matrix adjust. Identities = 331/355 (93%), Positives = 341/355 (96%) Query: 1 MKIAILPGDGIGPEIIEQAVRVLNTLGEKFEMETAPVGGAGYEAHGHPLPDGTLKLAKES 60 MKIAILPGDGIGPEI+ +AVRVLN L EKFEMETAPVGGAGYEAHGHPLPDGTLKLAKE+ Sbjct: 1 MKIAILPGDGIGPEIVNEAVRVLNALDEKFEMETAPVGGAGYEAHGHPLPDGTLKLAKEA 60 Query: 61 DAILFGAVGDWKYDTLDRPLRPEQAILGLRKHLQLFANFRPAICYPELTGASSLKPELVA 120 DAILFGAVGDWKYD L+R LRPEQAILGLRKHLQLFANFRPAICYPELTGASSLKPELVA Sbjct: 61 DAILFGAVGDWKYDKLERALRPEQAILGLRKHLQLFANFRPAICYPELTGASSLKPELVA 120 Query: 121 GLDILIVRELNGDIYFGQPRGMREAPDGPFKGAREGFDTMRYSEPEIRRIAHVAFQAAAK 180 LDILIVRELNGDIYFGQPRGMREAPDGPFKGAREGFDTMRYSEPEIRRIAHVAFQAAAK Sbjct: 121 NLDILIVRELNGDIYFGQPRGMREAPDGPFKGAREGFDTMRYSEPEIRRIAHVAFQAAAK 180 Query: 181 RGNRLCSVDKANVLETFQFWKDIVTDVHKEYPQVELTHMYVDNAAMQLVKAPKNFDVIVT 240 RG RLCSVDKANVLETFQFWKDIVT+V KEYP VEL+HMYVDNAAMQLVKAPKNFDVIVT Sbjct: 181 RGKRLCSVDKANVLETFQFWKDIVTEVGKEYPDVELSHMYVDNAAMQLVKAPKNFDVIVT 240 Query: 241 GNMFGDILSDAAAMLTGSIGMLPSASLDANNKGLYEPSHGSAPDIAGKGIANPLATILSA 300 GNMFGDILSDAAAMLTGSIGMLPSASLDANNKGLYEPSHGSAPDIAG+GIANPLATILSA Sbjct: 241 GNMFGDILSDAAAMLTGSIGMLPSASLDANNKGLYEPSHGSAPDIAGRGIANPLATILSA 300 Query: 301 AMMLRFSLNKAEQADRIEAAVKKVLAQGYRTGDIYEEGTTKVGTKEMGDAVVKAL 355 AMMLRFSLNKAEQADRIE AVKKVLAQG RT DIYEEG TKV T++MG+AVVKAL Sbjct: 301 AMMLRFSLNKAEQADRIENAVKKVLAQGLRTADIYEEGCTKVNTQQMGEAVVKAL 355 >ref|YP_727069.1| 3-isopropylmalate dehydrogenase [Ralstonia eutropha H16] emb|CAJ93701.1| 3-Isopropylmalate dehydrogenase [Ralstonia eutropha H16] Length = 355 Score = 664 bits (1712), Expect = 0.0, Method: Compositional matrix adjust. Identities = 319/355 (89%), Positives = 339/355 (95%) Query: 1 MKIAILPGDGIGPEIIEQAVRVLNTLGEKFEMETAPVGGAGYEAHGHPLPDGTLKLAKES 60 MKIA+LPGDGIGPEI+ +AV+VLN L EKFE+ETAPVGGAGYEA GHPLP+ TLKLAKE+ Sbjct: 1 MKIAVLPGDGIGPEIVAEAVKVLNALDEKFELETAPVGGAGYEAEGHPLPENTLKLAKEA 60 Query: 61 DAILFGAVGDWKYDTLDRPLRPEQAILGLRKHLQLFANFRPAICYPELTGASSLKPELVA 120 DAILFGAVGDWKYD+LDRPLRPEQAILGLRKHLQLFANFRPAICYPELTGASSLKPELVA Sbjct: 61 DAILFGAVGDWKYDSLDRPLRPEQAILGLRKHLQLFANFRPAICYPELTGASSLKPELVA 120 Query: 121 GLDILIVRELNGDIYFGQPRGMREAPDGPFKGAREGFDTMRYSEPEIRRIAHVAFQAAAK 180 GLDILIVRELNGDIYFGQPRG+REAPDG FKGAREGFDTMRYSEPEIRRIAHVAFQAAAK Sbjct: 121 GLDILIVRELNGDIYFGQPRGVREAPDGLFKGAREGFDTMRYSEPEIRRIAHVAFQAAAK 180 Query: 181 RGNRLCSVDKANVLETFQFWKDIVTDVHKEYPQVELTHMYVDNAAMQLVKAPKNFDVIVT 240 RG +LCSVDKANVLETFQFWKDIV +VHKEYP+VEL+HMYVDNAAMQLVKAPK+FDVIVT Sbjct: 181 RGKKLCSVDKANVLETFQFWKDIVIEVHKEYPEVELSHMYVDNAAMQLVKAPKSFDVIVT 240 Query: 241 GNMFGDILSDAAAMLTGSIGMLPSASLDANNKGLYEPSHGSAPDIAGKGIANPLATILSA 300 GNMFGDILSD AAMLTGSIGMLPSASLDANNKGLYEPSHGSAPDIAGKG+ANPLATILSA Sbjct: 241 GNMFGDILSDEAAMLTGSIGMLPSASLDANNKGLYEPSHGSAPDIAGKGVANPLATILSA 300 Query: 301 AMMLRFSLNKAEQADRIEAAVKKVLAQGYRTGDIYEEGTTKVGTKEMGDAVVKAL 355 AMMLR+SLN+AEQADRIE AVKKVLAQGYRTGDI G +VGT+EMGDAV+ AL Sbjct: 301 AMMLRYSLNRAEQADRIENAVKKVLAQGYRTGDILTPGCKQVGTREMGDAVLAAL 355 >ref|YP_004686301.1| 3-isopropylmalate dehydrogenase LeuB [Cupriavidus necator N-1] gb|AEI77820.1| 3-isopropylmalate dehydrogenase LeuB [Cupriavidus necator N-1] Length = 355 Score = 662 bits (1708), Expect = 0.0, Method: Compositional matrix adjust. Identities = 319/355 (89%), Positives = 339/355 (95%) Query: 1 MKIAILPGDGIGPEIIEQAVRVLNTLGEKFEMETAPVGGAGYEAHGHPLPDGTLKLAKES 60 MKIA+LPGDGIGPEII +AV+VLN L EKFE+ETAPVGGAGYEA GHPLP+ TLKLAKE+ Sbjct: 1 MKIAVLPGDGIGPEIIAEAVKVLNALDEKFELETAPVGGAGYEAEGHPLPENTLKLAKEA 60 Query: 61 DAILFGAVGDWKYDTLDRPLRPEQAILGLRKHLQLFANFRPAICYPELTGASSLKPELVA 120 DAILFGAVGDWKYD+L+RPLRPEQAILGLRKHLQLFANFRPAICYPELTGASSLKPELVA Sbjct: 61 DAILFGAVGDWKYDSLERPLRPEQAILGLRKHLQLFANFRPAICYPELTGASSLKPELVA 120 Query: 121 GLDILIVRELNGDIYFGQPRGMREAPDGPFKGAREGFDTMRYSEPEIRRIAHVAFQAAAK 180 GLDILIVRELNGDIYFGQPRG+REAPDG FKGAREGFDTMRYSEPEIRRIAHVAFQAAAK Sbjct: 121 GLDILIVRELNGDIYFGQPRGVREAPDGLFKGAREGFDTMRYSEPEIRRIAHVAFQAAAK 180 Query: 181 RGNRLCSVDKANVLETFQFWKDIVTDVHKEYPQVELTHMYVDNAAMQLVKAPKNFDVIVT 240 RG +LCSVDKANVLETFQFWKDIV +VHKEYP+VEL+HMYVDNAAMQLVKAPK+FDVIVT Sbjct: 181 RGKKLCSVDKANVLETFQFWKDIVIEVHKEYPEVELSHMYVDNAAMQLVKAPKSFDVIVT 240 Query: 241 GNMFGDILSDAAAMLTGSIGMLPSASLDANNKGLYEPSHGSAPDIAGKGIANPLATILSA 300 GNMFGDILSD AAMLTGSIGMLPSASLDANNKGLYEPSHGSAPDIAGKG+ANPLATILSA Sbjct: 241 GNMFGDILSDEAAMLTGSIGMLPSASLDANNKGLYEPSHGSAPDIAGKGVANPLATILSA 300 Query: 301 AMMLRFSLNKAEQADRIEAAVKKVLAQGYRTGDIYEEGTTKVGTKEMGDAVVKAL 355 AMMLR+SLN+AEQADRIE AVKKVLAQGYRTGDI G +VGT+EMGDAV+ AL Sbjct: 301 AMMLRYSLNRAEQADRIENAVKKVLAQGYRTGDILTPGCKQVGTREMGDAVLAAL 355 >ref|YP_584618.1| 3-isopropylmalate dehydrogenase [Cupriavidus metallidurans CH34] sp|Q1LKH7.1|LEU3_RALME RecName: Full=3-isopropylmalate dehydrogenase; AltName: Full=3-IPM-DH; AltName: Full=Beta-IPM dehydrogenase; Short=IMDH gb|ABF09349.1| 3-isopropylmalate dehydrogenase [Cupriavidus metallidurans CH34] Length = 355 Score = 660 bits (1704), Expect = 0.0, Method: Compositional matrix adjust. Identities = 318/355 (89%), Positives = 336/355 (94%) Query: 1 MKIAILPGDGIGPEIIEQAVRVLNTLGEKFEMETAPVGGAGYEAHGHPLPDGTLKLAKES 60 MKIA+LPGDGIGPEI+ +AV+VLN L EKFEMETAPVGGAGYEA GHPLPD TLKLAKE+ Sbjct: 1 MKIAVLPGDGIGPEIVAEAVKVLNALDEKFEMETAPVGGAGYEAEGHPLPDNTLKLAKEA 60 Query: 61 DAILFGAVGDWKYDTLDRPLRPEQAILGLRKHLQLFANFRPAICYPELTGASSLKPELVA 120 DAILFGAVGDWKYD+LDRPLRPEQAILGLRKHLQLFANFRPAICYPELTGASSLKPELVA Sbjct: 61 DAILFGAVGDWKYDSLDRPLRPEQAILGLRKHLQLFANFRPAICYPELTGASSLKPELVA 120 Query: 121 GLDILIVRELNGDIYFGQPRGMREAPDGPFKGAREGFDTMRYSEPEIRRIAHVAFQAAAK 180 GLDILIVRELNGDIYFGQPRG+REAPDG FKGAREGFDTMRYSEPE+RRIAHVAFQAAAK Sbjct: 121 GLDILIVRELNGDIYFGQPRGVREAPDGLFKGAREGFDTMRYSEPEVRRIAHVAFQAAAK 180 Query: 181 RGNRLCSVDKANVLETFQFWKDIVTDVHKEYPQVELTHMYVDNAAMQLVKAPKNFDVIVT 240 RG +LCSVDKANVLETFQFWKDIV DV KEYP VEL+HMYVDNAAMQLVKAPK+FDVIVT Sbjct: 181 RGKKLCSVDKANVLETFQFWKDIVIDVSKEYPDVELSHMYVDNAAMQLVKAPKSFDVIVT 240 Query: 241 GNMFGDILSDAAAMLTGSIGMLPSASLDANNKGLYEPSHGSAPDIAGKGIANPLATILSA 300 GNMFGDILSD AAMLTGSIGMLPSASLDANNKGLYEPSHGSAPDIAGKG+ANPLATILSA Sbjct: 241 GNMFGDILSDEAAMLTGSIGMLPSASLDANNKGLYEPSHGSAPDIAGKGVANPLATILSA 300 Query: 301 AMMLRFSLNKAEQADRIEAAVKKVLAQGYRTGDIYEEGTTKVGTKEMGDAVVKAL 355 AMMLR+SLN+AEQADRIE AVKKVLAQGYRT DI G +VGT+EMG+AV+ AL Sbjct: 301 AMMLRYSLNRAEQADRIENAVKKVLAQGYRTADIVTPGCKQVGTREMGEAVLAAL 355 >ref|YP_296517.1| 3-isopropylmalate dehydrogenase [Ralstonia eutropha JMP134] sp|Q46YW0.1|LEU3_RALEJ RecName: Full=3-isopropylmalate dehydrogenase; AltName: Full=3-IPM-DH; AltName: Full=Beta-IPM dehydrogenase; Short=IMDH gb|AAZ61673.1| 3-isopropylmalate dehydrogenase [Ralstonia eutropha JMP134] Length = 355 Score = 658 bits (1697), Expect = 0.0, Method: Compositional matrix adjust. Identities = 318/355 (89%), Positives = 336/355 (94%) Query: 1 MKIAILPGDGIGPEIIEQAVRVLNTLGEKFEMETAPVGGAGYEAHGHPLPDGTLKLAKES 60 MKIA+LPGDGIGPEI+ +AV+VLN L EKFEMETAPVGGAGYEA GHPLP+ TLKLAKE+ Sbjct: 1 MKIAVLPGDGIGPEIVAEAVKVLNALDEKFEMETAPVGGAGYEAEGHPLPENTLKLAKEA 60 Query: 61 DAILFGAVGDWKYDTLDRPLRPEQAILGLRKHLQLFANFRPAICYPELTGASSLKPELVA 120 DAILFGAVGDWKYD+L+R LRPEQAILGLRKHLQLFANFRPAICYPELTGASSLKPELVA Sbjct: 61 DAILFGAVGDWKYDSLERALRPEQAILGLRKHLQLFANFRPAICYPELTGASSLKPELVA 120 Query: 121 GLDILIVRELNGDIYFGQPRGMREAPDGPFKGAREGFDTMRYSEPEIRRIAHVAFQAAAK 180 GLDILIVRELNGDIYFGQPRG+REAPDG FKGAREGFDTMRYSEPEIRRIAHVAFQAAAK Sbjct: 121 GLDILIVRELNGDIYFGQPRGVREAPDGLFKGAREGFDTMRYSEPEIRRIAHVAFQAAAK 180 Query: 181 RGNRLCSVDKANVLETFQFWKDIVTDVHKEYPQVELTHMYVDNAAMQLVKAPKNFDVIVT 240 RG +LCSVDKANVLETFQFWKDIV DV KEYP VEL+HMYVDNAAMQLVKAPK+FDVIVT Sbjct: 181 RGKKLCSVDKANVLETFQFWKDIVIDVSKEYPDVELSHMYVDNAAMQLVKAPKSFDVIVT 240 Query: 241 GNMFGDILSDAAAMLTGSIGMLPSASLDANNKGLYEPSHGSAPDIAGKGIANPLATILSA 300 GNMFGDILSD AAMLTGSIGMLPSASLDANNKGLYEPSHGSAPDIAGKG+ANPLATILSA Sbjct: 241 GNMFGDILSDEAAMLTGSIGMLPSASLDANNKGLYEPSHGSAPDIAGKGVANPLATILSA 300 Query: 301 AMMLRFSLNKAEQADRIEAAVKKVLAQGYRTGDIYEEGTTKVGTKEMGDAVVKAL 355 AMMLR+SLNKAEQADRIE AVKKVLAQGYRTGDI G +VGT+EMG+AV+ AL Sbjct: 301 AMMLRYSLNKAEQADRIENAVKKVLAQGYRTGDILTPGCKQVGTREMGEAVLAAL 355