BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0025.0040.p (466 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003776688.1| 3-isopropylmalate dehydratase large subunit ... 901 0.0 ref|YP_004752521.1| 3-isopropylmalate dehydratase large subunit ... 894 0.0 ref|YP_001353862.1| 3-isopropylmalate dehydratase large subunit ... 878 0.0 ref|YP_001099519.1| isopropylmalate isomerase large subunit [Her... 867 0.0 ref|ZP_08272573.1| 3-isopropylmalate dehydratase large subunit [... 853 0.0 >ref|YP_003776688.1| 3-isopropylmalate dehydratase large subunit [Herbaspirillum seropedicae SmR1] gb|ADJ64780.1| 3-isopropylmalate dehydratase (large subunit) protein [Herbaspirillum seropedicae SmR1] Length = 466 Score = 901 bits (2329), Expect = 0.0, Method: Compositional matrix adjust. Identities = 439/466 (94%), Positives = 455/466 (97%) Query: 1 MLKTLYDKLWESHVVHAEQDGTAILYIDRHLLHEVTSPQAFEGLKLAGRQPWRNAANLVV 60 MLKTLYDKLWESHVVH E DGTAILYIDRHLLHEVTSPQAFEGLKLAGRQPWRN+ANL+V Sbjct: 1 MLKTLYDKLWESHVVHTEDDGTAILYIDRHLLHEVTSPQAFEGLKLAGRQPWRNSANLMV 60 Query: 61 ADHNVPTTNRANGIADPISRLQVETLDANAKEYGLTYFGMNDKRQGIVHVIGPEQGATLP 120 ADHNVPTT+RA+GIADPISRLQVETLD NAKEY LTYFGMNDKRQGIVHVIGPEQGATLP Sbjct: 61 ADHNVPTTDRAHGIADPISRLQVETLDGNAKEYSLTYFGMNDKRQGIVHVIGPEQGATLP 120 Query: 121 GMTVVCGDSHTSTHGAFACLAHGIGTSEVEHVLATQTLLAKKSKSMLVQVDGALPNGVTA 180 GMTVVCGDSHTSTHGAFA LAHGIGTSEVEHVLATQTLLA+KSK+MLVQVDGALP GVTA Sbjct: 121 GMTVVCGDSHTSTHGAFAALAHGIGTSEVEHVLATQTLLARKSKAMLVQVDGALPAGVTA 180 Query: 181 KDIVLAVIGKIGTAGGTGYAIEFAGSTMRALTMEGRMTVCNMAIEAGARAGMIAVDDTTI 240 KDIVLAVIGKIGTAGGTGYAIEFAGST+R+L+MEGRMTVCNMAIEAGARAGM+A DDTT+ Sbjct: 181 KDIVLAVIGKIGTAGGTGYAIEFAGSTIRSLSMEGRMTVCNMAIEAGARAGMVAFDDTTL 240 Query: 241 NYLKGRPFSPAGPHWERAVSYWRTLHSDPGAKFDMVVTLNATEIKPQVTWGTSPEMVIAI 300 YLKGRPFSP+GPHWERAVSYWR+LHSDPGAKFDMVVTLNA EIKPQVTWGTSPEMV+A+ Sbjct: 241 EYLKGRPFSPSGPHWERAVSYWRSLHSDPGAKFDMVVTLNAAEIKPQVTWGTSPEMVVAV 300 Query: 301 DSRVPDPDKEKDATKRDGMEKALAYMALKPNTPIEDIRIDKVFIGSCTNSRIEDLREAAA 360 D+RVPDPDKEKD TKRDGMEKALAYMALKPNTPIEDIRIDKVFIGSCTNSRIEDLREAA Sbjct: 301 DARVPDPDKEKDPTKRDGMEKALAYMALKPNTPIEDIRIDKVFIGSCTNSRIEDLREAAK 360 Query: 361 VVRGKFRASNVKLAMVVPGSGLVKEQAEREGLDKIFRDAGFEWREPGCSMCLAMNADRLE 420 VVRGKFRASNVKLAMVVPGSGLVKEQAEREGLDKIFRDAGFEWREPGCSMCLAMNADRLE Sbjct: 361 VVRGKFRASNVKLAMVVPGSGLVKEQAEREGLDKIFRDAGFEWREPGCSMCLAMNADRLE 420 Query: 421 PGERCASTSNRNFEGRQGAGGRTHLVSPAMAAAAGIAGHFVDVRSL 466 PGERCASTSNRNFEGRQGAGGRTHLVSPAMAAAAGIAGHFVDVRSL Sbjct: 421 PGERCASTSNRNFEGRQGAGGRTHLVSPAMAAAAGIAGHFVDVRSL 466 >ref|YP_004752521.1| 3-isopropylmalate dehydratase large subunit [Collimonas fungivorans Ter331] gb|AEK61698.1| 3-isopropylmalate dehydratase large subunit [Collimonas fungivorans Ter331] Length = 466 Score = 894 bits (2310), Expect = 0.0, Method: Compositional matrix adjust. Identities = 437/466 (93%), Positives = 450/466 (96%) Query: 1 MLKTLYDKLWESHVVHAEQDGTAILYIDRHLLHEVTSPQAFEGLKLAGRQPWRNAANLVV 60 MLKTLYDKLWESHVVH EQDGTAILYIDRHLLHEVTSPQAFEGLKLAGR+PWR AANL+V Sbjct: 1 MLKTLYDKLWESHVVHTEQDGTAILYIDRHLLHEVTSPQAFEGLKLAGRKPWRQAANLMV 60 Query: 61 ADHNVPTTNRANGIADPISRLQVETLDANAKEYGLTYFGMNDKRQGIVHVIGPEQGATLP 120 ADHNVPTT RANGIADPISRLQVETLDANAK Y LTYFGMND RQGIVHVIGPEQGATLP Sbjct: 61 ADHNVPTTGRANGIADPISRLQVETLDANAKSYDLTYFGMNDHRQGIVHVIGPEQGATLP 120 Query: 121 GMTVVCGDSHTSTHGAFACLAHGIGTSEVEHVLATQTLLAKKSKSMLVQVDGALPNGVTA 180 GMTVVCGDSHTSTHGAF CLAHGIGTSEVEHVLATQTLL KKSKSMLVQVDGA+P GVTA Sbjct: 121 GMTVVCGDSHTSTHGAFGCLAHGIGTSEVEHVLATQTLLTKKSKSMLVQVDGAIPAGVTA 180 Query: 181 KDIVLAVIGKIGTAGGTGYAIEFAGSTMRALTMEGRMTVCNMAIEAGARAGMIAVDDTTI 240 KDIVLAVIG+IGTAGGTGYAIEFAGS +RAL+MEGRMTVCNMAIEAGARAGMIAVDDTT+ Sbjct: 181 KDIVLAVIGRIGTAGGTGYAIEFAGSAIRALSMEGRMTVCNMAIEAGARAGMIAVDDTTL 240 Query: 241 NYLKGRPFSPAGPHWERAVSYWRTLHSDPGAKFDMVVTLNATEIKPQVTWGTSPEMVIAI 300 NY+KGRPFSPAGPHWERAV+YWRTLHSD GAKFDMVVTL A EIKPQVTWGTSPEMV+A+ Sbjct: 241 NYVKGRPFSPAGPHWERAVTYWRTLHSDQGAKFDMVVTLGAAEIKPQVTWGTSPEMVVAV 300 Query: 301 DSRVPDPDKEKDATKRDGMEKALAYMALKPNTPIEDIRIDKVFIGSCTNSRIEDLREAAA 360 D RVPDPDKEKDATKRDGMEKALAYMALKPNT IEDIRIDKVFIGSCTNSRIEDLR AAA Sbjct: 301 DGRVPDPDKEKDATKRDGMEKALAYMALKPNTAIEDIRIDKVFIGSCTNSRIEDLRAAAA 360 Query: 361 VVRGKFRASNVKLAMVVPGSGLVKEQAEREGLDKIFRDAGFEWREPGCSMCLAMNADRLE 420 VVRGKFRASNVKLAMVVPGSGLVKEQAEREGLDKIF+DAGFEWREPGCSMCLAMNADRLE Sbjct: 361 VVRGKFRASNVKLAMVVPGSGLVKEQAEREGLDKIFKDAGFEWREPGCSMCLAMNADRLE 420 Query: 421 PGERCASTSNRNFEGRQGAGGRTHLVSPAMAAAAGIAGHFVDVRSL 466 PGERCASTSNRNFEGRQGAGGRTHLVSPAMAAAAGIAGHFVD+RSL Sbjct: 421 PGERCASTSNRNFEGRQGAGGRTHLVSPAMAAAAGIAGHFVDIRSL 466 >ref|YP_001353862.1| 3-isopropylmalate dehydratase large subunit [Janthinobacterium sp. Marseille] sp|A6T015.1|LEUC_JANMA RecName: Full=3-isopropylmalate dehydratase large subunit; AltName: Full=Alpha-IPM isomerase; Short=IPMI; AltName: Full=Isopropylmalate isomerase gb|ABR88947.1| 3-isopropylmalate dehydratase large subunit [Janthinobacterium sp. Marseille] Length = 468 Score = 878 bits (2268), Expect = 0.0, Method: Compositional matrix adjust. Identities = 416/466 (89%), Positives = 440/466 (94%) Query: 1 MLKTLYDKLWESHVVHAEQDGTAILYIDRHLLHEVTSPQAFEGLKLAGRQPWRNAANLVV 60 M +TLYDKLW+SHVV DGT +LYIDRHLLHEVTSPQAFEGLKLAGR+PWR +ANL+V Sbjct: 1 MAQTLYDKLWQSHVVETGDDGTTVLYIDRHLLHEVTSPQAFEGLKLAGRRPWRVSANLMV 60 Query: 61 ADHNVPTTNRANGIADPISRLQVETLDANAKEYGLTYFGMNDKRQGIVHVIGPEQGATLP 120 ADHNVPTT+RANGIADP SRLQVETLD NA EYGLTYF M DKRQGIVHVIGPEQGATLP Sbjct: 61 ADHNVPTTDRANGIADPTSRLQVETLDGNAHEYGLTYFSMRDKRQGIVHVIGPEQGATLP 120 Query: 121 GMTVVCGDSHTSTHGAFACLAHGIGTSEVEHVLATQTLLAKKSKSMLVQVDGALPNGVTA 180 GMTVVCGDSHTSTHGAF CLAHGIGTSEVEHVLATQTLLA+KSK+MLVQVDGALP+GVTA Sbjct: 121 GMTVVCGDSHTSTHGAFGCLAHGIGTSEVEHVLATQTLLAQKSKAMLVQVDGALPDGVTA 180 Query: 181 KDIVLAVIGKIGTAGGTGYAIEFAGSTMRALTMEGRMTVCNMAIEAGARAGMIAVDDTTI 240 KDIVLAVIGKIGTAGGTGYAIEFAGST+R+L+MEGRMT+CNMAIEAGARAGM+AVDD TI Sbjct: 181 KDIVLAVIGKIGTAGGTGYAIEFAGSTIRSLSMEGRMTICNMAIEAGARAGMVAVDDITI 240 Query: 241 NYLKGRPFSPAGPHWERAVSYWRTLHSDPGAKFDMVVTLNATEIKPQVTWGTSPEMVIAI 300 NY+KGRP SP GPHW+RAV YWRTLHSD GAKFD+VVTLNA EIKPQV+WGTSPEMV+A+ Sbjct: 241 NYVKGRPLSPVGPHWDRAVEYWRTLHSDAGAKFDLVVTLNAAEIKPQVSWGTSPEMVVAV 300 Query: 301 DSRVPDPDKEKDATKRDGMEKALAYMALKPNTPIEDIRIDKVFIGSCTNSRIEDLREAAA 360 D RVPDPDKEKD TKRDGMEKAL YMALKPNTPI DIRIDKVFIGSCTNSRIEDLR AAA Sbjct: 301 DGRVPDPDKEKDPTKRDGMEKALIYMALKPNTPITDIRIDKVFIGSCTNSRIEDLRAAAA 360 Query: 361 VVRGKFRASNVKLAMVVPGSGLVKEQAEREGLDKIFRDAGFEWREPGCSMCLAMNADRLE 420 VVRGK+RASNVKLAMVVPGSGLVKEQAEREGLDKIF+ AGFEWREPGCSMCLAMNADRLE Sbjct: 361 VVRGKYRASNVKLAMVVPGSGLVKEQAEREGLDKIFKAAGFEWREPGCSMCLAMNADRLE 420 Query: 421 PGERCASTSNRNFEGRQGAGGRTHLVSPAMAAAAGIAGHFVDVRSL 466 PGERCASTSNRNFEGRQGAGGRTHLVSPAMAAAAGI GHFVDVR+L Sbjct: 421 PGERCASTSNRNFEGRQGAGGRTHLVSPAMAAAAGIEGHFVDVRAL 466 >ref|YP_001099519.1| isopropylmalate isomerase large subunit [Herminiimonas arsenicoxydans] sp|A4G4F5.1|LEUC_HERAR RecName: Full=3-isopropylmalate dehydratase large subunit; AltName: Full=Alpha-IPM isomerase; Short=IPMI; AltName: Full=Isopropylmalate isomerase emb|CAL61392.1| 3-isopropylmalate dehydratase large subunit (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) [Herminiimonas arsenicoxydans] Length = 466 Score = 867 bits (2240), Expect = 0.0, Method: Compositional matrix adjust. Identities = 410/466 (87%), Positives = 438/466 (93%) Query: 1 MLKTLYDKLWESHVVHAEQDGTAILYIDRHLLHEVTSPQAFEGLKLAGRQPWRNAANLVV 60 M +TLYDKLW+SHVV DGT +LYIDRHLLHEVTSPQAFEGLKLAGR+PWR +ANL+V Sbjct: 1 MAQTLYDKLWQSHVVDTGDDGTTVLYIDRHLLHEVTSPQAFEGLKLAGRRPWRVSANLMV 60 Query: 61 ADHNVPTTNRANGIADPISRLQVETLDANAKEYGLTYFGMNDKRQGIVHVIGPEQGATLP 120 ADHNVPTT+R+ GIADP SRLQVETLD NA EYGLTYF M DKRQGIVHVIGPEQGATLP Sbjct: 61 ADHNVPTTDRSEGIADPTSRLQVETLDHNAHEYGLTYFSMRDKRQGIVHVIGPEQGATLP 120 Query: 121 GMTVVCGDSHTSTHGAFACLAHGIGTSEVEHVLATQTLLAKKSKSMLVQVDGALPNGVTA 180 GMTVVCGDSHTSTHGAF LAHGIGTSEVEHVLATQTLLA+KSK+MLVQVDGALP GVTA Sbjct: 121 GMTVVCGDSHTSTHGAFGALAHGIGTSEVEHVLATQTLLAQKSKAMLVQVDGALPVGVTA 180 Query: 181 KDIVLAVIGKIGTAGGTGYAIEFAGSTMRALTMEGRMTVCNMAIEAGARAGMIAVDDTTI 240 KDIVLA+IGKIGTAGGTGYAIEFAGST+R+L+MEGRMT+CNMAIEAGARAGM+AVD+TTI Sbjct: 181 KDIVLAIIGKIGTAGGTGYAIEFAGSTIRSLSMEGRMTICNMAIEAGARAGMVAVDETTI 240 Query: 241 NYLKGRPFSPAGPHWERAVSYWRTLHSDPGAKFDMVVTLNATEIKPQVTWGTSPEMVIAI 300 NY+KGRP SP GPHW+RAV YWRTLHSD GAKFD+VVTLNA E+KPQV+WGTSPEMV+++ Sbjct: 241 NYVKGRPLSPVGPHWDRAVEYWRTLHSDVGAKFDLVVTLNAAEVKPQVSWGTSPEMVVSV 300 Query: 301 DSRVPDPDKEKDATKRDGMEKALAYMALKPNTPIEDIRIDKVFIGSCTNSRIEDLREAAA 360 D RVPDPDKEKDATKRDGMEKAL YM LKPNTPI DIRIDKVFIGSCTNSRI+DLR AAA Sbjct: 301 DGRVPDPDKEKDATKRDGMEKALVYMGLKPNTPITDIRIDKVFIGSCTNSRIQDLRAAAA 360 Query: 361 VVRGKFRASNVKLAMVVPGSGLVKEQAEREGLDKIFRDAGFEWREPGCSMCLAMNADRLE 420 VVRGK RASNVKLAMVVPGSGLVKEQAEREGLDKIF+DAGFEWREPGCSMCLAMNADRLE Sbjct: 361 VVRGKHRASNVKLAMVVPGSGLVKEQAEREGLDKIFKDAGFEWREPGCSMCLAMNADRLE 420 Query: 421 PGERCASTSNRNFEGRQGAGGRTHLVSPAMAAAAGIAGHFVDVRSL 466 PGERCASTSNRNFEGRQGAGGRTHLVSPAMAAAAGI GHFVDVR+L Sbjct: 421 PGERCASTSNRNFEGRQGAGGRTHLVSPAMAAAAGIEGHFVDVRAL 466 >ref|ZP_08272573.1| 3-isopropylmalate dehydratase large subunit [Oxalobacteraceae bacterium IMCC9480] gb|EGF33962.1| 3-isopropylmalate dehydratase large subunit [Oxalobacteraceae bacterium IMCC9480] Length = 466 Score = 853 bits (2205), Expect = 0.0, Method: Compositional matrix adjust. Identities = 415/466 (89%), Positives = 440/466 (94%) Query: 1 MLKTLYDKLWESHVVHAEQDGTAILYIDRHLLHEVTSPQAFEGLKLAGRQPWRNAANLVV 60 M +TLYDKLW+SHVV DGT ILYIDRHL+HEVTSPQAF+GLKLAGRQPWR +ANL V Sbjct: 1 MAQTLYDKLWDSHVVDTASDGTTILYIDRHLVHEVTSPQAFDGLKLAGRQPWRLSANLAV 60 Query: 61 ADHNVPTTNRANGIADPISRLQVETLDANAKEYGLTYFGMNDKRQGIVHVIGPEQGATLP 120 ADHNVPTT+RA GIADP SRLQVETLDANAK YGLTYF M DKRQGIVHVIGPEQGATLP Sbjct: 61 ADHNVPTTDRAQGIADPTSRLQVETLDANAKTYGLTYFNMADKRQGIVHVIGPEQGATLP 120 Query: 121 GMTVVCGDSHTSTHGAFACLAHGIGTSEVEHVLATQTLLAKKSKSMLVQVDGALPNGVTA 180 GMTVVCGDSHTSTHGAF CLAHGIGTSEVEHVLATQTLL KKS+SMLVQ+DGALP GVTA Sbjct: 121 GMTVVCGDSHTSTHGAFGCLAHGIGTSEVEHVLATQTLLTKKSRSMLVQIDGALPRGVTA 180 Query: 181 KDIVLAVIGKIGTAGGTGYAIEFAGSTMRALTMEGRMTVCNMAIEAGARAGMIAVDDTTI 240 KDIVLAVIG+IGTAGG GYAIEFAGST+R+L+MEGRMTVCNMAIEAGARAGMIAVDDTTI Sbjct: 181 KDIVLAVIGQIGTAGGNGYAIEFAGSTIRSLSMEGRMTVCNMAIEAGARAGMIAVDDTTI 240 Query: 241 NYLKGRPFSPAGPHWERAVSYWRTLHSDPGAKFDMVVTLNATEIKPQVTWGTSPEMVIAI 300 +Y+KGRPFSP GPHWERAVS+WRTLHSD GA+FD+VV L+A++++PQVTWGTSPEMV+AI Sbjct: 241 DYVKGRPFSPVGPHWERAVSWWRTLHSDAGARFDLVVRLDASQVRPQVTWGTSPEMVVAI 300 Query: 301 DSRVPDPDKEKDATKRDGMEKALAYMALKPNTPIEDIRIDKVFIGSCTNSRIEDLREAAA 360 D RVPDPDKEKD TKRD MEKALAYMALKPNT I DIRIDKVFIGSCTNSRIEDLR AAA Sbjct: 301 DDRVPDPDKEKDPTKRDSMEKALAYMALKPNTAIADIRIDKVFIGSCTNSRIEDLRAAAA 360 Query: 361 VVRGKFRASNVKLAMVVPGSGLVKEQAEREGLDKIFRDAGFEWREPGCSMCLAMNADRLE 420 VVRGKFRASNV+LAMVVPGSGLVKEQAEREGLDKIFRDAGFEWREPGCSMCLAMNADRLE Sbjct: 361 VVRGKFRASNVRLAMVVPGSGLVKEQAEREGLDKIFRDAGFEWREPGCSMCLAMNADRLE 420 Query: 421 PGERCASTSNRNFEGRQGAGGRTHLVSPAMAAAAGIAGHFVDVRSL 466 PGERCASTSNRNFEGRQGAGGRTHLVSPAMAAAAGIAGHFVDVR+L Sbjct: 421 PGERCASTSNRNFEGRQGAGGRTHLVSPAMAAAAGIAGHFVDVRTL 466