BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0022.0046.p (276 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_004751838.1| transmembrane drug efflux pump [Collimonas f... 387 e-105 ref|YP_003774945.1| cation/multidrug efflux pump protein [Herbas... 375 e-102 ref|YP_004684454.1| cation/multidrug efflux pump [Cupriavidus ne... 360 1e-97 ref|YP_001795925.1| multidrug efflux system, subunit c [Cupriavi... 358 3e-97 ref|YP_725099.1| cation/multidrug efflux pump [Ralstonia eutroph... 357 9e-97 >ref|YP_004751838.1| transmembrane drug efflux pump [Collimonas fungivorans Ter331] gb|AEK61015.1| Transmembrane drug efflux pump [Collimonas fungivorans Ter331] Length = 1072 Score = 387 bits (993), Expect = e-105, Method: Compositional matrix adjust. Identities = 185/246 (75%), Positives = 215/246 (87%), Gaps = 2/246 (0%) Query: 1 VVDDAIVVLENISRHIEQGMKPVKAALIGAREVGFTVLSMSISLIAVFIPILMMGGIVGR 60 VVDDAIVVLEN+SRHIE+GMKP AAL G +EVGFTVLSMSISLIAVFIPIL+MGGIVGR Sbjct: 399 VVDDAIVVLENVSRHIEEGMKPFAAALKGTKEVGFTVLSMSISLIAVFIPILLMGGIVGR 458 Query: 61 LFREFAVTLSVAILVSLLVSLTTTPMMCAMLLKQESEEERKPGRFFTAVERLFDSMLRGY 120 LFREFAVTLSVAILVSL+VSLTTTPMMCA LLK + ERK GRFF A ER FD+MLRGY Sbjct: 459 LFREFAVTLSVAILVSLVVSLTTTPMMCARLLKHD--PERKQGRFFNATERAFDAMLRGY 516 Query: 121 ERSLAWALRFSPLMIVILLATIALNVYLYVIVPKGFFPQQDTGRLVGGIRGDQSISFQAM 180 ERSLAWALRF+PLM++ILL TI LNVYLY +PKG FPQQDTG ++GGI+GDQSISFQ+M Sbjct: 517 ERSLAWALRFAPLMMLILLGTIVLNVYLYTAIPKGLFPQQDTGLVIGGIQGDQSISFQSM 576 Query: 181 RIKLNEFIEIVRQDPAVANVTAFTGGGRRNGGSMFIALKPLSERKISADKVIARLRMKLG 240 R+KL++F++IVR+DP V +V AFTGGG+ N G MFI L+PL++RK++AD+VIARLR KL Sbjct: 577 RVKLDQFVDIVRKDPDVKSVIAFTGGGQSNRGQMFITLQPLTQRKLTADQVIARLRGKLS 636 Query: 241 HVAXCR 246 H+A Sbjct: 637 HIAGAN 642 >ref|YP_003774945.1| cation/multidrug efflux pump protein [Herbaspirillum seropedicae SmR1] gb|ADJ63037.1| cation/multidrug efflux pump protein [Herbaspirillum seropedicae SmR1] Length = 1078 Score = 375 bits (964), Expect = e-102, Method: Compositional matrix adjust. Identities = 189/254 (74%), Positives = 213/254 (83%), Gaps = 8/254 (3%) Query: 1 VVDDAIVVLENISRHIEQGMKPVKAALIGAREVGFTVLSMSISLIAVFIPILMMGGIVGR 60 VVDDAIVVLENISRHIE GMKP KAAL+GAREVGFTVLSMSISLIAVFIPILMM GIVGR Sbjct: 399 VVDDAIVVLENISRHIESGMKPYKAALLGAREVGFTVLSMSISLIAVFIPILMMEGIVGR 458 Query: 61 LFREFAVTLSVAILVSLLVSLTTTPMMCAMLLKQE--SEEERKPGRF------FTAVERL 112 LFREFA+TLSVAILVSL+VSLTTTPMMCA LL+ + ++E R+ R + Sbjct: 459 LFREFAITLSVAILVSLVVSLTTTPMMCAQLLRHDPAADEARRQRRHPWLQKIADQSAAI 518 Query: 113 FDSMLRGYERSLAWALRFSPLMIVILLATIALNVYLYVIVPKGFFPQQDTGRLVGGIRGD 172 F+ ML Y+R+LAWALR +PLM++ILLATIALNVYLY +PKGFFPQQDTGRLVGGIRGD Sbjct: 519 FEDMLLAYQRTLAWALRAAPLMMLILLATIALNVYLYKAIPKGFFPQQDTGRLVGGIRGD 578 Query: 173 QSISFQAMRIKLNEFIEIVRQDPAVANVTAFTGGGRRNGGSMFIALKPLSERKISADKVI 232 Q+ISFQAMR KLNEFI+IVR DPAV++V AFTGG RRNGG M++ LKPLSERK SADKV+ Sbjct: 579 QAISFQAMRTKLNEFIDIVRADPAVSDVVAFTGGQRRNGGFMYVTLKPLSERKDSADKVV 638 Query: 233 ARLRMKLGHVAXCR 246 ARLR+K VA R Sbjct: 639 ARLRIKTAKVAGAR 652 >ref|YP_004684454.1| cation/multidrug efflux pump [Cupriavidus necator N-1] gb|AEI75973.1| cation/multidrug efflux pump [Cupriavidus necator N-1] Length = 1099 Score = 360 bits (925), Expect = 1e-97, Method: Compositional matrix adjust. Identities = 182/240 (75%), Positives = 203/240 (84%), Gaps = 2/240 (0%) Query: 1 VVDDAIVVLENISRHIEQGMKPVKAALIGAREVGFTVLSMSISLIAVFIPILMMGGIVGR 60 VVDDAIVVLENISRHIE+GMKP+ AAL GAREVGFTVLSMS+SLIAVFIP+LMMGGIVGR Sbjct: 463 VVDDAIVVLENISRHIEEGMKPLAAALRGAREVGFTVLSMSLSLIAVFIPLLMMGGIVGR 522 Query: 61 LFREFAVTLSVAILVSLLVSLTTTPMMCAMLLKQESEEERKPGRFFTAVERLFDSMLRGY 120 LF+EFA+TLSVAILVSL+VSLTTTPMMCA LL+ E K RFF A ER+F + GY Sbjct: 523 LFQEFAITLSVAILVSLVVSLTTTPMMCARLLR--PPEPEKQSRFFRATERMFQWLHDGY 580 Query: 121 ERSLAWALRFSPLMIVILLATIALNVYLYVIVPKGFFPQQDTGRLVGGIRGDQSISFQAM 180 RSL+ ALRFSPL+ ++L+ATIALNVYLYVIVPKGFFPQQDTGRL+G IR DQ+ SFQAM Sbjct: 581 ARSLSTALRFSPLVWLVLIATIALNVYLYVIVPKGFFPQQDTGRLIGFIRADQATSFQAM 640 Query: 181 RIKLNEFIEIVRQDPAVANVTAFTGGGRRNGGSMFIALKPLSERKISADKVIARLRMKLG 240 R KL+ FI IVR DPAV NVT FTGG +RN G MF+ LKPLSERK SAD +IARLR KL Sbjct: 641 RGKLDNFITIVRSDPAVENVTGFTGGSQRNTGQMFVTLKPLSERKESADAIIARLRGKLA 700 >ref|YP_001795925.1| multidrug efflux system, subunit c [Cupriavidus taiwanensis LMG 19424] emb|CAP63205.1| multidrug efflux system, subunit C [Cupriavidus taiwanensis LMG 19424] Length = 1099 Score = 358 bits (920), Expect = 3e-97, Method: Compositional matrix adjust. Identities = 180/241 (74%), Positives = 204/241 (84%), Gaps = 2/241 (0%) Query: 1 VVDDAIVVLENISRHIEQGMKPVKAALIGAREVGFTVLSMSISLIAVFIPILMMGGIVGR 60 VVDDAIVVLENISRHIE+GMKP+ AAL GAREVGFTVLSMS+SLIAVFIP+LMMGGIVGR Sbjct: 463 VVDDAIVVLENISRHIEEGMKPLAAALRGAREVGFTVLSMSLSLIAVFIPLLMMGGIVGR 522 Query: 61 LFREFAVTLSVAILVSLLVSLTTTPMMCAMLLKQESEEERKPGRFFTAVERLFDSMLRGY 120 LF+EFA+TLSVAILVSL+VSLTTTPMMCA +L+ E K GRFF A ER+F + GY Sbjct: 523 LFQEFAITLSVAILVSLVVSLTTTPMMCARMLR--PVEPEKQGRFFRATERMFQWLHDGY 580 Query: 121 ERSLAWALRFSPLMIVILLATIALNVYLYVIVPKGFFPQQDTGRLVGGIRGDQSISFQAM 180 RSL+ ALR SPL+ ++L+ATIALNVYLYVIVPKGFFPQQDTGRL+G IR DQ+ SFQAM Sbjct: 581 ARSLSTALRLSPLVWLVLIATIALNVYLYVIVPKGFFPQQDTGRLIGFIRADQATSFQAM 640 Query: 181 RIKLNEFIEIVRQDPAVANVTAFTGGGRRNGGSMFIALKPLSERKISADKVIARLRMKLG 240 R KL+ FI+IV+ DPAV NVT FTGG +RN G MF+ LKPLSERK SAD +IARLR KL Sbjct: 641 RGKLDNFIKIVQSDPAVVNVTGFTGGSQRNTGQMFVTLKPLSERKESADAIIARLRGKLA 700 Query: 241 H 241 Sbjct: 701 K 701 >ref|YP_725099.1| cation/multidrug efflux pump [Ralstonia eutropha H16] emb|CAJ91731.1| Cation/multidrug efflux pump [Ralstonia eutropha H16] Length = 1099 Score = 357 bits (917), Expect = 9e-97, Method: Compositional matrix adjust. Identities = 179/239 (74%), Positives = 203/239 (84%), Gaps = 2/239 (0%) Query: 1 VVDDAIVVLENISRHIEQGMKPVKAALIGAREVGFTVLSMSISLIAVFIPILMMGGIVGR 60 VVDDAIVVLENISRHIE+GMKP+ AAL GAREVGFTVLSMS+SLIAVFIP+LMMGGIVGR Sbjct: 463 VVDDAIVVLENISRHIEEGMKPLAAALRGAREVGFTVLSMSLSLIAVFIPLLMMGGIVGR 522 Query: 61 LFREFAVTLSVAILVSLLVSLTTTPMMCAMLLKQESEEERKPGRFFTAVERLFDSMLRGY 120 LF+EFA+TLSVAILVSL+VSLTTTPMMCA +L+ E K GRFF A ER+F + GY Sbjct: 523 LFQEFAITLSVAILVSLVVSLTTTPMMCARMLR--PPEPEKQGRFFRATERMFQWLHDGY 580 Query: 121 ERSLAWALRFSPLMIVILLATIALNVYLYVIVPKGFFPQQDTGRLVGGIRGDQSISFQAM 180 RSL+ ALR SPL+ ++L+ATIALNVYLYVIVPKGFFPQQDTGRL+G IR DQ+ SFQAM Sbjct: 581 ARSLSTALRLSPLVWLVLIATIALNVYLYVIVPKGFFPQQDTGRLIGFIRADQATSFQAM 640 Query: 181 RIKLNEFIEIVRQDPAVANVTAFTGGGRRNGGSMFIALKPLSERKISADKVIARLRMKL 239 R KL+ FI+IV+ DPAV NVT FTGG +RN G MF+ LKPLSER SAD +IARLR KL Sbjct: 641 RGKLDNFIKIVQSDPAVVNVTGFTGGSQRNTGQMFVTLKPLSERNESADAIIARLRGKL 699