BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0017.0125.p (234 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gb|EFV87718.1| thiopurine S-methyltransferase [Achromobacter xyl... 361 4e-98 gb|EGP47985.1| thiopurine S-methyltransferase [Achromobacter xyl... 358 4e-97 ref|NP_884416.1| thiopurine S-methyltransferase [Bordetella para... 352 2e-95 ref|NP_879683.1| thiopurine S-methyltransferase [Bordetella pert... 351 6e-95 ref|ZP_06689288.1| thiopurine S-methyltransferase [Achromobacter... 350 7e-95 >gb|EFV87718.1| thiopurine S-methyltransferase [Achromobacter xylosoxidans C54] Length = 219 Score = 361 bits (927), Expect = 4e-98, Method: Compositional matrix adjust. Identities = 170/215 (79%), Positives = 191/215 (88%) Query: 16 MEAEFWLERWRDGRTHFHQTRVTPLLQKYWPALALPQGSQVLVPLAGKSLDMVWLASQGH 75 M+AEFWLERWRDGRTHFHQTRVTPLLQKYWP L++P G +VLVPL GKSLDMVWLA+QG+ Sbjct: 1 MDAEFWLERWRDGRTHFHQTRVTPLLQKYWPTLSVPAGGKVLVPLCGKSLDMVWLAAQGY 60 Query: 76 RVLGVELSQLAVEQFFDENRLQPQIRESAYGRHYTAGDVEIICGDIFKLDAALLSACVGV 135 +VLGVELSQLAVEQFF EN L+P I ESAYGRHY AG++EIICGDIFKLDA LLS CVG Sbjct: 61 QVLGVELSQLAVEQFFTENELKPVIHESAYGRHYVAGNIEIICGDIFKLDAPLLSHCVGA 120 Query: 136 YDRAALVALPADMRARYARHVYGQLSAHYRGILITLDYPQEQMDGPPFSVGDAEVQAIFA 195 YDRAALVALPADMR Y RHVYGQL+ YRG+LITLDYPQE+MDGPPF+V DAE++ +F Sbjct: 121 YDRAALVALPADMRGDYVRHVYGQLAPGYRGLLITLDYPQEEMDGPPFAVVDAEMRNLFT 180 Query: 196 AHSEALVIDRRDILDKEPKFSERGVSRLDTVVYQL 230 S A++IDRRDIL KEPKF+ERGVSRLDTVVY+L Sbjct: 181 GVSPAVIIDRRDILAKEPKFAERGVSRLDTVVYRL 215 >gb|EGP47985.1| thiopurine S-methyltransferase [Achromobacter xylosoxidans AXX-A] Length = 219 Score = 358 bits (919), Expect = 4e-97, Method: Compositional matrix adjust. Identities = 168/215 (78%), Positives = 191/215 (88%) Query: 16 MEAEFWLERWRDGRTHFHQTRVTPLLQKYWPALALPQGSQVLVPLAGKSLDMVWLASQGH 75 M+AEFWLERWRDGRTHFHQ RVTPLLQKYWP L++P G +VLVPL GKSLDMVWLA+QG Sbjct: 1 MDAEFWLERWRDGRTHFHQARVTPLLQKYWPTLSVPAGGKVLVPLCGKSLDMVWLAAQGF 60 Query: 76 RVLGVELSQLAVEQFFDENRLQPQIRESAYGRHYTAGDVEIICGDIFKLDAALLSACVGV 135 +VLGVELSQLAVEQFF EN L+P I++SAYGRHY AG++EIICGDIFKLDA LLS CVG Sbjct: 61 QVLGVELSQLAVEQFFVENELKPVIQDSAYGRHYVAGNIEIICGDIFKLDAPLLSHCVGA 120 Query: 136 YDRAALVALPADMRARYARHVYGQLSAHYRGILITLDYPQEQMDGPPFSVGDAEVQAIFA 195 YDRAALVALP +MR Y RHVYGQLS YRG+LITLDYPQE+MDGPPF+V DAE++A+F+ Sbjct: 121 YDRAALVALPVEMRGEYVRHVYGQLSPGYRGLLITLDYPQEEMDGPPFAVVDAEMRALFS 180 Query: 196 AHSEALVIDRRDILDKEPKFSERGVSRLDTVVYQL 230 S A++IDRRDIL KEPKF+ERGVSRLDTVVY+L Sbjct: 181 GVSPAVIIDRRDILTKEPKFAERGVSRLDTVVYRL 215 >ref|NP_884416.1| thiopurine S-methyltransferase [Bordetella parapertussis 12822] ref|NP_888102.1| thiopurine S-methyltransferase [Bordetella bronchiseptica RB50] sp|Q7W8H4.1|TPMT_BORPA RecName: Full=Thiopurine S-methyltransferase; AltName: Full=Thiopurine methyltransferase sp|Q7WM36.1|TPMT_BORBR RecName: Full=Thiopurine S-methyltransferase; AltName: Full=Thiopurine methyltransferase emb|CAE32054.1| thiopurine S-methyltransferase [Bordetella bronchiseptica RB50] emb|CAE37460.1| thiopurine S-methyltransferase [Bordetella parapertussis] Length = 219 Score = 352 bits (903), Expect = 2e-95, Method: Compositional matrix adjust. Identities = 167/219 (76%), Positives = 194/219 (88%) Query: 16 MEAEFWLERWRDGRTHFHQTRVTPLLQKYWPALALPQGSQVLVPLAGKSLDMVWLASQGH 75 M+A+FWL+RWR+GRTHFHQTRVTPLLQKYWPAL +P G QVLVPLAGKSLDMVWLA QG Sbjct: 1 MDADFWLDRWREGRTHFHQTRVTPLLQKYWPALDVPAGGQVLVPLAGKSLDMVWLAGQGL 60 Query: 76 RVLGVELSQLAVEQFFDENRLQPQIRESAYGRHYTAGDVEIICGDIFKLDAALLSACVGV 135 RVLGVELSQLAVEQFFDEN L+P+I +SA GRHY AG++E+ICGD+F L+ A L+AC GV Sbjct: 61 RVLGVELSQLAVEQFFDENGLRPEIHQSAQGRHYVAGNLELICGDVFALEDATLAACAGV 120 Query: 136 YDRAALVALPADMRARYARHVYGQLSAHYRGILITLDYPQEQMDGPPFSVGDAEVQAIFA 195 YDRAALVALP MR RYAR VYG+L RGILITLDYPQ+QM+GPPFSV DAEVQA++A Sbjct: 121 YDRAALVALPEPMRKRYAREVYGRLGRGCRGILITLDYPQDQMEGPPFSVDDAEVQALYA 180 Query: 196 AHSEALVIDRRDILDKEPKFSERGVSRLDTVVYQLQRKG 234 H+EA +IDRRDILDKEPKF++RGV+RLDT+VY+L+R G Sbjct: 181 GHTEARLIDRRDILDKEPKFNQRGVARLDTLVYRLERLG 219 >ref|NP_879683.1| thiopurine S-methyltransferase [Bordetella pertussis Tohama I] sp|Q7VZM5.1|TPMT_BORPE RecName: Full=Thiopurine S-methyltransferase; AltName: Full=Thiopurine methyltransferase emb|CAE41176.1| thiopurine S-methyltransferase [Bordetella pertussis Tohama I] gb|AEE66302.1| thiopurine S-methyltransferase [Bordetella pertussis CS] Length = 219 Score = 351 bits (900), Expect = 6e-95, Method: Compositional matrix adjust. Identities = 166/219 (75%), Positives = 193/219 (88%) Query: 16 MEAEFWLERWRDGRTHFHQTRVTPLLQKYWPALALPQGSQVLVPLAGKSLDMVWLASQGH 75 M+A+FWL+RWR+GRTHFHQTRVTPLLQKYWP L +P G QVLVPLAGKSLDMVWLA QG Sbjct: 1 MDADFWLDRWREGRTHFHQTRVTPLLQKYWPTLDVPAGGQVLVPLAGKSLDMVWLAGQGL 60 Query: 76 RVLGVELSQLAVEQFFDENRLQPQIRESAYGRHYTAGDVEIICGDIFKLDAALLSACVGV 135 RVLGVELSQLAVEQFFDEN L+P+I +SA GRHY AG++E+ICGD+F L+ A L+AC GV Sbjct: 61 RVLGVELSQLAVEQFFDENDLRPEIHQSAQGRHYVAGNLELICGDVFALEDATLAACAGV 120 Query: 136 YDRAALVALPADMRARYARHVYGQLSAHYRGILITLDYPQEQMDGPPFSVGDAEVQAIFA 195 YDRAALVALP MR RYAR VYG+L RGILITLDYPQ+QM+GPPFSV DAEVQA++A Sbjct: 121 YDRAALVALPEPMRKRYAREVYGRLGRGCRGILITLDYPQDQMEGPPFSVDDAEVQALYA 180 Query: 196 AHSEALVIDRRDILDKEPKFSERGVSRLDTVVYQLQRKG 234 H+EA +IDRRDILDKEPKF++RGV+RLDT+VY+L+R G Sbjct: 181 GHTEARLIDRRDILDKEPKFNQRGVARLDTLVYRLERLG 219 >ref|ZP_06689288.1| thiopurine S-methyltransferase [Achromobacter piechaudii ATCC 43553] gb|EFF73807.1| thiopurine S-methyltransferase [Achromobacter piechaudii ATCC 43553] Length = 220 Score = 350 bits (899), Expect = 7e-95, Method: Compositional matrix adjust. Identities = 163/215 (75%), Positives = 187/215 (86%) Query: 16 MEAEFWLERWRDGRTHFHQTRVTPLLQKYWPALALPQGSQVLVPLAGKSLDMVWLASQGH 75 M+AEFWLERWR+GRTHFHQTR+TPLLQKYWP LA+P+G +VLVPL GKSLDMVWLA+QGH Sbjct: 1 MDAEFWLERWREGRTHFHQTRITPLLQKYWPTLAVPKGGRVLVPLCGKSLDMVWLAAQGH 60 Query: 76 RVLGVELSQLAVEQFFDENRLQPQIRESAYGRHYTAGDVEIICGDIFKLDAALLSACVGV 135 VLG+ELSQLAVEQFF EN L+P ES YG+HY AG++EIICGDIFKLD+ +LS CVG Sbjct: 61 TVLGIELSQLAVEQFFSENELRPVTHESLYGKHYVAGNIEIICGDIFKLDSQVLSHCVGA 120 Query: 136 YDRAALVALPADMRARYARHVYGQLSAHYRGILITLDYPQEQMDGPPFSVGDAEVQAIFA 195 YDRAALVALP +MRA Y RHVYGQLS RG+LITLDYPQE+M GPPF+V D+EVQAIF+ Sbjct: 121 YDRAALVALPEEMRAAYVRHVYGQLSPASRGLLITLDYPQEEMAGPPFAVLDSEVQAIFS 180 Query: 196 AHSEALVIDRRDILDKEPKFSERGVSRLDTVVYQL 230 + A++IDRRDILDKEPKF GVSRLDTVVY+L Sbjct: 181 GVAPAVIIDRRDILDKEPKFQSAGVSRLDTVVYRL 215