BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0015.0185.p (487 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_004682810.1| aldehyde dehydrogenase DhaS [Cupriavidus nec... 729 0.0 ref|YP_004687998.1| aldehyde dehydrogenase DhaS [Cupriavidus nec... 728 0.0 ref|YP_725996.1| NAD-dependent aldehyde dehydrogenase [Ralstonia... 603 e-170 ref|YP_554298.1| aldehyde dehydrogenase [Burkholderia xenovorans... 594 e-167 ref|YP_002825159.1| putative aldehyde dehydrogenase [Sinorhizobi... 588 e-166 >ref|YP_004682810.1| aldehyde dehydrogenase DhaS [Cupriavidus necator N-1] gb|AEI82962.1| aldehyde dehydrogenase DhaS [Cupriavidus necator N-1] Length = 492 Score = 729 bits (1882), Expect = 0.0, Method: Compositional matrix adjust. Identities = 341/487 (70%), Positives = 408/487 (83%) Query: 1 MLIGGVWQDSASGEWIDSIEPFSGDVIAQVPRGNEADAAQAVDAAYKAYRSPAWSELTAT 60 M I W DS SG+W +SIEP+SG A+VP+GN D +AV AA A+ PAW +LTAT Sbjct: 6 MFINNEWVDSTSGQWFESIEPYSGKAWAEVPKGNAQDVEKAVQAAKAAFDDPAWRDLTAT 65 Query: 61 QRGALLRKLGDLIERDAVRLADIERSCNGKNITEVSGQVRNVAQWFYYYAGLADKIHGSV 120 QRGALLR+L +L+ + RLAD E+ NGK I EVSGQV+NVAQWF+YYAGLADK+ G+V Sbjct: 66 QRGALLRRLAELVSTNVTRLADTEQRDNGKLIAEVSGQVQNVAQWFHYYAGLADKVQGAV 125 Query: 121 VPINKPGVFNYVRYEPLGVVVAITPWNSPLALTAWKMAPALACGNTIVVKPSEFTSPPLL 180 VPINKPGVFNY+++EPLGVV AITPWNSPLALT WKMAPALA GNT+V+KPSE+TS LL Sbjct: 126 VPINKPGVFNYIKHEPLGVVAAITPWNSPLALTVWKMAPALAAGNTMVIKPSEYTSASLL 185 Query: 181 ELAALASEAGFPPGVINVVSGYGNEIGAALINHPRVAKIAFTGGDIGGQKVAEAAAKNFK 240 ELAAL EAGFPPGV+NV++G+G ++G L+ H +AKIAFTGGDI GQ++ E AA +FK Sbjct: 186 ELAALTKEAGFPPGVVNVITGFGADVGEPLVRHQDIAKIAFTGGDIAGQRINEIAASDFK 245 Query: 241 KITLELGGKSANIVFADADFEQAINGAIAGVFGAAGQTCMAGSRLLVERSIHDKFVARLI 300 K+TLELGGKSANIVF DAD +QA+ GA+AG+FGAAGQTCMAGSRLLV+R++HD+FV LI Sbjct: 246 KVTLELGGKSANIVFDDADLDQAVKGAVAGIFGAAGQTCMAGSRLLVQRNVHDQFVEMLI 305 Query: 301 EVAGAARIGNPADSETQVGPIATRSQYEKILGYIEIAKQDGATCVLGGNALSGAQYGQGQ 360 +VA A IG+P+ ETQVGPIAT +Q+ KIL YIEIAK GA CVLGG+AL+G YGQGQ Sbjct: 306 KVASDAVIGDPSKHETQVGPIATEAQFRKILSYIEIAKSGGAHCVLGGHALTGDAYGQGQ 365 Query: 361 FVAPTIFTNVRNDMRIAREEVFGPILSVIPFDSVEEALEIANDTDFGLAAAVWTTDLHKA 420 F+APTIFT V NDMRIA+EEVFGP+L+VIPFD+ ++AL IANDT FGLAA VWT+DLH+A Sbjct: 366 FIAPTIFTGVTNDMRIAQEEVFGPVLAVIPFDTEDDALRIANDTMFGLAAGVWTSDLHRA 425 Query: 421 IYCSDRIEAGTVWVNNYRATSFTTPFGGYKRSGVGREGGLEGAQEYMQAKSVWITTQPNK 480 Y SDR++AGTVWVNNYRATSFTTPFGGYKRSG+GREGG++ +EY+Q KSVWITT+P K Sbjct: 426 FYMSDRLKAGTVWVNNYRATSFTTPFGGYKRSGIGREGGVDAIKEYLQTKSVWITTKPAK 485 Query: 481 QNAFVLG 487 NAFVLG Sbjct: 486 ANAFVLG 492 >ref|YP_004687998.1| aldehyde dehydrogenase DhaS [Cupriavidus necator N-1] gb|AEI81960.1| aldehyde dehydrogenase DhaS [Cupriavidus necator N-1] Length = 487 Score = 728 bits (1878), Expect = 0.0, Method: Compositional matrix adjust. Identities = 340/487 (69%), Positives = 409/487 (83%) Query: 1 MLIGGVWQDSASGEWIDSIEPFSGDVIAQVPRGNEADAAQAVDAAYKAYRSPAWSELTAT 60 M I W DS SG+W +SIEP+SG A+VP+GN D +AV AA A+ PAW +LTAT Sbjct: 1 MFINNEWVDSTSGQWFESIEPYSGKAWAEVPKGNAQDVEKAVQAAKAAFDDPAWRDLTAT 60 Query: 61 QRGALLRKLGDLIERDAVRLADIERSCNGKNITEVSGQVRNVAQWFYYYAGLADKIHGSV 120 QRGALLR+L +L+ + RLA+ E+ NGK I EVSGQV+NVAQWF+YYAGLADK+ G+V Sbjct: 61 QRGALLRRLAELVSTNVARLAETEQRDNGKLIAEVSGQVQNVAQWFHYYAGLADKVQGAV 120 Query: 121 VPINKPGVFNYVRYEPLGVVVAITPWNSPLALTAWKMAPALACGNTIVVKPSEFTSPPLL 180 VPINKPGVFNY+++EPLGVV AITPWNSPLALT WKMAPALA GNT+V+KPSE+TS LL Sbjct: 121 VPINKPGVFNYIKHEPLGVVAAITPWNSPLALTVWKMAPALAAGNTMVIKPSEYTSASLL 180 Query: 181 ELAALASEAGFPPGVINVVSGYGNEIGAALINHPRVAKIAFTGGDIGGQKVAEAAAKNFK 240 ELAAL EAGFPPGV+NV++G+G ++G L+ H +AKIAFTGGDI GQ++ E AA +FK Sbjct: 181 ELAALTKEAGFPPGVVNVITGFGADVGEPLVRHKDIAKIAFTGGDIAGQRINEIAASDFK 240 Query: 241 KITLELGGKSANIVFADADFEQAINGAIAGVFGAAGQTCMAGSRLLVERSIHDKFVARLI 300 K+TLELGGKSANIVF DAD +QA+ GA+AG+FGAAGQTCMAGSRLLV+R++HD+FV LI Sbjct: 241 KVTLELGGKSANIVFDDADLDQAVKGAVAGIFGAAGQTCMAGSRLLVQRNVHDQFVEMLI 300 Query: 301 EVAGAARIGNPADSETQVGPIATRSQYEKILGYIEIAKQDGATCVLGGNALSGAQYGQGQ 360 +VA A IG+P+ ETQVGPIAT +Q+ KIL YIEIAK+ GA CVLGG+AL+G YGQGQ Sbjct: 301 KVASEAVIGDPSKQETQVGPIATEAQFRKILSYIEIAKRGGARCVLGGHALTGDAYGQGQ 360 Query: 361 FVAPTIFTNVRNDMRIAREEVFGPILSVIPFDSVEEALEIANDTDFGLAAAVWTTDLHKA 420 F+APTIFT V NDMRIA+EEVFGP+L+VIPFD+ ++AL IANDT FGLAA VWT+DLH+A Sbjct: 361 FIAPTIFTGVTNDMRIAQEEVFGPVLAVIPFDTEDDALRIANDTMFGLAAGVWTSDLHRA 420 Query: 421 IYCSDRIEAGTVWVNNYRATSFTTPFGGYKRSGVGREGGLEGAQEYMQAKSVWITTQPNK 480 Y SDR++AGTVWVNNYRATSFTTPFGGYKRSG+GREGG++ +EY+Q KSVWITT+P K Sbjct: 421 FYMSDRLKAGTVWVNNYRATSFTTPFGGYKRSGIGREGGVDAIKEYLQTKSVWITTKPAK 480 Query: 481 QNAFVLG 487 NAFVLG Sbjct: 481 ANAFVLG 487 >ref|YP_725996.1| NAD-dependent aldehyde dehydrogenase [Ralstonia eutropha H16] emb|CAJ92628.1| NAD-dependent aldehyde dehydrogenase [Ralstonia eutropha H16] Length = 493 Score = 603 bits (1554), Expect = e-170, Method: Compositional matrix adjust. Identities = 290/485 (59%), Positives = 363/485 (74%), Gaps = 1/485 (0%) Query: 1 MLIGGVWQDSASGEWIDSIEPFSGDVIAQVPRGNEADAAQAVDAAYKAYRSPAWSELTAT 60 + I W D + G+W +S++PF+G+ A++PRG D +A AA A + P WS+++AT Sbjct: 7 LFINNEWVDPSRGQWFESLDPFTGEAWAEIPRGTREDVDRAAQAAAAAMKGP-WSKMSAT 65 Query: 61 QRGALLRKLGDLIERDAVRLADIERSCNGKNITEVSGQVRNVAQWFYYYAGLADKIHGSV 120 RG LL KL LIE + L ++E NGK +EV GQV VA++FYYYAG+ADKI G+V Sbjct: 66 NRGMLLYKLAGLIEENIDLLTEVEARDNGKLRSEVRGQVGYVAKYFYYYAGMADKIQGAV 125 Query: 121 VPINKPGVFNYVRYEPLGVVVAITPWNSPLALTAWKMAPALACGNTIVVKPSEFTSPPLL 180 VP++KP VFNY R EP+GVV ITPWNS L LTAWK+APAL GN IV KPSE TS LL Sbjct: 126 VPMDKPKVFNYTRLEPVGVVGTITPWNSSLLLTAWKVAPALCAGNAIVAKPSEHTSASLL 185 Query: 181 ELAALASEAGFPPGVINVVSGYGNEIGAALINHPRVAKIAFTGGDIGGQKVAEAAAKNFK 240 ELA L +AGFPPGV NVV+G+G ++G L+ HP V IAFTGGD GG++V AAA +FK Sbjct: 186 ELARLFVKAGFPPGVFNVVTGFGRDVGEPLVEHPLVPMIAFTGGDEGGRRVNLAAAAHFK 245 Query: 241 KITLELGGKSANIVFADADFEQAINGAIAGVFGAAGQTCMAGSRLLVERSIHDKFVARLI 300 K+TLELGGKS NIVF DAD A NG I G+F A GQTCMAGSRLL++ SIHD+FV RL+ Sbjct: 246 KVTLELGGKSPNIVFDDADLTNAANGVITGIFSAGGQTCMAGSRLLLQESIHDEFVDRLV 305 Query: 301 EVAGAARIGNPADSETQVGPIATRSQYEKILGYIEIAKQDGATCVLGGNALSGAQYGQGQ 360 + A++G+PA S+ Q+GP+ATR Q+EK++ YI IA++DGATC GG SGA YG GQ Sbjct: 306 AITSKAKLGDPARSDVQMGPVATRPQFEKVVDYIRIAREDGATCAFGGKTRSGADYGAGQ 365 Query: 361 FVAPTIFTNVRNDMRIAREEVFGPILSVIPFDSVEEALEIANDTDFGLAAAVWTTDLHKA 420 FV PTIFTNV NDMRIA+EEVFGP+LSV+ F ++AL IAND FGLAA VWT LH+A Sbjct: 366 FVEPTIFTNVTNDMRIAQEEVFGPVLSVLKFKDEDDALRIANDIRFGLAAGVWTKSLHRA 425 Query: 421 IYCSDRIEAGTVWVNNYRATSFTTPFGGYKRSGVGREGGLEGAQEYMQAKSVWITTQPNK 480 +Y S+R++AGTVW+NNYR+TSFTTPFGGYK SG+GREGG E +E+M+ KSVW++T Sbjct: 426 MYMSERLQAGTVWINNYRSTSFTTPFGGYKDSGLGREGGTEAVKEFMETKSVWVSTDLEM 485 Query: 481 QNAFV 485 + FV Sbjct: 486 PDPFV 490 >ref|YP_554298.1| aldehyde dehydrogenase [Burkholderia xenovorans LB400] gb|ABE34948.1| aldehyde dehydrogenase (acceptor) [Burkholderia xenovorans LB400] Length = 491 Score = 594 bits (1531), Expect = e-167, Method: Compositional matrix adjust. Identities = 284/477 (59%), Positives = 373/477 (78%), Gaps = 1/477 (0%) Query: 1 MLIGGVWQDSASGEWIDSIEPFSGDVIAQVPRGNEADAAQAVDAAYKAYRSPAWSELTAT 60 + I W D SG W ++ +PF+G+ A++PR + DA +AV AA KA P WS L+A+ Sbjct: 6 LFIDNEWVDPHSGAWFETDDPFTGEPWAEIPRADPTDADRAVRAAEKALEGP-WSTLSAS 64 Query: 61 QRGALLRKLGDLIERDAVRLADIERSCNGKNITEVSGQVRNVAQWFYYYAGLADKIHGSV 120 +RG L+ KLG LIERDA LA IE NGK +V GQ++ +A+++YY+ GLADKI G+V Sbjct: 65 ERGMLMYKLGALIERDAEHLATIESRDNGKLFRDVLGQMKYMAKYYYYFGGLADKIQGAV 124 Query: 121 VPINKPGVFNYVRYEPLGVVVAITPWNSPLALTAWKMAPALACGNTIVVKPSEFTSPPLL 180 VPI+KPG+FN++RYEP+GVV++ITPWNS L LT WKMAPAL GNTIV KPSEFTS L Sbjct: 125 VPIDKPGIFNFIRYEPMGVVLSITPWNSSLPLTTWKMAPALCAGNTIVCKPSEFTSASLF 184 Query: 181 ELAALASEAGFPPGVINVVSGYGNEIGAALINHPRVAKIAFTGGDIGGQKVAEAAAKNFK 240 ELA L EAGFP GV NVV+G+G EIGA+L++HP VA+IAFTGGD G+K+ AAA++ K Sbjct: 185 ELAKLFVEAGFPRGVFNVVTGFGPEIGASLVSHPGVARIAFTGGDEAGRKIYAAAAQHLK 244 Query: 241 KITLELGGKSANIVFADADFEQAINGAIAGVFGAAGQTCMAGSRLLVERSIHDKFVARLI 300 +++LELGGKS NIVF DAD +QA+NG I+G+F A GQTC+AGSR+L++ SIHD FV R+ Sbjct: 245 RVSLELGGKSPNIVFDDADLDQAVNGVISGIFSATGQTCVAGSRVLLQESIHDAFVERVA 304 Query: 301 EVAGAARIGNPADSETQVGPIATRSQYEKILGYIEIAKQDGATCVLGGNALSGAQYGQGQ 360 ++ AA++GNP D +++GPI T+ Q+EKILGYI+IA ++GA CV GG ALSG YG G+ Sbjct: 305 KLTRAAKVGNPLDPASEIGPITTKPQFEKILGYIDIATREGARCVAGGRALSGPGYGAGR 364 Query: 361 FVAPTIFTNVRNDMRIAREEVFGPILSVIPFDSVEEALEIANDTDFGLAAAVWTTDLHKA 420 FV PT+F +V NDMRIA+EEVFGP+LS+I F E+A+ I ND FGLAA VWT LH+A Sbjct: 365 FVEPTVFVDVTNDMRIAQEEVFGPVLSIIRFKDEEDAIRIGNDIKFGLAAGVWTNSLHRA 424 Query: 421 IYCSDRIEAGTVWVNNYRATSFTTPFGGYKRSGVGREGGLEGAQEYMQAKSVWITTQ 477 + S R++AGTVW+NNYR++SFTTPFGG+K+SG+GREGG+E +E+M+AKSVW+++ Sbjct: 425 MLMSQRLKAGTVWINNYRSSSFTTPFGGFKQSGIGREGGIESVKEFMEAKSVWMSSD 481 >ref|YP_002825159.1| putative aldehyde dehydrogenase [Sinorhizobium fredii NGR234] gb|ACP24406.1| putative aldehyde dehydrogenase [Sinorhizobium fredii NGR234] Length = 492 Score = 588 bits (1516), Expect = e-166, Method: Compositional matrix adjust. Identities = 279/486 (57%), Positives = 360/486 (74%) Query: 1 MLIGGVWQDSASGEWIDSIEPFSGDVIAQVPRGNEADAAQAVDAAYKAYRSPAWSELTAT 60 MLI G W D+A GE ++ P++GDV A +P+G + DA +AV+AA+KA+ S W +LTA+ Sbjct: 6 MLIDGQWADAALGETFETRNPYTGDVWAAIPKGTKEDAERAVEAAHKAFTSGTWPKLTAS 65 Query: 61 QRGALLRKLGDLIERDAVRLADIERSCNGKNITEVSGQVRNVAQWFYYYAGLADKIHGSV 120 RG LLR+LGDLI +A RLA IE + NGK I E+ Q++ + QW++Y+ GLADKI G+V Sbjct: 66 DRGHLLRRLGDLIAENAERLARIEVTDNGKLINEMLFQLKYIPQWYHYFGGLADKIEGAV 125 Query: 121 VPINKPGVFNYVRYEPLGVVVAITPWNSPLALTAWKMAPALACGNTIVVKPSEFTSPPLL 180 +PI+KP FNY R EPLGV V ITPWNSPL L ++K+APALA GNT V KPSEFTS L Sbjct: 126 IPIDKPETFNYTRNEPLGVCVGITPWNSPLLLLSYKLAPALAAGNTFVAKPSEFTSASTL 185 Query: 181 ELAALASEAGFPPGVINVVSGYGNEIGAALINHPRVAKIAFTGGDIGGQKVAEAAAKNFK 240 E A L +AGFPPGV NVV+G+G ++G L H VAKIAFTG + G+K+ E AA+NFK Sbjct: 186 EFAKLVEQAGFPPGVFNVVTGFGADVGETLTTHKHVAKIAFTGSEGTGRKIGELAARNFK 245 Query: 241 KITLELGGKSANIVFADADFEQAINGAIAGVFGAAGQTCMAGSRLLVERSIHDKFVARLI 300 K+TLELGGKS +IVFADA+ + A+NG I+G+F A GQTC+AGSRLLVE IHD+ + ++I Sbjct: 246 KVTLELGGKSPHIVFADAEIDNAVNGVISGIFAATGQTCIAGSRLLVESKIHDQVLEKVI 305 Query: 301 EVAGAARIGNPADSETQVGPIATRSQYEKILGYIEIAKQDGATCVLGGNALSGAQYGQGQ 360 +A AR+G+P + TQVGP+ T Q EKILGYI+IAK +GA C+LGG S ++ G G Sbjct: 306 ALAKTARMGDPLSTSTQVGPVTTPPQLEKILGYIDIAKGEGAECLLGGARPSNSELGNGW 365 Query: 361 FVAPTIFTNVRNDMRIAREEVFGPILSVIPFDSVEEALEIANDTDFGLAAAVWTTDLHKA 420 FV PTIF VRN MRIA+EEVFGP+L+VIPFD+ EEA+ IANDT++GLAA WT D+ + Sbjct: 366 FVEPTIFAGVRNSMRIAQEEVFGPVLAVIPFDTEEEAIHIANDTNYGLAAGFWTQDMRRM 425 Query: 421 IYCSDRIEAGTVWVNNYRATSFTTPFGGYKRSGVGREGGLEGAQEYMQAKSVWITTQPNK 480 + S I+AGTVWVN YR S+ +P GGYK SG+GRE G+ Q Y+Q KSV I+T + Sbjct: 426 LRVSAAIQAGTVWVNTYRTISYMSPLGGYKHSGIGRENGMASIQNYLQTKSVMISTAESV 485 Query: 481 QNAFVL 486 N F++ Sbjct: 486 ANPFIM 491