BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0013.0156.p (298 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_002501946.1| NAD-binding 6-phosphogluconate dehydrogenase... 375 e-102 ref|YP_001767561.1| NAD-binding 6-phosphogluconate dehydrogenase... 372 e-101 ref|YP_001524808.1| 3-hydroxyisobutyrate dehydrogenase [Azorhizo... 345 7e-93 ref|YP_004443395.1| 3-hydroxyisobutyrate dehydrogenase [Agrobact... 342 5e-92 ref|YP_003896115.1| 2-hydroxy-3-oxopropionate reductase [Halomon... 340 1e-91 >ref|YP_002501946.1| NAD-binding 6-phosphogluconate dehydrogenase [Methylobacterium nodulans ORS 2060] gb|ACL61643.1| 6-phosphogluconate dehydrogenase NAD-binding [Methylobacterium nodulans ORS 2060] Length = 296 Score = 375 bits (963), Expect = e-102, Method: Compositional matrix adjust. Identities = 198/290 (68%), Positives = 239/290 (82%) Query: 9 TIGFIGTGIMGFPMARHLAQAGYRVQAWNRTPDKARRLSAFGAEVIAEAGDVIRDADALV 68 TIGF+GTGIMG PMAR+L +AG+ VQ WNR+P KA L+A GA + A+ D RDADA++ Sbjct: 5 TIGFLGTGIMGAPMARNLCKAGHAVQVWNRSPGKAAALAADGARIAADRRDAARDADAVI 64 Query: 69 CMLSSGPDCDALLLGEQGLIAGMRAGSLLVVMSSIPVETARHQAQQAAARGVAYVDAPVS 128 CM+SSGP CD LLLG +G+IA MR GS+L VMSSIPVETAR QA+ AAA G+ YVDAPVS Sbjct: 65 CMVSSGPVCDELLLGPEGVIAAMRQGSVLAVMSSIPVETARRQAEIAAASGILYVDAPVS 124 Query: 129 GGEKGAIEASLAIMAGGTVQAYEQALPLLEKMGRPTHVGPAGSGELAKLVNQMMVANNIA 188 GGE GAI A+LAIM GG+ +A+ + P+L MGRPTHVGPAGSG+LAKL NQ +VA+ I Sbjct: 125 GGEAGAIAATLAIMTGGSPEAFGRIRPVLAAMGRPTHVGPAGSGQLAKLANQAIVASTIV 184 Query: 189 SVAEALLLAERGGADPAKVREALLGGFADSTILRQHALRMISGDFAPGGPARYQVKDTGT 248 +VAEA+ ERGGADPAKVREALLGGFADSTIL+QHALRMI+ DF PGGPA+YQ+KDTGT Sbjct: 185 TVAEAITFVERGGADPAKVREALLGGFADSTILKQHALRMIARDFTPGGPAKYQLKDTGT 244 Query: 249 AIRFAASVGLDLPMLNKADRLFSDMLDHGDGDLDHSGVIRELRRRNRLPV 298 A+ AA++GLDLP+L+ DRLFSD+++ GDG+LDHS +IREL RRN L V Sbjct: 245 ALAHAATLGLDLPVLSLVDRLFSDLIESGDGELDHSAIIRELWRRNGLDV 294 >ref|YP_001767561.1| NAD-binding 6-phosphogluconate dehydrogenase [Methylobacterium sp. 4-46] gb|ACA15127.1| 6-phosphogluconate dehydrogenase NAD-binding [Methylobacterium sp. 4-46] Length = 297 Score = 372 bits (956), Expect = e-101, Method: Compositional matrix adjust. Identities = 198/296 (66%), Positives = 235/296 (79%), Gaps = 3/296 (1%) Query: 1 MTAAAKIKTIGFIGTGIMGFPMARHLAQAGYRVQAWNRTPDKARRLSAFGAEVIAEAGDV 60 MT+AA TIGF+GTG+MG PMAR L AG+ V+ WNRTPDKA L A GA V + D Sbjct: 1 MTSAA---TIGFLGTGLMGAPMARRLCAAGHAVRVWNRTPDKAAALVAEGARVAQDPRDA 57 Query: 61 IRDADALVCMLSSGPDCDALLLGEQGLIAGMRAGSLLVVMSSIPVETARHQAQQAAARGV 120 R+ADA++CM+SSGP D +LLG +G +A MR GS+L VMSSIPVETAR QA AAA G+ Sbjct: 58 AREADAVICMVSSGPVSDEVLLGPEGALAAMRPGSVLAVMSSIPVETARRQAGIAAAAGL 117 Query: 121 AYVDAPVSGGEKGAIEASLAIMAGGTVQAYEQALPLLEKMGRPTHVGPAGSGELAKLVNQ 180 YVDAPVSGGE GA+ +LAIMAGG+ A+ + P+L MGRPTHVGPAGSG+LAKL NQ Sbjct: 118 LYVDAPVSGGEAGAVAGTLAIMAGGSPDAFARIRPILAAMGRPTHVGPAGSGQLAKLANQ 177 Query: 181 MMVANNIASVAEALLLAERGGADPAKVREALLGGFADSTILRQHALRMISGDFAPGGPAR 240 +VA+ I +VAEA+ ERGGADPAKVREALLGGFADSTIL+QHALRMI FAPGGPA+ Sbjct: 178 AIVASTIVTVAEAITFVERGGADPAKVREALLGGFADSTILKQHALRMIERTFAPGGPAK 237 Query: 241 YQVKDTGTAIRFAASVGLDLPMLNKADRLFSDMLDHGDGDLDHSGVIRELRRRNRL 296 YQ+KDTGTA+ AAS+GLDLP+L+ DRLF+ ++ HGDGDLDHS VIRE+RRRN L Sbjct: 238 YQLKDTGTALAHAASLGLDLPVLSLVDRLFAGLVAHGDGDLDHSAVIREIRRRNGL 293 >ref|YP_001524808.1| 3-hydroxyisobutyrate dehydrogenase [Azorhizobium caulinodans ORS 571] dbj|BAF87890.1| 3-hydroxyisobutyrate dehydrogenase [Azorhizobium caulinodans ORS 571] Length = 301 Score = 345 bits (884), Expect = 7e-93, Method: Compositional matrix adjust. Identities = 178/289 (61%), Positives = 220/289 (76%) Query: 6 KIKTIGFIGTGIMGFPMARHLAQAGYRVQAWNRTPDKARRLSAFGAEVIAEAGDVIRDAD 65 ++ IGF+GTGIMG PMAR+LA+AG+ V AWNR+ KAR L A G A + +R A+ Sbjct: 2 TLQRIGFLGTGIMGGPMARNLARAGFEVTAWNRSSGKARALEADGVRSAPTAHEAVRAAE 61 Query: 66 ALVCMLSSGPDCDALLLGEQGLIAGMRAGSLLVVMSSIPVETARHQAQQAAARGVAYVDA 125 ++CMLSSGP CD LLG G+I+ M G+ LVVMSSIPVETA QA+ AA RG+ YVDA Sbjct: 62 VVICMLSSGPVCDEFLLGADGMISAMAPGATLVVMSSIPVETAEAQARAAAERGLLYVDA 121 Query: 126 PVSGGEKGAIEASLAIMAGGTVQAYEQALPLLEKMGRPTHVGPAGSGELAKLVNQMMVAN 185 PVSGGEKGAI SLAIMAGG +A + P+L MGR HVGPAG+G+L KL+NQ +VA+ Sbjct: 122 PVSGGEKGAIAGSLAIMAGGPAEAVARVTPVLAAMGRAVHVGPAGTGQLCKLINQGIVAS 181 Query: 186 NIASVAEALLLAERGGADPAKVREALLGGFADSTILRQHALRMISGDFAPGGPARYQVKD 245 + ++AEA+ LA +GGADP KVREALLGGFADSTIL+QHALRM +GDF PGGPA+YQ+KD Sbjct: 182 TLVAMAEAMTLARQGGADPLKVREALLGGFADSTILKQHALRMATGDFVPGGPAKYQLKD 241 Query: 246 TGTAIRFAASVGLDLPMLNKADRLFSDMLDHGDGDLDHSGVIRELRRRN 294 T TA+ AA +GL LPML+ D +F ++ +GDGDLDHS VIRE+ R N Sbjct: 242 TRTALAHAAHLGLSLPMLSLTDSMFEALVANGDGDLDHSAVIREIWRAN 290 >ref|YP_004443395.1| 3-hydroxyisobutyrate dehydrogenase [Agrobacterium sp. H13-3] gb|ADY66304.1| 3-hydroxyisobutyrate dehydrogenase [Agrobacterium sp. H13-3] Length = 300 Score = 342 bits (876), Expect = 5e-92, Method: Compositional matrix adjust. Identities = 174/288 (60%), Positives = 220/288 (76%) Query: 7 IKTIGFIGTGIMGFPMARHLAQAGYRVQAWNRTPDKARRLSAFGAEVIAEAGDVIRDADA 66 I+ I IGTGIMG PMAR LA+AG+ V+AWNR+ +KA L+A G + A A + + +AD Sbjct: 4 IREIAVIGTGIMGAPMARRLAEAGFSVKAWNRSAEKAAVLAAKGVQPTATAAEAVAEADV 63 Query: 67 LVCMLSSGPDCDALLLGEQGLIAGMRAGSLLVVMSSIPVETARHQAQQAAARGVAYVDAP 126 ++CMLSSGP CD +LLG G+++ M+ G+ L+VMSSIPV++AR QA+ A A GVAYVDAP Sbjct: 64 VLCMLSSGPVCDEVLLGASGVVSTMKPGAFLLVMSSIPVDSAREQAEAAKAHGVAYVDAP 123 Query: 127 VSGGEKGAIEASLAIMAGGTVQAYEQALPLLEKMGRPTHVGPAGSGELAKLVNQMMVANN 186 VSGGEKGA E +LAIMAGG + + PLL +GR THVGP G G LAKL NQ++VA+ Sbjct: 124 VSGGEKGATEGTLAIMAGGEQRDVDALRPLLNCLGRVTHVGPVGCGSLAKLANQLIVAST 183 Query: 187 IASVAEALLLAERGGADPAKVREALLGGFADSTILRQHALRMISGDFAPGGPARYQVKDT 246 I +VAEAL L E GGADPA+VR+ALLGGFA+ST+ RQH RM+ GDF PGGPA+YQ+KDT Sbjct: 184 ICAVAEALTLVEAGGADPAQVRQALLGGFAESTVFRQHGKRMVEGDFRPGGPAKYQLKDT 243 Query: 247 GTAIRFAASVGLDLPMLNKADRLFSDMLDHGDGDLDHSGVIRELRRRN 294 TA+ FA S GL LP+ + DRLF M++HG G+LDHSGVI E++R N Sbjct: 244 STALAFAKSRGLKLPVGEEVDRLFRSMVEHGAGELDHSGVILEVKRMN 291 >ref|YP_003896115.1| 2-hydroxy-3-oxopropionate reductase [Halomonas elongata DSM 2581] emb|CBV40930.1| 2-hydroxy-3-oxopropionate reductase [Halomonas elongata DSM 2581] Length = 298 Score = 340 bits (873), Expect = 1e-91, Method: Compositional matrix adjust. Identities = 177/293 (60%), Positives = 219/293 (74%), Gaps = 1/293 (0%) Query: 7 IKTIGFIGTGIMGFPMARHLAQAGYRVQAWNRTPDKARRLSAFG-AEVIAEAGDVIRDAD 65 I+TIG +GTGIMG PMA LA+AG+ ++ WNR+ +KA L+ G ++ E D D Sbjct: 4 IRTIGVLGTGIMGGPMAARLARAGWPLKVWNRSREKAMALADAGDVTLVCEPHAAATDVD 63 Query: 66 ALVCMLSSGPDCDALLLGEQGLIAGMRAGSLLVVMSSIPVETARHQAQQAAARGVAYVDA 125 AL+ MLSSGP C+ +LLGE G + MR GSLL+VMSSIPV TAR QA A +AY+DA Sbjct: 64 ALIVMLSSGPVCNEILLGEHGALTAMRPGSLLLVMSSIPVGTARQQAGAARRHDIAYLDA 123 Query: 126 PVSGGEKGAIEASLAIMAGGTVQAYEQALPLLEKMGRPTHVGPAGSGELAKLVNQMMVAN 185 PVSGGE+GAIE +LAIM GG A+ +A LL +G P HVGP G G+LAKL NQ++VAN Sbjct: 124 PVSGGERGAIEGNLAIMVGGGASAFARAESLLGVLGSPVHVGPEGCGQLAKLANQLIVAN 183 Query: 186 NIASVAEALLLAERGGADPAKVREALLGGFADSTILRQHALRMISGDFAPGGPARYQVKD 245 IA+VAEALLLAERGGADPA+V EAL GGFADSTILR H RM+ G PGGPA++Q KD Sbjct: 184 GIATVAEALLLAERGGADPARVCEALQGGFADSTILRVHGQRMLEGYHEPGGPAKWQSKD 243 Query: 246 TGTAIRFAASVGLDLPMLNKADRLFSDMLDHGDGDLDHSGVIRELRRRNRLPV 298 T TA+ FA S+ L+LP+ DRLF+++++HGDG+LDHS +IRELRR NRLPV Sbjct: 244 TRTAMAFADSLALELPVSRLVDRLFNELVEHGDGNLDHSALIRELRRINRLPV 296