BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0013.0041.p (269 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003778085.1| diguanylate cyclase/phosphodiesterase with P... 278 5e-73 ref|YP_324643.1| diguanylate cyclase [Anabaena variabilis ATCC 2... 155 6e-36 ref|ZP_08825478.1| diguanylate cyclase [Thiorhodococcus drewsii ... 151 1e-34 ref|ZP_08824988.1| diguanylate cyclase [Thiorhodococcus drewsii ... 145 4e-33 ref|YP_001867593.1| diguanylate cyclase [Nostoc punctiforme PCC ... 145 5e-33 >ref|YP_003778085.1| diguanylate cyclase/phosphodiesterase with PAS/PAC sensor domain-containing protein [Herbaspirillum seropedicae SmR1] gb|ADJ66177.1| diguanylate cyclase/phosphodiesterase with PAS/PAC sensor domain protein [Herbaspirillum seropedicae SmR1] Length = 573 Score = 278 bits (711), Expect = 5e-73, Method: Compositional matrix adjust. Identities = 137/232 (59%), Positives = 180/232 (77%), Gaps = 1/232 (0%) Query: 3 IARSVAEN-SGNFVSYRDGDNREQLAAFAPVPRTSWMVVNVTPLNALNAEVRSIRNKIIL 61 I S+A+ +F++Y D AA A +P TSW V ++TP + LNA+ RS+R+KII Sbjct: 249 ITESLAQGRDSDFIAYVGADKTPYYAAIARLPHTSWWVASITPSDRLNADTRSVRDKIIA 308 Query: 62 IGVLCFILALVLSFIIARSISLPLKQLVGVMKATRTGNYLIRMDYEGKDEITELSQRFND 121 IG++CF ++L+LS +I+RSIS+PL++LV MK +G+ +R++ G DEI LS++FN+ Sbjct: 309 IGLVCFAVSLLLSALISRSISVPLQRLVAAMKEAGSGDTTVRVEQHGNDEIAVLSRKFNE 368 Query: 122 MASKVHQHNERLEELVAERTRELEQANRQLEALSATDSLTGIANRRRFDEALSGELRRAV 181 MA K+ Q+ E LEE V RTRELE+ANR+LEALSATD LTG+ANRRRFDEAL+ E+RRAV Sbjct: 369 MAGKLQQNREVLEEQVRLRTRELERANRKLEALSATDGLTGVANRRRFDEALANEMRRAV 428 Query: 182 RSQKPLALMMLDVDYFKNYNDRYGHLAGDDCLRTIARVMRASSRRATDLAAR 233 RS + LAL+MLDVDYFK YNDRYGHLAGD+CLR +ARV++ SSRRATDL AR Sbjct: 429 RSGQSLALLMLDVDYFKKYNDRYGHLAGDECLRIVARVLQKSSRRATDLVAR 480 >ref|YP_324643.1| diguanylate cyclase [Anabaena variabilis ATCC 29413] gb|ABA23748.1| Putative diguanylate cyclase (GGDEF domain) [Anabaena variabilis ATCC 29413] Length = 591 Score = 155 bits (392), Expect = 6e-36, Method: Compositional matrix adjust. Identities = 86/212 (40%), Positives = 121/212 (57%) Query: 22 NREQLAAFAPVPRTSWMVVNVTPLNALNAEVRSIRNKIILIGVLCFILALVLSFIIARSI 81 N+ L A A + W V+ PL A V + + + VL + +++F I + + Sbjct: 291 NQVNLIAIASLKYKPWSVLFAQPLVVALAPVEKQIHDAMFLFVLIASVVTIIAFAIGQLL 350 Query: 82 SLPLKQLVGVMKATRTGNYLIRMDYEGKDEITELSQRFNDMASKVHQHNERLEELVAERT 141 + P+ L ++ TGN IR DEI +L++ FN+MA ++ E LE+ V ERT Sbjct: 351 TRPIIYLTNIVFQFTTGNLNIRAKISSTDEIGQLAKSFNNMAFQLQTSFETLEQRVQERT 410 Query: 142 RELEQANRQLEALSATDSLTGIANRRRFDEALSGELRRAVRSQKPLALMMLDVDYFKNYN 201 EL AN++LE L D LT +ANRR FDE L E +R R Q+PL+L++ DVD FK+YN Sbjct: 411 AELVIANQKLEQLVNLDGLTQVANRRCFDERLKAEWKRLAREQQPLSLILFDVDKFKSYN 470 Query: 202 DRYGHLAGDDCLRTIARVMRASSRRATDLAAR 233 D YGHL GDDCL TIA+ ++ R DL AR Sbjct: 471 DYYGHLGGDDCLITIAQAVQQKLHRPADLLAR 502 >ref|ZP_08825478.1| diguanylate cyclase [Thiorhodococcus drewsii AZ1] gb|EGV27913.1| diguanylate cyclase [Thiorhodococcus drewsii AZ1] Length = 630 Score = 151 bits (381), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 96/225 (42%), Positives = 127/225 (56%), Gaps = 19/225 (8%) Query: 21 DNREQLAAFAPVPRTSWMVVNVTPLNALNAEVRSIRNKIILIGVLCFILALV-----LSF 75 D + A +P T ++ P + + ++ +G+L ++ +V L F Sbjct: 326 DTPGAIVAVGRIPETPAILTIHYPRALMRPAILQNLAVVVAVGLLTLLVEIVILRNILRF 385 Query: 76 IIARSISLPLKQLVGVMKATRTGNYLIRMDYEGKD-------EITELSQRFNDMASKVHQ 128 +AR PL+QL+ +ATR E KD EI +L++ F MA +V Sbjct: 386 QVAR----PLEQLI---RATRLLGSGTERKVEEKDLPTGSRDEIGDLARAFAGMAEQVQS 438 Query: 129 HNERLEELVAERTRELEQANRQLEALSATDSLTGIANRRRFDEALSGELRRAVRSQKPLA 188 LE V ERT ELE ANR+L A+S TDSLT IANRRRFD AL E RRA+RS L Sbjct: 439 ARAELESKVLERTLELEAANRKLAAMSTTDSLTDIANRRRFDAALEEEWRRAMRSGSSLT 498 Query: 189 LMMLDVDYFKNYNDRYGHLAGDDCLRTIARVMRASSRRATDLAAR 233 L M+DVD+FK YNDRYGH +GD CLR IARV+ +++RRA DL AR Sbjct: 499 LSMIDVDWFKKYNDRYGHQSGDACLRQIARVLESTARRAGDLVAR 543 >ref|ZP_08824988.1| diguanylate cyclase [Thiorhodococcus drewsii AZ1] gb|EGV28437.1| diguanylate cyclase [Thiorhodococcus drewsii AZ1] Length = 593 Score = 145 bits (367), Expect = 4e-33, Method: Compositional matrix adjust. Identities = 93/231 (40%), Positives = 128/231 (55%), Gaps = 18/231 (7%) Query: 19 DGDNREQLAAFAPV--PRT---SWMVVNVTPLNALNAEVRSIRNKIILIGVLCFILALVL 73 D DNR L A V P T SW +V P+ V +R ++L+GV +L + L Sbjct: 262 DWDNRRYLTAQTIVRAPGTDTLSWHIVVRQPVEVALGSVADLRYHMLLLGVFMSLLLVFL 321 Query: 74 SFIIARSISLPLKQLVGVM----KATRTGNYLIRMDYEGKDEITELSQRFNDMASKV--- 126 + +A S S PL++L V T N+ +R ++ + E+ EL M + + Sbjct: 322 ANRVAISFSQPLQKLAQVAYRIDHGEETFNFTVR-PFKLR-ELNELVSSIRGMTATLFER 379 Query: 127 ----HQHNERLEELVAERTRELEQANRQLEALSATDSLTGIANRRRFDEALSGELRRAVR 182 Q N LE+ + ERT +L +AN QL AL+ TD LTG+ANRRRFDE L E RA R Sbjct: 380 KHALEQVNRSLEDRIRERTAQLREANLQLAALATTDGLTGVANRRRFDEILEQEWERAKR 439 Query: 183 SQKPLALMMLDVDYFKNYNDRYGHLAGDDCLRTIARVMRASSRRATDLAAR 233 + PL+L+M+D+D+FK YND YGH GD CLR + R++R S RA D AR Sbjct: 440 AGTPLSLLMIDIDFFKQYNDHYGHQTGDTCLREVGRLVRDSIHRAGDAVAR 490 >ref|YP_001867593.1| diguanylate cyclase [Nostoc punctiforme PCC 73102] gb|ACC82650.1| diguanylate cyclase [Nostoc punctiforme PCC 73102] Length = 597 Score = 145 bits (367), Expect = 5e-33, Method: Compositional matrix adjust. Identities = 86/220 (39%), Positives = 122/220 (55%), Gaps = 9/220 (4%) Query: 22 NREQLAAFAPVPRTSWMVVNVTPLNALNAEV-RSIRNKIILIGVLCFILALVLSFIIARS 80 N+ L A A + W V+ PL A V + I + + L ++ ++ ++ +F I + Sbjct: 289 NQVNLIAIARLKYKPWSVLFAQPLTVALAPVEKQISDAMFLFAIIASVVTII-AFAIGQV 347 Query: 81 ISLPLKQLVGVMKATRTGNYLIRMDYEGKDEITELSQRFNDMASKVHQHNERLEELVAER 140 ++ P+ L ++ G+ IR KDEI +L++ FN+MA ++ E LE+ V ER Sbjct: 348 LTKPIIYLTNIVFQFTAGHLDIRAKISSKDEIGQLAKSFNNMALQLQTSLETLEQRVQER 407 Query: 141 TREL-------EQANRQLEALSATDSLTGIANRRRFDEALSGELRRAVRSQKPLALMMLD 193 T EL E AN +LE L D LT +ANRR FD L E + R Q+PL+L++LD Sbjct: 408 TAELVIAKEKAEDANHKLEQLVNLDGLTQVANRRCFDGRLQEEWKCLAREQRPLSLILLD 467 Query: 194 VDYFKNYNDRYGHLAGDDCLRTIARVMRASSRRATDLAAR 233 VD FK YND YGHL GDDCL TIA+ M+ R DL AR Sbjct: 468 VDKFKLYNDYYGHLGGDDCLITIAQTMQQVVHRPADLVAR 507