BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0013.0012.p (581 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003776509.1| propionyl-CoA ligase [Herbaspirillum seroped... 976 0.0 ref|YP_004754177.1| propionate--CoA ligase [Collimonas fungivora... 939 0.0 ref|YP_001101497.1| propionyl-CoA synthetase [Herminiimonas arse... 912 0.0 ref|YP_001355180.1| propionyl-CoA synthetase [Janthinobacterium ... 902 0.0 ref|YP_004729233.1| propionate--CoA ligase [Salmonella bongori N... 862 0.0 >ref|YP_003776509.1| propionyl-CoA ligase [Herbaspirillum seropedicae SmR1] gb|ADJ64601.1| propionyl-CoA ligase protein [Herbaspirillum seropedicae SmR1] Length = 628 Score = 976 bits (2522), Expect = 0.0, Method: Compositional matrix adjust. Identities = 462/578 (79%), Positives = 511/578 (88%), Gaps = 4/578 (0%) Query: 1 MSYASFYQQSIDDPDTFWANEARRIDWHAPFTKTRDYTRPPFARWFIGGETNLCHNAVDR 60 M Y FY+QS++ P+ FWA EA+RI W PF++T DY+RPPFARWFI G+TNLCHNAVDR Sbjct: 1 MQYEQFYRQSVEQPEAFWAQEAQRIHWQQPFSRTLDYSRPPFARWFIDGQTNLCHNAVDR 60 Query: 61 HLAQRADQAALIAVSTETNTEKTYTFRELHREVSAMAAIMLSLGVKRGDRVLIYMPMIAE 120 HL +RA QAALIA+STETN+E+ YT+ EL +EV AMAA M +LGV+RGDRVLIYMPMIAE Sbjct: 61 HLPERAQQAALIAISTETNSERVYTYAELQQEVMAMAASMQALGVQRGDRVLIYMPMIAE 120 Query: 121 AVFAMLACARIGAVHSVVFGGFASTSLATRIDDAQPTLIVSADAGSRGGRVVAYKGLLDE 180 AVFAMLACARIGAVHSVVFGGFAS SLA+RIDDAQP LIVSADAGSRGG+V+ YKGLLDE Sbjct: 121 AVFAMLACARIGAVHSVVFGGFASNSLASRIDDAQPRLIVSADAGSRGGKVIPYKGLLDE 180 Query: 181 AIRLAQHKPAHVLLTDRGLAEMPRTTGRDVDYTSLRAQYLDADVPVAWLESNEPSYILYT 240 AI +AQH+P HVLL DRGLA M RT RDVDY LR Q+L VPV WLESN SYILYT Sbjct: 181 AIAMAQHRPQHVLLVDRGLAPMARTAQRDVDYAPLRTQHLGQQVPVTWLESNASSYILYT 240 Query: 241 SGTTGKPKGVQRDVGGYAVALAASMSYIFCGNPGETYFCTSDIGWVVGHSYIVYGPLMAG 300 SGTTGKPKGVQRDVGGYAVALA+SM +IFCG PGETYFCTSDIGWVVGHSYIVYGPL+AG Sbjct: 241 SGTTGKPKGVQRDVGGYAVALASSMQHIFCGQPGETYFCTSDIGWVVGHSYIVYGPLIAG 300 Query: 301 MATILYEGLPVLAGDKPDGGIWWSLVEKYKVTRMFSSPTAIRVLKKQPAECMTRYDLSSL 360 MAT+LYEGLP+ +PD GIWWS+VEKYKVTRMFS+PTAIRVLKKQP ECM RYD SSL Sbjct: 301 MATVLYEGLPI----RPDAGIWWSIVEKYKVTRMFSAPTAIRVLKKQPPECMERYDTSSL 356 Query: 361 KSLYLAGEPLDETTSNWISGALGVPVIDNYWQTESGWPILSIAKGVDDKPTRLGSPGVPL 420 K+LYLAGEPLDETTS+WISGAL VPVIDNYWQTESGWPI+SIAKG+DDKPTRLGSPGVP+ Sbjct: 357 KALYLAGEPLDETTSSWISGALKVPVIDNYWQTESGWPIISIAKGIDDKPTRLGSPGVPM 416 Query: 421 YGYKMHIMNESTGELCGVNEKGVVVIEGPLPPGCMQTVYRDDERFVNTYWSNFRTQVYST 480 GY++ I++E+TGE CG ++KGVV IEGPLPPGCMQTVY DDERFVNTYW + +VYST Sbjct: 417 PGYRLAILDEATGEPCGPDQKGVVAIEGPLPPGCMQTVYGDDERFVNTYWRSLPREVYST 476 Query: 481 FDWGIRDEDGYYFILGRTDDVINVAGHRLGTREIEESISSHANVSEVAVVGVDDKLKGQV 540 FDWGIRD+DGYYFILGRTDDVINVAGHRLGTREIEESISSH NVSEVAVVGV+DKLKGQV Sbjct: 477 FDWGIRDKDGYYFILGRTDDVINVAGHRLGTREIEESISSHPNVSEVAVVGVEDKLKGQV 536 Query: 541 AIAFVIPKQADAVATAEGRQALEAEIMRVVDKQIGAVG 578 A AF IPKQA +AT E R+ALEAEIM VVDKQIGAVG Sbjct: 537 AFAFAIPKQAYTIATPEQRKALEAEIMAVVDKQIGAVG 574 >ref|YP_004754177.1| propionate--CoA ligase [Collimonas fungivorans Ter331] gb|AEK63354.1| Propionate--CoA ligase [Collimonas fungivorans Ter331] Length = 655 Score = 939 bits (2428), Expect = 0.0, Method: Compositional matrix adjust. Identities = 447/585 (76%), Positives = 510/585 (87%), Gaps = 16/585 (2%) Query: 1 MSYASFYQQSIDDPDTFWANEARRIDWHAPFTKTRDYTRPPFARWFIGGETNLCHNAVDR 60 MS+A+FYQ+S+DDP FWA +ARRIDWH PF++ D +RPPFARWF+ G TNLCHNAVDR Sbjct: 26 MSFATFYQRSVDDPSAFWAEQARRIDWHHPFSQVLDGSRPPFARWFVDGATNLCHNAVDR 85 Query: 61 HLAQRADQAALIAVSTETNTEKTYTFRELHREVSAMAAIMLSLGVKRGDRVLIYMPMIAE 120 +A R +QAALIAVSTETNTEKTY+FRELH EV+ AAIM +LGV RGDRVLIYMPMIAE Sbjct: 86 WVATRGEQAALIAVSTETNTEKTYSFRELHAEVNRTAAIMQALGVGRGDRVLIYMPMIAE 145 Query: 121 AVFAMLACARIGAVHSVVFGGFASTSLATRIDDAQPTLIVSADAGSRGGRVVAYKGLLDE 180 AVFAMLACARIGA+HSVVFGGFAS SLA+RIDDA P L+VSADAGSR G+++ YKGLLDE Sbjct: 146 AVFAMLACARIGAIHSVVFGGFASNSLASRIDDATPKLVVSADAGSRAGKILPYKGLLDE 205 Query: 181 AIRLAQHKPAHVLLTDRGLAEMPRTTGRDVDYTSLRAQYLDADVPVAWLESNEPSYILYT 240 AI+LA+HKPAHVL+ DRGLA M GRDVDY R ++DA VP WLESNE SYILYT Sbjct: 206 AIKLARHKPAHVLMVDRGLAAMATVAGRDVDYAEQRRLHMDAKVPAVWLESNEASYILYT 265 Query: 241 SGTTGKPKGVQRDVGGYAVALAASMSYIFCGNPGETYFCTSDIGWVVGHSYIVYGPLMAG 300 SGTTGKPKGVQRDVGGYAVALA SM IFC PG T+FCTSDIGWVVGHSYIVYGPL+AG Sbjct: 266 SGTTGKPKGVQRDVGGYAVALATSMDTIFCSKPGGTFFCTSDIGWVVGHSYIVYGPLIAG 325 Query: 301 MATILYEGLPVLAGDKPDGGIWWSLVEKYKVTRMFSSPTAIRVLKKQPAECMTRYDLSSL 360 MAT+LYEGLP+ +PDGG+WWS+VEKYKVTRMFS+PTAIRVLKKQP E M +YDLSSL Sbjct: 326 MATVLYEGLPI----RPDGGVWWSIVEKYKVTRMFSAPTAIRVLKKQPPELMKKYDLSSL 381 Query: 361 KSLYLAGEPLDETTSNWISGALGVPVIDNYWQTESGWPILSIAKGVDDKPTRLGSPGVPL 420 ++LYLAGEPLDETTS+WIS ALGVP++DNYWQTESGWPI++IA+ V+DKP++LGSPGVP+ Sbjct: 382 QALYLAGEPLDETTSSWISSALGVPIVDNYWQTESGWPIMTIARNVEDKPSKLGSPGVPM 441 Query: 421 YGYKMHIMNESTGELCGVNEKGVVVIEGPLPPGCMQTVYRDDERFVNTYWSNFRTQV--- 477 YGYK+ ++NE++GELCG NEKGVVVIE PLPPGCMQT+Y DD+R ++TYW+ TQV Sbjct: 442 YGYKVRLLNEASGELCGANEKGVVVIEWPLPPGCMQTIYGDDQRCIDTYWA---TQVPGS 498 Query: 478 ----YSTFDWGIRDEDGYYFILGRTDDVINVAGHRLGTREIEESISSHANVSEVAVVGVD 533 YSTFDWGIRD+DGYYFILGRTDDVINVAGHRLGTREIEESISSH NVSEVAVVG++ Sbjct: 499 PNPAYSTFDWGIRDDDGYYFILGRTDDVINVAGHRLGTREIEESISSHPNVSEVAVVGIE 558 Query: 534 DKLKGQVAIAFVIPKQADAVATAEGRQALEAEIMRVVDKQIGAVG 578 DKLKGQVA+AFVIPK AV TA+GR ALEAEIM VD+QIG+VG Sbjct: 559 DKLKGQVAVAFVIPKA--AVDTAQGRAALEAEIMGTVDRQIGSVG 601 >ref|YP_001101497.1| propionyl-CoA synthetase [Herminiimonas arsenicoxydans] emb|CAL63376.1| Propionate--CoA ligase (Propionyl-CoA synthetase) [Herminiimonas arsenicoxydans] Length = 634 Score = 912 bits (2357), Expect = 0.0, Method: Compositional matrix adjust. Identities = 426/577 (73%), Positives = 494/577 (85%), Gaps = 4/577 (0%) Query: 2 SYASFYQQSIDDPDTFWANEARRIDWHAPFTKTRDYTRPPFARWFIGGETNLCHNAVDRH 61 +Y +FY++SIDDP TFWA +A+RI+W+ PFT+T DY PPF +WF+GGET+LC+NAVDRH Sbjct: 7 AYDAFYRRSIDDPHTFWAEQAQRIEWNKPFTRTLDYDHPPFTKWFVGGETSLCYNAVDRH 66 Query: 62 LAQRADQAALIAVSTETNTEKTYTFRELHREVSAMAAIMLSLGVKRGDRVLIYMPMIAEA 121 LA RADQ ALIA+STET++EK YTF +LH EV+ AA+M SLGV +GDRVLIYMPM+AEA Sbjct: 67 LATRADQPALIAISTETDSEKVYTFAQLHAEVNRCAAMMQSLGVSQGDRVLIYMPMVAEA 126 Query: 122 VFAMLACARIGAVHSVVFGGFASTSLATRIDDAQPTLIVSADAGSRGGRVVAYKGLLDEA 181 FAMLACARIGA+HSVVFGGFAS SLATRIDDA P LI+SADAGSRG V+ YK LLDEA Sbjct: 127 AFAMLACARIGAIHSVVFGGFASNSLATRIDDATPVLILSADAGSRGCHVMPYKSLLDEA 186 Query: 182 IRLAQHKPAHVLLTDRGLAEMPRTTGRDVDYTSLRAQYLDADVPVAWLESNEPSYILYTS 241 I LA+HKP HVL+ +RGLA M GRD+DY +LR +++DA VPV WLESN PSYILYTS Sbjct: 187 IVLAEHKPTHVLMVNRGLAPMQTVAGRDIDYATLREKHMDAAVPVVWLESNAPSYILYTS 246 Query: 242 GTTGKPKGVQRDVGGYAVALAASMSYIFCGNPGETYFCTSDIGWVVGHSYIVYGPLMAGM 301 GTTGKPKGV RDVGGYAVAL SM IFCG GET+FCTSDIGWVVGHSYI+YGPL+AGM Sbjct: 247 GTTGKPKGVVRDVGGYAVALTTSMDLIFCGKAGETFFCTSDIGWVVGHSYIIYGPLLAGM 306 Query: 302 ATILYEGLPVLAGDKPDGGIWWSLVEKYKVTRMFSSPTAIRVLKKQPAECMTRYDLSSLK 361 AT+LYEGLP+ +PD IWWS+VEKYKVTRM S+PTAIRVLKKQP E + ++DLSSLK Sbjct: 307 ATVLYEGLPI----RPDASIWWSIVEKYKVTRMSSAPTAIRVLKKQPLELLKKHDLSSLK 362 Query: 362 SLYLAGEPLDETTSNWISGALGVPVIDNYWQTESGWPILSIAKGVDDKPTRLGSPGVPLY 421 +LYLAGEPLD+TTS WISG L VPVIDNYWQTE+GWPI+SIAKGV DKPTR GSPG+PLY Sbjct: 363 ALYLAGEPLDQTTSEWISGVLNVPVIDNYWQTETGWPIISIAKGVGDKPTRSGSPGLPLY 422 Query: 422 GYKMHIMNESTGELCGVNEKGVVVIEGPLPPGCMQTVYRDDERFVNTYWSNFRTQVYSTF 481 GYK I+NE +GE C NEKGVV+IEGPLPPGC+QT+Y DD+RFV+TYW NF+ + YSTF Sbjct: 423 GYKTKIINEISGEECAANEKGVVIIEGPLPPGCLQTLYGDDQRFVSTYWRNFKREAYSTF 482 Query: 482 DWGIRDEDGYYFILGRTDDVINVAGHRLGTREIEESISSHANVSEVAVVGVDDKLKGQVA 541 DWGIRD DGYYFILGRTDDVINVAGHRLGTREIEESISSH NVSEVAVVGV++ +KGQ A Sbjct: 483 DWGIRDADGYYFILGRTDDVINVAGHRLGTREIEESISSHGNVSEVAVVGVENPIKGQCA 542 Query: 542 IAFVIPKQADAVATAEGRQALEAEIMRVVDKQIGAVG 578 +AFVI K A A+ E + LEAEIM+VVDK++G++G Sbjct: 543 VAFVILKNAALAASPEEAKKLEAEIMKVVDKRLGSIG 579 >ref|YP_001355180.1| propionyl-CoA synthetase [Janthinobacterium sp. Marseille] gb|ABR89021.1| propionyl-CoA synthetase [Janthinobacterium sp. Marseille] Length = 634 Score = 902 bits (2330), Expect = 0.0, Method: Compositional matrix adjust. Identities = 435/577 (75%), Positives = 499/577 (86%), Gaps = 4/577 (0%) Query: 2 SYASFYQQSIDDPDTFWANEARRIDWHAPFTKTRDYTRPPFARWFIGGETNLCHNAVDRH 61 +Y +FY+ S+DDP +FWA +A+RIDWH PF+KT DY +PPFA+WF+GGETNLC+NAVDRH Sbjct: 7 AYDAFYRLSVDDPHSFWATQAKRIDWHKPFSKTLDYDKPPFAKWFVGGETNLCYNAVDRH 66 Query: 62 LAQRADQAALIAVSTETNTEKTYTFRELHREVSAMAAIMLSLGVKRGDRVLIYMPMIAEA 121 LA RADQ AL+A+STET+TE TYT+ +LH EVS AA+M +LGV +GDRVLIYMPM+AEA Sbjct: 67 LATRADQPALVAISTETDTETTYTYAQLHAEVSRSAAMMQALGVGQGDRVLIYMPMVAEA 126 Query: 122 VFAMLACARIGAVHSVVFGGFASTSLATRIDDAQPTLIVSADAGSRGGRVVAYKGLLDEA 181 FAMLACARIGA+HSVVFGGFASTSLATRIDDA P LI+SADAGSRG V YK LLDEA Sbjct: 127 AFAMLACARIGAIHSVVFGGFASTSLATRIDDATPVLIISADAGSRGCHVTPYKCLLDEA 186 Query: 182 IRLAQHKPAHVLLTDRGLAEMPRTTGRDVDYTSLRAQYLDADVPVAWLESNEPSYILYTS 241 I LA+HKPAHVL+ DRGLA M GRDVDY +LR Q++DA VPVAWLESN PSYILYTS Sbjct: 187 IALAEHKPAHVLMLDRGLAPMKTIEGRDVDYATLRRQHMDAVVPVAWLESNAPSYILYTS 246 Query: 242 GTTGKPKGVQRDVGGYAVALAASMSYIFCGNPGETYFCTSDIGWVVGHSYIVYGPLMAGM 301 GTTGKPKGV RDVGGYAVALA SM IFCG PGET+FCTSDIGWVVGHSYI+YGPL+AGM Sbjct: 247 GTTGKPKGVLRDVGGYAVALATSMDLIFCGKPGETFFCTSDIGWVVGHSYIIYGPLLAGM 306 Query: 302 ATILYEGLPVLAGDKPDGGIWWSLVEKYKVTRMFSSPTAIRVLKKQPAECMTRYDLSSLK 361 TILYEGLP+ +PD IWWS+VEKYKVTRM S+PTAIRVLKKQP E + ++DLSSLK Sbjct: 307 TTILYEGLPI----RPDASIWWSIVEKYKVTRMSSAPTAIRVLKKQPLELLQKHDLSSLK 362 Query: 362 SLYLAGEPLDETTSNWISGALGVPVIDNYWQTESGWPILSIAKGVDDKPTRLGSPGVPLY 421 +LYLAGEPLD+TTS+WISG LGVPVIDNYWQTE+GWPI+S+AKGV DKPTR GSPG P+Y Sbjct: 363 ALYLAGEPLDQTTSDWISGVLGVPVIDNYWQTETGWPIISVAKGVGDKPTRSGSPGQPMY 422 Query: 422 GYKMHIMNESTGELCGVNEKGVVVIEGPLPPGCMQTVYRDDERFVNTYWSNFRTQVYSTF 481 GYK ++NE TGE C NEKGVV+IEGPLPPGC+QT+Y DD+RFV+TYW NF+ + YSTF Sbjct: 423 GYKAKVINEETGEECAPNEKGVVIIEGPLPPGCLQTLYGDDQRFVSTYWRNFKREAYSTF 482 Query: 482 DWGIRDEDGYYFILGRTDDVINVAGHRLGTREIEESISSHANVSEVAVVGVDDKLKGQVA 541 DWGIRD DGYYFILGRTDDVINVAGHRLGTREIEESISSHANVSEVAVVGV++ +KGQ A Sbjct: 483 DWGIRDADGYYFILGRTDDVINVAGHRLGTREIEESISSHANVSEVAVVGVENPIKGQCA 542 Query: 542 IAFVIPKQADAVATAEGRQALEAEIMRVVDKQIGAVG 578 +AFVI K A A A + + LEAEIM+VVDK++G +G Sbjct: 543 VAFVILKNAAAAADPDEARKLEAEIMKVVDKRLGPIG 579 >ref|YP_004729233.1| propionate--CoA ligase [Salmonella bongori NCTC 12419] emb|CCC29420.1| propionate--CoA ligase [Salmonella bongori NCTC 12419] Length = 628 Score = 862 bits (2228), Expect = 0.0, Method: Compositional matrix adjust. Identities = 406/578 (70%), Positives = 480/578 (83%), Gaps = 4/578 (0%) Query: 1 MSYASFYQQSIDDPDTFWANEARRIDWHAPFTKTRDYTRPPFARWFIGGETNLCHNAVDR 60 MS++ FYQ+SI++P+ FWA +ARRIDW PFT+T DY+ PPFARWF GG TNLCHNA+DR Sbjct: 1 MSFSEFYQRSINEPEQFWAEQARRIDWQQPFTQTLDYSNPPFARWFCGGTTNLCHNAIDR 60 Query: 61 HLAQRADQAALIAVSTETNTEKTYTFRELHREVSAMAAIMLSLGVKRGDRVLIYMPMIAE 120 L + D ALIAVS+ET E+T+TFR+L+ EV+ +A+++LSLGV+RGDRVL+YMPMIAE Sbjct: 61 WLDTQPDALALIAVSSETEEERTFTFRQLYDEVNVVASMLLSLGVRRGDRVLVYMPMIAE 120 Query: 121 AVFAMLACARIGAVHSVVFGGFASTSLATRIDDAQPTLIVSADAGSRGGRVVAYKGLLDE 180 A +LACARIGA+HSVVFGGFAS S+A RIDDA+P LIVSADAG+RGG+V+ YK LLDE Sbjct: 121 AHITLLACARIGAIHSVVFGGFASHSVAARIDDARPVLIVSADAGARGGKVIPYKKLLDE 180 Query: 181 AIRLAQHKPAHVLLTDRGLAEMPRTTGRDVDYTSLRAQYLDADVPVAWLESNEPSYILYT 240 A+ AQH+P HVLL DRGLA+M R GRDVD+ +LR + A VPVAWLESNE S ILYT Sbjct: 181 AVDQAQHQPKHVLLVDRGLAKMARVAGRDVDFATLREHHAGARVPVAWLESNESSCILYT 240 Query: 241 SGTTGKPKGVQRDVGGYAVALAASMSYIFCGNPGETYFCTSDIGWVVGHSYIVYGPLMAG 300 SGTTGKPKGVQRDVGGYAVALA SM +F G G +FC SDIGWVVGHSYIVY PL+AG Sbjct: 241 SGTTGKPKGVQRDVGGYAVALATSMDTLFGGKAGGVFFCASDIGWVVGHSYIVYAPLLAG 300 Query: 301 MATILYEGLPVLAGDKPDGGIWWSLVEKYKVTRMFSSPTAIRVLKKQPAECMTRYDLSSL 360 MATI+YEGLP PD G+WW +VEKY+V+RMFS+PTAIRVLKK P + +DLSSL Sbjct: 301 MATIVYEGLPTY----PDCGVWWKIVEKYRVSRMFSAPTAIRVLKKFPTAQIRNHDLSSL 356 Query: 361 KSLYLAGEPLDETTSNWISGALGVPVIDNYWQTESGWPILSIAKGVDDKPTRLGSPGVPL 420 + LYLAGEPLDE T+ W+SG LGVPVIDNYWQTESGWPI+++A+ +DD+P+RLGSPGVP+ Sbjct: 357 EVLYLAGEPLDEPTAAWVSGTLGVPVIDNYWQTESGWPIMALARTLDDRPSRLGSPGVPM 416 Query: 421 YGYKMHIMNESTGELCGVNEKGVVVIEGPLPPGCMQTVYRDDERFVNTYWSNFRTQVYST 480 YGY + ++NE TGE CG NEKG+VVIEGPLPPGC+QT++ DD RFVNTYWS F QVY+T Sbjct: 417 YGYNVQLLNEVTGEPCGANEKGMVVIEGPLPPGCIQTIWGDDARFVNTYWSLFTRQVYAT 476 Query: 481 FDWGIRDEDGYYFILGRTDDVINVAGHRLGTREIEESISSHANVSEVAVVGVDDKLKGQV 540 FDWGIRD DGYYFILGRTDDVINVAGHRLGTREIEESISS+ NV+EVAVVGV D LKGQV Sbjct: 477 FDWGIRDADGYYFILGRTDDVINVAGHRLGTREIEESISSYPNVAEVAVVGVKDALKGQV 536 Query: 541 AIAFVIPKQADAVATAEGRQALEAEIMRVVDKQIGAVG 578 A+AFVIPKQ+D++ E + E IM +VD QIG G Sbjct: 537 AVAFVIPKQSDSLEDREVAHSEEKAIMALVDSQIGNFG 574