BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0012.0148.p (466 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_004680889.1| aldehyde dehydrogenase AldA [Cupriavidus nec... 374 e-101 ref|YP_728899.1| aldehyde dehydrogenase, NAD-dependent [Ralstoni... 373 e-101 ref|YP_002007254.1| nad+ dependent betaine aldehyde dehydrogenas... 370 e-100 ref|ZP_07674483.1| aldehyde dehydrogenase (NAD) family protein [... 366 4e-99 ref|YP_001893019.1| Aldehyde Dehydrogenase [Ralstonia pickettii ... 366 6e-99 >ref|YP_004680889.1| aldehyde dehydrogenase AldA [Cupriavidus necator N-1] gb|AEI79657.1| aldehyde dehydrogenase AldA [Cupriavidus necator N-1] Length = 492 Score = 374 bits (959), Expect = e-101, Method: Compositional matrix adjust. Identities = 185/202 (91%), Positives = 191/202 (94%) Query: 205 FRTSGWAQKKPHERAIVLYRVAQLIRERGEALAQRQRLDNGKPITETRNLVGSAAATFQF 264 F TSGWAQ+KPHERA VLYRVA+LIR +GE LAQRQRLDNGKPI+ETR LV SAA TFQF Sbjct: 56 FLTSGWAQRKPHERAAVLYRVAELIRAQGEQLAQRQRLDNGKPISETRALVASAAGTFQF 115 Query: 265 FAAACETLEETITPMRGDNLTMSVYEAMGVVAAITPWNSPIASEAQKMAPALAAGNAVVV 324 FAAACETLEETITP RGD LTMSVYE MGVVAAITPWNSPIASEAQKMAPALAAGNAVVV Sbjct: 116 FAAACETLEETITPQRGDCLTMSVYEPMGVVAAITPWNSPIASEAQKMAPALAAGNAVVV 175 Query: 325 KPAEVTPLMALELARICEEAGVPKGLISVLPGKGSVIGDAITLHPLVKRVSFTGGTTTGK 384 KPAEVTPLMALELARICEEAGVPKGL+SVLPGKGSVIGDAIT HPLV+RVSFTGGTTTGK Sbjct: 176 KPAEVTPLMALELARICEEAGVPKGLVSVLPGKGSVIGDAITKHPLVRRVSFTGGTTTGK 235 Query: 385 HIAHIAADKMMPVSLELGGKSP 406 HIAHIAADKMMPVSLELGGKSP Sbjct: 236 HIAHIAADKMMPVSLELGGKSP 257 Score = 349 bits (895), Expect = 6e-94, Method: Compositional matrix adjust. Identities = 163/203 (80%), Positives = 181/203 (89%) Query: 1 MVFDDADIDHAVAGVLYGIFSSSGESCIAGSRLFVARSIYDSFMERLAAGAAALRVGDPA 60 MVFDDAD+DHAV GVLYGIFSSSGESCIAGSRLFVARS Y++F++RLAAGAA LRVGDPA Sbjct: 259 MVFDDADLDHAVNGVLYGIFSSSGESCIAGSRLFVARSQYEAFIDRLAAGAAHLRVGDPA 318 Query: 61 DERTQMGPLITARHREGIESYVSIGVADGGRIRTGGTRLAGDQFARGYYYAPTIIEGVTN 120 DERTQMGPLIT RHR+ IESYV+ GV +GG++RTGG R GY+Y PTIIEG+ N Sbjct: 319 DERTQMGPLITDRHRDSIESYVAAGVEEGGQLRTGGLRPDVAGLPNGYFYTPTIIEGLDN 378 Query: 121 DQRICQEEIFGPVLAAMPFDNEEDLIAQANDSVYALAAGIWTRDYKKAWRFGRAVQAGNV 180 + RICQEEIFGPVL A+PFD+E+DLIAQANDSVYALAAGIWTRDYK+AWR RAVQAGNV Sbjct: 379 NARICQEEIFGPVLVAIPFDDEDDLIAQANDSVYALAAGIWTRDYKRAWRVARAVQAGNV 438 Query: 181 WINTYKQFSISTPFGGWRDSGLG 203 WINTYKQFSI+TPFGGWRDSGLG Sbjct: 439 WINTYKQFSIATPFGGWRDSGLG 461 >ref|YP_728899.1| aldehyde dehydrogenase, NAD-dependent [Ralstonia eutropha H16] emb|CAJ95534.1| aldehyde dehydrogenase, NAD-dependent [Ralstonia eutropha H16] Length = 492 Score = 373 bits (957), Expect = e-101, Method: Compositional matrix adjust. Identities = 185/202 (91%), Positives = 191/202 (94%) Query: 205 FRTSGWAQKKPHERAIVLYRVAQLIRERGEALAQRQRLDNGKPITETRNLVGSAAATFQF 264 F TSGWAQ+KPHERA VLYRVA+LIR +GE LAQRQRLDNGKPI+ETR LV SAA TFQF Sbjct: 56 FLTSGWAQRKPHERAAVLYRVAELIRAQGEQLAQRQRLDNGKPISETRALVASAAGTFQF 115 Query: 265 FAAACETLEETITPMRGDNLTMSVYEAMGVVAAITPWNSPIASEAQKMAPALAAGNAVVV 324 FAAACETLEETITP RGD LTMSVYE MGVVAAITPWNSPIASEAQKMAPALAAGNAVVV Sbjct: 116 FAAACETLEETITPQRGDCLTMSVYEPMGVVAAITPWNSPIASEAQKMAPALAAGNAVVV 175 Query: 325 KPAEVTPLMALELARICEEAGVPKGLISVLPGKGSVIGDAITLHPLVKRVSFTGGTTTGK 384 KPAEVTPLMALELARICEEAGVPKGL+SVLPGKGSVIGDAIT HPLV+RVSFTGGTTTGK Sbjct: 176 KPAEVTPLMALELARICEEAGVPKGLLSVLPGKGSVIGDAITKHPLVRRVSFTGGTTTGK 235 Query: 385 HIAHIAADKMMPVSLELGGKSP 406 HIAHIAADKMMPVSLELGGKSP Sbjct: 236 HIAHIAADKMMPVSLELGGKSP 257 Score = 349 bits (895), Expect = 7e-94, Method: Compositional matrix adjust. Identities = 163/203 (80%), Positives = 181/203 (89%) Query: 1 MVFDDADIDHAVAGVLYGIFSSSGESCIAGSRLFVARSIYDSFMERLAAGAAALRVGDPA 60 MVFDDAD+DHAV GVLYGIFSSSGESCIAGSRLFVARS Y++F++RLAAGAA LRVGDPA Sbjct: 259 MVFDDADLDHAVNGVLYGIFSSSGESCIAGSRLFVARSQYEAFIDRLAAGAAHLRVGDPA 318 Query: 61 DERTQMGPLITARHREGIESYVSIGVADGGRIRTGGTRLAGDQFARGYYYAPTIIEGVTN 120 DERTQMGPLIT RHR+ IESYV+ GV +GG++RTGG R GY+Y PTIIEG+ N Sbjct: 319 DERTQMGPLITDRHRDSIESYVAAGVEEGGQLRTGGLRPDVAGLPNGYFYTPTIIEGLDN 378 Query: 121 DQRICQEEIFGPVLAAMPFDNEEDLIAQANDSVYALAAGIWTRDYKKAWRFGRAVQAGNV 180 + RICQEEIFGPVL A+PFD+E+DLIAQANDSVYALAAGIWTRDYK+AWR RAVQAGNV Sbjct: 379 NARICQEEIFGPVLVAIPFDDEDDLIAQANDSVYALAAGIWTRDYKRAWRVARAVQAGNV 438 Query: 181 WINTYKQFSISTPFGGWRDSGLG 203 WINTYKQFSI+TPFGGWRDSGLG Sbjct: 439 WINTYKQFSIATPFGGWRDSGLG 461 >ref|YP_002007254.1| nad+ dependent betaine aldehyde dehydrogenase [Cupriavidus taiwanensis LMG 19424] emb|CAQ71193.1| NAD+ dependent betaine aldehyde dehydrogenase [Cupriavidus taiwanensis LMG 19424] Length = 492 Score = 370 bits (951), Expect = e-100, Method: Compositional matrix adjust. Identities = 184/202 (91%), Positives = 190/202 (94%) Query: 205 FRTSGWAQKKPHERAIVLYRVAQLIRERGEALAQRQRLDNGKPITETRNLVGSAAATFQF 264 F TSGWAQ+KPHERA VLYRVA+LIR + E LAQRQRLDNGKPI+ETR LV SAA TFQF Sbjct: 56 FLTSGWAQRKPHERAAVLYRVAELIRAQAEPLAQRQRLDNGKPISETRALVASAAGTFQF 115 Query: 265 FAAACETLEETITPMRGDNLTMSVYEAMGVVAAITPWNSPIASEAQKMAPALAAGNAVVV 324 FAAACETLEETITP RGD LTMSVYE MGVVAAITPWNSPIASEAQKMAPALAAGNAVVV Sbjct: 116 FAAACETLEETITPQRGDCLTMSVYEPMGVVAAITPWNSPIASEAQKMAPALAAGNAVVV 175 Query: 325 KPAEVTPLMALELARICEEAGVPKGLISVLPGKGSVIGDAITLHPLVKRVSFTGGTTTGK 384 KPAEVTPLMALELARICEEAGVP+GLISVLPGKGSVIGDAIT HPLV+RVSFTGGTTTGK Sbjct: 176 KPAEVTPLMALELARICEEAGVPRGLISVLPGKGSVIGDAITKHPLVRRVSFTGGTTTGK 235 Query: 385 HIAHIAADKMMPVSLELGGKSP 406 HIAHIAADKMMPVSLELGGKSP Sbjct: 236 HIAHIAADKMMPVSLELGGKSP 257 Score = 345 bits (885), Expect = 9e-93, Method: Compositional matrix adjust. Identities = 161/203 (79%), Positives = 178/203 (87%) Query: 1 MVFDDADIDHAVAGVLYGIFSSSGESCIAGSRLFVARSIYDSFMERLAAGAAALRVGDPA 60 MVFDDAD+DHAV GVLYGIFSSSGESCIAGSRLFVARS Y++F++RLA GAA LRVGDPA Sbjct: 259 MVFDDADLDHAVNGVLYGIFSSSGESCIAGSRLFVARSQYEAFIDRLAHGAAQLRVGDPA 318 Query: 61 DERTQMGPLITARHREGIESYVSIGVADGGRIRTGGTRLAGDQFARGYYYAPTIIEGVTN 120 DERTQMGPLIT RHR+ IESYV+ GV +GG++RTGG R GY+Y PTIIEG+ N Sbjct: 319 DERTQMGPLITDRHRDSIESYVAAGVDEGGQLRTGGVRPDVAGLPNGYFYTPTIIEGLDN 378 Query: 121 DQRICQEEIFGPVLAAMPFDNEEDLIAQANDSVYALAAGIWTRDYKKAWRFGRAVQAGNV 180 RICQEEIFGPVL A+PFD+E+DL+ QANDSVYALAAGIWTRDYK+AWR RAVQAGNV Sbjct: 379 HARICQEEIFGPVLVAIPFDDEDDLVEQANDSVYALAAGIWTRDYKRAWRVARAVQAGNV 438 Query: 181 WINTYKQFSISTPFGGWRDSGLG 203 WINTYKQFSISTPFGGWRDSGLG Sbjct: 439 WINTYKQFSISTPFGGWRDSGLG 461 >ref|ZP_07674483.1| aldehyde dehydrogenase (NAD) family protein [Ralstonia sp. 5_7_47FAA] gb|EFP67163.1| aldehyde dehydrogenase (NAD) family protein [Ralstonia sp. 5_7_47FAA] Length = 500 Score = 366 bits (940), Expect = 4e-99, Method: Compositional matrix adjust. Identities = 180/202 (89%), Positives = 189/202 (93%) Query: 205 FRTSGWAQKKPHERAIVLYRVAQLIRERGEALAQRQRLDNGKPITETRNLVGSAAATFQF 264 F +SGWAQ+KPHERA VLYRVA+LIR R EALAQRQRLDNGKPI ETR LV SAAATFQF Sbjct: 63 FLSSGWAQRKPHERAAVLYRVAELIRSRSEALAQRQRLDNGKPINETRALVASAAATFQF 122 Query: 265 FAAACETLEETITPMRGDNLTMSVYEAMGVVAAITPWNSPIASEAQKMAPALAAGNAVVV 324 F AACETLEE++TPMRGD LTMSV+E MGVVAAITPWNSPIASEAQKMAPALAAGNAVVV Sbjct: 123 FGAACETLEESLTPMRGDCLTMSVHEPMGVVAAITPWNSPIASEAQKMAPALAAGNAVVV 182 Query: 325 KPAEVTPLMALELARICEEAGVPKGLISVLPGKGSVIGDAITLHPLVKRVSFTGGTTTGK 384 KPAEVTPLMALELA ICEEAGVPKG+ISVLPGKGSVIGDAIT HPLV+RVSFTGGT TG+ Sbjct: 183 KPAEVTPLMALELAAICEEAGVPKGMISVLPGKGSVIGDAITKHPLVRRVSFTGGTNTGR 242 Query: 385 HIAHIAADKMMPVSLELGGKSP 406 HIAHIAADKMMPVSLELGGKSP Sbjct: 243 HIAHIAADKMMPVSLELGGKSP 264 Score = 334 bits (857), Expect = 2e-89, Method: Compositional matrix adjust. Identities = 163/203 (80%), Positives = 180/203 (88%) Query: 1 MVFDDADIDHAVAGVLYGIFSSSGESCIAGSRLFVARSIYDSFMERLAAGAAALRVGDPA 60 MVF+DAD+DHAV GVLYGIFSSSGESCIAGSRLFVARS+Y+ FM+RLAA AA LRVG+PA Sbjct: 266 MVFEDADLDHAVNGVLYGIFSSSGESCIAGSRLFVARSLYEPFMDRLAAAAARLRVGNPA 325 Query: 61 DERTQMGPLITARHREGIESYVSIGVADGGRIRTGGTRLAGDQFARGYYYAPTIIEGVTN 120 DE TQMGPLIT RHRE +ESYV++GV +GG +RTGG R A GY+Y PTIIEG+TN Sbjct: 326 DESTQMGPLITDRHRETVESYVAMGVGEGGHLRTGGLRPAIAGCESGYFYTPTIIEGLTN 385 Query: 121 DQRICQEEIFGPVLAAMPFDNEEDLIAQANDSVYALAAGIWTRDYKKAWRFGRAVQAGNV 180 RICQEEIFGPVL AMPFD+E++LI QANDSVYALAAGIWTRDYK+AWR GRAVQAGNV Sbjct: 386 SARICQEEIFGPVLVAMPFDDEDELIEQANDSVYALAAGIWTRDYKRAWRIGRAVQAGNV 445 Query: 181 WINTYKQFSISTPFGGWRDSGLG 203 WINTYKQFSISTPFGGWRDSGLG Sbjct: 446 WINTYKQFSISTPFGGWRDSGLG 468 >ref|YP_001893019.1| Aldehyde Dehydrogenase [Ralstonia pickettii 12J] ref|YP_002984545.1| aldehyde dehydrogenase [Ralstonia pickettii 12D] gb|ACD29592.1| Aldehyde Dehydrogenase [Ralstonia pickettii 12J] gb|ACS65873.1| Aldehyde Dehydrogenase [Ralstonia pickettii 12D] Length = 500 Score = 366 bits (939), Expect = 6e-99, Method: Compositional matrix adjust. Identities = 179/202 (88%), Positives = 189/202 (93%) Query: 205 FRTSGWAQKKPHERAIVLYRVAQLIRERGEALAQRQRLDNGKPITETRNLVGSAAATFQF 264 F +SGWAQ+KPHERA VLYR+A+LIR R EALAQRQRLDNGKPI ETR LV SAAATFQF Sbjct: 63 FLSSGWAQRKPHERAAVLYRIAELIRSRSEALAQRQRLDNGKPINETRALVASAAATFQF 122 Query: 265 FAAACETLEETITPMRGDNLTMSVYEAMGVVAAITPWNSPIASEAQKMAPALAAGNAVVV 324 F AACETLEE++TPMRGD LTMSV+E MGVVAAITPWNSPIASEAQKMAPALAAGNAVVV Sbjct: 123 FGAACETLEESLTPMRGDCLTMSVHEPMGVVAAITPWNSPIASEAQKMAPALAAGNAVVV 182 Query: 325 KPAEVTPLMALELARICEEAGVPKGLISVLPGKGSVIGDAITLHPLVKRVSFTGGTTTGK 384 KPAEVTPLMALELA ICEEAGVPKG+ISVLPGKGSVIGDAIT HPLV+RVSFTGGT TG+ Sbjct: 183 KPAEVTPLMALELAAICEEAGVPKGMISVLPGKGSVIGDAITKHPLVRRVSFTGGTNTGR 242 Query: 385 HIAHIAADKMMPVSLELGGKSP 406 HIAHIAADKMMPVSLELGGKSP Sbjct: 243 HIAHIAADKMMPVSLELGGKSP 264 Score = 335 bits (858), Expect = 1e-89, Method: Compositional matrix adjust. Identities = 164/203 (80%), Positives = 180/203 (88%) Query: 1 MVFDDADIDHAVAGVLYGIFSSSGESCIAGSRLFVARSIYDSFMERLAAGAAALRVGDPA 60 MVF+DAD+DHAV GVLYGIFSSSGESCIAGSRLFVARS+Y+ FM+RLAA AA LRVG+PA Sbjct: 266 MVFEDADLDHAVNGVLYGIFSSSGESCIAGSRLFVARSLYEPFMDRLAAAAARLRVGNPA 325 Query: 61 DERTQMGPLITARHREGIESYVSIGVADGGRIRTGGTRLAGDQFARGYYYAPTIIEGVTN 120 DE TQMGPLIT RHRE IESYV++GV +GG +RTGG R A GY+Y PTIIEG+TN Sbjct: 326 DESTQMGPLITDRHRETIESYVAMGVGEGGHLRTGGLRPAIVGCESGYFYTPTIIEGLTN 385 Query: 121 DQRICQEEIFGPVLAAMPFDNEEDLIAQANDSVYALAAGIWTRDYKKAWRFGRAVQAGNV 180 RICQEEIFGPVL AMPFD+E++LI QANDSVYALAAGIWTRDYK+AWR GRAVQAGNV Sbjct: 386 SARICQEEIFGPVLVAMPFDDEDELIEQANDSVYALAAGIWTRDYKRAWRIGRAVQAGNV 445 Query: 181 WINTYKQFSISTPFGGWRDSGLG 203 WINTYKQFSISTPFGGWRDSGLG Sbjct: 446 WINTYKQFSISTPFGGWRDSGLG 468