BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0011.0031.p (327 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003775052.1| dehydrogenase oxidoreductase [Herbaspirillum... 580 e-163 ref|YP_004753703.1| 2-ketoaldonate reductase [Collimonas fungivo... 517 e-144 ref|YP_001099124.1| putative glyoxylate reductase (glycolate red... 511 e-143 ref|YP_001352411.1| 2-hydroxyacid dehydrogenase [Janthinobacteri... 505 e-141 ref|YP_004154268.1| D-isomer specific 2-hydroxyacid dehydrogenas... 442 e-122 >ref|YP_003775052.1| dehydrogenase oxidoreductase [Herbaspirillum seropedicae SmR1] emb|CAM32608.1| Dehydrogenase oxidoreductase protein [Herbaspirillum seropedicae] gb|ADJ63144.1| dehydrogenase oxidoreductase protein [Herbaspirillum seropedicae SmR1] Length = 326 Score = 580 bits (1495), Expect = e-163, Method: Compositional matrix adjust. Identities = 278/323 (86%), Positives = 303/323 (93%) Query: 1 MKPKIFVARAVFPEVLERLAQHFDVESNQEDRIFSADELIAKVQGKAGLFSTPSEPVSAA 60 MKPKIFVARAVFPEVL RL QHF+VESNQ+DRI+SA EL AK QGK GLF+TPSEPV+AA Sbjct: 1 MKPKIFVARAVFPEVLARLEQHFEVESNQDDRIYSAAELQAKAQGKDGLFTTPSEPVTAA 60 Query: 61 LFAANPQLKAVCNMAVGYNNIDIAAATKAGVQATNTPDVLNETTADFGWALLMATARRVT 120 LFAANPQLKAVCNMAVGYNNID+AAAT+AGV ATNTPDVLNETTADFGWAL+MA ARR+T Sbjct: 61 LFAANPQLKAVCNMAVGYNNIDVAAATQAGVMATNTPDVLNETTADFGWALMMAAARRIT 120 Query: 121 ESEHWLRAGHWKKWSYDSFTGPDVHGATLGIIGMGRIGQAIARRSLGFDMEVIYHNRSQL 180 ESEH+LRAG WKKWSYDSF GPD+HGATLGIIGMGRIGQAIARRSLGFDM+V+YHNRS+L Sbjct: 121 ESEHFLRAGKWKKWSYDSFVGPDIHGATLGIIGMGRIGQAIARRSLGFDMQVLYHNRSRL 180 Query: 181 SPELEARANNAKYVGKEELLRTADHVILVLPYSKESHHTIKAADLALMKPQATLINLARG 240 +PELEARAN+A+YV KEELLR ADHVILVLPYSK++HHTI AA+LALMKP ATL N+ARG Sbjct: 181 APELEARANHARYVSKEELLRQADHVILVLPYSKDTHHTIAAAELALMKPTATLTNIARG 240 Query: 241 GIVDDAALIAALRDRKIAAAGLDVFENEPAFHPDFLGLSNVVLTPHIASASTPTRLAMAN 300 GIVDDAALIAALR+ +IAAAG+DVFENEPAF P+FL LSNVVLTPHIASASTPTRLAMAN Sbjct: 241 GIVDDAALIAALREGRIAAAGVDVFENEPAFKPEFLDLSNVVLTPHIASASTPTRLAMAN 300 Query: 301 CAADNLIAALSGQTPPNLLNRDV 323 CAADNLIAALSGQ PPNLLN DV Sbjct: 301 CAADNLIAALSGQRPPNLLNPDV 323 >ref|YP_004753703.1| 2-ketoaldonate reductase [Collimonas fungivorans Ter331] gb|AEK62880.1| 2-ketoaldonate reductase, broad specificity [Collimonas fungivorans Ter331] Length = 334 Score = 517 bits (1331), Expect = e-144, Method: Compositional matrix adjust. Identities = 261/327 (79%), Positives = 285/327 (87%), Gaps = 4/327 (1%) Query: 1 MKPKIFVARAVFPEVLERLAQHFDVESNQEDRIFSADELIAKVQGKAGLFSTPSEPVSAA 60 MKPKI +ARAVFPEV+ L QHF+VESNQ+DRIFSA EL K+ K G+ +T SE +SA Sbjct: 1 MKPKILMARAVFPEVIASLQQHFEVESNQDDRIFSAAELTQKLSDKDGVIATASERISAE 60 Query: 61 LFAANPQLKAVCNMAVGYNNIDIAAATKAGVQATNTPDVLNETTADFGWALLMATARRVT 120 L A P+LKAVCN AVGYNNID+AAATKAGV TNTPDVLNETTADFGWALLMATARRVT Sbjct: 61 LLQACPRLKAVCNQAVGYNNIDVAAATKAGVMVTNTPDVLNETTADFGWALLMATARRVT 120 Query: 121 ESEHWLRAGHWKKWSYDSFTGPDVHGATLGIIGMGRIGQAIARRSLGFDMEVIYHNRSQL 180 ESEHWLRAGHWK+W YDSF G DVHGATLGIIGMGRIGQAIARRSLGFDM+V+YHNRS+L Sbjct: 121 ESEHWLRAGHWKQWRYDSFLGADVHGATLGIIGMGRIGQAIARRSLGFDMQVLYHNRSRL 180 Query: 181 SPELEARANNAKYVGKEELLRTADHVILVLPYSKESHHTIKAADLALMKPQATLINLARG 240 +PELEARANNA+Y GKEELL ADHVILVLPYSKESHHTI AA+LALMKP ATL+NLARG Sbjct: 181 APELEARANNARYAGKEELLAAADHVILVLPYSKESHHTIGAAELALMKPGATLVNLARG 240 Query: 241 GIVDDAALIAALRDRKIAAAGLDVFENEPAFHPDFLGLSNVVLTPHIASASTPTRLAMAN 300 GIVDD ALIAALRD++IAAAGLDVFENEPA HPDFL LSNVVLTPHIASAS PTR AMA+ Sbjct: 241 GIVDDLALIAALRDKRIAAAGLDVFENEPALHPDFLELSNVVLTPHIASASEPTRRAMAD 300 Query: 301 CAADNLIAAL----SGQTPPNLLNRDV 323 CAA NL+AAL + PPNLLN +V Sbjct: 301 CAAANLLAALLPTAERKWPPNLLNPEV 327 >ref|YP_001099124.1| putative glyoxylate reductase (glycolate reductase) [Herminiimonas arsenicoxydans] emb|CAL60997.1| putative glyoxylate reductase (Glycolate reductase) [Herminiimonas arsenicoxydans] Length = 327 Score = 511 bits (1316), Expect = e-143, Method: Compositional matrix adjust. Identities = 239/327 (73%), Positives = 279/327 (85%) Query: 1 MKPKIFVARAVFPEVLERLAQHFDVESNQEDRIFSADELIAKVQGKAGLFSTPSEPVSAA 60 MK KI VARA FP+V+ERL Q F+VESNQEDRIFS EL K+QGK G+ T SE +S Sbjct: 1 MKQKILVARATFPDVIERLQQQFEVESNQEDRIFSPAELHEKMQGKDGVIITSSEKLSGE 60 Query: 61 LFAANPQLKAVCNMAVGYNNIDIAAATKAGVQATNTPDVLNETTADFGWALLMATARRVT 120 + ANPQLKA+CN+AVGYNNID+AAATKAG+ TNTPDVLNETTAD+ W LLMA ARR + Sbjct: 61 VITANPQLKAICNVAVGYNNIDVAAATKAGIMVTNTPDVLNETTADYAWTLLMANARRTS 120 Query: 121 ESEHWLRAGHWKKWSYDSFTGPDVHGATLGIIGMGRIGQAIARRSLGFDMEVIYHNRSQL 180 ESEH+LRAG WK W +D F G DVHGATLGI+GMGRIGQAIARRS+GFDM+VIYHNRS+L Sbjct: 121 ESEHYLRAGKWKNWRFDQFLGADVHGATLGILGMGRIGQAIARRSMGFDMQVIYHNRSRL 180 Query: 181 SPELEARANNAKYVGKEELLRTADHVILVLPYSKESHHTIKAADLALMKPQATLINLARG 240 +P+ EA ANNA+YV KEELLRTADH+ILVLPYS+++HH I AA+LALMKP ATL+N+ARG Sbjct: 181 TPDQEAHANNARYVSKEELLRTADHLILVLPYSEQTHHIIGAAELALMKPTATLVNIARG 240 Query: 241 GIVDDAALIAALRDRKIAAAGLDVFENEPAFHPDFLGLSNVVLTPHIASASTPTRLAMAN 300 GIVDD ALIAALR+ +IA+AGLDV+ENEPA HPDFL LSNVVLTPHI SAS TR AM++ Sbjct: 241 GIVDDVALIAALREHRIASAGLDVYENEPALHPDFLTLSNVVLTPHIGSASEKTRRAMSD 300 Query: 301 CAADNLIAALSGQTPPNLLNRDVQPKR 327 CA+ N++AALSGQ PPNLLN +VQ K+ Sbjct: 301 CASLNMVAALSGQRPPNLLNPEVQAKK 327 >ref|YP_001352411.1| 2-hydroxyacid dehydrogenase [Janthinobacterium sp. Marseille] gb|ABR88877.1| 2-hydroxyacid dehydrogenase [Janthinobacterium sp. Marseille] Length = 327 Score = 505 bits (1301), Expect = e-141, Method: Compositional matrix adjust. Identities = 239/327 (73%), Positives = 276/327 (84%) Query: 1 MKPKIFVARAVFPEVLERLAQHFDVESNQEDRIFSADELIAKVQGKAGLFSTPSEPVSAA 60 MK K+ VARA FP+V+ERL Q F+VESNQED+IFS EL+ K+QGK + T SE +SA Sbjct: 1 MKAKVLVARATFPDVIERLQQQFEVESNQEDKIFSPAELLQKMQGKDAVVVTASEKMSAD 60 Query: 61 LFAANPQLKAVCNMAVGYNNIDIAAATKAGVQATNTPDVLNETTADFGWALLMATARRVT 120 + AANPQLKA+CN+AVGYNNID+AAAT AGV TNTPDVLNETTAD+ W LLMA ARRV Sbjct: 61 VIAANPQLKAICNVAVGYNNIDVAAATAAGVMVTNTPDVLNETTADYAWTLLMANARRVC 120 Query: 121 ESEHWLRAGHWKKWSYDSFTGPDVHGATLGIIGMGRIGQAIARRSLGFDMEVIYHNRSQL 180 ESEHWLRAG+WK W +DSF G D+HGATLGI+GMGRIGQAIARRS GFDM VIYHNRS+ Sbjct: 121 ESEHWLRAGNWKHWRFDSFLGADIHGATLGILGMGRIGQAIARRSTGFDMNVIYHNRSRA 180 Query: 181 SPELEARANNAKYVGKEELLRTADHVILVLPYSKESHHTIKAADLALMKPQATLINLARG 240 +PE EA ANNA+YV KEELLR+ADH+ILVLPYS ++HH I AA+LALMKP ATL+N+ARG Sbjct: 181 TPEQEAYANNARYVSKEELLRSADHLILVLPYSPQTHHIIGAAELALMKPTATLVNIARG 240 Query: 241 GIVDDAALIAALRDRKIAAAGLDVFENEPAFHPDFLGLSNVVLTPHIASASTPTRLAMAN 300 GIVDD ALIAALR+ +IA+AGLDVFENEPA HPDFL LSNVVLTPHI S S TR AMA+ Sbjct: 241 GIVDDVALIAALRENRIASAGLDVFENEPALHPDFLTLSNVVLTPHIGSGSEKTRRAMAD 300 Query: 301 CAADNLIAALSGQTPPNLLNRDVQPKR 327 CA+ NL AA+SGQ PPNLLN +V+ K+ Sbjct: 301 CASANLAAAMSGQQPPNLLNPEVKAKK 327 >ref|YP_004154268.1| D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein [Variovorax paradoxus EPS] gb|ADU36157.1| D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein [Variovorax paradoxus EPS] Length = 328 Score = 442 bits (1136), Expect = e-122, Method: Compositional matrix adjust. Identities = 217/315 (68%), Positives = 251/315 (79%), Gaps = 2/315 (0%) Query: 2 KPKIFVARAVFPEVLERLAQHFDVESNQEDRIFSADELIAKVQGKAGLFSTPSEPVSAAL 61 KPKI VARA+FPE +ERL+QHF+VESNQ D +S ++LIAK++GK G F+T SE + AA+ Sbjct: 3 KPKILVARAIFPETIERLSQHFEVESNQSDESWSKEQLIAKLKGKQGAFTTGSERIDAAV 62 Query: 62 FAANPQLKAVCNMAVGYNNIDIAAATKAGVQATNTPDVLNETTADFGWALLMATARRVTE 121 ANP LK NMAVGYNN D+ A GV TN PDVL ETTADFG+ALLMATARR+TE Sbjct: 63 LDANPDLKICANMAVGYNNFDVDAMAAHGVLGTNAPDVLTETTADFGFALLMATARRITE 122 Query: 122 SEHWLRAGHWKKWSYDSFTGPDVHGATLGIIGMGRIGQAIARRSL-GFDMEVIYHNRSQL 180 SEH+LRAG W+KWSYD F G D+HGATLGIIGMGRIGQ IA+R GF M+VIYHNRS+L Sbjct: 123 SEHFLRAGKWEKWSYDMFAGSDIHGATLGIIGMGRIGQGIAKRGAHGFGMKVIYHNRSRL 182 Query: 181 SPELEARANNAKYVGKEELLRTADHVILVLPYSKESHHTIKAADLALMKPQATLINLARG 240 LEA A YV KEELL+TADHV+LV+PYS SHHTI A +LALMKP ATL+N+ARG Sbjct: 183 DATLEADC-KASYVSKEELLKTADHVVLVVPYSPASHHTIGAGELALMKPTATLVNIARG 241 Query: 241 GIVDDAALIAALRDRKIAAAGLDVFENEPAFHPDFLGLSNVVLTPHIASASTPTRLAMAN 300 GIVDDAAL ALR+++IAAAGLDVFE EP HPD L + NVVLTPHIASA+ PTR AMA+ Sbjct: 242 GIVDDAALAVALREKRIAAAGLDVFEGEPKVHPDLLTVPNVVLTPHIASATVPTRRAMAD 301 Query: 301 CAADNLIAALSGQTP 315 AADNLIA SG+ P Sbjct: 302 LAADNLIAYFSGKGP 316