BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0010.0014.p (232 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003776973.1| bifunctional GTP cyclohydrolase II/3,4-dihyd... 405 e-111 ref|YP_001354030.1| bifunctional 3,4-dihydroxy-2-butanone 4-phos... 377 e-102 ref|YP_001099343.1| bifunctional 3,4-dihydroxy-2-butanone 4-phos... 376 e-102 ref|YP_004754082.1| 3,4-dihydroxy-2-butanone 4-phosphate synthas... 365 4e-99 ref|YP_004686548.1| 3,4-dihydroxy-2-butanone 4-phosphate synthas... 332 2e-89 >ref|YP_003776973.1| bifunctional GTP cyclohydrolase II/3,4-dihydroxy-2-butanone-4-phosphate synthase [Herbaspirillum seropedicae SmR1] gb|ADJ65065.1| bifunctional enzyme: GTP cyclohydrolase II/3,4-dihydroxy-2-butanone-4-phosphate synthase (DHBP synthase) protein [Herbaspirillum seropedicae SmR1] Length = 373 Score = 405 bits (1042), Expect = e-111, Method: Compositional matrix adjust. Identities = 195/235 (82%), Positives = 214/235 (91%), Gaps = 3/235 (1%) Query: 1 MRAGHTEAGCDLTQMAGLTPAAVICEILKDDGTMARLPDLLEFAEEHKLKIGTIADLIHY 60 MRAGHTEAGCDLT MAGLTPA+VICEILK+DGTMARLPDLLEFAE+HKLKIGTIADLIHY Sbjct: 139 MRAGHTEAGCDLTAMAGLTPASVICEILKEDGTMARLPDLLEFAEKHKLKIGTIADLIHY 198 Query: 61 RSQHESIIERVAEREMHTVHGSFKAIAYRDTPSGGAHLALVHGDIRPGEETLVRVHQPVS 120 RS++ESIIERVAEREM T HG+FKAIAYRDTPSGGAHLALV GDI+PG ETLVRVHQPVS Sbjct: 199 RSRNESIIERVAEREMQTAHGAFKAIAYRDTPSGGAHLALVRGDIQPGRETLVRVHQPVS 258 Query: 121 ILDLLETKATTHSWNMASAMAAIKAAPSGVVVLLNCEESADQMFAQFTALNNV---QAAK 177 ILDLL+ TTHSWN+A+AM A++ A SGV+VLLNCEESA QMF QF ALN V +AAK Sbjct: 259 ILDLLDAGVTTHSWNLAAAMKAVQEAESGVIVLLNCEESAQQMFDQFGALNKVGTPEAAK 318 Query: 178 PARADRLDLRTYGIGAQILKDLGVCKMQLLASPRKMPSMTGFNLEVTGYRAKPDA 232 P+RADR+DLRTYGIGAQILKDLGVCKM+LLASPRKMPSMTGF LEVTGY+A+ A Sbjct: 319 PSRADRMDLRTYGIGAQILKDLGVCKMKLLASPRKMPSMTGFQLEVTGYQAREGA 373 >ref|YP_001354030.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II-like protein [Janthinobacterium sp. Marseille] gb|ABR88970.1| bifunctional riboflavin biosynthesis protein [Janthinobacterium sp. Marseille] Length = 370 Score = 377 bits (967), Expect = e-102, Method: Compositional matrix adjust. Identities = 177/231 (76%), Positives = 201/231 (87%) Query: 1 MRAGHTEAGCDLTQMAGLTPAAVICEILKDDGTMARLPDLLEFAEEHKLKIGTIADLIHY 60 MRAGHTEAGCD ++AGLTPAAVICEI+KDDGTMARLPDL+EFA+EH LKIGTIADLIHY Sbjct: 139 MRAGHTEAGCDFAELAGLTPAAVICEIMKDDGTMARLPDLIEFAKEHGLKIGTIADLIHY 198 Query: 61 RSQHESIIERVAEREMHTVHGSFKAIAYRDTPSGGAHLALVHGDIRPGEETLVRVHQPVS 120 RSQHE+I++RV ER M TV+GSFK I YRD PSGGAHLALVHGDI +ETLVRVHQPVS Sbjct: 199 RSQHETIVDRVGERVMETVYGSFKTIVYRDKPSGGAHLALVHGDISADQETLVRVHQPVS 258 Query: 121 ILDLLETKATTHSWNMASAMAAIKAAPSGVVVLLNCEESADQMFAQFTALNNVQAAKPAR 180 +LD LETKATTHSWN+ASAMAAIK + GV+VLLNCEESAD+ F+QF ALNN ++ R Sbjct: 259 VLDWLETKATTHSWNLASAMAAIKQSERGVMVLLNCEESADEFFSQFEALNNPESRPQQR 318 Query: 181 ADRLDLRTYGIGAQILKDLGVCKMQLLASPRKMPSMTGFNLEVTGYRAKPD 231 A +DLRTYGIGAQILKDL V KM+LLA+ RKMPSM GF+LEVTGY+A+ D Sbjct: 319 AAHMDLRTYGIGAQILKDLSVGKMKLLANQRKMPSMAGFDLEVTGYQARTD 369 >ref|YP_001099343.1| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II-like protein [Herminiimonas arsenicoxydans] emb|CAL61216.1| Riboflavin biosynthesis protein ribAB [Includes: GTP cyclohydrolase-2 (GTP cyclohydrolase II); 3, 4-dihydroxy-2-butanone 4-phosphate synthase (DHBP synthase)] [Herminiimonas arsenicoxydans] Length = 370 Score = 376 bits (965), Expect = e-102, Method: Compositional matrix adjust. Identities = 176/232 (75%), Positives = 202/232 (87%) Query: 1 MRAGHTEAGCDLTQMAGLTPAAVICEILKDDGTMARLPDLLEFAEEHKLKIGTIADLIHY 60 MRAGHTEAGCD ++AGL PAAVICEI+KDDGTMARLPDL+EFA+EH LKIGTIADLIHY Sbjct: 139 MRAGHTEAGCDFAELAGLVPAAVICEIMKDDGTMARLPDLIEFAKEHDLKIGTIADLIHY 198 Query: 61 RSQHESIIERVAEREMHTVHGSFKAIAYRDTPSGGAHLALVHGDIRPGEETLVRVHQPVS 120 RSQHESI++RV ER M TV+G+F A+ YRD PSGGAHLALVHGDI P +ETLVRVHQPVS Sbjct: 199 RSQHESIVDRVDERTMETVYGTFHAVLYRDKPSGGAHLALVHGDIAPDQETLVRVHQPVS 258 Query: 121 ILDLLETKATTHSWNMASAMAAIKAAPSGVVVLLNCEESADQMFAQFTALNNVQAAKPAR 180 ILDLL+T+ATTHSWNMASA+AAI+ GV+VLLNCEESA+++F+QF AL + R Sbjct: 259 ILDLLDTRATTHSWNMASAIAAIRQVERGVMVLLNCEESAEELFSQFAALTHPDTRPQQR 318 Query: 181 ADRLDLRTYGIGAQILKDLGVCKMQLLASPRKMPSMTGFNLEVTGYRAKPDA 232 A R+DLR YGIGAQILKDL V KM+LLA+PRKMPSMTGFNLEVTGYRA P++ Sbjct: 319 AARMDLRNYGIGAQILKDLSVGKMKLLANPRKMPSMTGFNLEVTGYRATPES 370 >ref|YP_004754082.1| 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II [Collimonas fungivorans Ter331] gb|AEK63259.1| 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II [Collimonas fungivorans Ter331] Length = 370 Score = 365 bits (936), Expect = 4e-99, Method: Compositional matrix adjust. Identities = 182/232 (78%), Positives = 203/232 (87%) Query: 1 MRAGHTEAGCDLTQMAGLTPAAVICEILKDDGTMARLPDLLEFAEEHKLKIGTIADLIHY 60 MRAGHTEAGCDLT+MAGLTPAAVICEILK+DGTMARLPDLLEF++EH LK+GTIADLIHY Sbjct: 139 MRAGHTEAGCDLTEMAGLTPAAVICEILKEDGTMARLPDLLEFSKEHGLKVGTIADLIHY 198 Query: 61 RSQHESIIERVAEREMHTVHGSFKAIAYRDTPSGGAHLALVHGDIRPGEETLVRVHQPVS 120 R QHESI+ER+AER HT G+FK IAYRDTPSGGAHLAL+HG P ETLVRVHQPVS Sbjct: 199 RGQHESIVERLAERTTHTAQGTFKTIAYRDTPSGGAHLALLHGTPAPDVETLVRVHQPVS 258 Query: 121 ILDLLETKATTHSWNMASAMAAIKAAPSGVVVLLNCEESADQMFAQFTALNNVQAAKPAR 180 ILDLLET+AT HSWNMASA+AAI A+P GVVVLLNCEESADQ+FA+F AL + Sbjct: 259 ILDLLETEATNHSWNMASALAAISASPCGVVVLLNCEESADQIFAKFAALEAACSGVKPP 318 Query: 181 ADRLDLRTYGIGAQILKDLGVCKMQLLASPRKMPSMTGFNLEVTGYRAKPDA 232 R+DLRTYGIGAQILKDLGV KM+LLASPRKMPSMTG++LEVTGY+ KP+A Sbjct: 319 PPRVDLRTYGIGAQILKDLGVGKMKLLASPRKMPSMTGYDLEVTGYQNKPNA 370 >ref|YP_004686548.1| 3,4-dihydroxy-2-butanone 4-phosphate synthase RibB [Cupriavidus necator N-1] gb|AEI78067.1| 3,4-dihydroxy-2-butanone 4-phosphate synthase RibB [Cupriavidus necator N-1] Length = 369 Score = 332 bits (852), Expect = 2e-89, Method: Compositional matrix adjust. Identities = 159/227 (70%), Positives = 195/227 (85%), Gaps = 3/227 (1%) Query: 1 MRAGHTEAGCDLTQMAGLTPAAVICEILKDDGTMARLPDLLEFAEEHKLKIGTIADLIHY 60 +RAGHTEAGCDL +AGLTPAAVICEI+KDDGTMARLPDL+EFA+EH LKIGTIADLIHY Sbjct: 139 IRAGHTEAGCDLGALAGLTPAAVICEIMKDDGTMARLPDLIEFAQEHDLKIGTIADLIHY 198 Query: 61 RSQHESIIERVAEREMHTVHGSFKAIAYRDTPSGGAHLALVHGDIRPGEETLVRVHQPVS 120 RS+ ESIIERV ER+M T +G+F++IAYRD P+G AHLALV G P +ETLVRVH+P S Sbjct: 199 RSRTESIIERVGERDMQTPYGTFRSIAYRDKPTGQAHLALVKGSPAPDQETLVRVHEPFS 258 Query: 121 ILDLLETKATTHSWNMASAMAAIKAAPSGVVVLLNCEESADQMFAQFTALNNVQAAKPAR 180 +LDLLE K TTHSW++ +A+ AI A +GVVVLLNC +SADQ+F QF+AL+ Q ++P R Sbjct: 259 VLDLLEVKRTTHSWSIPAALEAIAGADNGVVVLLNCGDSADQLFTQFSALDAPQ-SRPRR 317 Query: 181 ADRLDLRTYGIGAQILKDLGVCKMQLLASPRKMPSMTGFNLEVTGYR 227 + DLRTYG+GAQILKD+GV +M++LASP++MPSMTGF+LEVTGY+ Sbjct: 318 --KPDLRTYGMGAQILKDVGVGRMRVLASPQRMPSMTGFDLEVTGYQ 362