BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0010.0009.p (460 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_995151.1| heavy metal sensor signal transduction histidin... 786 0.0 ref|YP_003775892.1| two component heavy metal sensor histidine k... 613 e-173 ref|YP_004751898.1| heavy metal sensor histidine kinase [Collimo... 586 e-165 gb|EGP44711.1| heavy metal sensor signal transduction histidine ... 501 e-139 ref|YP_004156914.1| heavy metal sensor signal transduction histi... 475 e-132 >ref|YP_995151.1| heavy metal sensor signal transduction histidine kinase [Verminephrobacter eiseniae EF01-2] gb|ABM56133.1| heavy metal sensor signal transduction histidine kinase [Verminephrobacter eiseniae EF01-2] Length = 458 Score = 786 bits (2031), Expect = 0.0, Method: Compositional matrix adjust. Identities = 375/454 (82%), Positives = 411/454 (90%) Query: 1 MRHSIIARLVMMFAAAALVIFSLIGGVLYAVVKNELLRHERDGLVTTFNDIEYMVSRVGT 60 M++SIIARLV+MFAAAAL+IFSLIG VLYAVV NELL HER+ LVTTF DIEYMVSR GT Sbjct: 1 MKNSIIARLVIMFAAAALIIFSLIGSVLYAVVDNELLHHERNSLVTTFKDIEYMVSRAGT 60 Query: 61 VERWARVQTKLDTLTPADGKVRFWVFSDDPQFSYGKDLAELHDFDYDPNNIGRLRIKGKE 120 ERWA VQ KLDTLTPADGKVRFW+FSDDP+F YGKDLAELH+F PNN+GR+ IKGK+ Sbjct: 61 TERWAHVQVKLDTLTPADGKVRFWIFSDDPRFGYGKDLAELHEFANHPNNLGRMSIKGKK 120 Query: 121 FPMHTLTKVLPAYLDRPAIRLTIGVDTEPYFETLRTFVIAMIGLSLAGIFLVILFGYWIA 180 +P+HTLT++LPAYLDRPAIRLT+GVD YFETLRTFV AM GLSLAG+ LVIL GYWIA Sbjct: 121 YPLHTLTRILPAYLDRPAIRLTVGVDAASYFETLRTFVAAMTGLSLAGVLLVILCGYWIA 180 Query: 181 RAGLQPLKKMSDKAQTLSPQTLSERLTVSALPDELSDLAQAFNGALDRMENAYKQLEAFN 240 R GLQPLKKMSDKAQTLSP+TLSERLT+SALPDELSDLAQAFNGALDRMENAYKQLEAFN Sbjct: 181 RTGLQPLKKMSDKAQTLSPKTLSERLTLSALPDELSDLAQAFNGALDRMENAYKQLEAFN 240 Query: 241 ADVAHELRTPLANLIGETQVALSRERSAPEFEIVLQSNLEELDRLRSIINDMLFLARCDQ 300 ADVAHELRTPLANLIGETQVALSRERSAPEFE VLQSNLEE+DRLRSIINDMLFLARCDQ Sbjct: 241 ADVAHELRTPLANLIGETQVALSRERSAPEFESVLQSNLEEMDRLRSIINDMLFLARCDQ 300 Query: 301 GEAATSLVYTAIADEVQKTIEFFEFVLDEMQMSVEVVGDVDAKSMIETALFRRALTNLLQ 360 GEAAT LV+ IADEVQKT++FFEFVLDE M VE+ GD A ++IET+LFRRALTNLLQ Sbjct: 301 GEAATGLVHALIADEVQKTMDFFEFVLDETGMRVEISGDTHATALIETSLFRRALTNLLQ 360 Query: 361 NAIQHSPAGARITVSIDAQQQDVQVAVSNPGEPIEQRHLPRLFDRFYRVDSARRDFDGVH 420 NAIQHSPAGA I V+IDA+ VQ+AVSNPGEP+EQ HLPRLFDRFYRVD+ARRD +G+H Sbjct: 361 NAIQHSPAGACIEVAIDAKNHGVQIAVSNPGEPVEQGHLPRLFDRFYRVDTARRDINGIH 420 Query: 421 GHGLGLAIVKAIALMHGGTAFASSRGGKTTIGFT 454 GHGLGLAIVKAIALMHGG+ FA+S GG TTIGFT Sbjct: 421 GHGLGLAIVKAIALMHGGSVFAASTGGVTTIGFT 454 >ref|YP_003775892.1| two component heavy metal sensor histidine kinase [Herbaspirillum seropedicae SmR1] gb|ADJ63984.1| two component heavy metal sensor histidine kinase protein [Herbaspirillum seropedicae SmR1] Length = 467 Score = 613 bits (1580), Expect = e-173, Method: Compositional matrix adjust. Identities = 298/459 (64%), Positives = 365/459 (79%), Gaps = 4/459 (0%) Query: 1 MRHSIIARLVMMFAAAALVIFSLIGGVLYAVVKNELLRHERDGLVTTFNDIEYMVSRVGT 60 +R SI ARLV M AA+AL+IF+L G VLY V+K ELLRHERDGLVTT NDI Y + R G Sbjct: 8 LRQSITARLVWMSAASALLIFALTGMVLYTVLKGELLRHERDGLVTTLNDISYQIGRAGN 67 Query: 61 VERWARVQTKLDTLTPADGKVRFWVFSDDPQFSYGKDLAELHDFDY---DPNNIGRLRIK 117 ERW RVQ KL TL+ AD V FW+ S D +F+YG DL+ L + N++GRL + Sbjct: 68 TERWGRVQAKLATLSQADQHVSFWISSSDARFTYG-DLSRLAPQAIRADEGNSVGRLHLP 126 Query: 118 GKEFPMHTLTKVLPAYLDRPAIRLTIGVDTEPYFETLRTFVIAMIGLSLAGIFLVILFGY 177 G+ +P+H +T+ LPA+ +RPA+ +T+GVD EPYFE RTF++A SL GI L ++ Y Sbjct: 127 GRRYPLHIMTRTLPAFEERPAVDVTVGVDGEPYFEMRRTFLLATSVFSLLGIVLAVISSY 186 Query: 178 WIARAGLQPLKKMSDKAQTLSPQTLSERLTVSALPDELSDLAQAFNGALDRMENAYKQLE 237 WIARAGL PL++MSD+AQ+ SP+ LS R+ V A+P ELS LA AFNGALDR+E+AY QLE Sbjct: 187 WIARAGLAPLRQMSDRAQSFSPRKLSARMPVEAMPQELSVLALAFNGALDRIEDAYTQLE 246 Query: 238 AFNADVAHELRTPLANLIGETQVALSRERSAPEFEIVLQSNLEELDRLRSIINDMLFLAR 297 AFNADVAHELRTPLANLIGETQVAL+RERSA EF+ VLQSNLEELDR+RSI+NDMLFLAR Sbjct: 247 AFNADVAHELRTPLANLIGETQVALARERSAGEFKDVLQSNLEELDRIRSIVNDMLFLAR 306 Query: 298 CDQGEAATSLVYTAIADEVQKTIEFFEFVLDEMQMSVEVVGDVDAKSMIETALFRRALTN 357 DQGEAAT+ V +ADEVQKT++FFEFVLD+ M +EV GD +A +M+ETALF+RALTN Sbjct: 307 SDQGEAATARVPARVADEVQKTVDFFEFVLDDSGMRIEVAGDTEATAMMETALFKRALTN 366 Query: 358 LLQNAIQHSPAGARITVSIDAQQQDVQVAVSNPGEPIEQRHLPRLFDRFYRVDSARRDFD 417 L+QNAIQHSP GA + + I Q++ V+VAVSNPG+PI++ HLPRLFDRFYRVDSAR+D + Sbjct: 367 LIQNAIQHSPEGALLRIDIACQEETVRVAVSNPGKPIDEHHLPRLFDRFYRVDSARQDIN 426 Query: 418 GVHGHGLGLAIVKAIALMHGGTAFASSRGGKTTIGFTVG 456 G HGHGLGLAIVKA+A MHGG AFASS+ G +IGFT+ Sbjct: 427 GSHGHGLGLAIVKAVARMHGGRAFASSKEGVNSIGFTIA 465 >ref|YP_004751898.1| heavy metal sensor histidine kinase [Collimonas fungivorans Ter331] gb|AEK61075.1| Heavy metal sensor histidine kinase [Collimonas fungivorans Ter331] Length = 465 Score = 586 bits (1511), Expect = e-165, Method: Compositional matrix adjust. Identities = 293/462 (63%), Positives = 362/462 (78%), Gaps = 2/462 (0%) Query: 1 MRHSIIARLVMMFAAAALVIFSLIGGVLYAVVKNELLRHERDGLVTTFNDIEYMVSRVGT 60 M+ SI RLV MFA AAL+IFSLIG LY V++ EL RH++D L T F D YM+ G Sbjct: 1 MKRSITVRLVAMFALAALLIFSLIGSALYGVLQRELARHQQDELNTRFLDTRYMIGHNGD 60 Query: 61 VERWARVQTKLDTLTPADGKVRFWVFSDDPQFSYGKDLAELHDFDYDPNNIGRLRIKGKE 120 RW RVQTKL+TLTPADG +R+WV SDDP+F YGK LA++ D +PN +G + ++G+E Sbjct: 61 PARWPRVQTKLETLTPADGSIRYWVLSDDPRFQYGKGLADVEQLDRNPNGMGIMSLRGRE 120 Query: 121 FPMHTLTKVLPAYLDRPAIRLTIGVDTEPYFETLRTFVIAMIGLSLAGIFLVILFGYWIA 180 +P+HT+ + + +RPA+RL + VD PY TL F+IA++GLSL G+ LV+L GYWIA Sbjct: 121 YPLHTMIGTIEPFQERPAVRLIVAVDAAPYMHTLHAFMIALVGLSLLGVLLVMLLGYWIA 180 Query: 181 RAGLQPLKKMSDKAQTLSPQTLSERLTVSALPDELSDLAQAFNGALDRMENAYKQLEAFN 240 + GL+PLK++S AQ+L P+TLS+RL +S LP ELSDL AFNG L+RME AY QLEAFN Sbjct: 181 QVGLRPLKQLSSAAQSLGPKTLSQRLQISPLPGELSDLTIAFNGVLERMEGAYNQLEAFN 240 Query: 241 ADVAHELRTPLANLIGETQVALSRERSAPEFEIVLQSNLEELDRLRSIINDMLFLARCDQ 300 ADVAHELRTPLANLIGETQVALSR+R+AP+FE VLQSNLEEL+RLRSIINDMLFLAR DQ Sbjct: 241 ADVAHELRTPLANLIGETQVALSRQRTAPQFEEVLQSNLEELERLRSIINDMLFLARADQ 300 Query: 301 GEAATSLVYTAIADEVQKTIEFFEFVLDEMQMSVEVVGDVDAKSMIETALFRRALTNLLQ 360 GEAATSLV T+IA EV KT+EFFEF+LD+ +M+V+V GDV A++ IET+LF+RA++NLL Sbjct: 301 GEAATSLVRTSIAQEVGKTVEFFEFLLDDSKMTVKVAGDVSAEASIETSLFKRAMSNLLH 360 Query: 361 NAIQHSPAGARITVSIDAQQQDVQVAVSNPGEPIEQRHLPRLFDRFYRVDSARRDFD--G 418 NAIQHS GA I V+I + + +++AVSNPG+PI HLPRLFDRFYRVD+AR D D Sbjct: 361 NAIQHSSPGAAIAVTITQEPEAIRIAVSNPGKPISDNHLPRLFDRFYRVDAARNDKDQSQ 420 Query: 419 VHGHGLGLAIVKAIALMHGGTAFASSRGGKTTIGFTVGGKAA 460 +HGHGLGLAIVKAIA MHGG FA S G TTIGF++ A Sbjct: 421 LHGHGLGLAIVKAIAKMHGGGVFADSTDGTTTIGFSIPASHA 462 >gb|EGP44711.1| heavy metal sensor signal transduction histidine kinase [Achromobacter xylosoxidans AXX-A] Length = 460 Score = 501 bits (1289), Expect = e-139, Method: Compositional matrix adjust. Identities = 263/461 (57%), Positives = 336/461 (72%), Gaps = 2/461 (0%) Query: 1 MRHSIIARLVMMFAAAALVIFSLIGGVLYAVVKNELLRHERDGLVTTFNDIEYMVSRVGT 60 M+ S+ +RLV+MFA AA F+L G LY V+ +L R ++D L TT +++ Y ++R G Sbjct: 1 MKSSLKSRLVVMFAVAAAATFALTGVALYGVLDRQLDRIQQDALRTTAHEVSYSLTRSGD 60 Query: 61 VERWARVQTKLDTLTPADGKVRFWVFSDDPQFSYGKDLAELHDFDYDPNNIGRLRIKGKE 120 ERW R + KLDTLTPADG +RFWV SDDP + YGK LA++ + + G + + +E Sbjct: 61 PERWGRFKAKLDTLTPADGSLRFWVLSDDPAYEYGKGLADVDRLERHADGFGTITLPDRE 120 Query: 121 FPMHTLTKVLPAYLDRPAIRLTIGVDTEPYFETLRTFVIAMIGLSLAGIFLVILFGYWIA 180 + T+T + A+ RP +RL +G+D+ PY TLR F+ AM GLSL I LV L G+W+A Sbjct: 121 NELLTITVTVEAFQQRPRVRLIVGMDSAPYAHTLRYFLWAMAGLSLTAILLVGLLGFWVA 180 Query: 181 RAGLQPLKKMSDKAQTLSPQTLSERLTVSALPDELSDLAQAFNGALDRMENAYKQLEAFN 240 R GL+PL ++S +A+ L P LS+RL+++ALP EL DLA +FNGAL R+E AY QLE FN Sbjct: 181 RLGLRPLNRLSAEARALRPSALSQRLSMAALPVELEDLATSFNGALARLEGAYNQLEDFN 240 Query: 241 ADVAHELRTPLANLIGETQVALSRERSAPEFEIVLQSNLEELDRLRSIINDMLFLARCDQ 300 ADVAHELRTPL NLIG+TQVALSR R + E VLQSNLEELDRLR+++NDMLFLAR DQ Sbjct: 241 ADVAHELRTPLTNLIGQTQVALSRPRGSGELREVLQSNLEELDRLRAMVNDMLFLARADQ 300 Query: 301 GEAATSLVYTAIADEVQKTIEFFEFVLDEMQMSVEVVGDVDAKSMIETALFRRALTNLLQ 360 GEAAT ++ +ADEV KT+EFFEF+LDE M V + G+ DA ++I+TALFRRA+TNLLQ Sbjct: 301 GEAATGRIHAVLADEVGKTVEFFEFLLDEAGMRVRIQGERDAVALIDTALFRRAVTNLLQ 360 Query: 361 NAIQHSPAGARITVSIDAQQQDVQVAVSNPGEPIEQRHLPRLFDRFYRVDSARRDFDGV- 419 NAIQ+S AGA ITV I + ++VAVSNPG PI +HLP LF RFYRVD+A R DGV Sbjct: 361 NAIQYSSAGAEITVDIARRDGLLEVAVSNPGPPIAPQHLPHLFQRFYRVDAA-RGGDGVE 419 Query: 420 HGHGLGLAIVKAIALMHGGTAFASSRGGKTTIGFTVGGKAA 460 H HGLGLAIVKA+A MHGG+ A+S GG T + F+VG A Sbjct: 420 HSHGLGLAIVKAVAAMHGGSVSAASGGGVTRVAFSVGTAAG 460 >ref|YP_004156914.1| heavy metal sensor signal transduction histidine kinase [Variovorax paradoxus EPS] gb|ADU38803.1| heavy metal sensor signal transduction histidine kinase [Variovorax paradoxus EPS] Length = 464 Score = 475 bits (1222), Expect = e-132, Method: Compositional matrix adjust. Identities = 270/459 (58%), Positives = 342/459 (74%), Gaps = 6/459 (1%) Query: 1 MRHSIIARLVMMFAAAALVIFSLIGGVLYAVVKNELLRHERDGLVTTFNDIEYMVSRVGT 60 ++ SI RLV MFAAAAL F+LIG L+ V+ EL RH+ + L TT ++Y + +GT Sbjct: 4 VKGSITVRLVAMFAAAALATFALIGAALHGVLVRELERHQYEELDTTLKSLQYWIGAIGT 63 Query: 61 VERWARVQTKLDTLTPADGKVRFWVFSDDPQFSYGKDLAELHDFDYDPNNIGR---LRIK 117 +RW+RVQT++D LTP DG VRFWV SDDP+F YGK LAEL + N GR + + Sbjct: 64 ADRWSRVQTRMDALTPEDGSVRFWVLSDDPRFQYGKGLAELDGLTREAN--GRSSSILLP 121 Query: 118 GKEFPMHTLTKVLPAYLDRPAIRLTIGVDTEPYFETLRTFVIAMIGLSLAGIFLVILFGY 177 G+E P TL+ +P + RPA+RL +G ++EPY T +TF+ A++ L L G+ +V+L GY Sbjct: 122 GQERPFRTLSVHIPPFEGRPAVRLIVGRNSEPYERTRKTFLSALLMLGLGGVLVVVLAGY 181 Query: 178 WIARAGLQPLKKMSDKAQTLSPQTLSERLTVSALPDELSDLAQAFNGALDRMENAYKQLE 237 WIAR GL+PL+++S +AQ L P+TLS+RL +ALP ELS LA+AFNGAL R+E AY QLE Sbjct: 182 WIARVGLRPLERLSGEAQALRPKTLSQRLQTTALPVELSALAEAFNGALSRLEEAYGQLE 241 Query: 238 AFNADVAHELRTPLANLIGETQVALSRERSAPEFEIVLQSNLEELDRLRSIINDMLFLAR 297 AFNADVAHELRTPLANLIG TQVALSR+RSA +FE VLQ+NLE+L+RLRSI+NDMLFLAR Sbjct: 242 AFNADVAHELRTPLANLIGSTQVALSRQRSAGDFEEVLQANLEDLERLRSIVNDMLFLAR 301 Query: 298 CDQGEAATSLVYTAIADEVQKTIEFFEFVLDEMQMSVEVVGDVDAKSMIETALFRRALTN 357 D+GE AT LV T +A EV+KTI+FFEFVLDE + V + GDV A++ +E+ALFRRA++N Sbjct: 302 ADRGEVATGLVLTPVALEVRKTIDFFEFVLDESRTQVGIAGDVQAEARLESALFRRAMSN 361 Query: 358 LLQNAIQHSPAGARITVSIDAQQQDVQVAVSNPGEPIEQRHLPRLFDRFYRVDSARRD-F 416 LLQNAI+HS GA+ITV++ +AVSNPG I++ HL LFDRFYRVD+AR D Sbjct: 362 LLQNAIEHSTPGAQITVTLREGPAATWIAVSNPGAAIDEAHLQHLFDRFYRVDAARNDGG 421 Query: 417 DGVHGHGLGLAIVKAIALMHGGTAFASSRGGKTTIGFTV 455 HGHGLGLAIVKA+A MHGG ASS GG T F+V Sbjct: 422 GEHHGHGLGLAIVKAVASMHGGQVSASSEGGVNTFAFSV 460