BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0007.0186.p (365 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_004152688.1| alcohol dehydrogenase zinc-binding domain-co... 611 e-173 ref|YP_002942270.1| alcohol dehydrogenase GroES domain-containin... 601 e-170 ref|ZP_02355713.1| oxidoreductase, zinc-binding dehydrogenase fa... 594 e-168 ref|YP_442953.1| zinc-binding dehydrogenase family oxidoreductas... 592 e-167 ref|ZP_02362853.1| oxidoreductase, zinc-binding dehydrogenase fa... 592 e-167 >ref|YP_004152688.1| alcohol dehydrogenase zinc-binding domain-containing protein [Variovorax paradoxus EPS] gb|ADU34577.1| Alcohol dehydrogenase zinc-binding domain protein [Variovorax paradoxus EPS] Length = 376 Score = 611 bits (1575), Expect = e-173, Method: Compositional matrix adjust. Identities = 290/353 (82%), Positives = 316/353 (89%) Query: 8 MKAVVCHGPKDYRLQTIRCPQAGRNELVIRIGACGICASDCKCHSGAAMFWGGDGQDSWV 67 M+AVVCHGPKDYRL+T+ P GRNEL+I I ACGICASDCKCHSGA MFWGGDGQ SWV Sbjct: 20 MQAVVCHGPKDYRLETVAMPTIGRNELLISIAACGICASDCKCHSGAKMFWGGDGQPSWV 79 Query: 68 KPPVVAGHEFFGYVAELGEGAAEHFGVQQGDRVIAEQIVPCEACLFCKTGKYWMCEVHNI 127 K PV+ GHEFFGYV LGEGAAEHFGV++GDRVIAEQIVPC C FC +GKYWMCEVHNI Sbjct: 80 KAPVIPGHEFFGYVEALGEGAAEHFGVEKGDRVIAEQIVPCGKCRFCTSGKYWMCEVHNI 139 Query: 128 FGFQREVADGGMAEYMRLPSNAVVHKIPMDMPLEDAAIIEPLSCAIHTVNRGDIQLDDVV 187 FGFQR VADGGMA+YMRLP + VHKIP + LEDAAIIEPLSCAIHTVNRGDIQLDDVV Sbjct: 140 FGFQRIVADGGMADYMRLPPTSRVHKIPDGISLEDAAIIEPLSCAIHTVNRGDIQLDDVV 199 Query: 188 VIAGAGPLGLMMTQVAKLKTPRKLVVVDLVPERLALAREFGADVVIDPAREDALAVIKGL 247 VIAGAGPLGLMM Q A+LKTP+KL+V+DLVPERLALA+EFGADV I+P E+A A++KGL Sbjct: 200 VIAGAGPLGLMMVQAARLKTPKKLIVIDLVPERLALAKEFGADVTINPKTENADAIVKGL 259 Query: 248 TGGYGCDVYIETTGVPAGVTQGLQLIRRLGRFVEFSVFGKETSADWSIIGDRKELDVRGA 307 T GYGCDVYIETTG P GVTQGL++IR+LGRFVEFSVFG ETSADWSIIGDRKELDVRGA Sbjct: 260 TEGYGCDVYIETTGAPIGVTQGLEMIRKLGRFVEFSVFGSETSADWSIIGDRKELDVRGA 319 Query: 308 HLGPYCYPVAIDLLARGLVTSKGIVTHSFPLEKWEEAFALANSVASIKVLLKP 360 HLGPYCYP+AIDLLARGLVTSKGIVTH FPL +WE AFALANS+ SIKVLLKP Sbjct: 320 HLGPYCYPIAIDLLARGLVTSKGIVTHDFPLTEWERAFALANSLDSIKVLLKP 372 >ref|YP_002942270.1| alcohol dehydrogenase GroES domain-containing protein [Variovorax paradoxus S110] gb|ACS17004.1| Alcohol dehydrogenase GroES domain protein [Variovorax paradoxus S110] Length = 379 Score = 601 bits (1549), Expect = e-170, Method: Compositional matrix adjust. Identities = 286/353 (81%), Positives = 312/353 (88%) Query: 8 MKAVVCHGPKDYRLQTIRCPQAGRNELVIRIGACGICASDCKCHSGAAMFWGGDGQDSWV 67 M+AVVCHGPKDYRL+T+ P G NEL+I I ACGICASDCKCHSGA MFWGGDGQ SWV Sbjct: 20 MQAVVCHGPKDYRLETVAMPGIGPNELLISIAACGICASDCKCHSGAKMFWGGDGQPSWV 79 Query: 68 KPPVVAGHEFFGYVAELGEGAAEHFGVQQGDRVIAEQIVPCEACLFCKTGKYWMCEVHNI 127 K PV+ GHEFFGYV LGEGAAEHFGV++GDRVIAEQIVPC C FC +GKYWMCEVHNI Sbjct: 80 KAPVIPGHEFFGYVEALGEGAAEHFGVEKGDRVIAEQIVPCGKCRFCTSGKYWMCEVHNI 139 Query: 128 FGFQREVADGGMAEYMRLPSNAVVHKIPMDMPLEDAAIIEPLSCAIHTVNRGDIQLDDVV 187 FGFQR VADGGMA+YMRLP + VH+IP + LEDAAIIEPLSCAIHTVNRGDIQLDDVV Sbjct: 140 FGFQRIVADGGMADYMRLPPTSRVHRIPDGISLEDAAIIEPLSCAIHTVNRGDIQLDDVV 199 Query: 188 VIAGAGPLGLMMTQVAKLKTPRKLVVVDLVPERLALAREFGADVVIDPAREDALAVIKGL 247 VIAGAGPLGLMM Q A LKTP+KL+V+DLVPERLALA++FGADV ID E+A A++KGL Sbjct: 200 VIAGAGPLGLMMVQAAHLKTPKKLIVIDLVPERLALAKKFGADVTIDARTENADAIVKGL 259 Query: 248 TGGYGCDVYIETTGVPAGVTQGLQLIRRLGRFVEFSVFGKETSADWSIIGDRKELDVRGA 307 T GYGCDVYIETTG P GVTQGL++IR+LGRFVEFSVFG ETSADWSIIGDRKELDVRGA Sbjct: 260 TEGYGCDVYIETTGAPIGVTQGLEMIRKLGRFVEFSVFGSETSADWSIIGDRKELDVRGA 319 Query: 308 HLGPYCYPVAIDLLARGLVTSKGIVTHSFPLEKWEEAFALANSVASIKVLLKP 360 HLGPYCYP+AIDLLARGLVTSKGIVTH FPL +WE AF LANS+ SIKVLLKP Sbjct: 320 HLGPYCYPIAIDLLARGLVTSKGIVTHDFPLTEWERAFTLANSLDSIKVLLKP 372 >ref|ZP_02355713.1| oxidoreductase, zinc-binding dehydrogenase family protein [Burkholderia oklahomensis EO147] Length = 367 Score = 594 bits (1531), Expect = e-168, Method: Compositional matrix adjust. Identities = 282/353 (79%), Positives = 317/353 (89%), Gaps = 2/353 (0%) Query: 8 MKAVVCHGPKDYRLQTIRCPQAGRNELVIRIGACGICASDCKCHSGAAMFWGGDGQDSWV 67 M A+VCH P+DYR++ + P+A ELVIRIGACGICASDCKCHSGA MFWGG WV Sbjct: 15 MTAIVCHAPEDYRVERVTKPRAAARELVIRIGACGICASDCKCHSGAKMFWGG--PSPWV 72 Query: 68 KPPVVAGHEFFGYVAELGEGAAEHFGVQQGDRVIAEQIVPCEACLFCKTGKYWMCEVHNI 127 K PV+ GHEFFGYV ELGEGAAEHFGV G+RVIAEQIVPC C +CK+G+YWMCEVH+I Sbjct: 73 KAPVIPGHEFFGYVEELGEGAAEHFGVALGERVIAEQIVPCGKCRYCKSGQYWMCEVHDI 132 Query: 128 FGFQREVADGGMAEYMRLPSNAVVHKIPMDMPLEDAAIIEPLSCAIHTVNRGDIQLDDVV 187 FGFQREVADGGMAEYMR+P A+VHKIP+ + LEDAAIIEPL+CAIHTVNRGD+QLDDVV Sbjct: 133 FGFQREVADGGMAEYMRIPPTAIVHKIPLGISLEDAAIIEPLACAIHTVNRGDLQLDDVV 192 Query: 188 VIAGAGPLGLMMTQVAKLKTPRKLVVVDLVPERLALAREFGADVVIDPAREDALAVIKGL 247 VIAGAGPLGLMMTQVAKLKTP++LVV+DLV ERLALARE+GADV IDP R+DALA+++ L Sbjct: 193 VIAGAGPLGLMMTQVAKLKTPKRLVVIDLVAERLALAREYGADVTIDPTRDDALAIVRDL 252 Query: 248 TGGYGCDVYIETTGVPAGVTQGLQLIRRLGRFVEFSVFGKETSADWSIIGDRKELDVRGA 307 TGGYGCDVYIETTGVPAGVTQG+ LIR+LGRFVEFSVFGK+T+ADWSIIGDRKELDVRGA Sbjct: 253 TGGYGCDVYIETTGVPAGVTQGMDLIRKLGRFVEFSVFGKDTTADWSIIGDRKELDVRGA 312 Query: 308 HLGPYCYPVAIDLLARGLVTSKGIVTHSFPLEKWEEAFALANSVASIKVLLKP 360 HLGPYCYPVAIDLLARGLVTSKGIVTH F L++W+EA +ANS+ SIKVLLKP Sbjct: 313 HLGPYCYPVAIDLLARGLVTSKGIVTHGFSLDEWDEAIRVANSLDSIKVLLKP 365 >ref|YP_442953.1| zinc-binding dehydrogenase family oxidoreductase [Burkholderia thailandensis E264] ref|ZP_02388718.1| oxidoreductase, zinc-binding dehydrogenase family protein [Burkholderia thailandensis Bt4] ref|ZP_05587436.1| zinc-binding dehydrogenase family oxidoreductase [Burkholderia thailandensis E264] gb|ABC37771.1| oxidoreductase, zinc-binding dehydrogenase family [Burkholderia thailandensis E264] Length = 363 Score = 592 bits (1527), Expect = e-167, Method: Compositional matrix adjust. Identities = 283/353 (80%), Positives = 315/353 (89%), Gaps = 2/353 (0%) Query: 8 MKAVVCHGPKDYRLQTIRCPQAGRNELVIRIGACGICASDCKCHSGAAMFWGGDGQDSWV 67 M A+VCH P+DYR++ + P+A ELVIRIGACGICASDCKCHSGA MFWGG WV Sbjct: 11 MTAIVCHAPEDYRVERVAKPRANARELVIRIGACGICASDCKCHSGAKMFWGG--PSPWV 68 Query: 68 KPPVVAGHEFFGYVAELGEGAAEHFGVQQGDRVIAEQIVPCEACLFCKTGKYWMCEVHNI 127 K PV+ GHEFFG+V ELGEGAAEHFGV GDRVIAEQIVPC C +CK+G+YWMCEVHNI Sbjct: 69 KAPVIPGHEFFGHVEELGEGAAEHFGVALGDRVIAEQIVPCGNCRYCKSGQYWMCEVHNI 128 Query: 128 FGFQREVADGGMAEYMRLPSNAVVHKIPMDMPLEDAAIIEPLSCAIHTVNRGDIQLDDVV 187 FGFQREVADGGMAEYMR+PS A+VH+IP+ + LEDAAIIEPL+CAIHTVNRGDIQLDDVV Sbjct: 129 FGFQREVADGGMAEYMRIPSTAIVHRIPLGISLEDAAIIEPLACAIHTVNRGDIQLDDVV 188 Query: 188 VIAGAGPLGLMMTQVAKLKTPRKLVVVDLVPERLALAREFGADVVIDPAREDALAVIKGL 247 VIAGAGPLGLMMTQVAKLKTP++LVV+D V ERLALARE+GADV IDP REDALA++ L Sbjct: 189 VIAGAGPLGLMMTQVAKLKTPKRLVVIDPVGERLALAREYGADVTIDPTREDALAIVHEL 248 Query: 248 TGGYGCDVYIETTGVPAGVTQGLQLIRRLGRFVEFSVFGKETSADWSIIGDRKELDVRGA 307 TGGYGCDVYIETTGVPAGVTQG+ LIR+LGRFVEFSVFGK+T+ DWSIIGDRKELDVRGA Sbjct: 249 TGGYGCDVYIETTGVPAGVTQGMSLIRKLGRFVEFSVFGKDTALDWSIIGDRKELDVRGA 308 Query: 308 HLGPYCYPVAIDLLARGLVTSKGIVTHSFPLEKWEEAFALANSVASIKVLLKP 360 HLGPYCYPVAIDLLARGLVTSKGIVTH F LE+W+EA +ANS+ SIKVL+KP Sbjct: 309 HLGPYCYPVAIDLLARGLVTSKGIVTHGFSLEEWDEAIRVANSLGSIKVLMKP 361 >ref|ZP_02362853.1| oxidoreductase, zinc-binding dehydrogenase family protein [Burkholderia oklahomensis C6786] Length = 367 Score = 592 bits (1527), Expect = e-167, Method: Compositional matrix adjust. Identities = 281/353 (79%), Positives = 316/353 (89%), Gaps = 2/353 (0%) Query: 8 MKAVVCHGPKDYRLQTIRCPQAGRNELVIRIGACGICASDCKCHSGAAMFWGGDGQDSWV 67 M A+VCH P+DYR++ + P+A ELVIRIGACGICASDCKCHSGA MFWGG WV Sbjct: 15 MTAIVCHAPEDYRVERVTKPRAAARELVIRIGACGICASDCKCHSGAKMFWGG--PSPWV 72 Query: 68 KPPVVAGHEFFGYVAELGEGAAEHFGVQQGDRVIAEQIVPCEACLFCKTGKYWMCEVHNI 127 K PV+ GHEFFGYV ELGEGAAEHFGV G+RVIAEQIVPC C +CK+G+YWMCEVH+I Sbjct: 73 KAPVIPGHEFFGYVEELGEGAAEHFGVALGERVIAEQIVPCGKCRYCKSGQYWMCEVHDI 132 Query: 128 FGFQREVADGGMAEYMRLPSNAVVHKIPMDMPLEDAAIIEPLSCAIHTVNRGDIQLDDVV 187 FGFQREVADGGMAEYMR+P A+VHKIP+ + LEDAAIIEPL+CAIHTVNRGD+QLDDVV Sbjct: 133 FGFQREVADGGMAEYMRIPPTAIVHKIPLGISLEDAAIIEPLACAIHTVNRGDLQLDDVV 192 Query: 188 VIAGAGPLGLMMTQVAKLKTPRKLVVVDLVPERLALAREFGADVVIDPAREDALAVIKGL 247 VIAGAGPLGLMMTQVAKLKTP++LVV+DLV ERLALARE+GADV IDP R+DALA+++ L Sbjct: 193 VIAGAGPLGLMMTQVAKLKTPKRLVVIDLVAERLALAREYGADVTIDPTRDDALAIVRDL 252 Query: 248 TGGYGCDVYIETTGVPAGVTQGLQLIRRLGRFVEFSVFGKETSADWSIIGDRKELDVRGA 307 TGGYGCDVYIETTGVPAGVTQG+ LIR+LGRFVEFSVFGK+T+ DWSIIGDRKELDVRGA Sbjct: 253 TGGYGCDVYIETTGVPAGVTQGMDLIRKLGRFVEFSVFGKDTTVDWSIIGDRKELDVRGA 312 Query: 308 HLGPYCYPVAIDLLARGLVTSKGIVTHSFPLEKWEEAFALANSVASIKVLLKP 360 HLGPYCYPVAIDLLARGLVTSKGIVTH F L++W+EA +ANS+ SIKVLLKP Sbjct: 313 HLGPYCYPVAIDLLARGLVTSKGIVTHGFSLDEWDEAIRVANSLDSIKVLLKP 365