BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0007.0052.p (384 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_001611350.1| two-component hybrid sensor and regulator [S... 379 e-103 ref|YP_001378859.1| histidine kinase [Anaeromyxobacter sp. Fw109... 338 7e-91 ref|ZP_02731339.1| multi-sensor hybrid histidine kinase [Gemmata... 328 8e-88 ref|ZP_02736102.1| multi-sensor hybrid histidine kinase [Gemmata... 328 1e-87 ref|ZP_02881279.1| PAS/PAC sensor hybrid histidine kinase [Burkh... 325 6e-87 >ref|YP_001611350.1| two-component hybrid sensor and regulator [Sorangium cellulosum 'So ce 56'] emb|CAN90870.1| two-component hybrid sensor and regulator [Sorangium cellulosum 'So ce 56'] Length = 1307 Score = 379 bits (974), Expect = e-103, Method: Compositional matrix adjust. Identities = 201/358 (56%), Positives = 253/358 (70%), Gaps = 5/358 (1%) Query: 1 MLGHELRNPLTPILTAVHLMRLRGGGGMEKECSVIERQARHLVRLVDDLLDVSRVAQGKI 60 MLGHELRNPL PI+TA+HLMRLR GG E+E VIERQ +HL LVDDLLDVSR+ +GK+ Sbjct: 943 MLGHELRNPLAPIVTALHLMRLRAGGHAERERLVIERQIKHLTALVDDLLDVSRITRGKV 1002 Query: 61 NLQKKKLEIADIISKAIETASPLLEERQHRLTVNVPAQGLQVHADPERLTQVLANLLTNA 120 L+K+++EIAD+++KA+E ASPLLE+R+H LTV VP+ GL V D RL QV++NLLTNA Sbjct: 1003 ELKKQRIEIADVVAKAVELASPLLEQRRHHLTVTVPSSGLAVEGDVTRLAQVVSNLLTNA 1062 Query: 121 CKYTENRGHIRVDAMLDNNQIVVEIRDNGIGIRADMLPHVFEMFAQETQAIDRAGGGLGL 180 KYTE+ G I V A ++ + +RDNGIGI +MLP VFE F QE QA+DR+ GGLGL Sbjct: 1063 AKYTESGGEIAVRAGRVEGEVALSVRDNGIGIAPEMLPSVFERFVQERQALDRSQGGLGL 1122 Query: 181 GLAIVRSLTELHGGTVHVFSAGPGTGSVFTIKLPAVLSDATPILLPLTPDNLLGLQ---P 237 GLAIV +L +HGG V S G G GS FTI+LPA +P P + G Q Sbjct: 1123 GLAIVHNLIAMHGGRVSAHSEGRGRGSEFTIRLPAAADVRSPEAGPAR--WMAGTQATPS 1180 Query: 238 LEEGCPILIVDDNLDAAQILGELLTMQGHEIRIAYDGPSALDIVKDFTPRIALLDIGLPI 297 L + IL+VDDNLDA ++L E L G+ R+A DGPSAL I ++F P +ALLDIGLP+ Sbjct: 1181 LVDRRRILLVDDNLDAVELLAESLGAMGYTTRVAPDGPSALRIAEEFAPDVALLDIGLPV 1240 Query: 298 MDGYEVAGHLRAMPHLEGISLIALTGYGQASDKLRSLRAGFDHHLVKPVDIDVVEELI 355 MDGYE+A LR P E + LIA+TGYGQ +D RS AGF+ HLVKP+ I+ + L+ Sbjct: 1241 MDGYELARRLREQPAGERVRLIAITGYGQEADFRRSEGAGFETHLVKPIQIERLTSLL 1298 Score = 119 bits (298), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 104/382 (27%), Positives = 162/382 (42%), Gaps = 40/382 (10%) Query: 2 LGHELRNPLTPILTAVHLMRLRGGGGMEKE-CSVIERQARHLVRLVDDLLDVSRVAQGKI 60 + HE R PLT +L + + E S+ R A L++LV+ LLD SR+ G+ Sbjct: 379 VSHEFRTPLTLMLGPMEDALASPERALCGEHLSLAYRNALRLLKLVNALLDFSRLEMGRA 438 Query: 61 NLQKKKLEIADIISKAIETASPLLEERQHRLTVNVPAQGLQVHADPERLTQVLANLLTNA 120 ++A + +E V+ P V D + +++ NLL+NA Sbjct: 439 QASYDPTDLAGLTVDLASAFRSAIERAGLAFKVDCPELPEPVFVDRDMWEKIVLNLLSNA 498 Query: 121 CKYTENRGHIRVDAMLDNNQIVVEIRDNGIGIRADMLPHVFEMFAQETQAIDRAGGGLGL 180 K+T + G I + +Q+ + +RD G GI LPH+FE F + A R G G+ Sbjct: 499 LKFTFD-GEILLLLRAREDQVELVVRDTGTGIPEHELPHLFERFHRVQGARARTHEGSGI 557 Query: 181 GLAIVRSLTELHGGTVHVFSAGPGTGSVFTIKLP--------------AVLSDATPILLP 226 GLA+V L LHGG++ S G G+ FTI +P LS P Sbjct: 558 GLALVHELVRLHGGSIRAESR-LGEGTAFTIAIPRGSAHLPAERIHAEKTLSSTATGAAP 616 Query: 227 LTPDNLLGLQ----------------------PLEEGCPILIVDDNLDAAQILGELLTMQ 264 + L PL+ IL+ DDN D + +L + Sbjct: 617 YVEEALRWQLAAEAPALALASADRVESDHLSVPLDPSARILLADDNADMRMYVRRILDAR 676 Query: 265 GHEIRIAYDGPSALDIVKDFTPRIALLDIGLPIMDGYEVAGHLRAMPHLEGISLIALTGY 324 + DG +ALD+ + P + + D+ +P +DG+ + LRA P + +I L+ Sbjct: 677 -WTVEAVSDGAAALDVARRSPPDLVIADVMMPGLDGFGLLRALRADPVTRCVPVIMLSAR 735 Query: 325 GQASDKLRSLRAGFDHHLVKPV 346 ++ L AG D +LVKP Sbjct: 736 AGEESRVEGLAAGADDYLVKPF 757 >ref|YP_001378859.1| histidine kinase [Anaeromyxobacter sp. Fw109-5] gb|ABS25875.1| histidine kinase [Anaeromyxobacter sp. Fw109-5] Length = 755 Score = 338 bits (868), Expect = 7e-91, Method: Compositional matrix adjust. Identities = 184/348 (52%), Positives = 243/348 (69%), Gaps = 6/348 (1%) Query: 1 MLGHELRNPLTPILTAVHLMRLRGGGGMEKECSVIERQARHLVRLVDDLLDVSRVAQGKI 60 MLGHELRNPL+PI+TA+ L++LRG G +E S+IERQ H+ RLV+DLLDVSR+ +GKI Sbjct: 392 MLGHELRNPLSPIVTALQLIKLRGDG-QPREYSIIERQVSHMSRLVEDLLDVSRITRGKI 450 Query: 61 NLQKKKLEIADIISKAIETASPLLEERQHRLTVNVPAQGLQVHADPERLTQVLANLLTNA 120 LQ + LE++ +++KA+E A PLLE R HRL V+VPA+GL V DP RL Q++ANLLTNA Sbjct: 451 VLQPELLELSSVVAKALEMAGPLLEARAHRLAVDVPAEGLPVRGDPVRLAQIVANLLTNA 510 Query: 121 CKYTENRGHIRVDAMLDNNQIVVEIRDNGIGIRADMLPHVFEMFAQETQAIDRAGGGLGL 180 KYT GH+ V A +I + + D+G G+ ++LP +F++F Q +A DR GGLGL Sbjct: 511 AKYTPPGGHVEVWAGRHGAEISLTVSDDGQGLSPELLPRLFDLFVQGPRAPDRHEGGLGL 570 Query: 181 GLAIVRSLTELHGGTVHVFSAGPGTGSVFTIKLPAVLSDATPILLPLTPDNL-LGLQPLE 239 GLA+V+SL HGGTV SAG G GS FT++LPA ++A P L P L +PL Sbjct: 571 GLAVVKSLVTAHGGTVEAQSAGLGRGSTFTVRLPAAAAEAAPPALGPRPGALRRAARPLR 630 Query: 240 EGCPILIVDDNLDAAQILGELLTMQGHEIRIAYDGPSALDIVKDFTPRIALLDIGLPIMD 299 +L+VDDN DAA++L +L+ GH +R A+DG AL + FTP +A+LDIGLP+MD Sbjct: 631 ----VLVVDDNADAAELLAAVLSAAGHAVRAAHDGVGALAALDQFTPEVAVLDIGLPVMD 686 Query: 300 GYEVAGHLRAMPHLEGISLIALTGYGQASDKLRSLRAGFDHHLVKPVD 347 G+E+A +R + IALTGYGQA+D RS AGF+HHLVKPVD Sbjct: 687 GHELAARIRDRMGAAPPAFIALTGYGQATDLARSRAAGFEHHLVKPVD 734 >ref|ZP_02731339.1| multi-sensor hybrid histidine kinase [Gemmata obscuriglobus UQM 2246] Length = 682 Score = 328 bits (842), Expect = 8e-88, Method: Compositional matrix adjust. Identities = 174/371 (46%), Positives = 240/371 (64%), Gaps = 21/371 (5%) Query: 1 MLGHELRNPLTPILTAVHLMRLRGGGG--MEKECSVIERQARHLVRLVDDLLDVSRVAQG 58 ML HELRNPL P+ AV++++ + + ++ RQ + LVDDLLDVSR+ G Sbjct: 321 MLAHELRNPLAPVRNAVYVLQSTKSDDPDVARLTGILGRQVGQMAHLVDDLLDVSRLTSG 380 Query: 59 KINLQKKKLEIADIISKAIETASPLLEERQHRLTVNVPAQGLQVHADPERLTQVLANLLT 118 K+ L ++++ +AD I++A+ETA PL+E R+H L V+VP + + ADP RLTQ+ NLL Sbjct: 381 KVTLHRERVALADAIARAVETARPLIESRRHELIVSVPPDPIPLDADPTRLTQIFGNLLN 440 Query: 119 NACKYTENRGHIRVDAMLDNNQIVVEIRDNGIGIRADMLPHVFEMFAQETQAIDRAGGGL 178 NA KYT+ G I + A + VV +RDNGIG+ +ML F++F QE + +DRA GGL Sbjct: 441 NAAKYTDPGGRIELSAAREGGGAVVRVRDNGIGLSPEMLLRAFDLFTQEPRTLDRAQGGL 500 Query: 179 GLGLAIVRSLTELHGGTVHVFSAGPGTGSVFTIKLPAVLSDATPILLPLTPDNLLGLQPL 238 G+GL +VR+L ELHGG+V SAGPG GS F ++LPA+ + G +P Sbjct: 501 GIGLTLVRNLVELHGGSVEAHSAGPGRGSEFVVRLPALGTGTA------------GTRPN 548 Query: 239 EE---GCP----ILIVDDNLDAAQILGELLTMQGHEIRIAYDGPSALDIVKDFTPRIALL 291 E P +LIVDDN+D+A+ L ELL++ GH +R A+DGP+AL P + LL Sbjct: 549 GEPTHAAPATHRLLIVDDNVDSAESLAELLSLSGHTVRTAHDGPAALRDAAAHPPGVVLL 608 Query: 292 DIGLPIMDGYEVAGHLRAMPHLEGISLIALTGYGQASDKLRSLRAGFDHHLVKPVDIDVV 351 DIGLP M GYEVA LR +P L ++LIA+TGYGQ D+ RS AGF+HHLVKPVD++ V Sbjct: 609 DIGLPRMSGYEVATRLRQIPGLRDVTLIAMTGYGQDDDRRRSQEAGFNHHLVKPVDLNEV 668 Query: 352 EELIRSTLAAP 362 L++S A+P Sbjct: 669 TALLQSIPASP 679 >ref|ZP_02736102.1| multi-sensor hybrid histidine kinase [Gemmata obscuriglobus UQM 2246] Length = 536 Score = 328 bits (840), Expect = 1e-87, Method: Compositional matrix adjust. Identities = 174/356 (48%), Positives = 234/356 (65%), Gaps = 4/356 (1%) Query: 2 LGHELRNPLTPILTAVHLMRLR--GGGGMEKECSVIERQARHLVRLVDDLLDVSRVAQGK 59 L HELRNPL P+ VHLMR+ G E+ +++ERQ +V LVDDLLDV+R + GK Sbjct: 178 LAHELRNPLAPMRNGVHLMRVGQPDGPARERTLAMMERQLGQMVHLVDDLLDVARFSSGK 237 Query: 60 INLQKKKLEIADIISKAIETASPLLEERQHRLTVNVPAQGLQVHADPERLTQVLANLLTN 119 I L+K++LE+A ++ A+ET+ PL+E +H LTV+VPA+ L + D RLTQ+ ANLL N Sbjct: 238 IVLRKERLELAPVLGTAVETSRPLIEVGRHELTVDVPAEPLLLDGDRTRLTQIFANLLNN 297 Query: 120 ACKYTENRGHIRVDAMLDNNQIVVEIRDNGIGIRADMLPHVFEMFAQETQAIDRAGGGLG 179 A KYT G I + A + + VV + DNGIGI A+MLP VF++F Q A+DRA GGLG Sbjct: 298 AAKYTPKGGRITLSAAREGEKAVVRVGDNGIGISAEMLPQVFDLFTQVGSAVDRAQGGLG 357 Query: 180 LGLAIVRSLTELHGGTVHVFSAGPGTGSVFTIKLPAVLSDATPILLPLTPDNLLGLQPLE 239 +GL +V+ L LHGG + SAG G GS F ++LP V + P P L+ Sbjct: 358 IGLTLVKRLVALHGGEIAAHSAGEGKGSEFVVRLPLV--NRPAAAEPAAPVAAPPEPRLK 415 Query: 240 EGCPILIVDDNLDAAQILGELLTMQGHEIRIAYDGPSALDIVKDFTPRIALLDIGLPIMD 299 G P+LIVDDNLDAA+ L ELL M+GH +R A DG A+ ++ F PR+ LLD+GLP M Sbjct: 416 RGAPVLIVDDNLDAAESLAELLEMKGHTVRTARDGAEAMRVLGTFRPRLVLLDLGLPGMS 475 Query: 300 GYEVAGHLRAMPHLEGISLIALTGYGQASDKLRSLRAGFDHHLVKPVDIDVVEELI 355 GYE+A LR P L G++L ALTG+G+ D+ R+ AGFD+H VKP D+ V+ ++ Sbjct: 476 GYELAERLRDDPALSGMALAALTGWGKDEDRRRTKEAGFDYHFVKPADLSQVDAVL 531 >ref|ZP_02881279.1| PAS/PAC sensor hybrid histidine kinase [Burkholderia graminis C4D1M] gb|EDT12708.1| PAS/PAC sensor hybrid histidine kinase [Burkholderia graminis C4D1M] Length = 751 Score = 325 bits (834), Expect = 6e-87, Method: Compositional matrix adjust. Identities = 177/362 (48%), Positives = 234/362 (64%), Gaps = 23/362 (6%) Query: 1 MLGHELRNPLTPILTAVHLMRLRGGGGMEKECSVIERQARHLVRLVDDLLDVSRVAQGKI 60 MLGHELRNPL PI++A+ LM RG +E +VI+R HLVRLVDDLLDVSR+ +G + Sbjct: 380 MLGHELRNPLAPIVSALELMERRGTDSAARERAVIQRHVDHLVRLVDDLLDVSRIIRGNV 439 Query: 61 NLQKKKLEIADIISKAIETASPLLEERQHRLTVNVPAQGLQVHADPERLTQVLANLLTNA 120 L K+++++ ++I+KA+E S L+++R HRL + V + L+ ADP RL QV+ANLL NA Sbjct: 440 ELDKRRVDVHEVITKAVEMTSVLVQQRAHRLKIEVD-EALECVADPMRLAQVIANLLINA 498 Query: 121 CKYTENRGHIRVDAML-DNNQIVVEIRDNGIGIRADMLPHVFEMFAQETQAIDRAGGGLG 179 KYT+ G I V AM D + I + + DNG+GI D+LPHVF+ F Q TQ IDRA GGLG Sbjct: 499 AKYTQAGGEITVSAMAADADHIRIRVCDNGMGIAPDVLPHVFDTFYQGTQTIDRAEGGLG 558 Query: 180 LGLAIVRSLTELHGGTVHVFSAGPGTGSVFTIKLPAVLSDAT--------------PILL 225 +GLA+V++ +LHGG V S GPG GS FTI LP S+ T P+++ Sbjct: 559 IGLALVKNFVKLHGGHVEAASGGPGCGSEFTIVLPRASSETTTGNASKAIRVAEPAPVVV 618 Query: 226 PL-TPDNLLGLQPLEEGCPILIVDDNLDAAQILGELLTMQGHEIRIAYDGPSALDIVKDF 284 P PD+ + IL+VDDN+DAA L ELL GH ++ YD +AL F Sbjct: 619 PRDEPDSS------TQQRRILLVDDNVDAADALAELLRSYGHSVKTVYDPTAALAEANTF 672 Query: 285 TPRIALLDIGLPIMDGYEVAGHLRAMPHLEGISLIALTGYGQASDKLRSLRAGFDHHLVK 344 P +++LDIGLP+MDGYE+A LR L+ALTGYGQ +D+ RS AGFDHH VK Sbjct: 673 RPTVSVLDIGLPVMDGYELARQLRLRSGNRPCVLVALTGYGQKADRDRSHAAGFDHHFVK 732 Query: 345 PV 346 P+ Sbjct: 733 PL 734