BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0007.0003.p (389 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003776117.1| bifunctional glutathione-dependent formaldeh... 744 0.0 ref|YP_004753072.1| glutathione-dependent formaldehyde dehydroge... 698 0.0 ref|ZP_08275154.1| S-(hydroxymethyl)glutathione dehydrogenase [O... 694 0.0 ref|YP_004681366.1| S-(hydroxymethyl)glutathione dehydrogenase F... 683 0.0 ref|YP_001628757.1| alcohol dehydrogenase class III [Bordetella ... 682 0.0 >ref|YP_003776117.1| bifunctional glutathione-dependent formaldehyde dehydrogenase/alcohol dehydrogenase class III oxidoreductase [Herbaspirillum seropedicae SmR1] gb|ADJ64209.1| bifunctional: glutathione-dependent formaldehyde dehydrogenase and alcohol dehydrogenase class III oxidoreductase protein [Herbaspirillum seropedicae SmR1] Length = 368 Score = 744 bits (1922), Expect = 0.0, Method: Compositional matrix adjust. Identities = 361/368 (98%), Positives = 365/368 (99%) Query: 22 MKTKAAVAWQAGKPLTIEEVELGGPKAGEVLVEIKATGICHTDYYTLSGADPEGIFPAIL 81 MKT+AAVAWQAGKPLTIEEVELGGPKAGEVLVEIKATGICHTDYYTLSGADPEGIFPAIL Sbjct: 1 MKTRAAVAWQAGKPLTIEEVELGGPKAGEVLVEIKATGICHTDYYTLSGADPEGIFPAIL 60 Query: 82 GHEGAGVVVDVGPGVKSLKKDDHVIPLYTPECRECKFCLSQKTNLCQAIRSTQGRGLMPD 141 GHEGAGVVVDVGPGVKSLKKDDHVIPLYTPECRECKFCLSQKTNLCQAIR+TQGRGLMPD Sbjct: 61 GHEGAGVVVDVGPGVKSLKKDDHVIPLYTPECRECKFCLSQKTNLCQAIRATQGRGLMPD 120 Query: 142 ATSRFSLDGKPLFHYMGTSTFSNYIVVPEIALAKIREDAPFDKVCYIGCGVTTGVGAVLF 201 ATSRFSLDGKPLFHYMGTSTFSNYIVVPEIALAKIR DAPFDKVCYIGCGVTTGVGAVLF Sbjct: 121 ATSRFSLDGKPLFHYMGTSTFSNYIVVPEIALAKIRSDAPFDKVCYIGCGVTTGVGAVLF 180 Query: 202 TAKVEAGANVVVFGLGGIGLNVIQAARMVGANKIIGVDLNPGREAMARKFGMTDFINPKD 261 TAKVEAGANVVVFGLGGIGLNVIQAA+MVGANKIIGVDLNP REAMARKFGMTDFINPKD Sbjct: 181 TAKVEAGANVVVFGLGGIGLNVIQAAKMVGANKIIGVDLNPAREAMARKFGMTDFINPKD 240 Query: 262 VSNVVDAIIGLTDGGADYSFECIGNTTTMRQSLECCHKGWGQSIIIGVAAAGQEISTRPF 321 V NVVDAIIG+TDGGADYSFECIGNTTTMRQSLECCHKGWGQSIIIGVAAAGQEISTRPF Sbjct: 241 VPNVVDAIIGMTDGGADYSFECIGNTTTMRQSLECCHKGWGQSIIIGVAAAGQEISTRPF 300 Query: 322 QLVTGRVWKGSAFGGARGRTDVPKIVDWYMEGKLNIDDLITHKLPLERINEGFDLMKSGE 381 QLVTGRVWKGSAFGGARGRTDVPKIVDWYMEGKLNIDDLITHKLPLERINEGFDLMKSGE Sbjct: 301 QLVTGRVWKGSAFGGARGRTDVPKIVDWYMEGKLNIDDLITHKLPLERINEGFDLMKSGE 360 Query: 382 SIRSVVEF 389 SIRSVVEF Sbjct: 361 SIRSVVEF 368 >ref|YP_004753072.1| glutathione-dependent formaldehyde dehydrogenase [Collimonas fungivorans Ter331] gb|AEK62249.1| Alcohol dehydrogenase class III; Glutathione-dependent formaldehyde dehydrogenase [Collimonas fungivorans Ter331] Length = 368 Score = 698 bits (1801), Expect = 0.0, Method: Compositional matrix adjust. Identities = 343/368 (93%), Positives = 362/368 (98%) Query: 22 MKTKAAVAWQAGKPLTIEEVELGGPKAGEVLVEIKATGICHTDYYTLSGADPEGIFPAIL 81 MKTKAA+AW+AG+PLTIEEVELGGP+AGEVLVEIKATGICHTDYYTLSGADPEGIFP+IL Sbjct: 1 MKTKAAIAWKAGQPLTIEEVELGGPRAGEVLVEIKATGICHTDYYTLSGADPEGIFPSIL 60 Query: 82 GHEGAGVVVDVGPGVKSLKKDDHVIPLYTPECRECKFCLSQKTNLCQAIRSTQGRGLMPD 141 GHEGAGVVVDVGP VKSLKK+DHVIPLYTPECR+CKFCLSQKTNLCQ+IRSTQGRGLMPD Sbjct: 61 GHEGAGVVVDVGPDVKSLKKNDHVIPLYTPECRQCKFCLSQKTNLCQSIRSTQGRGLMPD 120 Query: 142 ATSRFSLDGKPLFHYMGTSTFSNYIVVPEIALAKIREDAPFDKVCYIGCGVTTGVGAVLF 201 ATSRFS+DGKP+FHYMGTSTFSNYIVVPEIALAKIREDAPFDKVCYIGCGVTTGVGAVLF Sbjct: 121 ATSRFSIDGKPIFHYMGTSTFSNYIVVPEIALAKIREDAPFDKVCYIGCGVTTGVGAVLF 180 Query: 202 TAKVEAGANVVVFGLGGIGLNVIQAARMVGANKIIGVDLNPGREAMARKFGMTDFINPKD 261 TAKVEAGANVVVFGLGGIGLNVIQAARMVGA+KIIGVD+NP REAMARKFGMT FIN K+ Sbjct: 181 TAKVEAGANVVVFGLGGIGLNVIQAARMVGADKIIGVDINPAREAMARKFGMTHFINAKE 240 Query: 262 VSNVVDAIIGLTDGGADYSFECIGNTTTMRQSLECCHKGWGQSIIIGVAAAGQEISTRPF 321 + NVVDAIIGLTDGGADYSFECIGNTTTMRQ+LECCHKGWGQSI+IGVAAAGQEISTRPF Sbjct: 241 IENVVDAIIGLTDGGADYSFECIGNTTTMRQALECCHKGWGQSIVIGVAAAGQEISTRPF 300 Query: 322 QLVTGRVWKGSAFGGARGRTDVPKIVDWYMEGKLNIDDLITHKLPLERINEGFDLMKSGE 381 QLVTGRVWKGSAFGGARGRTDVPKIVDWYM+GKLNIDDLITH+LPLERINEGFDLMKSGE Sbjct: 301 QLVTGRVWKGSAFGGARGRTDVPKIVDWYMDGKLNIDDLITHRLPLERINEGFDLMKSGE 360 Query: 382 SIRSVVEF 389 SIRSVV + Sbjct: 361 SIRSVVIY 368 >ref|ZP_08275154.1| S-(hydroxymethyl)glutathione dehydrogenase [Oxalobacteraceae bacterium IMCC9480] gb|EGF31366.1| S-(hydroxymethyl)glutathione dehydrogenase [Oxalobacteraceae bacterium IMCC9480] Length = 368 Score = 694 bits (1790), Expect = 0.0, Method: Compositional matrix adjust. Identities = 331/368 (89%), Positives = 353/368 (95%) Query: 22 MKTKAAVAWQAGKPLTIEEVELGGPKAGEVLVEIKATGICHTDYYTLSGADPEGIFPAIL 81 MKTKAAVAWQAG+PLTIEEVELGGP+AGEVLVE+KATGICHTDYYTLSGADPEG+FPAIL Sbjct: 1 MKTKAAVAWQAGRPLTIEEVELGGPRAGEVLVELKATGICHTDYYTLSGADPEGLFPAIL 60 Query: 82 GHEGAGVVVDVGPGVKSLKKDDHVIPLYTPECRECKFCLSQKTNLCQAIRSTQGRGLMPD 141 GHEGAG+VVDVGP VKS++KDDHVIPLYTPECR+CKFCLSQKTNLCQ+IRSTQG+GLMPD Sbjct: 61 GHEGAGIVVDVGPDVKSIRKDDHVIPLYTPECRQCKFCLSQKTNLCQSIRSTQGQGLMPD 120 Query: 142 ATSRFSLDGKPLFHYMGTSTFSNYIVVPEIALAKIREDAPFDKVCYIGCGVTTGVGAVLF 201 ATSRFSLDGKPLFHYMGTSTFSNYIVVPEIALAKIREDAPFDKVCYIGCGVTTGVGAV+F Sbjct: 121 ATSRFSLDGKPLFHYMGTSTFSNYIVVPEIALAKIREDAPFDKVCYIGCGVTTGVGAVIF 180 Query: 202 TAKVEAGANVVVFGLGGIGLNVIQAARMVGANKIIGVDLNPGREAMARKFGMTDFINPKD 261 TAKVE GA VVVFGLGGIGLNVIQAA+MVGA+KIIG+DLNP REAMARKFGMTDFINPKD Sbjct: 181 TAKVEFGATVVVFGLGGIGLNVIQAAKMVGASKIIGIDLNPAREAMARKFGMTDFINPKD 240 Query: 262 VSNVVDAIIGLTDGGADYSFECIGNTTTMRQSLECCHKGWGQSIIIGVAAAGQEISTRPF 321 V NVVD I+ LTDGGADYSFECIGNT MRQ+LEC HKGWGQ+I+IGVA AG EISTRPF Sbjct: 241 VENVVDRIVELTDGGADYSFECIGNTKVMRQALECTHKGWGQAIVIGVADAGAEISTRPF 300 Query: 322 QLVTGRVWKGSAFGGARGRTDVPKIVDWYMEGKLNIDDLITHKLPLERINEGFDLMKSGE 381 QLVTGR WKGSAFGGARGRTDVPKIVD YM+GKLNIDDLITH+LPLERINEGFDLMK+GE Sbjct: 301 QLVTGREWKGSAFGGARGRTDVPKIVDMYMDGKLNIDDLITHRLPLERINEGFDLMKAGE 360 Query: 382 SIRSVVEF 389 SIRSVV + Sbjct: 361 SIRSVVLY 368 >ref|YP_004681366.1| S-(hydroxymethyl)glutathione dehydrogenase FlhA [Cupriavidus necator N-1] gb|AEI80134.1| S-(hydroxymethyl)glutathione dehydrogenase FlhA [Cupriavidus necator N-1] Length = 368 Score = 683 bits (1762), Expect = 0.0, Method: Compositional matrix adjust. Identities = 328/368 (89%), Positives = 348/368 (94%) Query: 22 MKTKAAVAWQAGKPLTIEEVELGGPKAGEVLVEIKATGICHTDYYTLSGADPEGIFPAIL 81 MKTKAA+AW+AG PLTIE+V+L GP+AGEVLVE+KATGICHTDYYTLSGADPEGIFPAIL Sbjct: 1 MKTKAAIAWKAGAPLTIEDVDLDGPRAGEVLVEVKATGICHTDYYTLSGADPEGIFPAIL 60 Query: 82 GHEGAGVVVDVGPGVKSLKKDDHVIPLYTPECRECKFCLSQKTNLCQAIRSTQGRGLMPD 141 GHEGAG+V DVGPGV SLK DHVIPLYTPECR+CKFCLS+KTNLCQAIR+TQG+GLMPD Sbjct: 61 GHEGAGIVTDVGPGVTSLKPGDHVIPLYTPECRQCKFCLSRKTNLCQAIRATQGKGLMPD 120 Query: 142 ATSRFSLDGKPLFHYMGTSTFSNYIVVPEIALAKIREDAPFDKVCYIGCGVTTGVGAVLF 201 TSRFS+DGKP+FHYMGTSTF+N+IVVPEIALAKIR DAPFDKVCYIGCGVTTGVGAVLF Sbjct: 121 GTSRFSIDGKPIFHYMGTSTFANHIVVPEIALAKIRPDAPFDKVCYIGCGVTTGVGAVLF 180 Query: 202 TAKVEAGANVVVFGLGGIGLNVIQAARMVGANKIIGVDLNPGREAMARKFGMTDFINPKD 261 TAKVEAGANVVVFGLGGIGLNVIQAA+MVGA+KIIGVDLNPGREAMARKFGMT FINPKD Sbjct: 181 TAKVEAGANVVVFGLGGIGLNVIQAAKMVGADKIIGVDLNPGREAMARKFGMTHFINPKD 240 Query: 262 VSNVVDAIIGLTDGGADYSFECIGNTTTMRQSLECCHKGWGQSIIIGVAAAGQEISTRPF 321 V NVVD II LTDGGADYSFECIGNT MRQ+LECCHKGWG+SIIIGVA AG EISTRPF Sbjct: 241 VENVVDHIIQLTDGGADYSFECIGNTQVMRQALECCHKGWGKSIIIGVAEAGAEISTRPF 300 Query: 322 QLVTGRVWKGSAFGGARGRTDVPKIVDWYMEGKLNIDDLITHKLPLERINEGFDLMKSGE 381 QLVTGR WKGSAFGGARGRTDVPKIVDWYMEGKLNIDDLITH LPLERINEGFDLMK GE Sbjct: 301 QLVTGREWKGSAFGGARGRTDVPKIVDWYMEGKLNIDDLITHTLPLERINEGFDLMKRGE 360 Query: 382 SIRSVVEF 389 SIRSVV + Sbjct: 361 SIRSVVLY 368 >ref|YP_001628757.1| alcohol dehydrogenase class III [Bordetella petrii DSM 12804] emb|CAP40486.1| alcohol dehydrogenase class III [Bordetella petrii] Length = 368 Score = 682 bits (1761), Expect = 0.0, Method: Compositional matrix adjust. Identities = 324/368 (88%), Positives = 349/368 (94%) Query: 22 MKTKAAVAWQAGKPLTIEEVELGGPKAGEVLVEIKATGICHTDYYTLSGADPEGIFPAIL 81 MKTKAAVAW+AG PLTIEEV+L GP+AGEVL+E+KATGICHTDYYTLSGADPEG+FPAIL Sbjct: 1 MKTKAAVAWKAGAPLTIEEVDLEGPRAGEVLIEVKATGICHTDYYTLSGADPEGLFPAIL 60 Query: 82 GHEGAGVVVDVGPGVKSLKKDDHVIPLYTPECRECKFCLSQKTNLCQAIRSTQGRGLMPD 141 GHEGAG+VVDVG GV SLKK DHVIPLYTPECR+CKFCLS+KTNLCQAIR+TQG+GLMPD Sbjct: 61 GHEGAGIVVDVGAGVTSLKKGDHVIPLYTPECRQCKFCLSRKTNLCQAIRATQGKGLMPD 120 Query: 142 ATSRFSLDGKPLFHYMGTSTFSNYIVVPEIALAKIREDAPFDKVCYIGCGVTTGVGAVLF 201 ATSRFSL+GKPL HYMGTSTF+N+IVVPEIA+AK+REDAPFDK+CYIGCGVTTGVGAV++ Sbjct: 121 ATSRFSLNGKPLLHYMGTSTFANHIVVPEIAVAKVREDAPFDKICYIGCGVTTGVGAVVY 180 Query: 202 TAKVEAGANVVVFGLGGIGLNVIQAARMVGANKIIGVDLNPGREAMARKFGMTDFINPKD 261 TAKVEAGANVVVFGLGGIGLNVIQ ARMVGA+KIIGVDLNPGREAMARKFGMT F+NPKD Sbjct: 181 TAKVEAGANVVVFGLGGIGLNVIQGARMVGADKIIGVDLNPGREAMARKFGMTHFVNPKD 240 Query: 262 VSNVVDAIIGLTDGGADYSFECIGNTTTMRQSLECCHKGWGQSIIIGVAAAGQEISTRPF 321 V NVVD I+ LTDGGADYSFECIGNT MRQ+LECCHKGWGQSIIIGVA AG EISTRPF Sbjct: 241 VDNVVDHIVQLTDGGADYSFECIGNTQVMRQALECCHKGWGQSIIIGVAEAGAEISTRPF 300 Query: 322 QLVTGRVWKGSAFGGARGRTDVPKIVDWYMEGKLNIDDLITHKLPLERINEGFDLMKSGE 381 QLVTGR WKGSAFGGARGRTDVPKIVDWYMEGK+NIDDLITH LPLERINEGFDLMK GE Sbjct: 301 QLVTGRQWKGSAFGGARGRTDVPKIVDWYMEGKINIDDLITHTLPLERINEGFDLMKRGE 360 Query: 382 SIRSVVEF 389 SIRSVV + Sbjct: 361 SIRSVVLY 368