BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0006.0046.p (349 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|ZP_02735038.1| integral membrane sensor signal transduction ... 397 e-108 ref|ZP_08274512.1| multi-sensor signal transduction histidine ki... 321 1e-85 ref|YP_003243024.1| integral membrane sensor hybrid histidine ki... 122 1e-25 ref|ZP_08281064.1| ATPase/histidine kinase/DNA gyrase B/HSP90 do... 121 1e-25 ref|ZP_08134856.1| two component system sensor histidine kinase/... 120 4e-25 >ref|ZP_02735038.1| integral membrane sensor signal transduction histidine kinase [Gemmata obscuriglobus UQM 2246] Length = 359 Score = 397 bits (1021), Expect = e-108, Method: Compositional matrix adjust. Identities = 198/344 (57%), Positives = 253/344 (73%), Gaps = 2/344 (0%) Query: 2 VRALPSARNLSIPTLNDHVPALLDEIALAFRRNSDESIAEVLADGTPPEHGLQRLHNGYL 61 VR LPSAR+L PTLNDH+PA LDE+A R SDESI E + +GTP HG QR NG+ Sbjct: 16 VRKLPSARHLDTPTLNDHMPAFLDELAAVLRARSDESIHEAVCEGTPAIHGAQRADNGFD 75 Query: 62 IEEVVAEYNLLRGCIHDLASTHQINLQGKPFHVINLVFDSAIGLAVQTFSVNRALEVQRR 121 + EVVAEYN+LR C+++LA L + H++N + D AIG AV+T++ +ALEVQRR Sbjct: 76 VVEVVAEYNILRECVYELAEAGGKPLVRRSAHIVNRLIDGAIGSAVKTYATQKALEVQRR 135 Query: 122 REEYLSFIAHDLRTPLNAVALASKVLESTLGAQNADPRAARMIKVLQRNVQSMSGLVAKV 181 REEYL+F+AHDLRTPL+A++LA+ VLE G A + RM+K L+RNV + LV KV Sbjct: 136 REEYLAFVAHDLRTPLSAISLAAGVLELKFGTNEAGTQVGRMVKTLRRNVLHLGSLVDKV 195 Query: 182 IEENDNMKTESGVKLERRNIDLWPLVESMVYDLNPVAGTGSTRLLNDVPEDLVIYADANL 241 ++EN N++TE G+KLERR +DLWPLVE++V+DL+PVAGT ST+L N+VPEDLV+YADA+L Sbjct: 196 LDENTNLRTEVGLKLERRELDLWPLVEALVHDLHPVAGTDSTKLFNEVPEDLVVYADADL 255 Query: 242 LRRMMQNLIANAITHTPQGEVVIGAAPTLDGAGIECWVSDNGMGISKDRLALIFEKFETE 301 LRR+ QNLIANAI +TP G+V I +A ++G G EC V D G GI +RL +FE FET+ Sbjct: 256 LRRVFQNLIANAIKYTPVGDVTI-SARAVEG-GFECSVRDTGEGIPANRLDKVFEPFETD 313 Query: 302 TKDHGGLGLGLAIFKTFVEAHEGSFDVVSEPGKGSRFSFILPNR 345 GG+GLGLAI KTF+EAHEG+ V S G GS F F LP R Sbjct: 314 PNKQGGVGLGLAIVKTFIEAHEGTVGVESTVGAGSTFWFTLPAR 357 >ref|ZP_08274512.1| multi-sensor signal transduction histidine kinase [Oxalobacteraceae bacterium IMCC9480] gb|EGF32016.1| multi-sensor signal transduction histidine kinase [Oxalobacteraceae bacterium IMCC9480] Length = 259 Score = 321 bits (822), Expect = 1e-85, Method: Compositional matrix adjust. Identities = 152/259 (58%), Positives = 200/259 (77%) Query: 87 LQGKPFHVINLVFDSAIGLAVQTFSVNRALEVQRRREEYLSFIAHDLRTPLNAVALASKV 146 +QGKPFH++N V D AIG AVQ+++ RAL+VQ RRE+YL+F+AHDLRTPL+A++LA++V Sbjct: 1 MQGKPFHILNQVLDGAIGAAVQSYATQRALDVQTRREDYLAFVAHDLRTPLSAISLAARV 60 Query: 147 LESTLGAQNADPRAARMIKVLQRNVQSMSGLVAKVIEENDNMKTESGVKLERRNIDLWPL 206 LE ++ + +M+K L RNVQ +S LVA +++E+ N++T SGV L+ R+ DLWPL Sbjct: 61 LELSVHDPAKSKQTGQMLKTLHRNVQHLSSLVANILDESINLQTGSGVTLKCRHFDLWPL 120 Query: 207 VESMVYDLNPVAGTGSTRLLNDVPEDLVIYADANLLRRMMQNLIANAITHTPQGEVVIGA 266 VE+++ DLNPVAGTGSTRLLN+VPED IYADANLLRR++QNLIANAI +TP G+V I A Sbjct: 121 VEALIIDLNPVAGTGSTRLLNEVPEDQTIYADANLLRRILQNLIANAIHYTPHGDVTISA 180 Query: 267 APTLDGAGIECWVSDNGMGISKDRLALIFEKFETETKDHGGLGLGLAIFKTFVEAHEGSF 326 P+ DG GI C VSD G GI+ D L +F+KFE++ + G+GLGLAI KTFVEAH G+ Sbjct: 181 GPSGDGLGIACTVSDTGSGIAADLLDKVFDKFESDPANGNGMGLGLAIVKTFVEAHGGTV 240 Query: 327 DVVSEPGKGSRFSFILPNR 345 V SEP +GS F LP+R Sbjct: 241 RVDSEPDRGSVFRITLPDR 259 >ref|YP_003243024.1| integral membrane sensor hybrid histidine kinase [Paenibacillus sp. Y412MC10] gb|ACX65217.1| integral membrane sensor hybrid histidine kinase [Paenibacillus sp. Y412MC10] Length = 1017 Score = 122 bits (305), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 87/265 (32%), Positives = 146/265 (55%), Gaps = 19/265 (7%) Query: 92 FHVINLVFDSAIGLAVQT----FSVNRA----LEVQRRREEYLSFIAHDLRTPLNAV-AL 142 F V+ VF A+ L++++ F V R L + + ++E+L+ +H+LRTPL+ + L Sbjct: 362 FGVLGFVFLQALLLSMKSSRAFFQVERLSERLLTLDKLKDEFLAKTSHELRTPLHGIIGL 421 Query: 143 ASKVLESTLGAQNADPRAARMIKVLQRNVQSMSGLVAKVIEENDNMKTESGVKLERRNID 202 A +++ + G + ++++++ + Q ++ LV +++ + E G+ L N+ Sbjct: 422 ADALIDGSSGKLPSP--VIDLLRLMKVSGQRLAHLVNDILDFSKLKHQEIGLVLVTVNLR 479 Query: 203 LWPLVESMVYDLNPVAGTGSTRLLNDVPEDLVIYADANLLRRMMQNLIANAITHTPQGEV 262 L VE + LNP+A RL + +P+D+ + AD N L++++ NLI NAI +T G V Sbjct: 480 L--AVELTLQVLNPLAEKKGLRLSHQLPDDMYVMADENRLQQILHNLIGNAIAYTETGTV 537 Query: 263 VIGAAPTLDGAGIECWVSDNGMGISKDRLALIFEKFET----ETKDHGGLGLGLAIFKTF 318 + A L G + ++D+G+GIS+ L IFE FE + GG G+GL+I K Sbjct: 538 TV-TAKRLQGQ-VSVQITDSGIGISEADLDRIFESFEQINPLDRSQQGGTGIGLSITKKL 595 Query: 319 VEAHEGSFDVVSEPGKGSRFSFILP 343 VE H G V S G+GS FSF LP Sbjct: 596 VELHGGRIGVTSGVGEGSTFSFTLP 620 >ref|ZP_08281064.1| ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein [Paenibacillus sp. HGF5] gb|EGG35427.1| ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein [Paenibacillus sp. HGF5] Length = 1017 Score = 121 bits (304), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 86/265 (32%), Positives = 147/265 (55%), Gaps = 19/265 (7%) Query: 92 FHVINLVFDSAIGLAVQT----FSVNRA----LEVQRRREEYLSFIAHDLRTPLNAV-AL 142 F V+ VF A+ L++++ F V R L + + ++E+L+ +H+LRTPL+ + L Sbjct: 362 FGVLGFVFLQALLLSMKSSRAFFQVERLSERLLTLDKLKDEFLAKTSHELRTPLHGIIGL 421 Query: 143 ASKVLESTLGAQNADPRAARMIKVLQRNVQSMSGLVAKVIEENDNMKTESGVKLERRNID 202 A +++ + G + ++++++ + Q ++ LV +++ + E G+ L N+ Sbjct: 422 ADALIDGSSGKLPSP--VIDLLRLMKVSGQRLAHLVNDILDFSKLKHQEIGLVLVTVNLR 479 Query: 203 LWPLVESMVYDLNPVAGTGSTRLLNDVPEDLVIYADANLLRRMMQNLIANAITHTPQGEV 262 L VE + LNP+A RL + +P+D+ + AD N L++++ NLI NAI +T G V Sbjct: 480 L--AVELTLQVLNPLAEKKGLRLSHQLPDDMYVMADENRLQQILHNLIGNAIAYTETGAV 537 Query: 263 VIGAAPTLDGAGIECWVSDNGMGISKDRLALIFEKFET----ETKDHGGLGLGLAIFKTF 318 + A L G + ++D+G+GI++ L IFE FE + GG G+GL+I K Sbjct: 538 TV-TAKRLQGQ-LSIQITDSGIGIAEADLDRIFESFEQINPLDRSQQGGTGIGLSITKKL 595 Query: 319 VEAHEGSFDVVSEPGKGSRFSFILP 343 VE H+G V S G+GS FSF LP Sbjct: 596 VELHDGRIGVTSGLGEGSTFSFTLP 620 >ref|ZP_08134856.1| two component system sensor histidine kinase/response regulator hybrid [Prevotella multiformis DSM 16608] gb|EGC21315.1| two component system sensor histidine kinase/response regulator hybrid [Prevotella multiformis DSM 16608] Length = 878 Score = 120 bits (300), Expect = 4e-25, Method: Compositional matrix adjust. Identities = 82/259 (31%), Positives = 137/259 (52%), Gaps = 10/259 (3%) Query: 92 FHVINLVFDSAIGLAVQTFSVNRALEVQRR--REEYLSFIAHDLRTPLNAVALASKVLES 149 F VI ++ + A +T + R +E + + ++ + I+H+LRTPL +A +E Sbjct: 340 FSVIIILLVGIMVYAYRTTVMRRHIEEEATAAKLQFFTNISHELRTPLTLIA---DPVEY 396 Query: 150 TLGAQNADPRAARMIKVLQRNVQSMSGLVAKVIEENDNMKTESG-VKLERRNIDLWPLVE 208 + N P+ M++++QRNV +S LV++++ D K ++G ++L + DL + Sbjct: 397 IIHDPNLSPQQRGMLQIVQRNVAVLSRLVSEIL---DFRKVQNGKMQLHLSDFDLSECMR 453 Query: 209 SMVYDLNPVAGTGSTRLLNDVPEDLVIYADANLLRRMMQNLIANAITHTPQGEVVIGAAP 268 + + A L VPE + + AD + L R+ NL++NA+ +TP+G IG A Sbjct: 454 QWLGLFDTSARKKHITLQLHVPESIPMRADRDKLERICYNLLSNAMKYTPEGGC-IGFAA 512 Query: 269 TLDGAGIECWVSDNGMGISKDRLALIFEKFETETKDHGGLGLGLAIFKTFVEAHEGSFDV 328 +++ + VSDNG GI++D L +F++F G G+GLA+ K F E H G V Sbjct: 513 SVEADKVGIMVSDNGCGIAQDDLPYVFDRFYQAGNAGHGTGIGLALVKAFAELHHGQATV 572 Query: 329 VSEPGKGSRFSFILPNRPE 347 SE GKG F +P R E Sbjct: 573 ESEEGKGCTFVVSMPLRQE 591