BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0006.0031.p (770 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003775908.1| malto-oligosyltrehalose trehalohydrolase [He... 751 0.0 ref|YP_001892467.1| malto-oligosyltrehalose trehalohydrolase [Ra... 663 0.0 ref|ZP_07673852.1| 4-alpha-D-((1->4)-alpha-D-glucano)trehalose t... 656 0.0 ref|YP_003052329.1| malto-oligosyltrehalose trehalohydrolase [Me... 647 0.0 ref|YP_004040883.1| malto-oligosyltrehalose trehalohydrolase [Me... 643 0.0 >ref|YP_003775908.1| malto-oligosyltrehalose trehalohydrolase [Herbaspirillum seropedicae SmR1] gb|ADJ64000.1| malto-oligosyltrehalose trehalohydrolase protein [Herbaspirillum seropedicae SmR1] Length = 616 Score = 751 bits (1939), Expect = 0.0, Method: Compositional matrix adjust. Identities = 394/590 (66%), Positives = 454/590 (76%), Gaps = 26/590 (4%) Query: 13 NVRFHYRLPFGAEYLGNGRTSFRLWAPLAKTASVLIDGQRKVPMAAVDEGWFEVETDCEA 72 + RF + LPFGA+ GR FR+WAP A++ +V I G+ ++PM A +GWF +ET C+ Sbjct: 2 SARFSWNLPFGAQVTEPGRVRFRVWAPGARSVAVDITGRGRLPMDAEPQGWFALETACDP 61 Query: 73 RSQYRYVLMSQTNGEISVPDPASRAQAGDVHADSVVIDASAYEWQTLDWRGRPWHETVLY 132 + YRYV + + GE+ PDPASR QAGDV S+V+DA AY WQ WRGRPW ETVLY Sbjct: 62 GATYRYVFDTISQGELVAPDPASRGQAGDVFDPSLVVDAQAYVWQYPQWRGRPWEETVLY 121 Query: 133 ELHVGALGGFAGVLQRLPELAELGITAVELMPVAEFPGAYNWGYDGVLPYAPDASYGTPE 192 ELH GA+GGFAG+ QRL ELAELGITA+ELMPVAEFPGA+NWGYDGVLP+APDASYGTPE Sbjct: 122 ELHPGAMGGFAGIRQRLAELAELGITAIELMPVAEFPGAHNWGYDGVLPFAPDASYGTPE 181 Query: 193 QLKQLIDTAHGLGMMVFLDVVYNHFGPDGNYLNSYAAPFFRTDSTTPWGETIDFRRPEVA 252 QLK LIDTAHGLGMMVFLDVVYNHFGPDGNYL++YA FFR D T WG TIDFRRPEV Sbjct: 182 QLKALIDTAHGLGMMVFLDVVYNHFGPDGNYLHAYAPEFFRQDMQTLWGATIDFRRPEVD 241 Query: 253 DFFARNALYWLQEYRFDGLRLDAVHAISEQGWLRELARKVRRAIEQEDADIGLSRRHVHL 312 DFF +NALYWLQEYRFDGLRLDAVHAI E WL L +++R +IG +RHVHL Sbjct: 242 DFFTQNALYWLQEYRFDGLRLDAVHAICEPAWLERLGQRIR-------TEIG-GQRHVHL 293 Query: 313 VLEHDGNAASLLDGGTGKPGDGDK----YDAQWNDDGHHVLHVLLTGETGGYYSDYAVQP 368 VLEHDGNAA LL G G P D + YDAQWNDD HHVLHVLLTGE GYY+ YA +P Sbjct: 294 VLEHDGNAAHLL--GHGHPPDDGRSSHVYDAQWNDDAHHVLHVLLTGEDSGYYAAYAEEP 351 Query: 369 AEKLARCLREGFIYQGEPSPYRDNEVRGESSVELPPTAFVLFLQNHDQIGNRAQGERLTA 428 A KLARCL++GF+YQGE SPY E RGE S +LPPTAFV FLQNHDQIGNRA GERLT Sbjct: 352 AAKLARCLQQGFVYQGEVSPY-SGEPRGEPSADLPPTAFVNFLQNHDQIGNRAFGERLTV 410 Query: 429 LAHPDALRAAQALLLLSPQIPMLFMGEEYGASQPFYYFTSHADEKLADAVRNGRRNEFSR 488 LAHP AL AAQAL+LL+PQIPMLFMGEE+ A QPF YFTSH DE L AVR GRR EF+R Sbjct: 411 LAHPLALHAAQALVLLAPQIPMLFMGEEFCAVQPFLYFTSHRDEALVKAVREGRRREFAR 470 Query: 489 FPEFSDPEALDALPDPNSFSTFMASIPEPVSPDEDKSAGQWMGWCYR----LLLIRREAI 544 FP+F+DP L+ +PDPNSF+TF++SIPEP P +A C R LL IR+ I Sbjct: 471 FPQFADPALLEQIPDPNSFATFVSSIPEP-GPAPGSAA------CLRRVAELLHIRKLHI 523 Query: 545 TPYLPGAVALDAQAIGLKAVYARWRLNNGAVLNITVNLGEQPLRESLETL 594 PYL GA AL+A+AIG KAV+ARWRL+NG+VLNITVNL EQ ++ESL+ L Sbjct: 524 APYLRGARALEARAIGPKAVHARWRLSNGSVLNITVNLAEQAVQESLDQL 573 >ref|YP_001892467.1| malto-oligosyltrehalose trehalohydrolase [Ralstonia pickettii 12J] ref|YP_002983969.1| malto-oligosyltrehalose trehalohydrolase [Ralstonia pickettii 12D] gb|ACD29040.1| malto-oligosyltrehalose trehalohydrolase [Ralstonia pickettii 12J] gb|ACS65297.1| malto-oligosyltrehalose trehalohydrolase [Ralstonia pickettii 12D] Length = 613 Score = 663 bits (1711), Expect = 0.0, Method: Compositional matrix adjust. Identities = 359/591 (60%), Positives = 421/591 (71%), Gaps = 27/591 (4%) Query: 1 MNSPAPLALHPNNVRFHYRLPFGAEYLGNGRTSFRLWAPLAKTASVLID---GQRKVPMA 57 M +PAP RF + +PFGA L +G T FRLWAP A A + ID G + M Sbjct: 1 MTAPAP--------RFAHDMPFGATVLADGNTRFRLWAPDATAAWIDIDDTRGNESIRMD 52 Query: 58 AVDEGWFEVETDCEARSQYRYVLMSQTNGEISVPDPASRAQAGDVHADSVVIDASAYEWQ 117 A +GW+ + + YRY L ++ +SVPDPA+RAQ D+ S+V+D Y WQ Sbjct: 53 AEPDGWYAAVAPVGSGTCYRYRLTNRDGVTLSVPDPAARAQWQDIPGPSLVVDPQRYRWQ 112 Query: 118 TLDWRGRPWHETVLYELHVGALGGFAGVLQRLPELAELGITAVELMPVAEFPGAYNWGYD 177 DW+GRPWHETVLYELHVGALGGF GV RLPELA LGITA+ELMPVAEFPGA NWGYD Sbjct: 113 HADWQGRPWHETVLYELHVGALGGFKGVRGRLPELARLGITAIELMPVAEFPGARNWGYD 172 Query: 178 GVLPYAPDASYGTPEQLKQLIDTAHGLGMMVFLDVVYNHFGPDGNYLNSYAAPFFRTDST 237 GVLP+APDASYGTP+ LK LIDTAHGLGMMVFLDVVYNHFGPDGNYL+ YA FFR D Sbjct: 173 GVLPFAPDASYGTPDDLKALIDTAHGLGMMVFLDVVYNHFGPDGNYLHHYARSFFRDDVH 232 Query: 238 TPWGETIDFRRPEVADFFARNALYWLQEYRFDGLRLDAVHAISEQGWLRELARKVRRAIE 297 TPWG IDFR+P+V +FF +NAL WL EYRFDGLRLDAVHAI+E+ WL ELA +VR + E Sbjct: 233 TPWGAAIDFRKPQVREFFIQNALMWLMEYRFDGLRLDAVHAITERDWLGELAARVRLSAE 292 Query: 298 QEDADIGLSRRHVHLVLEHDGNAASLL-DGGTGKPGDGDKYDAQWNDDGHHVLHVLLTGE 356 RHVHLVLE++ NAASLL DG T GD +DAQWNDDGH+VLHVLLTGE Sbjct: 293 --------PGRHVHLVLENEHNAASLLRDGNT----HGD-FDAQWNDDGHNVLHVLLTGE 339 Query: 357 TGGYYSDYAVQPAEKLARCLREGFIYQGEPSPYRDNEVRGESSVELPPTAFVLFLQNHDQ 416 YY+ YA PA++LAR L++GF YQGEPSP DN RGE S LPPTAFVLFLQNHDQ Sbjct: 340 REAYYAAYADAPAQRLARVLQDGFCYQGEPSPIHDNAPRGEPSAHLPPTAFVLFLQNHDQ 399 Query: 417 IGNRAQGERLTALAHPDALRAAQALLLLSPQIPMLFMGEEYGASQPFYYFTSHADEKLAD 476 IGNRA GERLT LAHPDAL AAQ LLLLSPQIPMLFMGEE+G++ PF YFTSH LA+ Sbjct: 400 IGNRAFGERLTQLAHPDALHAAQVLLLLSPQIPMLFMGEEWGSTCPFQYFTSHHG-MLAE 458 Query: 477 AVRNGRRNEFSRFPEFSDPEALDALPDPNSFSTFMASIPEPVSPDEDKSAGQWMGWCYRL 536 AVR GRR EF++F F+DP + +PDPN T++AS P + E + +RL Sbjct: 459 AVREGRRREFAKFEAFADPHQRERIPDPNEELTYLASCPGEANLAEPAQLNT-LNRMHRL 517 Query: 537 LLIRREAITPYLPGAVALDAQAIGLKAVYARWRLNNGAVLNITVNLGEQPL 587 L +R I P LP A ALDA A+G ARWR+ +G+VL + +NL +QP+ Sbjct: 518 LALRHAEIIPRLPHARALDAVALGHAGAIARWRMGDGSVLTLMLNLADQPV 568 >ref|ZP_07673852.1| 4-alpha-D-((1->4)-alpha-D-glucano)trehalose trehalohydrolase [Ralstonia sp. 5_7_47FAA] gb|EFP67780.1| 4-alpha-D-((1->4)-alpha-D-glucano)trehalose trehalohydrolase [Ralstonia sp. 5_7_47FAA] Length = 613 Score = 656 bits (1693), Expect = 0.0, Method: Compositional matrix adjust. Identities = 363/622 (58%), Positives = 431/622 (69%), Gaps = 29/622 (4%) Query: 1 MNSPAPLALHPNNVRFHYRLPFGAEYLGNGRTSFRLWAPLAKTASVLID---GQRKVPMA 57 M +PAP RF + +PFGA L +G T FRLWAP A A + D G + M Sbjct: 1 MTAPAP--------RFAHDMPFGATVLADGNTRFRLWAPDATAAWIDFDDVRGDEAIRMD 52 Query: 58 AVDEGWFEVETDCEARSQYRYVLMSQTNGEISVPDPASRAQAGDVHADSVVIDASAYEWQ 117 +GW+ A + YRY L +Q +SVPDPA+RAQ D+ S+V+D Y+WQ Sbjct: 53 PEPDGWYAAVAPVGAGTCYRYRLTNQDGVTLSVPDPAARAQWQDIAGPSLVVDPQRYQWQ 112 Query: 118 TLDWRGRPWHETVLYELHVGALGGFAGVLQRLPELAELGITAVELMPVAEFPGAYNWGYD 177 DW+GRPWHETVLYELHVGALGGF GV RLPELA LGITA+ELMPVAEFPGA NWGYD Sbjct: 113 HADWQGRPWHETVLYELHVGALGGFKGVRGRLPELARLGITAIELMPVAEFPGARNWGYD 172 Query: 178 GVLPYAPDASYGTPEQLKQLIDTAHGLGMMVFLDVVYNHFGPDGNYLNSYAAPFFRTDST 237 GVLP+APDASYGTP+ LK LIDTAHGLG+MVFLDVVYNHFGPDGNYL+ YA FFR D Sbjct: 173 GVLPFAPDASYGTPDDLKALIDTAHGLGIMVFLDVVYNHFGPDGNYLHHYARSFFRDDVH 232 Query: 238 TPWGETIDFRRPEVADFFARNALYWLQEYRFDGLRLDAVHAISEQGWLRELARKVRRAIE 297 TPWG IDFR+P+V +FF +NAL WL EYRFDGLRLDAVHAI+E+ WL ELA +VR + E Sbjct: 233 TPWGAAIDFRKPQVREFFIQNALMWLMEYRFDGLRLDAVHAITERDWLGELAARVRLSAE 292 Query: 298 QEDADIGLSRRHVHLVLEHDGNAASLL-DGGTGKPGDGDKYDAQWNDDGHHVLHVLLTGE 356 RHVHLVLE++ NAASLL DG T GD +DAQWNDDGH+VLHVLLTGE Sbjct: 293 --------PGRHVHLVLENEHNAASLLRDGDT----HGD-FDAQWNDDGHNVLHVLLTGE 339 Query: 357 TGGYYSDYAVQPAEKLARCLREGFIYQGEPSPYRDNEVRGESSVELPPTAFVLFLQNHDQ 416 YY+ YA PA++LAR L++GF YQGEPSP +N RGE S LPPTAFVLFLQNHDQ Sbjct: 340 REAYYAAYAEAPAQRLARVLQDGFCYQGEPSPIHENAPRGEPSAHLPPTAFVLFLQNHDQ 399 Query: 417 IGNRAQGERLTALAHPDALRAAQALLLLSPQIPMLFMGEEYGASQPFYYFTSHADEKLAD 476 IGNRA GERLT LAHPDAL AAQ LLLLSPQIPMLFMGEE+G++ PF YFTSH LA+ Sbjct: 400 IGNRAFGERLTQLAHPDALYAAQVLLLLSPQIPMLFMGEEWGSTCPFQYFTSH-HGMLAE 458 Query: 477 AVRNGRRNEFSRFPEFSDPEALDALPDPNSFSTFMASIPEPVSPDEDKSAGQWMGWCYRL 536 AVR GRR EF++F F+DP + +PDPN TF+AS P + D + + +RL Sbjct: 459 AVREGRRREFAKFEAFADPHQRERIPDPNDELTFLASSPGEANL-ADPAQLNTLNRMHRL 517 Query: 537 LLIRREAITPYLPGAVALDAQAIGLKAVYARWRLNNGAVLNITVNLGEQPLRESLETLVT 596 L +R I P LP A ALDA A+G ARWR+ +G+VL + VNL +Q + ++ T++ Sbjct: 518 LALRHAEIIPRLPRARALDAVALGHAGALARWRMGDGSVLTLMVNLSDQAV--AVPTVLA 575 Query: 597 PXTTAARRRWKRSTSTATIACR 618 + + A IA R Sbjct: 576 GSPADLLHESREGAAAALIAHR 597 >ref|YP_003052329.1| malto-oligosyltrehalose trehalohydrolase [Methylovorus glucosetrophus SIP3-4] gb|ACT51802.1| malto-oligosyltrehalose trehalohydrolase [Methylovorus glucosetrophus SIP3-4] Length = 651 Score = 647 bits (1670), Expect = 0.0, Method: Compositional matrix adjust. Identities = 324/582 (55%), Positives = 394/582 (67%), Gaps = 22/582 (3%) Query: 11 PNNVRFHYRLPFGAEYLGNGRTSFRLWAPLAKTASVLIDGQRKVPMAA-VDEGWFEVETD 69 P+ F YRL GA+ L T FRLWAP A+ +++D +PM + GWF + + Sbjct: 31 PSRNTFRYRLAGGAQLLSLAETEFRLWAPNARQVDLILDKGTFIPMQQEANTGWFSTQAE 90 Query: 70 CEARSQYRYVLMSQTNGEISVPDPASRAQAGDVHADSVVIDASAYEWQTLDWRGRPWHET 129 C A ++YRY +++ E+ VPDP SR Q G VH +SVV+D AY W+ L W+GRPWH+T Sbjct: 91 CGAGTEYRYRAINKEGNELLVPDPYSRRQTGSVHGNSVVVDPQAYRWRHLQWKGRPWHDT 150 Query: 130 VLYELHVGALGGFAGVLQRLPELAELGITAVELMPVAEFPGAYNWGYDGVLPYAPDASYG 189 V+YE H G +GGF GV +L ELA +G TA+ELMP+A FPGA+NWGYDGVL +AP SYG Sbjct: 151 VIYEAHAGVMGGFIGVRAKLAELAGMGFTAIELMPIASFPGAHNWGYDGVLQFAPHVSYG 210 Query: 190 TPEQLKQLIDTAHGLGMMVFLDVVYNHFGPDGNYLNSYAAPFFRTDSTTPWGETIDFRRP 249 TP++LK L+D AH LG+ +FLDVVYNHFGPDGNYL YA FF TPWG+ IDF P Sbjct: 211 TPDELKALVDEAHALGLSIFLDVVYNHFGPDGNYLWHYAPEFFNHAYKTPWGDAIDFAEP 270 Query: 250 EVADFFARNALYWLQEYRFDGLRLDAVHAISEQGWLRELARKVRRAIEQEDADIGLSRRH 309 V FF N YWL+EYRFDGLR DA HAI + WL + ++VR + +RH Sbjct: 271 HVQQFFVDNIYYWLEEYRFDGLRFDACHAIWNKAWLGDTIKQVREHYQ--------GKRH 322 Query: 310 VHLVLEHDGNAASLLDGGTGKPGDGDKYDAQWNDDGHHVLHVLLTGETGGYYSDYAVQPA 369 VHLV E+D NAASLL GD++ AQWNDDGHHVLHVLLTGET GYYSDYA A Sbjct: 323 VHLVAENDDNAASLL---------GDRFVAQWNDDGHHVLHVLLTGETEGYYSDYAKHAA 373 Query: 370 EKLARCLREGFIYQGEPSPYRDNEVRGESSVELPPTAFVLFLQNHDQIGNRAQGERLTAL 429 EKLARCL EGF+YQGE S +R EVRGE+S LP ++FVLFLQNHDQIGNR GERLT L Sbjct: 374 EKLARCLAEGFVYQGEVSQHRQGEVRGENSQHLPLSSFVLFLQNHDQIGNRPFGERLTTL 433 Query: 430 AHPDALRAAQALLLLSPQIPMLFMGEEYGASQPFYYFTSHADEKLADAVRNGRRNEFSRF 489 ALRAA L+LLSPQIP+LFMGEE+GA+QPF YFT H + LA AV GRR EFS F Sbjct: 434 VPEPALRAAMGLVLLSPQIPLLFMGEEFGATQPFLYFTDHENPDLAAAVWEGRRREFSTF 493 Query: 490 PEFSDPEALDALPDPNSFSTFMASIPEPV---SPDEDKSAGQWMGWCYRLLLIRREAITP 546 +F+ + +P+PN +F ASIP PV PD ++ A +W W +LL +R + I P Sbjct: 494 EKFTKASFAEKIPNPNDIESFNASIPRPVGSHDPDINR-ASEWQAWIRQLLSLRHQHIVP 552 Query: 547 YLPGAVALDAQAIGLKAVYARWRLNNGAVLNITVNLGEQPLR 588 YL L A AIG AV ARWRL NGA L I +NLG+ P+ Sbjct: 553 YLEHTRTLSAYAIGPAAVKARWRLGNGATLEILLNLGDSPVH 594 >ref|YP_004040883.1| malto-oligosyltrehalose trehalohydrolase [Methylovorus sp. MP688] gb|ADQ85647.1| malto-oligosyltrehalose trehalohydrolase [Methylovorus sp. MP688] Length = 636 Score = 643 bits (1659), Expect = 0.0, Method: Compositional matrix adjust. Identities = 321/582 (55%), Positives = 393/582 (67%), Gaps = 22/582 (3%) Query: 11 PNNVRFHYRLPFGAEYLGNGRTSFRLWAPLAKTASVLIDGQRKVPMAA-VDEGWFEVETD 69 P+ YRL GA+ L T FRLWAP A+ +++D +PM + GWF + + Sbjct: 16 PSRNTLRYRLAGGAQLLSLAETEFRLWAPNARQVDLILDKGTVIPMQQEANTGWFSTQAE 75 Query: 70 CEARSQYRYVLMSQTNGEISVPDPASRAQAGDVHADSVVIDASAYEWQTLDWRGRPWHET 129 C A ++YRY +++ E+ VPDP SR Q G VH SVV+D +Y W+ L W+GRPWHET Sbjct: 76 CGAGTEYRYRAINKEGNELLVPDPYSRRQTGSVHGSSVVVDPQSYRWRHLPWKGRPWHET 135 Query: 130 VLYELHVGALGGFAGVLQRLPELAELGITAVELMPVAEFPGAYNWGYDGVLPYAPDASYG 189 V+YE H G +GGF GV +L ELA +G TA+ELMP+A FPGA+NWGYDGVL +AP SYG Sbjct: 136 VIYEAHAGVMGGFVGVRAKLAELAGMGFTAIELMPIASFPGAHNWGYDGVLQFAPHVSYG 195 Query: 190 TPEQLKQLIDTAHGLGMMVFLDVVYNHFGPDGNYLNSYAAPFFRTDSTTPWGETIDFRRP 249 +P++LK L+D AH LG+ +FLDVVYNHFGPDGNYL YA FF TPWG+ IDF P Sbjct: 196 SPDELKALVDEAHALGLSIFLDVVYNHFGPDGNYLWHYAPEFFNHAYKTPWGDAIDFAEP 255 Query: 250 EVADFFARNALYWLQEYRFDGLRLDAVHAISEQGWLRELARKVRRAIEQEDADIGLSRRH 309 V FF N YWL+EYRFDGLR DA HAI + WL + +++R + +RH Sbjct: 256 HVQQFFVDNIYYWLEEYRFDGLRFDACHAIWNKAWLGDTIKQIREHYQ--------GKRH 307 Query: 310 VHLVLEHDGNAASLLDGGTGKPGDGDKYDAQWNDDGHHVLHVLLTGETGGYYSDYAVQPA 369 VHLV E+D NAASLL GD++ AQWNDDGHHVLHVLLTGET GYYSDYA A Sbjct: 308 VHLVAENDDNAASLL---------GDRFVAQWNDDGHHVLHVLLTGETEGYYSDYAEHAA 358 Query: 370 EKLARCLREGFIYQGEPSPYRDNEVRGESSVELPPTAFVLFLQNHDQIGNRAQGERLTAL 429 EKLARCL EGF+YQGE S +R EVRGE+S LP ++FVLFLQNHDQIGNR GERLT L Sbjct: 359 EKLARCLAEGFVYQGEVSQHRQGEVRGENSQHLPLSSFVLFLQNHDQIGNRPFGERLTTL 418 Query: 430 AHPDALRAAQALLLLSPQIPMLFMGEEYGASQPFYYFTSHADEKLADAVRNGRRNEFSRF 489 ALRAA L+LLSPQIP+LFMGEE+GA+QPF YFT H + +LA AV GRR EFS F Sbjct: 419 VPEPALRAAMGLVLLSPQIPLLFMGEEFGATQPFLYFTDHENPELAAAVWEGRRREFSTF 478 Query: 490 PEFSDPEALDALPDPNSFSTFMASIPEPV---SPDEDKSAGQWMGWCYRLLLIRREAITP 546 +F+ + +P+PN +F ASIP PV PD ++ A +W W +LL +R + I P Sbjct: 479 EKFTKASFAEKIPNPNDIESFNASIPRPVGSHDPDINR-ASEWQAWIRQLLSLRHQHIVP 537 Query: 547 YLPGAVALDAQAIGLKAVYARWRLNNGAVLNITVNLGEQPLR 588 YL L A AIG AV ARWRL NGA L I +NLG+ P+ Sbjct: 538 YLEHTRTLSAYAIGPAAVKARWRLGNGATLEILLNLGDSPVH 579